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- 저자 : Guoyong Chen (검색결과 5 건)
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Drainage procedure for pancreatolithiasis: re-examination of the pancreatic duct diameter standard
Guoyong Chen,Yu You,Hongxian Yan,Junchuang He,Jianping Gong,Sidong Wei 대한외과학회 2020 Annals of Surgical Treatment and Research(ASRT) Vol.98 No.4
Purpose: Pancreatic duct decompression relieves pancreatic duct stone (PDS)-associated abdominal pain, though a consensus indication for the drainage procedure of the main pancreatic duct (MPD) is lacking. Moreover, major prognostic factors for postsurgical long-term pain relief and recurrence are largely unknown. Methods: The clinical outcomes of 65 consecutive PDS patients undergoing surgery from 2008–2012 with 3+ years of follow-up were assessed. Results: At postsurgical follow-up (median, 4.5 years; range, 3–7 years; procedure: Partington, n = 32; Frey, n = 27; pancreatoduodenectomy, n = 3; distal pancreatectomy, n = 3), the early complication and complete stone clearance rates were 29.2% and 97%, respectively. Long-term, complete and partial pain relief were 93.9%, 83.1%, and 10.8%, respectively. The risk of pancreatic fistula was higher in the <8 mm group than in the >8 mm group (P < 0.05), and 80% of the pancreatic fistula cases occurred in the <8 mm group. A shorter pain duration (P = 0.007), smaller MPD diameter (P = 0.04), and lower Izbicki pain score (P < 0.001) predicted long-term pain relief. Pain recurrence after initial remission occurred in 5 patients and was only related to pain duration (P = 0.02). Stone recurrence and pancreatic exocrine functional and endocrine functional deterioration occurred in 2, 5, and 11 patients, respectively. Conclusion: Surgery provides excellent stone clearance, long-term pain relief, and acceptable postoperative morbidity. Using 8 mm as the criterion for drainage surgery can minimize the postoperative pancreatic fistula risk. Individualized and timely surgical treatment may improve the effect of surgery.
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A Novel Distributed Clustering-based MDS Algorithm for Nodes Localization in WSNs
Guoyong Dai,Chunyu Miao,Yidong Li,Keji Mao,Qingzhang Chen 보안공학연구지원센터 2015 International Journal of Grid and Distributed Comp Vol.8 No.2
Localization of sensors nodes is a key and fundamental issue in wireless sensor networks due to random deployment. In this paper, we propose a tree based clustering (TBC) multidimensional scaling algorithm for wireless sensor networks with the purpose of overcoming the shortage of classical MDS algorithms in its localization accuracy and computing complexity. Clustering is adopted to degrade the problem scale in our approach and a moderate number of common nodes between clusters are kept during clustering. Inner cluster local coordinates are calculated and then mapped into global coordinates according to the tree structure formed by clustering. Simulations on MATLAB are conducted and the results show that the proposed algorithm has better localization coverage and higher accuracy than the traditional MDS based algorithms.
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A Novel Coverage Holes Discovery Algorithm Based on Voronoi Diagram in Wireless Sensor Networks
Guoyong Dai,Hexin Lv,Luyi Chen,Binbin Zhou,Ping Xu 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.3
Coverage is a key and fundamental problem in wireless sensor networks. To provide high quality of service, high coverage ratio of sensor nodes in monitored area should be assured. Coverage holes may lead to routing failure and degrade the quality of service. A novel coverage hole discovery algorithm, VCHDA, is proposed for wireless sensor networks in this paper. The proposed algorithm is based on the well-known Voronoi diagram. It can recognize coverage holes and label the border nodes of coverage holes effectively. Simulations are conducted and the results show that the proposed algorithm is effective and with high accuracy.
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Honglin Xu,Haifeng Miao,Guanghong Chen,Guoyong Zhang,Yue Hua,Yuting Wu,Tong Xu,Changlei Hu,Mingjie Pang,Leyi Tan,Xin Han,Bin Liu,Yingchun Zhou 고려인삼학회 2023 Journal of Ginseng Research Vol.47 No.6
Background: Myocardial fibrosis post-myocardial infarction (MI) can induce maladaptive cardiacremodeling as well as heart failure. Although 20(S)-ginsenoside Rg3 (Rg3) has been applied to cardiovasculardiseases, its efficacy and specific molecular mechanism in myocardial fibrosis are largely unknown. Herein, we aimed to explore whether TGFBR1 signaling was involved in Rg3's anti-fibrotic effectpost-MI. Methods: Left anterior descending (LAD) coronary artery ligation-induced MI mice and TGF-b1-stimulated primary cardiac fibroblasts (CFs) were adopted. Echocardiography, hematoxlin-eosin andMasson staining, Western-blot and immunohistochemistry, CCK8 and Edu were used to study the effectsof Rg3 on myocardial fibrosis and TGFBR1 signaling. The combination mechanism of Rg3 and TGFBR1 wasexplored by surface plasmon resonance imaging (SPRi). Moreover, myocardial Tgfbr1-deficient mice andTGFBR1 adenovirus were adopted to confirm the pharmacological mechanism of Rg3. Results: In vivo experiments, Rg3 ameliorated myocardial fibrosis and hypertrophy and enhanced cardiacfunction. Rg3-TGFBR1 had the 1.78 10 7 M equilibrium dissociation constant based on SPRi analysis,and Rg3 inhibited the activation of TGFBR1/Smads signaling dose-dependently. Cardiac-specific Tgfbr1knockdown abolished Rg3's protection against myocardial fibrosis post-MI. In addition, Rg3 downregulatedthe TGF-b1-mediated CFs growth together with collagen production in vitro through TGFBR1signaling. Moreover, TGFBR1 adenovirus partially blocked the inhibitory effect of Rg3. Conclusion: Rg3 improves myocardial fibrosis and cardiac function through suppressing CFs proliferationalong with collagen deposition by inactivation of TGFBR1 pathway.
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Impact performance for high frequency hydraulic rock drill drifter with sleeve valve
Guo, Yong,Yang, Shu Yi,Liu, De Shun,Zhang, Long Yan,Chen, Jian Wen Korean Society for Fluid machinery 2016 International journal of fluid machinery and syste Vol.9 No.1
A high frequency hydraulic rock drill drifter with sleeve valve is developed to use on arm of excavator. In order to ensure optimal working parameters of impact system for the new hydraulic rock drill drifter controlled by sleeve valve, the performance test system is built using the arm and the hydraulic source of excavator. The evaluation indexes are gained through measurement of working pressure, supply oil flow and stress wave. The relations of working parameters to impact system performance are analyzed. The result demonstrates that the maximum impact energy of the drill drifter is 98.34J with impact frequency of 71HZ. Optimal pressure of YZ45 rock drill is 12.8 MPa-13.6MPa, in which the energy efficiency reaches above 58.6%, and feature moment of energy distribution is more than 0.650.
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