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Guo-Wei Fan,Xue-Ying Lv,Ying Song,Huan-Yu Zhao,Liu Zhang 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.8
Nonparallel ground track imaging of optical remote sensing satellite is an efficient imaging mode which could realize one-time transit imaging of complex observation tasks due to its fast and flexible imaging capability, and has attracted more attentions in the earth observation field recently. In this paper, an off-line attitude trajectory planning and on-line moving horizon attitude tracking control scheme based on optimal control idea is designed to satisfy the imaging requirement of high-performance attitude control oriented to nonparallel ground track imaging. Considering the entire satellite attitude adjustment of the drift angle, based on the geometric relationship of sapce vectors and the coordinate transformation principle, the three-axis attitude calculation of the precise pointing of key feature targets in the interested ground curve strip is conducted. Taking the attitude orientation as the constraint, the pseudospectral method is used following the established agile satellite control model to design the optimal trajectory of the attitude manever and the feedforward control torque of actuator for nonparallel ground track imaging. A moving horizon tracking control law based on the nonlinear error control model is designed to realize the highprecision attitude tracking control. The feasibility and effectiveness of the proposed control scheme are illustrated by numerical and imaging simulations.
Bioinformatics Analysis Reveals Connection of Squamous Cell Carcinoma and Adenocarcinoma of the Lung
Fan, Wei-Dong,Zhang, Xian-Quan,Guo, Hui-Lin,Zeng, Wei-Wei,Zhang, Ni,Wan, Qian-Qian,Xie, Wen-Yao,Cao, Jin,Xu, Chang-Hua Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4
Squamous cell carcinoma and adenocarcinoma are the major histological types of non-small cell lung cancer. Because they differ on the basis of histopathological and clinical characteristics and their relationship with smoking, their etiologies may be different; for example, different tumor suppressor genes may be related to the genesis of each type. We used microarray data to construct three regulatory networks to identify potential genes related to lung adenocarcinoma and squamous cell carcinoma and investigated the similarity and specificity of them. In the network, some of the observed transcription factors and target genes had been previously proven to be related to lung adenocarcinoma and squamous cell carcinoma. We also found some new transcription factors and target genes related to SCC. The results demonstrated that regulatory network analysis is useful in connection analysis between lung adenocarcinoma and squamous cell carcinoma.
Multicentre Hospital-based Case-control Study of Diffuse Large B-cell Lymphoma in Shanghai, China
Fan, Rong,Zhang, Lu-Yao,Wang, Hong,Yang, Bo,Han, Tao,Zhao, Xiao-Li,Wang, Wei,Wang, Xiao-Qin,Lin, Guo-Wei Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.7
Background: Several potential risk factors have been identified for diffuse large B-cell lymphoma (DLBCL); however, epidemiological studies investigating the association between these risk factors and DLBCL have yielded inconsistent results. Objectives: To investigate potential medical, lifestyle, and environmental risk factors of DLBCL in Shanghai, China through a hospital-based case-control study. Method: One-hundred-and-forty-seven newly diagnosed DLBCL patients and 294 sex- and age-matched controls were recruited from 11 hospitals in Shanghai between 2003 and 2007. A standardized structured questionnaire was used to obtain patient data on demographics, medical history, family history, lifestyle, and environmental exposures. Conditional logistic regression models were used to estimate odds ratios (ORs), with 95% confidence intervals (CIs), for risk associated with each data category. Results: History of tuberculosis (TB) infection and "living on a farm" were positively associated with DLBCL (TB: OR=3.05, 95% CI: 1.19-7.80; farm: OR=1.82, 95% CI: 1.21-2.73). In contrast, taking traditional Chinese medicine was negatively associated with DLBCL (OR=0.36, 95% CI: 0.14-0.89). No significant correlation with DLBCL risk was found for any of the other potential risk factors (p>0.05), including but not limited to hair dyes, alcohol drinking, smoking, and home/workplace renovation within one year. Conclusions: Consistent with results from previous studies in other DLBCL case populations, traditional Chinese medicine appeared to have a direct or indirect protective effect against DLBCL. However, this study also identified a possible predisposition for DLBCL in TB sufferers and farmers.
Survival Analysis of Oral Squamous Cell Carcinoma in a Subgroup of Young Patients
Fan, Yi,Zheng, Lei,Mao, Ming-Hui,Huang, Ming-Wei,Liu, Shu-Ming,Zhang, Jie,Li, Sheng-Lin,Zheng, Lei,Zhang, Jian-Guo Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20
Oral squamous cell carcinoma (OSCC) is predominantly a disease of middle-aged men with long-term exposure to tobacco and alcohol. An increasing trend has been reported at a younger age worldwide. Clinical records of 100 patients under the age of 45 years treated specifically for oral cavity SCC in our hospital during a 10-year period were retrospectively analyzed to calculate the survival rates. An obvious male predominance coincided with smoking trend among Chinese young individuals and female patients were more likely to have no traditional risk factors such as smoking or drinking. The 5-year overall survival rate and disease-free survival rate were 61.0% and 75.5%, respectively, consistent with other published series over the decade showing a relatively better survival among the young. No significant differences clearly correlated with outcome when comparing non-smokers non-drinkers to ever-smokers and ever drinkers (P>0.05). Overall survival rate and disease free survival rate was found to be significantly higher in patients with early-stage disease than with advanced stage disease (P=0.001, P=0.009 respectively). The strong influence of clinical stage on prognosis emphasizes the importance of early diagnosis and treatment of oral malignancies for this unique clinical subgroup.
Simulated Long-Term Vegetation–Climate Feedbacks in the Tibetan Plateau
Wei Hua,Zouxin Lin,Donglin Guo,Guangzhou Fan,Yongli Zhang,Kaiqin Yang,Qin Hu,Lihua Zhu 한국기상학회 2019 Asia-Pacific Journal of Atmospheric Sciences Vol.55 No.1
The Tibetan Plateau (TP) is an important region of land–atmosphere interactions with high climate variability. In this study, an atmosphere–vegetation interaction model was applied to explore the possible responses of vegetation to climate warming, and to assess the impacts of land cover change on the land surface physical processes across the TP. Results showed that long-term warming over the TP could influence vegetation growth via different mechanisms. Most likely, increased temperature would enhance the physiological activity in most high cold areas on the TP, whereas high temperature would inhibit vegetation growth by increasing respiration in areas with favorable water and temperature conditions. In addition, for areas where the climate is warmer but not wetter, higher temperature could influence photosynthesis via the moisture condition of the vegetation rather than by modulating respiration. Numerical simulations demonstrated that vegetation could control the land surface–atmosphere energy balance effectively. The change of land cover from vegetated land to desert steppe decreased the net radiation absorbed by the surface, weakening the surface thermal effects, and reducing sensible and latent heat fluxes. Furthermore, sensitivity simulations also revealed that global warming would likely accelerate vegetation growth in most areas of the TP, resulting in increased surface heat flux.
Shear strength evaluation of RC solid piers of high-speed railway bridges in China
Wei Guo,Chao Fan,Yao Cui,Chen Zeng,Lizhong Jiang,Zhiwu Yu 국제구조공학회 2021 Structural Engineering and Mechanics, An Int'l Jou Vol.78 No.4
Piers are the main lateral force-resisting members of high-speed railway (HSR) bridges used in China and are characterized by low axial load ratios, low longitudinal reinforcement ratios, low stirrup ratios, and high shear span ratios. It is well known that flexural, flexural-shear, and shear failures of piers may occur during an earthquake. In this study, a new shear strength model was developed to simulate the seismic failure of HSR solid piers accurately. First, low cyclic-loading test data of solid piers obtained in recent years were collected to set up a database for model verification. Second, based on the test database, the applicability of existing shear strength models was evaluated. Finally, a new shear strength model for HSR solid piers with round-ended cross-sections was derived based on the truss model and ultimate equilibrium theory. In comparison with existing models, it was demonstrated that the proposed model could be used to predict the shear strength of HSR piers more accurately.