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      • SCIESCOPUSKCI등재

        Effects of Growth Hormone Gene Polymorphism on Lipogenic Gene Expression Levels in Diaphragm Tissues of Japanese Black Heifers

        Ardiyanti, Astrid,Abe, Tsuyoshi,Tameoka, Nanae,Kobayashi, Eiji,Shoji, Noriaki,Ohtani, Yoshihisa,Suzuki, Keiichi,Roh, Sang-Gun,Katoh, Kazuo Asian Australasian Association of Animal Productio 2012 Animal Bioscience Vol.25 No.8

        Two SNPs, i.e. L127V and T172M, of bovine growth hormone (GH) causing the presence of GH gene haplotypes A, B, and C was previously shown to alter intramuscular fatty acid (FA) composition in Japanese Black (JB) heifers. To determine the SNP effect on somatotropic hormone concentration and lipogenesis, we measured plasma GH, insulin, and insulin-like growth factor-1 (IGF-1) concentrations. We also measured mRNA levels of fatty acid synthase (FASN), stearoyl-coA desaturase (SCD), and sterol regulatory element binding proteins-1 (SREBP-1) and FA composition in diaphragm tissues. Heifers with genotype CC had the lowest plasma insulin concentration and FASN and SCD mRNA levels among genotypes. FASN mRNA levels in haplotype A tended to positively correlate with saturated FA (SFA) content and negatively correlated with C18:2 and unsaturated FA (USFA) contents. SCD mRNA levels in haplotype A positively correlated with monounsaturated FA (MUFA) contents and negatively correlated with C18:0 content. They also tended to positively correlate with C16:1, C18:1, and USFA contents and USFA/SFA ratio and negatively correlate with SFA content. Taken together, GH gene polymorphism affects the lipogenic genes expression levels and their relationships with fatty acid compositions in diaphragm tissues of JB heifers at 31 months of age.

      • AUTO TUNING OF AN AC SERVO MOTOR USING NOVEL REPETITIVE CONTROL METHOD

        Jun Oyama,Tsuyoshi Higuchi,Takashi Abe,Kenichirou Hayashi,Eiji Yamada 전력전자학회 1995 ICPE(ISPE)논문집 Vol.1995 No.10

        For tuning the P1D parameters of an AC servo system, even a skillful engineer takes a long time and these parameteis must be re-tuned according to each application In previous woiks, we proposed a lepetitive control method with learning process to drive the horizontal-axis direct-drive robot arm with constant speed and also applied this control method to the position control in which the arm reciprocates between several points In this paper, we propose an auto tuning method of the AC servo motor Using the repetitive control method especially for periodic speed control It is very simple and powerful Availability of the control methods is confirmed experimentally.

      • The Effect of Asynchronous Carrier on Matrix Converter Characteristics

        Jun OYAMA,Tsuyoshi HIGUCHI,Takashi ABE,Eiji YAMADA,Hideki HAYASHI,Takashi KOGA 전력전자학회 1998 ICPE(ISPE)논문집 Vol.- No.-

        In a matrix converter, input side and output side are coupled with each other through switching elements. Since disturbances on either side affect directly on the other side, it requires a high-speed on-line control system to compensate them.<br/> We proposed in previous papers a new control strategy and an on-line control circuit for a matrix converter. The control circuit could keep the output voltage at commanded value against fluctuation in the supply voltage. Furthermore wave forms of the output voltage and the input current were always kept sinusoidal. The switching pattern was generated by comparing modified voltage references with a carrier. The carrier was synchronized with the supply voltage using a PLL system, which made the control circuitcomplicatedand costly.<br/> This paper discusses on the possibility of an asynchronized carrier. Experiment results show the input current distortion in case of asynchronous carrier is bigger than that of synchronous earner However, the detenoration can be minimized by increased carrier frequency.

      • KCI등재

        Comparison between Bilateral C2 Pedicle Screwing and Unilateral C2 Pedicle Screwing, Combined with Contralateral C2 Laminar Screwing, for Atlantoaxial Posterior Fixation

        Naohisa Miyakoshi,Michio Hongo,Takashi Kobayashi,Tetsuya Suzuki,Eiji Abe,Yoichi Shimada 대한척추외과학회 2014 Asian Spine Journal Vol.8 No.6

        Study Design: A retrospective study. Purpose: To compare clinical and radiological outcomes between bilateral C2 pedicle screwing (C2PS) and unilateral C2PS, combined with contralateral C2 laminar screwing (LS), for posterior atlantoaxial fixation. Overview of Literature: Posterior fixation with C1 lateral mass screwing (C1LMS) and C2PS (C1LMS–C2PS method) is an accepted procedure for rigid atlantoaxial stabilization. However, conventional bilateral C2PS is not always allowed in this method due to anatomical variations of C2 pedicles and/or asymmetry of the vertebral artery. Although unilateral C2PS plus contralateral LS (C2PS+LS) is an alternative in such cases, the efficacy of this procedure has not been evaluated in controlled studies (i.e., with bilateral C2PS as a control). Methods: Clinical and radiological records of patients who underwent the C1LMS–C2PS method, using unilateral C2PS+LS (n=9), and those treated using conventional bilateral C2PS (n=10) were compared, with a minimum two years follow-up. Results: Postoperative complications related to the unilateral C2PS+LS technique included one case of spontaneous spinous process fracture of C2. A C1 anterior arch fracture occurred after a fall in one patient, who underwent bilateral C2PS and C1 laminectomy. No significant differences were seen between the groups in reduction of neck pain after surgery or improvement of neurological status, as evaluated using the Japanese Orthopaedic Association score. A delayed union occurred in one patient each of the groups, with the final fusion rate being 100% in both groups. Conclusions: Clinical and radiological outcomes of unilateral C2PS+LS were comparable with those of the bilateral C2PS fixation technique for the C1LMS-C2PS method.

      • KCI등재

        Limited Clinical Significance of Splenectomy and Splenic Hilar Lymph Node Dissection for Type 4 Gastric Cancer

        Aina Kunitomo,Kazunari Misawa,Yuichi Ito,Seiji Ito,Eiji Higaki,Seiji Natsume,Takashi Kinoshita,Tetsuya Abe,Koji Komori,Yasuhiro Shimizu 대한위암학회 2021 Journal of gastric cancer Vol.21 No.4

        Purpose: Type 4 gastric cancer (GC) has a very poor prognosis even after curative resection, and the survival benefit of splenectomy for splenic hilar lymph node (LN; #10) dissection in type 4 GC remains equivocal. This study aimed to clarify the clinical significance of splenectomy for #10 dissection in patients with type 4 GC. Materials and Methods: The data of a total of 56 patients with type 4 GC who underwent total gastrectomy with splenectomy were retrospectively analyzed. Postoperative morbidity, state of LN metastasis, survival outcomes, and therapeutic value index (TVI) of each LN station were evaluated. TVI was calculated by multiplying the incidence of LN metastasis at each nodal station and the 5-year overall survival (OS) of patients who had metastasis to each node. Results: Overall, the postoperative morbidity rate was 28.6%, and the incidence of #10 metastasis in the patients was 28.6%. The 5-year OS rate for all patients was 29.9%, and most patients developed peritoneal recurrence. Moreover, the 5-year OS rates with and without #10 metastasis were 6.7% and 39.1% (median survival time, 20.4 vs. 46.0 months; P=0.006). The TVI of #10 was as low as 1.92. Conclusions: The clinical significance of splenectomy in the dissection of #10 for type 4 GC is limited and splenectomy for splenic hilar dissection alone should be omitted.

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