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      • SCOPUS

        Appearance-Order-Based Schema Matching

        Guohui Ding,Keyan Cao,Guoren Wang,Dong Han 한국정보과학회 2014 Journal of Computing Science and Engineering Vol.8 No.2

        Schema matching is widely used in many applications, such as data integration, ontology merging, data warehouse and dataspaces. In this paper, we propose a novel matching technique that is based on the order of attributes appearing in the schema structure of query results. The appearance order embodies the extent of the importance of an attribute for the user examining the query results. The core idea of our approach is to collect statistics about the appearance order of attributes from the query logs, to find correspondences between attributes in the schemas to be matched. As a first step, we employ a matrix to structure the statistics around the appearance order of attributes. Then, two scoring functions are considered to measure the similarity of the collected statistics. Finally, a traditional algorithm is employed to find the mapping with the highest score. Furthermore, our approach can be seen as a complementary member to the family of the existing matchers, and can also be combined with them to obtain more accurate results. We validate our approach with an experimental study, the results of which demonstrate that our approach is effective, and has good performance.

      • SCOPUS

        Appearance-Order-Based Schema Matching

        Ding, Guohui,Cao, Keyan,Wang, Guoren,Han, Dong Korean Institute of Information Scientists and Eng 2014 Journal of Computing Science and Engineering Vol.8 No.2

        Schema matching is widely used in many applications, such as data integration, ontology merging, data warehouse and dataspaces. In this paper, we propose a novel matching technique that is based on the order of attributes appearing in the schema structure of query results. The appearance order embodies the extent of the importance of an attribute for the user examining the query results. The core idea of our approach is to collect statistics about the appearance order of attributes from the query logs, to find correspondences between attributes in the schemas to be matched. As a first step, we employ a matrix to structure the statistics around the appearance order of attributes. Then, two scoring functions are considered to measure the similarity of the collected statistics. Finally, a traditional algorithm is employed to find the mapping with the highest score. Furthermore, our approach can be seen as a complementary member to the family of the existing matchers, and can also be combined with them to obtain more accurate results. We validate our approach with an experimental study, the results of which demonstrate that our approach is effective, and has good performance.

      • <sup>99</sup>Tc immobilization from off-gas waste streams using nickel-doped iron spinel

        Wang, Guohui,Um, Wooyong,Kim, Dong-Sang,Kruger, Albert A. Elsevier 2019 Journal of hazardous materials Vol.364 No.-

        <P><B>Abstract</B></P> <P>Technetium-99 (<SUP>99</SUP>Tc) incorporation within stable spinel phases is a novel method for <SUP>99</SUP>Tc removal and immobilization from waste streams. In this study, transformation of Ni-doped Fe(OH)<SUB>2</SUB>(s) to spinel minerals, e.g. trevorite (NiFe<SUB>2</SUB>O<SUB>4</SUB>), is explored as a method for removing <SUP>99</SUP>Tc from Hanford Waste Treatment and Immobilization Plant (WTP) primary off-gas waste stream simulant. The Fe(OH)<SUB>2</SUB>(s) transformation process was found to reduce <SUP>99</SUP>Tc(VII) to <SUP>99</SUP>Tc(IV) and incorporate reduced Tc(VI) into the produced spinel simultaneously. Nickel doping was applied in the mineral transformation to inhibit potential reoxidation of <SUP>99</SUP>Tc(IV). Solid phase characterization by XRD and XANES confirmed the formation of nickel substituted ferric-spinel, and suggest incorporation of <SUP>99</SUP>Tc(IV) in the final spinel. Furthermore, in the primary off-gas stream, which contains both redox-sensitive contaminants Cr(VI) and <SUP>99</SUP>Tc(VII), results from solution analysis and solid digestion indicate that nearly 100% Cr and over 80% <SUP>99</SUP>Tc can be simultaneously removed by adding Fe(OH)<SUB>2</SUB>(s) to solution with a solid to solution ratio of 5 g/L under near neutral and alkaline conditions. The <SUP>99</SUP>Tc removal approach developed herein provides an alternative treatment method to eliminate the proposed recycle process of the off-gas waste stream, which ultimately can reduce WTP mission cost and operation time.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Ni-doped Fe(OH)<SUB>2</SUB>(s) – spinel transformation process at low temperatures. </LI> <LI> <SUP>99</SUP>Tc(VII) reduced to <SUP>99</SUP>Tc(IV) and incorporated into produced spinel simultaneously. </LI> <LI> Fe(OH)<SUB>2</SUB>(s) can remove both Cr and <SUP>99</SUP>Tc from an off-gas simulant. </LI> </UL> </P>

      • Discovery of the leinamycin family of natural products by mining actinobacterial genomes

        Pan, Guohui,Xu, Zhengren,Guo, Zhikai,Hindra,Ma, Ming,Yang, Dong,Zhou, Hao,Gansemans, Yannick,Zhu, Xiangcheng,Huang, Yong,Zhao, Li-Xing,Jiang, Yi,Cheng, Jinhua,Van Nieuwerburgh, Filip,Suh, Joo-Won,Duan National Academy of Sciences 2017 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.114 No.52

        <P>Nature's ability to generate diverse natural products from simple building blocks has inspired combinatorial biosynthesis. The knowledge-based approach to combinatorial biosynthesis has allowed the production of designer analogs by rational metabolic pathway engineering. While successful, structural alterations are limited, with designer analogs often produced in compromised titers. The discovery-based approach to combinatorial biosynthesis complements the knowledge-based approach by exploring the vast combinatorial biosynthesis repertoire found in Nature. Here we showcase the discovery-based approach to combinatorial biosynthesis by targeting the domain of unknown function and cysteine lyase domain (DUF-SH) didomain, specific for sulfur incorporation from the leinamycin (LNM) biosynthetic machinery, to discover the LNM family of natural products. By mining bacterial genomes from public databases and the actinomycetes strain collection at The Scripps Research Institute, we discovered 49 potential producers that could be grouped into 18 distinct clades based on phylogenetic analysis of the DUF-SH didomains. Further analysis of the representative genomes from each of the clades identified 28 lnm-type gene clusters. Structural diversities encoded by the LNM-type biosynthetic machineries were predicted based on bioinformatics and confirmed by in vitro characterization of selected adenylation proteins and isolation and structural elucidation of the guangnanmycins and weishanmycins. These findings demonstrate the power of the discovery-based approach to combinatorial biosynthesis for natural product discovery and structural diversity and highlight Nature's rich biosynthetic repertoire. Comparative analysis of the LNM-type biosynthetic machineries provides outstanding opportunities to dissect Nature's biosynthetic strategies and apply these findings to combinatorial biosynthesis for natural product discovery and structural diversity.</P>

      • SCISCIESCOPUS

        Effect of Technetium-99 sources on its retention in low activity waste glass

        Luksic, Steven A.,Kim, Dong-Sang,Um, Wooyong,Wang, Guohui,Schweiger, Michael J.,Soderquist, Chuck Z.,Lukens, Wayne,Kruger, Albert A. Elsevier 2018 JOURNAL OF NUCLEAR MATERIALS Vol.503 No.-

        <P><B>Abstract</B></P> <P>Small-scale crucible melting tests on simulated waste glass were performed with technetium-99 (Tc-99) introduced as different species in a representative low activity waste simulant. The glass saw an increase in Tc-99 retention when TcO<SUB>2</SUB>∙2H<SUB>2</SUB>O and various Tc-minerals containing reduced tetravalent Tc were used compared to tests in which pertechnetate with heptavalent Tc was used. We postulate that the increase of Tc retention is likely caused by different reaction paths for Tc incorporation into glass during early stages of melting, rather than the low volatility of reduced tetravalent Tc compounds, which has been a generally accepted idea. Additional studies are needed to clarify the exact mechanisms relevant to the effect of reduced Tc compounds on Tc incorporation into or volatilization from the glass melt.</P>

      • KCI등재

        Co-located and space-shared multiple-input multiple-output antenna module and its applications in 12 × 12 multiple-input multiple-output systems

        Longyue Qu,Haiyan Piao,Guohui Dong 한국전자통신연구원 2023 ETRI Journal Vol.45 No.2

        In this study, we developed a co-located and space-shared multiple-input multiple-output (MIMO) antenna module with a modular design and high integration level. The proposed antenna pair includes a half-wavelength loop antenna and a dipole-type antenna printed on the front and back sides of a compact modular board. Owing to their modal orthogonality, these two independent antenna elements are highly self-isolated and free of additional decoupling components, even though they are assembled at the same location and within the same space. Thus, the proposed antenna is attractive in 5G MIMO systems. Furthermore, the proposed co-located and space-shared MIMO antenna module was employed in a 5G smartphone to verify their radiation and diversity performances. A 12 × 12 MIMO antenna system was simulated and fabricated using the proposed module. Based on the results, the proposed module can be employed in large-scale MIMO antenna systems for current and future terminal devices owing to its high integration, compactness, simple implementation, and inherent isolation.

      • SCISCIESCOPUS

        Enhanced <sup>99</sup>Tc retention in glass waste form using Tc(IV)-incorporated Fe minerals

        Um, Wooyong,Luksic, Steven A.,Wang, Guohui,Saslow, Sarah,Kim, Dong-Sang,Schweiger, Michael J.,Soderquist, Chuck Z.,Bowden, Mark E.,Lukens, Wayne W.,Kruger, Albert A. Elsevier 2017 JOURNAL OF NUCLEAR MATERIALS Vol.495 No.-

        <P><B>Abstract</B></P> <P>Technetium (<SUP>99</SUP>Tc) immobilization by doping into iron oxide mineral phases may alleviate the problems with Tc volatility during vitrification of nuclear waste. Because reduced Tc, Tc(IV), substitutes for Fe(III) in the crystal structure by a process of Tc reduction from Tc(VII) to Tc(IV) followed by co-precipitation of Fe oxide minerals, two Tc-incorporated Fe minerals (Tc-goethite and Tc-magnetite/maghemite) were prepared and tested for Tc retention in glass melt samples at temperatures between 600 and 1000 °C. After being cooled, the solid glass specimens prepared at different temperatures at 600, 800, and 1000 °C were analyzed for Tc oxidation state using Tc K-edge XANES. In most samples, Tc was partially (<60%) oxidized from Tc(IV) to Tc(VII) as the melt temperature increased up to 600 °C. However, most of Tc(IV) was completely (>95%) oxidized to Tc(VII) at temperature above 800 °C. Tc retention in glass melt samples prepared using Tc-incorporated Fe minerals were slightly higher (∼10%) than in glass prepared using KTcO<SUB>4</SUB> because of limited and delayed Tc volatilization.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Reduced Tc(IV) can be incorporated within an Fe oxide mineral structure. </LI> <LI> Tc-incorporated Fe minerals can increase Tc retention in glass waste forms. </LI> <LI> Increased Tc retention in glass can reduce the cost of waste treatment. </LI> </UL> </P>

      • KCI등재

        Complete genome sequence of the Pogostemon cablin bacterial wilt pathogen Ralstonia solanacearum strain SY1

        Sun Yunhao,Su Yutong,Hussain Ansar,Xiong Lina,Li Chunji,Zhang Jie,Meng Zhen,Dong Zhangyong,Yu Guohui 한국유전학회 2023 Genes & Genomics Vol.45 No.1

        Background Ralstonia solanacearum causes bacterial wilt of Pogostemon cablin which is an important aromatic herb and also the main materials of COVID-19 therapeutic traditional drugs. However, we are lacking the information on the genomic sequences of R. solanacearum isolated from P. cablin. Objective The acquisition and analysis of this whole-genome sequence of the P. cablin bacterial wilt pathogen. Methods An R. solanacearum strain, named SY1, was isolated from infected P. cablin plants, and the complete genome sequence was sequenced and analyzed. Results The SY1 strain contains a 3.70-Mb chromosome and a 2.18-Mb megaplasmid, with GC contents of 67.57% and 67.41%, respectively. A total of 3308 predicted genes were located on the chromosome and 1657 genes were located in the megaplasmid. SY1 strain has 273 unique genes compared with five representative R. solanacearum strains, and these genes were enriched in the plant–pathogen interaction pathway. SY1 possessed a higher syntenic relationship with phylotype I strains, and the arsenal of type III effectors predicted in SY1 were also more closely related to those of phylotype I strains. SY1 contained 14 and 5 genomic islands in its chromosome and megaplasmid, respectively, and two prophage sequences in its chromosome. In addition, 215 and 130 genes were annotated as carbohydrate-active enzymes and antibiotic resistance genes, respectively. Conclusion This is the first genome-scale assembly and annotation for R. solanacearum which isolated from infected P. cablin plants. The arsenal of virulence and antibiotic resistance may as the determinants in SY1 for infection of P. cablin plants.

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