Effects of Replacement of Soybean Meal by Cottonseed Meal on Laying Performance and Haemoglobin Levels in Practical Diets for Breeder Japanese Quail, Coturnix coturnix japonica

Erturk, M. Mustafa,Ozen , Nihat,Celik, Kemal Asian Australasian Association of Animal Productio 2004 Animal Bioscience Vol.17 No.7

A 16 week feeding trial was conducted to evaluate the effects of replacement of soybean meal (SM) by extracted cottonseed meal (CSM) on laying performance and haemoglobin levels in practical diets for breeder Japanese quail (Coturnix coturnix japonica). One hundred ninety two quails (6 weeks old) were divided randomly into eight groups. The diets were isocaloric containing 2,900 kcal/kg of ME and isonitrogenous (% 20 crude protein) as fed basis. SM was replaced by 0, 2.5, 5.0, 7.5, 10.0, 12.5, 15.0 and 17.5% of CSM, respectively. Average egg production (quail day, %; quail house, %), egg weight (g), daily feed intake (g/bird), feed efficiency ratio (g feed/g egg) data indicated no significant differences among the treatments; while, blood haemoglobin levels (% g Hb) of 7th (15.0% CSM) and 8th (17.5% CSM) group were lower than the control (0% CSM) diet (p<0.05). This experiment indicated that 17.5% CSM could replace SM (providing 44% of SM protein) in practical diets of breeder Japanese quails without any significant impairment on laying performance.

Evaluation of Genetic Variations in miRNA-Binding Sites of BRCA1 and BRCA2 Genes as Risk Factors for the Development of Early-Onset and/or Familial Breast Cancer

Erturk, Elif,Cecener, Gulsah,Polatkan, Volkan,Gokgoz, Sehsuvar,Egeli, Unal,Tunca, Berrin,Tezcan, Gulcin,Demirdogen, Elif,Ak, Secil,Tasdelen, Ismet Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.19

Although genetic markers identifying women at an increased risk of developing breast cancer exist, the majority of inherited risk factors remain elusive. Mutations in the BRCA1/BRCA2 gene confer a substantial increase in breast cancer risk, yet routine clinical genetic screening is limited to the coding regions and intronexon boundaries, precluding the identification of mutations in noncoding and untranslated regions. Because 3' untranslated region (3'UTR) polymorphisms disrupting microRNA (miRNA) binding can be functional and can act as genetic markers of cancer risk, we aimed to determine genetic variation in the 3'UTR of BRCA1/BRCA2 in familial and early-onset breast cancer patients with and without mutations in the coding regions of BRCA1/BRCA2 and to identify specific 3'UTR variants that may be risk factors for cancer development. The 3'UTRs of the BRCA1 and BRCA2 genes were screened by heteroduplex analysis and DNA sequencing in 100 patients from 46 BRCA1/2 families, 54 non-BRCA1/2 families, and 47 geographically matched controls. Two polymorphisms were identified. SNPs $c.^*1287C$ >T (rs12516) (BRCA1) and $c.^*105A$ >C (rs15869) (BRCA2) were identified in 27% and 24% of patients, respectively. These 2 variants were also identified in controls with no family history of cancer (23.4% and 23.4%, respectively). In comparison to variations in the 3'UTR region of the BRCA1/2 genes and the BRCA1/2 mutational status in patients, there was a statistically significant relationship between the BRCA1 gene polymorphism $c.^*1287C$ >T (rs12516) and BRCA1 mutations (p=0.035) by Fisher's Exact Test. SNP $c.^*1287C$ >T (rs12516) of the BRCA1 gene may have potential use as a genetic marker of an increased risk of developing breast cancer and likely represents a non-coding sequence variation in BRCA1 that impacts BRCA1 function and leads to increased early-onset and/or familial breast cancer risk in the Turkish population.

Effects of Replacement of Fish Meal with Poultry By-product Meals on Apparent Digestibility, Body Composition and Protein Efficiency Ratio in a Practical Diets for Rainbow Trout, Onchorynchus mykiss

Erturk, M.Mustafa,Sevgili, Huseyin Asian Australasian Association of Animal Productio 2003 Animal Bioscience Vol.16 No.9

This study examined the replacement of the fish meal (FM) with commercial poultry by-product meal (PBM) in practical diets for rainbow trout (Onchorynchus mykiss, Walbaum). Five isocaloric and isonitrogenous diets containing levels 0 (control), 10, 20, 30 and 40% of PBM as a replacement for FM were fed to three replicate groups of rainbow trout with a initial weight $34.50{\pm}0.43g$ (mean${\pm}$SE). Protein efficiency ratio (PER) of diets containing PBM up to 20% were similar to the control while significantly lower values were obtained from the groups receiving higher levels of PBM (p<0.05). Apparent protein digestibility coefficients (ADCs) were significantly lower than that of the control group when PBM was included at level of 20% or more. Similarly, significantly lower values were observed with diets containing 30 and 40% PBM in terms of dry matter, organic matter, ether extract, ash and energy digestibility (p<0.05). Dietary treatments did not significantly affect the body composition of the fish in terms of dry matter, crude protein, ether extract and ash. In conclusion, PBM in a proportion of 20% may replace about 40 % of FM in rainbow trout diet without significant impairment grow.

Slide Session : OS-END-26 ; Endocrinology : Vitamin D Levels in Patients with Autoimmune Thyroid Disease

( Esref Erturk ),( Meral Mert ),( Yildiz Okuturlar ),( Ozlem Soyluk ),( Pinar Karakaya ),( Ozlem Harmankaya ),( Abaki Kumbasar ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: It is known that vitamin D has effects on the immune system. Vitamin D is an important immune system regulator. Several observational studies show that, vitamin D inhibits proinflammatory processes by suppressing the enhanced activity of immune cells that take part in the autoimmune reaction. It has been suggested that vitamin D may play a role in the pathogenesis of several endocrine diseases, such as autoimmune thyroid diseases, hyperparathyroidism, diabetes mellitus, Addison`s disease. In this study it is aimed to find a correlation between autoimmune thyroid disease and vitamin D. Methods: Thyroid function test result, calcium, PTH and vitamin D levels were compared between a control group of 35 healthy people and 35 patients with a cross-sectional thyroid autoimmune disease. Results: Mean ages are found to be 41.8±14.08 years and 45.6±13.46 years in patients and controls respectively. Mean vitamin D, calcium and parathormone (PTH) levels in patients and control group are found to be 18.6±9.5 vs 39.13 ±14.6 ng/ml, 7.9±0.16 vs 8.67±0.80 mg/dl, 50.7±25.86 vs 56.21±18.17 pg/ml, respectively. Vitamin D levels were found to be significantly lower than the control group in patients with autoimmune thyroid disease. There was no difference between the levels of PTH. Conclusions: Analyzing of vitamin D, PTH and calcium parameters should be considered in patients with autoimmune thyroid diseases. Treatment of vitamin D deficiency may help increase the quality of life in tyroid patients.

Effect of the Pruritus on the Quality of Life: A Preliminary Study

( Irem Eren Erturk ),( Ozer Arican ),( Imran Kurt Omurlu ),( Necdet Sut ) 대한피부과학회 2012 Annals of Dermatology Vol.24 No.4

Background: Pruritus affects the quality of life (QoL) in the patients. However, little is known of the impacts of itching on the QoL in the literature. Objective: In this study, a questionnaire eliciting specific responses about pruritus was used to determine the effect of itching and its severity on QoL in chronic pruritic patients. Methods: One hundred ten adult patients with chronic pruritus were surveyed. Once itch severity had been self-reported by patients, together with Skindex-29, they have been given the 18-item Pruritus- related Life Quality Index (PLQI) questionnaire, which was used to generated the new index. Results: Significant correlations have been found between the pruritus severity score of participants and their total Skindex-29 (p<0.001) with its function, emotion and symptom subscale scores (p <0.001 for each). Also, significant correlations were evident between total PLQI (p<0.001) and its psychosocial negativities, difficulties in everyday activities and social live subscale scores (p<0.001 for each). In particular, the emotion subscale of Skindex-29 (p=0.02) and psychosocial negativity subscale of PLQI (p=0.02) were significantly high in psychopathologic patients. A highly positive statistical correlation between Skindex-29 and PLQI scales was evident (r=0.845, p<0.001). For reliability, Cronbach`s coefficient a coefficients were 0.931 for the Skindex-29 scale and 0.918 for the PLQI scale. Conclusion: The results demonstrate that chronic pruritus appreciably reduces the QoL. PLQI could be used in the development of new questionnaires for determining the QoL of patients with chronic itch. (Ann Dermatol 24(4) 406∼412, 2012)

Effects of Chromium Nitrate on Phytohormone Content and Mitotic Activity in Maize (zea Mays L.)Seedlings

Filiz Aygun Erturk,Guleray Agar,Esra Arslan,Medine Gulluce,Metin Turan,Fikrettin Sahin 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Investigation of the Microstructure and Mechanical Characteristics of Lattice Structures Produced by Laser Powder Bed Fusion Method

A. Tamer Erturk,M. Enes Bulduk,Gürkan Tarakçi,Gökhan Özer,Eser Yarar 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.1

This study includes experimental research conducted to produce lattice structures and to examine their mechanical properties by taking advantage of the design freedom provided by additive manufacturing. Much of the existing literature involvesmainly process parameters on mechanical behaviors. Thus, more lattice geometry studies are needed. In this study, diferentlattice structures designed according to the unit cell types selected through the SpaceClaim program were produced usingAlSi10Mg powder material with the laser powder bed fusion (LPBF) method the metal additive manufacturing productionmethods. Cell sizes, Maxwell criterion, relative densities, and mechanical behaviors under semi-static compression forcewere investigated. It was concluded that with increasing relative density, the strength increased, and the structures withstress-dominating were more resistant than those with bending-dominating strength. It was determined that the mechanicalproperties of lattices depended on unit cell design and LPBF process parameters. The C1 and C2 coefcients of latticesproduced by the LPBF process included in the Gibson and Ashby equation were determined.

Low Complexity Video Encoding with One-Bit Transform based Network-Driven Motion Estimation

Hwa-Yong Oh,Erturk, S.,Tae-Gyu Chang IEEE 2007 IEEE transactions on consumer electronics Vol.53 No.2

<P>Low complexity video encoding is desired in many applications requiring real-time encoding of video, particularly for mobile equipment. In order to reduce encoding complexity without much sacrifice in visual quality, some of the complexity can typically be shifted to the decoder, or the network infrastructure can take part in the process by performing some encoding and/or decoding tasks. In this paper a new hybrid video coding scheme is proposed that utilizes the standard motion compensated predictive coding architecture and uses one-bit transform (IBT) representations of video frames to facilitate remote motion estimation. The one-bit transform of each video frame is computed at the encoder using low complexity operations and sent to the decoder or network infrastructure, after entropy encoding, for motion estimation. After motion estimation is carried out remotely, the motion vectors are sent back to the encoder for motion compensated predictive coding. In order to reduce the overhead introduced by one-bit transforms, differential encoding of lBTs is also investigated. The proposed approach can provide low complexity motion compensated predictive video encoding by shifting the high computational load of motion estimation to the decoder or network infrastructure.</P>

Dynamic Finite Element Analysis on Single Impact Plastic Deformation Behavior Induced by SMAT Process in 7075-T6 Aluminum Alloy

Eser Yarar,A. Tamer Erturk,Sedat Karabay 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.8

Surface mechanical attrition treatment (SMAT) is a method that enhances the mechanical properties of metallic materialsby generating a thin nanostructured layer on the top surface. In this study, single-shot impact behavior was modeled for the7075-T6 aluminum alloy to reach maximum values of equivalent stress, plastic strain, deformation depth, residual stressdepth, and residual stress. Finite element simulations have been carried out to analyze the efect of selected parameters onstress and strains in the component. For simulating the SMAT process, a rigid sphere on a rectangular component is modeledusing ANSYS/AUTODYN explicit dynamic solver. The plastic deformation process during SMAT was analyzed accordingto shot velocity and diameter with a dynamic explicit fnite element method (FEM). The response surface methodologywas used to evaluate the parametric results for the SMAT process. In addition, deformation behavior was evaluated after asingle-shot impact according to the restitution coefcient.

Modelling the Thermo-Mechanical Behavior of Magnesium Alloys during Indirect Extrusion

D. Steglich,S. Erturk,J. Bohlen,D. Letzig,W. Brocks 한국소성가공학회 2010 기타자료 Vol.2010 No.6

One of the basic metal forming process for semi-finished products is extrusion. Since extrusion involves complex thermo-mechanical and multiaxial loading conditions resulting in large strains, high strain rates and an increase in temperature due to deformation, a proper yield criterion and hardening law should be used in the numerical modelling of the process. A phenomenological model based on a plastic potential has been proposed that takes strain, strain rate and temperature dependency on flow behaviour into consideration. A hybrid methodology of experiment and finite element simulation has been adopted in order to obtain necessary model parameters. The anisotropy/asymmetry in yielding was quantified by tensile and compression tests of specimens prepared from different directions. The identification of the corresponding model parameters was performed by a genetic algorithm. A fully coupled thermo-mechanical analysis has been used in extrusion simulations for calculation of the temperature field by considering heat fluxes and heat generated due to plastic deformation. The results of the approach adopted in this study appeared to be successful showing promising predictions of the experiments and thus may be extended to be applicable to other magnesium alloys or even other hcp metals.