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Hydraulic Force and Impeller Evaluation of a Centrifugal Heart Pump
Timms, D.L,Tan, A.C.C,Pearcy, M-J,Mcneil, K,Galbraith, A The Korean Society of Marine Engineering 2004 한국마린엔지니어링학회지 Vol.28 No.2
A rig was constructed to test the performance characteristics and compare the hydraulic forces exerted on a centrifugal type artificial heart impeller. A conventional shaft. seal and bearing system. while driven by a small electric motor. supported the impeller which was separated from the pump casing by a six degree of freedom force transducer (JR3 Ine). Radial (x. y) and axial (z) hydraulic forces were recorded and compared. At physiological operating conditions. the results indicate that the double entry/exit centrifugal pump encounters a smaller radial force and significantly reduced axial thrust. These experimental results are valuable in the design of a magnetic bearing system to suspend the impeller of a centrifugal artificial heart pump. This experimental technique may also be applied to evaluate the required capacity and predict the lifetime of contact bearings in marine pumps.
Experimental Flow Visualisation of an Artificial Heart Pump
Tan, A.C.C.,Timms, D.L.,Pearcy, M.J.,McNeil, K.,Galbraith, A. The Korean Society of Marine Engineering 2004 한국마린엔지니어링학회지 Vol.28 No.2
Flow visualization techniques were employed to qualitatively visualize the flow patterns through a 400% scaled up centrifugal blood pump. The apparatus comprised of a scaled up centrifugal pump. high speed video camera. Argon Ion Laser Light Sheet and custom coded particle tracking software. Reynolds similarity laws are applied in order to reduce the rotational speed of the pump. The outlet (cutwater) region was identified as a site of high turbulence and thus a likely source of haemolysis. The region underneath the impeller was identified as a region of lower flow.
Lee, Tae-Ho,Kim, Yeon-Ki,Pham, Thu Thi Minh,Song, Sang Ik,Kim, Ju-Kon,Kang, Kyu Young,An, Gynheung,Jung, Ki-Hong,Galbraith, David W,Kim, Minkyun,Yoon, Ung-Han,Nahm, Baek Hie American Society of Plant Physiologists 2009 PLANT PHYSIOLOGY - Vol.151 No.1
<P>Microarray data can be used to derive understanding of the relationships between the genes involved in various biological systems of an organism, given the availability of databases of gene expression measurements from the complete spectrum of experimental conditions and materials. However, there have been no reports, to date, of such a database being constructed for rice (Oryza sativa). Here, we describe the construction of such a database, called RiceArrayNet (RAN; http://www.ggbio.com/arraynet/), which provides information on coexpression between genes in terms of correlation coefficients (r values). The average number of coexpressed genes is 214, with sd of 440 at r >or= 0.5. Given the correlation between genes in a gene pair, the degrees of closeness between genes can be visualized in a relational tree and a relational network. The distribution of correlated genes according to degree of stringency shows how each gene is related to other genes. As an application of RAN, the 16-member L7Ae ribosomal protein family was explored for coexpressed genes and gene expression values within and between rice and Arabidopsis (Arabidopsis thaliana), and common and unique features in coexpression partners and expression patterns were observed for these family members. We observed a correlation pattern between Os01g0968800, a drought-responsive element-binding transcription factor, Os02g0790500, a trehalose-6-phosphate synthase, and Os06g0219500, a small heat shock factor, reflecting the fact that genes responding to the same biological stresses are regulated together. The RAN database can be used as a tool to gain insight into a particular gene by examining its coexpression partners.</P>