최단거리를 이용한 요검사 자동화

차은종, 김경아 충북대학교 의과대학 충북대학교 의학연구소 2012 忠北醫大學術誌 Vol.22 No.1

연구목적: 최단거리를 이용한 요검사 자동분별 기술을 개발하여 그 유용성을 실험적으로 검증하고자 하였다. 대상 및 방법: 요성분 비색표 검사시 사용하는 검사지와 표준비색표의 색을 자동 분별하기 위한 5가 지 색 구성요소 및 기하학적 최단거리를 도입하였다. 요검사를 수행한 검사지의 색 구성요소들을 산출 하여 5차원 공간상의 한 점에 대응시키고 표준비색표와의 거리를 비교함으로써 가장 유사한 색을 선별 하였다. 동일 비색표 차트 간 색 구성요소의 절대오차를 비교하였으며, 예비실험으로서 피검자 5인에 대해 자동분별기법을 실시하여 육안검사 결과와 비교하였다. 결과: 동일 비색표 차트간 색 구성요소의 절대오차는 0~5 범위에 분포하였으며, 약 94%가 0~2의 값을 나타냈다. 피검자 5인을 대상으로 총 10개의 검사항목에 대해 자동분별기법을 적용하였으며, 그 결과는 육안판정 결과와 100% 일치하였다. 결론: 기하학적 최단거리 기법을 도입하여 요성분 비색표 검사를 자동화하였으며, 기존 검사기기의 판 정 일치율보다 약 2배 이상 정확한 판정이 가능함을 실험적으로 검증하였다.

수중 호흡 측정 센서

차은종, 손호선, 김경옥, 김경아 충북대학교 의과대학 충북대학교 의학연구소 2016 忠北醫大學術誌 Vol.26 No.2

본문참고

납, 수은 및 유기용제 폭로근로자들의 조기 신장 손상 지표인 요중 N-Acetyl-β-Glucosaminidase activity에 관한 조사연구

차철환,김광종,이은일 大韓産業醫學會 1993 대한직업환경의학회지 Vol.5 No.1

The urinary N-Acetyl-β-Glucosaminidase activity test has been recommended as sensitive method to detect early renal dysfunction by many toxic chemicals. To catch the high reference value of urinary N-Acetyl-β-Glucosaminidase activity in Korean, the total of 108 reference workers exposed only to noise were surveyed. And N-Acetyl-β-Glucosaminidase activities in 42 mercury workers at a fluorescent lamp manufacturing factory and 50 reference workers were measured to detect early renal dysfunction of mercury workers. The total of 27 mercury workers were followed 1 year to examine change of the N-Acetyl-β-Glucosaminidase activities according to the change of urinary mercury level. It was also examined to the N-Acetyl-β-Glucosaminidase activities of 8 lead exposed workers and 44 carbon disulfide exposed workers. It was examined to the correlation coefficients between the N-Acetyl-β-Glucosaminidase activities and total protein, β-1-microglobulin, β-2-microglobulin in 24 hour urine in 42 carbon disulfide exposed workers and 14 medical students as refernce group. And the correlation coeffecients between the N-Acetyl-β-Glucosaminidase activities in 24 hour urines and in spot urines were measured in 12 lead exposed workers and 43 mercury exposed workers. The results were as follows; 1. The high reference value of urinary N-Acetyl-β-Glucosaminidase activities in Korean was 180 nanomole methylumbellyferon/mg creatine of urine. 2. The correlation coefficients of N-Acetyl-β-Glucosaminidase activities and microalbumin, α-1-microglobulin, β-2-microglobulin in 24 hour urine were about 0.5 respectively. 3. The values of N-Acetyl-β-Glucosaminidase activities of spot urines in mercury exposed workers were statistically significant higher than those in reference group. and about 76.5% of workers of whom the urinary mercury level decreased after 1 year follow-up, also decreased the values of N-Acetyl-β-Glucosaminudase activities of spot urines. 4. There was no significant correlation between the N-Acetyl-β-Glucosaminidase activity of spot urines and blood lead level in lead exposed workers. But a half of workers have increased N-Acetyl-β-Glucosaminidase activities above the reference level. 5. The values of N-Acetyl-β-Glucosaminidase activities of spot urines in carbon disulfide exposed workers were statistically significantly higher than those in reference group. And for workers exposed to carbon disulfide and having retinopathy, the meanvalues of the N-Acetyl-β-Glucosaminidase activities were significantly higher, as compared to those having normal retina. 6. the correlation coefficients of N-Acetyl-β-Glucosaminidase activities between the values of 24 hour urines and those of spot urine were 0.76 in carbon disulfide exposed workers, 0.5 in lead exposed workers, 0.4 in mercury exposed workers, respectively. Among the correlation coefficients between the values of first morning urine samples and those of 24 hour urine samples were highest.

형광등제조사업장 수은폭로근로자들의 요중 N-Acetyl-β-Glucosaminidase activity에 관한 연구

李恩一,車喆煥,金鍾源 고려대학교 의과대학 1991 고려대 의대 잡지 Vol.28 No.1

The periodic evaluation of workers exposed to mercury has some limitations in detectin early changes of renal dysfunction with existing methods of blood or urine examination because of low sensitvivity. The urinary N-acetyl-β-glucosaminidase(NAG) activity test has been recommended as sensitive method to detect early renal dysfunction by many foreign researchers. So urinary NAG activitiy in urine of workers who were exposed to mercury at a fluorescent lamp manufacturing factory was determined to study early renal dysfunction of the workers. Fifty textile workers and six healthy members of a research institute served as reference subjects. The results were as follows : 1. The correlation between urinary NAG and mercury was statistically significant(p(0.001), and the correlation coefficient was 0.4449. 2. The high reference value of urinary NAG activity in reference subjects was 360μMole methyluMbelliferone /mg of creatinine. 3. When the mercury levels in urine were grouped as under 50μg /1, 50-300μg /1 and aboVe 300μg /1, the percentage of test subjects whose urinary NAG activities were greater than the high reference value(370μmole methylumbelliferone/mg of creatinine) were 9.5%, 40.9% and 57.1%, respectively. However, this increasing trend was not statistically significant when the test subjects were limited only to the group exposed to mercury(30.8%-40.9%-57.1%, p=0.52) . 4. About 43% of subjects whose urinary mercury were above 300μg /1 had urinary NAG actiVity below 360MU μM /mg Cret. This result suggests that urinary mercury level is not a absolute indicator in diagnosis of mercury poisoning and a sensitive method which can detect the early health effects of mercury need to be developed.

건축벽체용 광택문양콘크리트의 성능평가에 관한 실험적 연구

김종원,김재은,차광석,조상영,정재욱,정상진 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

Contemporary, architecture calls for a wide range of surface textures and treatments. A surface compatible with the architecture's design may vary from a glass-smooth finish to one requiring special sculptured ornamentation. These surfaces require many different types of form sheathing and lining. The purpose of study development new design form and made elaborateness shape. Easy to used in field that architecture finish material not used expect effective reduce of working hours, personnel expenses, architecture finish material, cost, through this study, we have figured out the best mix proportion for durability and gloss ability of glossing exposure concrete.

Wafer final polishing에 따른 표면 현상과 마멸도에 관한 연구

원종구,이정택,황성철,차지완,이은상 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

In recent years, developments in the semiconductor and electronic industries have brought a rapid increase in the use of silicon wafer. For further improvement of the ultra precision surface and flatness of Si wafer necessary to high density ULSI, it is known that final polishing is very important. Polishing one of the important methods in manufacturing of Si wafers and in thinning of completed device wafers. This study will report the evaluation on abrasion of wafer according to variety processing condition, which have major influence on the abrasion and surface defect of Si wafer polishing, were adapted to polishing pressure, machining speed, and the slurry mix ratio. Thus the optimum condition selection of ultra precision Si wafer polishing using load cell and infrared temperature sensor. To evaluate each machining factor, use a data through each sensor. That evaluation of abrasion according to variety condition is selected to use a result data that measure a pressure, machining speed, and the processing time. And optimum condition is selected by this result. By using optimum condition, it achieve a ultra precision mirror like surface.

스트레스 측정도구의 표준화 방안

장세진,차봉석,박종구,이은경 연세대학교 원주의과대학 1994 원주의대논문집 Vol.7 No.1

3차원 초음파로 산전진단된 흉결합 쌍태아 1예

전규정,이은혜,차선희 대한산부인과초음파학회 2000 대한산부인과초음파학회지 Vol.2 No.2

국내산 무화과를 이용한 와인 제조 및 품질 개선 효과

정미란,차정단,윤순일,한종현,이영은 동아시아식생활학회 2005 동아시아식생활학회지 Vol.15 No.1

Fig(Ficus carica L.) which belongs to Moraceae family has been used as digestion promoter, cure for ulcerative inflammation and eruption in Korea. Figs have very short preservation period and can be kept only 1 week even in the refrigeration system. The possibility of wine-making from Korean figs was tested by analyzing the fermentation characteristics, proximate analysis and free sugar contents of wine made of slices with 20% sugar addition. Ethanol fermentation of the figs by Saccharomyces cerevisiae was done rapidly. The ethanol contents, pH, total acidity and sugar content were 12.1%, 3.91, 0.42% and 9.9 °Brix, respectively. The results from the sensory evaluation were as follows. The wine made from the sliced figs were better than that from fig juices in their sensory scores. The wine made with frozen figs was not different from that made with fresh ones. To improve the quality of wine, the addition of dried leaf powder in the concentration of 100 ppm were tried and found it was superior to the one made without leaf.

PC를 이용한 소아과 퇴원환자 관리시스템

하태선,이태수,차은종,박범수,한헌석,채수일 충북대학교 의과대학 충북대학교 의학연구소 1993 忠北醫大學術誌 Vol.3 No.1

본원 소아과 입원환자의 퇴원요약 기록을 전산관리하는 시스템을 개발하였다. 소아과 환자관리에 적합하도록 퇴원요약지를 설계하였고 개인용 컴퓨터를 사용하여 관리하도록 구성하였다. 주 기억장치 4MB와 보조기억 장치 120MB HDD을 장착한 PC-386DX 시스템을 기반으로 개발하였고 소프트웨어로는 FoxPro v2.0을 사용하였다. pull-down menu 방식과 window방식을 적용하여 비전문가라 할지라도 손쉽게 사용할수 있도록 하였고 정보입력 및 수정시 사용자 편의를 최대한 반영하고자 하였다. "AND"와 "OR"연산자를 사용하여 다양한 검색이 가능하였다. 본 시스템은 현재 본원 소아과에서 실무에 적용하고 있으며 향후 통계분석과 임상연구에 크게 활용할 수 있으리라 생각된다. A PC-based system was developded to manage discharge summary records of pediatric patients. It is based on a PC-386DX system equipped with 4MB memory and 120MB HDD, and its software was written in FOXPRO V2.0. Any users unfamiliar with computer can make an easy access to the data through pull-down menu and windows system. Logical operators of "AND" and/or "OR" enabled a flexible and various search conditions. The present system is being under clinical use in the Department of Pediatrics, and warrants future applications to statistical analysis as well as clinical research projects.