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- 저자 : Farshid Bastami (검색결과 3 건)
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Majid Salehi,Arian Ehtrami,Farshid Bastami,Saeed Farzamfar,Sepanta Hosseinpour,Hamid Vahedi,Ahmad Vaez,Mostafa Rahvar,Arash Goodarzi 한국섬유공학회 2019 Fibers and polymers Vol.20 No.3
Peripheral nerve injury is a serious challenge which influences 2.8 percent of trauma patients. Tissue engineeringof peripheral nerves mainly focuses on axonal regeneration via various nerve guides. The aim of this study is to evaluate a novel polyurethane (PU)/gelatin nanofibers (GNFs) conduit’s potential combination with resveratrol (RVT) for sciatic nerve regeneration in the rat. Platelet-rich plasma (PRP) was used as a carrier for RVT. Different tests like contact angle, tensile strength etc. was used to evaluate properties of PU/GNFs conduits. In addition, the electron microscopy, MTT assay, and DAPI staining revealed its compatibility with Schwann cells. 24 male Wistar rats were allocated into four groups (n=6) (1) PU/GNF/PRP/Schwann cell, 2) PU/GNF/Schwann cell/PRP/RVT, 3) Positive control, and 4) Negative control in order to assess sciatic functional index (SFI), hot plate latency, electromyographical (EMG), the percentage of wet weight-loss of gastrocnemius muscle and histopathological studies using hematoxylin-eosin staining. The results represented sciatic functional index (SFI), hot plate latency, electromyographical improved significantly in group 1 and 2 compared to the negative control group. Histopathological findings showed remarkable improvements in myelin sheath regeneration and fibers condition in group 1 and 2 compared to the negative control group. Group 2 showed more resemblance to the normal sciatic nerve, with well-arranged fibers and an intact myelin sheath. This study successfully applied PU/GNFs/PRP/RVT conduits as a potential biocompatible nerve guide with proper mechanical properties, biocompatibility, and biodegradability that enhanced injured sciatic nerve’s recovery rate.
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Reza Tabrizi,Kousha Bakrani,Farshid Bastami 대한구강악안면외과학회 2019 대한구강악안면외과학회지 Vol.45 No.4
Objectives: Postoperative paresthesia is a common complication after sagittal split osteotomy (SSO). This study aimed to compare paresthesia among different fixation methods one year postoperative. Materials and Methods: This prospective cohort study assessed subjects in four groups: class II with miniplate fixation (Group 1), class II with three-screw fixation (Group 2), class III with miniplate fixation (Group 3), and class III with three-screw fixation (Group 4). Paresthesia was evaluated one year postoperative based on a 0-10 visual analogue scale. Pearson correlation was used to evaluate associations of age and mandibular movement with paresthesia. ANOVA was used to compare paresthesia among groups. Results: A total of 80 subjects were enrolled, with 20 subjects in each of the four groups. The Pearson correlation test demonstrated a significant correlation between mandibular movement and paresthesia (P=0.001). Comparison of paresthesia among the groups showed significant differences among groups 1 and 2, 2 and 3, and 3 and 4 (P<0.05). Conclusion: The three-screw fixation method led to more paresthesia one year postoperative compared with miniplate fixation. In addition, the magnitude of mandibular movement had a positive correlation with paresthesia.
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Maryam Mojahedian,Farahnaz Fahimipour,Kim Lambertsen Larsen,Mahdi Kalantar,Farshid Bastami,Negin Omatali 한양대학교 세라믹연구소 2016 Journal of Ceramic Processing Research Vol.17 No.11
One of the easy ways to prepare nanocrystalline hydroxyapatite (nano-HAp) is the sol-gel method that due to its uniqueadvantages compared to conventional methods, has raised research interest among scientists. The purpose of this study wasto investigate the properties of nano-HAp powders which were synthesized by ethanol-based sol-gel method withstoichiometric ratio of Ca/P = 1.67 and comparing it with closer ratios of 1.5 and 1.6. To do so, we used the aqueous solutionof phosphorus pentoxide (p205, MERCK) and four-watered calcium nitrate (Ca (NO3)2.4H2O, MERCK) in ethanol. Theresulted nano-powders and sintered pellets made of it were analysed and compared with X-ray diffraction analysis (XRD). Also, the sintered pellets’ bioactivity in simulated body fluid (SBF) solution was examined by SEM. In powders which werecalcined at the temperature of 600 oC, the most amorphous phase (49%) in comparison to Ca/P = 1.5 was observed. Aftersintering, the main phase of 1.67 ratio was hydroxyapatite (HAp) and the main phase of 1.5 ration was β-TCP, although in1.6 ration a composite of HAp and β-TCP was observed. According to the results, sol-gel method for producing nanocrystallineHAp was an appropriate method; in addition, compared with the different ratios of Ca/P, the stoichiometric nanocrystallinemay have better bioactivity.
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