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慶北大學校 敎科課程의 改善에 關한 硏究 : The Case of Kyungpook national University
金容圭,李宇一,朴斗元,李慶燮,韓宗烈 慶北大學校 師範大學 1976 敎育硏究誌 Vol.18 No.-
This is the research paper on the curriculum improvement of Kyungpook National University. The curriculum of a college or university is the organized contents of all courses in order to accomplish the educational goals of the higher institution in an effective way. Needless to say, when curriculum is developed, the needs of the society and of the nation where the university is located, should be sufficiently reflected on its development. As an effort toward improving educatioal programs of higher institutions, the Ministry of Education has been encouraging each college or university to engage in the "Pilot Schol Project", a national experimental academic refrom project which was started in 1973 under the sponsorship of the Ministry of Education. In compliance with this policy, Kyungpook National Uuiversity has been not only making its every effort in improving the curriculum by each college within the campus since 1973, but also, continuing its research on the curriculum development in various areas. The research team has been attempted to systematize the direction of the curriculum improvement to meet the needs of the present and of the modern soceity by indicating the particelar characteristics of each college curriculum. This research paper has been focused on testing the validity of the contents of the revised curriculum which covers such areas as the minimum credit hours required for graduation, division making, and sequence of each division, etc.. As a research tool for the purpose of this study, comparative method has been utilized in order to verify the validity of the revised curriculum by means of comparing the above listed items with the current our university curriculum and those of the advanced countries.
Treatment outcomes of extended-field radiation therapy for thoracic superficial esophageal cancer
Lee, Doo Yeul,Moon, Sung Ho,Cho, Kwan Ho,Kim, Tae Hyun,Kim, Moon Soo,Lee, Jong Yeul,Suh, Yang-Gun The Korean Society for Radiation Oncology 2017 Radiation Oncology Journal Vol.35 No.3
Purpose: To evaluate the efficacy and safety of extended-field radiation therapy for patients with thoracic superficial esophageal cancer (SEC). Materials and Methods: From May 2007 to October 2016, a total of 24 patients with thoracic SEC (T1a and T1b) who underwent definitive radiotherapy and were analyzed retrospectively. The median total radiotherapy dose was 64 Gy (range, 54 to 66 Gy) in conventional fractionation. All 24 patients received radiotherapy to whole thoracic esophagus and 23 patients received elective nodal irradiation. The supraclavicular lymph nodes, the celiac lymph nodes, and both of those nodal areas were included in 11, 3, and 9 patients, respectively. Results: The median follow-up duration was 28.7 months (range 7.9 to 108.0 months). The 3-year overall survival, local control, and progression-free survival rates were 95.2%, 89.7%, and 78.7%, respectively. There were 5 patients (20.8%) with progression of disease, 2 local failures (8.3%) and 3 (12.5%) regional failures. Three patients also experienced distant metastasis and had died of disease progression. There were no treatment-related toxicities of grade 3 or higher. Conclusion: Definitive extended-field radiotherapy for thoracic SEC showed durable disease control rates in medically inoperable and endoscopically unfit patients. Even extended-field radiotherapy with elective nodal irradiation was safe without grade 3 or 4 toxicities.
Lee, Doo Yeul,Park, Joong-Won,Kim, Tae Hyun,Lee, Ju Hee,Kim, Bo Hyun,Woo, Sang Myung,Kim, Sang Soo,Lee, Woo Jin,Kim, Dae Yong,Kim, Chang-Min Urban Vogel 2015 STRAHLENTHERAPIE UND ONKOLOGIE Vol.191 No.11
<P>To identify prognostic indicators in patients treated with radiotherapy (RT) for metastases from hepatocellular carcinoma (HCC) in abdominal lymph nodes (LNs).</P>
Lee, Ju-Suk,Kim, Ye-Jin,Ryu, Ki-Hyun,Han, Tae-Ho,Park, Kuen-Woo,Chung, Kyu-Hwan,Lee, Chan,Lee, Gung-Pyo,Kim, Sun-Hyung,Hong, Jin-Sung,Park, Young-Doo,Woo, Eun-Taeck,Park, Sung-Chul,Son, Dae-Yeul 한국원예학회 2012 Horticulture, Environment, and Biotechnology Vol.53 No.2
Pollen of genetically modified (GM) pepper containing the gene for cucumber mosaic virus (CMV) coat protein (CP) and GM Chinese cabbage with high phenylethylisothiocyanate (PEITC) content was investigated for assessment of allergic risk. Amino acid (AA) sequences of the inserted gene products of GM virus resistant pepper and GM Chinese cabbage with high PEITC content were compared with those of known allergens. No known allergen greater than 35% AA sequence homology, over 80 AA window or more than 8 consecutive identical AA was found. Protein patterns of GM/non-GM pepper and Chinese cabbage pollen extracts in SDS-PAGE analysis showed the same distribution of protein bands among the GM and non-GM pepper or Chinese cabbage, respectively. Sera from pollen allergic patients showed some IgE reactivity via immunoblotting and ELISA; however, no differences were observed between the pollen of GM and non-GM pepper or Chinese cabbage, respectively. Based on these results, we conclude that pollens of the virus resistant GM pepper and GM Chinese cabbage with high PEITC have no differences in their protein composition or allergenicity relative to non-GM pepper and Chinese cabbage.
근사화된 통계식과 주파수 강조방식을 이용한 윤곽선 추출방법
이두열(Doo Yeul Lee),윤형태(Hyung Tae Yoon),김훈학(Hoon Hak Kim),김병찬(Byung Chan Kim) 한국정보과학회 1989 정보과학회논문지 Vol.16 No.1
윤곽선 추출은 임의의 영상정보로 부터 화질의 변화율이 급격한 부분을 규명하는 작업이라 할 수 있다. 본 논문에서는 특정화상이 아닌 자연화상 정보로 부터 윤곽선을 추출할 수 있는 새로운 방법을 보였다. 본 논문에서 제안한 처리과정은 필터링과 주파수 강조, 화소분포의 평활화, 그리고 근사화시킨 통계식을 이용한 윤곽선 추출의 3과정을 수행하게 되며 각 처리과정에 대한 수학적인 개념을 근사화시킨 식을 이용함으로써 실제 처리과정상의 시간지연의 요소를 극소화시켰다. 끝으로 기존의 여러가지 연산자를 이용한 방식과 통계처리 방식을 4절에서 비교하였다. Edge detection is the process for characterizing the intensity changes in an image. This paper describes a new method for extracting edges from natural image. The proposed method of edge detection consists of three steps, a filtering and frequency emphasis step, an equalizing step and an approximated statistical classification step. Following three step, this paper describes in de1ail the following theoritical aspects. 1) highpass filtering and frequency emphasis for an image sharpening. 2) histogram equalization for an image enhancement. 3) approximated statistical classification for an edge detection from a noiseless and noisy image. Finally, the proposed method is compared to the classical method using a operators and to Suk's statistical method.
Methicillin-Resistant Staphylococcus aureus에 대하여 EDTA 및 Sodium Azide 병용에 의한 (+)-Usnic Acid 약효증가
Young Seob Lee,Jae Won Lee,Doo Jin Choi,Dae Young Lee,Kyung Hye Seo,Hyung Don Kim,Seung Eun Lee,Dong Yeul Kwon,Bu Min Kim,Geum Soog Kim 한국약용작물학회 2017 한국약용작물학술대회 발표집 Vol.2017 No.05
Background : Methicillin-Resistant Staphylococcus aureus (MRSA) is a multidrug-resistant (MDR) strain. Especially, MRSA is developing resistance to available antibacterial agents and causing complications in the treatment of infections related to skin, soft tissue, respiratory, bone, joint, and endovascular disorders. Therefore, antibacterial agent combination therapy appears to be a useful option, particularly in developing countries where antibiotic availability is limited. (+)-Usnic acid (UA) is uniquely found in lichens, and is especially abundant in genera such as Usnea and Cladonia. UA has antimicrobial activity against human and plant pathogens. Therefore, UA may be a good antibacterial drug candidate for clinical development. Methods and Results : In search of a natural products capable of inhibiting this multidrug-resistant bacteria, we have investigated the antimicrobial activity of UA against MRSA. In this study, the effects of a combination of UA and permeable agents against MRSA were investigated. For the measurement of cell wall permeability, UA with concentration of Ethylenediaminetetraacetic acid (EDTA) was used. In the other hand, Sodium azide (NaN3) was used as inhibitors of ATPase. These results suggest that the antibacterial effect of UA was potentiated by membrane-binding agents and ABC transporter-inhibiting agents, implying that antibacterial activity is associated with damage of the cell wall and inhibition of ATPase function by UA. Conclusion : UA and in combination with EDTA and NaN3 could lead to the development of new combination antibiotics against MRSA infection. The results of this study appear to be promising, and they are expected to enhance the use of natural products as drugs.