Laboratory and field performance of Trichopria drosophilae reared on Drosophila melanogaster and D. Suzukii

Gonzalez-Cabrera Jaime,Moreno-Carrillo Gabriel,Lopez-Juarez Alejandro A.,Anguiano-Amezcua Juan A.,Sanchez-Gonzalez Jorge A.,Mendoza-Ceballos Mario Y.,Arredondo-Bernal Hugo C. 한국응용곤충학회 2023 Journal of Asia-Pacific Entomology Vol.26 No.2

Two colonies of the parasitoid Trichopria drosophilae (Perkins) (Hymenoptera: Diapriidae) are reproduced using a mass rearing approach in Mexico. The first colony uses the worldwide commercial host Drosophila melanogaster Meigen (Diptera: Drosophilidae) reared on an artificial diet (=T. drosophilae-Dm), while the second colony uses D. suzukii Matsumura reared on fresh banana (=T. drosophilae-Ds). Since theoretically the type of colony host affects parasitoid field performance, we conducted concatenated laboratory and field studies of both parasitoid lines. In the laboratory trials, T. drosophilae-Ds exhibited greater longevity, larger adult size, and higher fecundity than T. drosophilae-Dm. Both lines of parasitoids oviposited indistinctly in three drosophilid species commonly found in the berry zones of Colima: D. melanogaster, D. suzukii, and Zaprionus indianus Gupta. In the field trials, T. drosophilae-Ds had a larger population size and provided 2.4-fold higher pest reduction compared to T. drosophilae-Dm. Under the particular conditions of these field trials (berry fields separate from each other ≤ 3 km, and intensive agronomic management), these results demonstrate that T. drosophilae-Ds can significantly contribute more to the integrated management of D. suzukii than when reared on the commercial host D. melanogaster.

Chia Oil–Enriched Restructured Pork Effects on Oxidative and Inflammatory Status of Aged Rats Fed High Cholesterol/High Fat Diets

Jorge Arturo Santos-Lopez,Alba Garcimartın,Marıa Elvira Lopez-Oliva,Mirandeli Bautista-Avila,Marıa Jose Gonzalez-Munoz,Sara Bastida,Juana Benedı,Francisco Jose Sanchez-Muniz 한국식품영양과학회 2017 Journal of medicinal food Vol.20 No.5

Chia oil has the highest recognized α-linolenic acid (ALA) content. ALA is associated with beneficial changes in plasma lipids and the prevention of cardiovascular diseases. Present article aims to analyze the effect of Chia oil–enriched restructured pork (RP) on aged rats in a nonalcoholic steatohepatitis (NASH) model. Groups of six male Wistar rats (1-year old) were fed the experimental diets: control RP diet (C) noncholesterol high saturated; cholesterol-enriched high-saturated fat/high-cholesterol control RP diet (HC) with added cholesterol and cholic acid; and Chia oil- or Hydroxytyrosol RP cholesterol–enriched high-saturated fat/high cholesterol (CHIA and HxT). Total cholesterol, hepatosomatic index, Nrf2, antioxidant, and inflammation markers were determined. CHIA reduced the hypercholesterolemic effect by lowering levels similar to C; also, ameliorated redox index. CHIA, despite high polyunsaturated fatty acids (PUFA) content, reduced thiobarbituric acid reactive substances (TBARS) and induced the lowest SOD protein synthesis but not a reduction on its activity. Chia oil activated the Nrf2 to arrest the pro-oxidative response to cholesterol and aging. Endothelial nitric oxide synthase (eNOS) system was lower in HxT than in CHIA, suggesting its antiatherogenic activity and related protective effect against high PUFA. Increase in tumor necrosis factor alpha (TNFα) was partially blocked by CHIA. Chia oil has the ability to prevent oxidative damage and modify the inflammatory response, suggesting adequate regulation of the antioxidant system. Results stress the importance of incorporating ALA into the diet.

Airway management through submental derivation: a safe and easily reproduced alternative for patients with complex facial trauma

Gonzalez-Magana, Fernando,Malagon-Hidalgo, Hector Omar,Garcia-Cano, Eugenio,Vilchis-Lopez, Roberto,Fentanes-Vera, Adriana,Ayala-Ugalde, Fernan-Alejandra The Korean Association of Oral and Maxillofacial S 2018 대한구강악안면외과학회지 Vol.44 No.1

Objectives: Airway management in patients with panfacial trauma is complicated. In addition to involving facial lesions, such trauma compromises the airway, and the use of intermaxillary fixation makes it difficult to secure ventilation by usual approaches (nasotracheal or endotracheal intubation). Submental airway derivation is an alternative to tracheostomy and nasotracheal intubation, allowing a permeable airway with minimal complications in complex patients. Materials and Methods: This is a descriptive, retrospective study based on a review of medical records of all patients with facial trauma from January 2003 to May 2015. In total, 31 patients with complex factures requiring submental airway derivation were included. No complications such as bleeding, infection, vascular, glandular, or nervous lesions were presented in any of the patients. Results: The use of submental airway derivation is a simple, safe, and easy method to ensure airway management. Moreover, it allows an easier reconstruction. Conclusion: Based on these results, we concluded that, if the relevant steps are followed, the use of submental intubation in the treatment of patients with complex facial trauma is a safe and effective option.

Design of Two-Stage Class AB CMOS Buffers: A Systematic Approach

Antonio Lopez Martin,Jose Maria Algueta Algueta,Lucia Acosta,Jaime Ramirez-Angulo,Ramon Gonzalez Carvajal 한국전자통신연구원 2011 ETRI Journal Vol.33 No.3

A systematic approach for the design of two-stage class AB CMOS unity-gain buffers is proposed. It is based on the inclusion of a class AB operation to class A Miller amplifier topologies in unity-gain negative feedback by a simple technique that does not modify quiescent currents, supply requirements, noise performance, or static power. Three design examples are fabricated in a 0.5 μm CMOS process. Measurement results show slew rate improvement factors of approximately 100 for the class AB buffers versus their class A counterparts for the same quiescent power consumption (< 200 μW).

Prediabetes and Diabetes in Predominately Hispanic College Students

Juan Gonzalez,황인선,Jung-Il Oh,Alayna Mora,Alondra Lopez,이광용 한국웰니스학회 2023 한국웰니스학회지 Vol.18 No.3

Due to the high rate of adult-onset type 2 diabetes in South Texas, the purpose of this study was to investigate the prevalence of prediabetes and diabetes among college age students 18-30 years old between colleges at a predominantly Hispanic institution. De-identified blood biomarker data was quantitatively analyzed and compared with the American Diabetes Association(ADA) prediabetes and diabetes 2015 criteria. The significance of this research targets a young population where early intervention would be most effective. De-identified blood biomarkers such as fasting glucose levels and hemoglobin HgA1c levels, along with BMI were analyzed. These results were organized by genders and colleges across campus. This research was reviewed and approved by the university Institutional Review Board. Results for males(n=68) measured fasting glucose (96.25±27.52mg/dL), HgA1c levels(5.772±1.050%), as well as BMI(32.41±9.302). Data for females(n=152) measured fasting glucose(92.56±27.23mg/dL), HgA1c(5.744±0.922%), and BMI (32.72±9.060). Students across genders and colleges on campus at a predominantly Hispanic institution were below the blood biomarker levels that define diabetes. However, students are at risk for prediabetes according to the 2015 ADA prediabetes HgA1c criteria. Results indicated that 5 out of the 7 colleges on campus were prediabetic according to the HgA1c levels reported. This is a significant finding and suggests that an early surveillance mechanism is recommended for the Hispanic college age population in South Texas.

Therapeutic effect of the immunomodulatory drug lenalidomide, but not pomalidomide, in experimental models of rheumatoid arthritis and inflammatory bowel disease

Belen Lopez-Millan,Rafael Diaz de la Guardia,Heleia Roca-Ho,Carmen M García-Herrero,Jessie R Lavoie,Michael Rosu-Myles,Elena Gonzalez-Rey,Francisco O’Valle,Gabriel Criado,Mario Delgado,Pablo Menendez 생화학분자생물학회 2017 Experimental and molecular medicine Vol.49 No.-

Thalidomide is an immunomodulatory drug (IMiD) with proven therapeutic action in several autoimmune/inflammatory diseases; however, its inherent high toxicity has led to the development of more powerful and safer thalidomide analogs, including lenalidomide and pomalidomide. These are new generation IMiDs that exhibit direct antitumor activity as well as anti-inflammatory/immunomodulatory properties, and are FDA-approved for the treatment of several hematological malignances. Here we investigated the potential therapeutic effects of lenalidomide and pomalidomide in several experimental murine models of autoimmune/inflammatory diseases: 2,4,6-trinitrobenzene sulfonic acid- and dextran sulfate sodium-induced inflammatory bowel disease and type II collagen-induced arthritis. Lenalidomide displayed a strong therapeutic effect in all these models of autoimmune/inflammatory diseases, while the effect of pomalidomide was less pronounced. In vitro experiments confirmed the immunosuppressive effect of both IMiDs on the proliferative response of stimulated human lymphocytes and on the balance of secreted cytokines toward an anti-inflammatory profile. We conclude that lenalidomide may offer a therapeutic opportunity against autoimmune/inflammatory diseases.

Acupuncture Points and Their Relationship with Multireceptive Fields of Neurons

Salvador Quiroz-Gonzalez,Sergio Torres-Castillo,Rosa Estela Lopez-Gomez,Ismael Jimenez Estrada 사단법인약침학회 2017 Journal of Acupuncture & Meridian Studies Vol.10 No.2

In Traditional Chinese Medicine, acupuncture points (APs) have been emphasized as key elements that generate the therapeutic effects of acupuncture. At the spinal cord or supraspinal level, sensory neurons located in the dorsal horn receive an extensive supply of sensory information from skin and muscle receptors through peripheral afferent nerves. The stimulated skin area that influences the activity of a spinal sensory neuron is known as the peripheral receptive field (RF) of that neuron. By considering that a particular AP location involves the activation of one or various RFs, it can be assumed that several sensory central neurons are the site of convergence of the peripheral input generated by acupuncture stimulation. However, stimulation on nonacupoint sites could also activate skin areas with RFs that have been sensitized, and they could be involved in the generation of nonspecific effects of acupuncture, as seen in clinical practice. From the latter, it is suggested that effective APs, and even nonacupoints, are associated with a particular arrangement of RFs, and their study will be useful for understanding the intrinsic mechanisms of acupuncture and for the development and identification of more efficient sites and modes of acupuncture stimulation to evoke optimal therapeutic actions.

Characterization and evaluation of liver fibrosis grade in patients with chronic hepatitis B virus infection and normal transaminases

( San Juan Lopez Cristina ),( Casado Martin Marta ),( Gonzalez Sanchez Mercedes ),( Porcel Martin Almudena ),( Hernandez Martinez Alvaro ),( Vega Saenz Jose Luis ),( Parron Carreno Tesifon ) 대한간학회 2018 Clinical and Molecular Hepatology(대한간학회지) Vol.24 No.4

Backgrounds/Aims: The objective of our study was to determine the epidemiological, laboratory, and serological characteristics of patients with chronic hepatitis B virus (HBV) infection and normal transaminases. The study also aimed to evaluate liver damage by measuring the liver fibrosis (LF) grade and to identify possible factors associated with the presence of fibrosis. Methods: A retrospective observational study was conducted in patients with chronic HBV infection and classified as inactive carriers or immune-tolerant. Epidemiological variables of age, sex, immigrant, alcohol consumption, and body mass index (BMI), as well as virological variables (HBV DNA) and transaminase level were collected throughout the follow-up. The LF grade was evaluated by transient elastography. The cutoff value for significant fibrosis (SF) was liver stiffness ≥7.9 kPa. Results: A total of 214 patients were included in the analysis, and 62% of them had a BMI ≥25 kg/㎡. During follow-up, 4% of patients showed transaminase elevation (<1.5 times normal). Most patients had a viral DNA level <2,000 IU/mL (83%). Data on LF were available in 160 patients; of these, 14% had SF, 9% F3, and 6% F4. The variables associated with the presence of SF were transaminase alteration during follow-up, as 23% of patients with SF had elevated transaminases versus 3% of patients without SF (P<0.005), and BMI, as the vast majority of patients with SF (88%) had a BMI ≥25 kg/㎡ versus 56% of patients without SF (P<0.05). Conclusions: In patients with chronic HBV infection and normal transaminases, liver damage does not seem to be related to DNA levels, alcohol consumption, or immigrant status. SF seems to be associated with transaminase alteration during follow-up and elevated BMI. It is therefore recommended to measure LF grade with validated non-invasive methods in such patients. (Clin Mol Hepatol 2018;24:384-391)

Effect of Ursolic Acid on Insulin Resistance and Hyperinsulinemia in Rats with Diet-Induced Obesity: Role of Adipokines Expression

Angelica S. Gonzalez-Garibay,Alfonso Lopez-Vazquez,Jesus Garcıa-Banuelos,Sergio Sanchez-Enrıquez,Ana S. Sandoval-Rodrıguez,Susana Del Toro Arreola,Miriam R. Bueno-Topete,Jose F. Munoz-Valle,Mercedes E 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.3

Excess of visceral adipose tissue (VAT) characteristic of obesity leads to a proinflammatory state disrupting the insulin signaling pathway, triggering insulin resistance (IR) and inflammation, the main processes contributing to obesity comorbidities. Ursolic acid (UA), a pentacyclic triterpenoid occurring in a variety of plant foods, exhibits anti-inflammatory properties. The aim of this study was to evaluate UA effects on IR, hyperinsulinemia, and inflammation in experimental diet-induced obesity. Forty male Wistar rats were randomly assigned to eight groups (n = 5). One group was used for time 0. Three groups were labeled as OBE (control): receiving high-fat diet (HFD; fat content 45.24% of energy) during 3, 6, or 9 weeks; three groups UA-PREV: exposed to simultaneous HFD and UA during 3, 6, or 9 weeks to evaluate UA preventive effects; one group UA-REV: receiving HFD for 6 weeks, followed by simultaneous HFD and UA for three additional weeks to analyze UA reversal effects. Measurements were performed after 3, 6, or 9 weeks of treatment. Adiposity was calculated by weighing VAT after sacrifice. Serum markers were quantified through colorimetric and enzyme-linked immunosorbent assay methods. VAT adipokines RNAm expression was evaluated by quantitative reverse transcriptase–polymerase chain reaction. Data were analyzed by Kruskal–Wallis and Mann–Whitney U tests. UA significantly decreased adiposity, IR, hyperinsulinemia, triacylglycerides, and cholesterol levels, and also VAT mRNA expression of MCP-1 (monocyte chemoattractant protein-1), IL (interleukin)-1β and IL-6, concomitantly increasing adiponectin levels. UA metabolic effects demonstrated in this study support its potential therapeutic utility to improve IR, hyperinsulinemia, and inflammation observed in obesity and diabetes.

A systematic review of the accuracy and efficiency of dental movements with Invisalign®

Lidia Galan-Lopez,Jorge Barcia-Gonzalez,Eliseo Plasencia 대한치과교정학회 2019 대한치과교정학회지 Vol.49 No.3

We are currently living in an era where the use of computer-aided design/ computer-aided manufacturing has allowed individualized orthodontic treatments, but has also incorporated enhanced digitalized technology that does not permit improvisation. The purpose of this systematic review was to analyze publications that assessed the accuracy and efficiency of the Invisalign® system. A systematic review was performed using a search strategy to identify articles that referenced Invisalign®, which were published between August 2007 and August 2017, and listed in the following databases: MEDLINE, Embase, Cochrane Library, Web of Knowledge, Google Scholar, and LILACS. Additionally, a manual search of clinical trials was performed in scientific journals and other databases. To rate the methodological quality of the articles, a grading system described by the Swedish Council on Technology Assessment in Health Care was used, in combination with the Cochrane tool for risk of bias assessment. We selected 20 articles that met the inclusion criteria and excluded 5 due to excess biases. The level of evidence was high. Although it is possible to treat malocclusions with plastic systems, the results are not as accurate as those achieved by treatment with fixed appliances.