http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Faiza Mouderas,Imad Abdelhamid El Haci,Farid Boucif Lahfa 경희대학교 융합한의과학연구소 2019 Oriental Pharmacy and Experimental Medicine Vol.19 No.3
The aim of this study was to investigate for the frst time the antioxidant and the antimicrobial activities of organic extracts from Traganum nudatum Delile using in vitro models. The extracts which exhibited the highest activities were then submitted to RP-HPLC–PDA analysis. The phytochemical screening revealed the presence of favonoids, tannins, alkaloids, saponins and quinones. The highest amounts of polyphenols, favonoids and favonols were recorded in ethyl acetate fractions. The strongest DPPH scavenging ability was attributed to ethyl acetate fraction of crude extract prepared by maceration EAFM with IC50 value of 20±0.11 µg/mL, ethyl acetate fraction of crude extract prepared by infusion EAFI was found to possess the highest ferric reducing power with EC50 of 35±0.4 µg/mL. The highest antioxidant capacity 200.21±0.2 mg AAE/g was exhibited by n-butanol fraction of crude extract prepared by maceration BFM. The antimicrobial activity was proven against all the tested microorganisms except on Candida albicans strains. The extracts were more active on Gram positive than Gram negative bacteria. The strongest inhibition was provided against Bacillus subtilis, Bacillus cereus and Listeria monocytogenes. The identifcation of phenolic compounds using RP-HPLC–PDA technique revealed the presence of sinapic, syringic, ferulic, p-coumaric acids, catechin, naringenin and vanillin that may be responsible for the bioactivities of the reported specie. Our results indicate that T. nudatum Delile may provide a rich and novel source of natural antioxidants for industrial utilization replacing synthetic ones.