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( Esref Erturk ),( Meral Mert ),( Yildiz Okuturlar ),( Ozlem Soyluk ),( Pinar Karakaya ),( Ozlem Harmankaya ),( Abaki Kumbasar ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: It is known that vitamin D has effects on the immune system. Vitamin D is an important immune system regulator. Several observational studies show that, vitamin D inhibits proinflammatory processes by suppressing the enhanced activity of immune cells that take part in the autoimmune reaction. It has been suggested that vitamin D may play a role in the pathogenesis of several endocrine diseases, such as autoimmune thyroid diseases, hyperparathyroidism, diabetes mellitus, Addison`s disease. In this study it is aimed to find a correlation between autoimmune thyroid disease and vitamin D. Methods: Thyroid function test result, calcium, PTH and vitamin D levels were compared between a control group of 35 healthy people and 35 patients with a cross-sectional thyroid autoimmune disease. Results: Mean ages are found to be 41.8±14.08 years and 45.6±13.46 years in patients and controls respectively. Mean vitamin D, calcium and parathormone (PTH) levels in patients and control group are found to be 18.6±9.5 vs 39.13 ±14.6 ng/ml, 7.9±0.16 vs 8.67±0.80 mg/dl, 50.7±25.86 vs 56.21±18.17 pg/ml, respectively. Vitamin D levels were found to be significantly lower than the control group in patients with autoimmune thyroid disease. There was no difference between the levels of PTH. Conclusions: Analyzing of vitamin D, PTH and calcium parameters should be considered in patients with autoimmune thyroid diseases. Treatment of vitamin D deficiency may help increase the quality of life in tyroid patients.
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