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박두순,이순흠 순천향대학교 부설 산업기술연구소 1997 순천향 산업기술연구소논문집 Vol.3 No.2
The development of computer network has made us provide a variety of information speedily and correctly. Many people want to use information to which we are desire to access. To provide such a information service we design and implement the Korea Pottery Information Retrieval System. Our proposed system provides a real time processing service. We might conclude as follows. (1) Development of data model for multimedia information management (2) Design and implementation technique of thesaurus schema for pottery information (3) Design technique of information service system based on multimedia data (4) Design and implementation technique of API between DBMS and user interface
Correlation between the Severity of Obstructive Sleep Apnea and Heart Rate Variability Indices
Park, Doo-Heum,Shin, Chul-Jin,Hong, Seok-Chan,Yu, Jaehak,Ryu, Seung-Ho,Kim, Eui-Joong,Shin, Hong-Beom,Shin, Byoung-Hak The Korean Academy of Medical Sciences 2008 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.23 No.2
<P>The risk of cardiovascular disease is known to be increased in obstructive sleep apnea syndrome (OSAS). Its mechanism can be explained by the observation that the sympathetic tone increases due to repetitive apneas accompanied by hypoxias and arousals during sleep. Heart rate variability (HRV) representing cardiac autonomic function is mediated by respiratory sinus arrhythmia, baroreflex-related fluctuation, and thermoregulation-related fluctuation. We evaluated the heart rate variability of OSAS patients during night to assess their relationship with the severity of the symptoms. We studied overnight polysomnographies of 59 male untreated OSAS patients with moderate to severe symptoms (mean age 45.4± 11.7 yr, apnea-hypopnea index [AHI]=43.2±23.4 events per hour, and AHI >15). Moderate (mean age 47.1±9.4 yr, AHI=15-30, n=22) and severe (mean age 44.5±12.9 yr, AHI >30, n=37) OSAS patients were compared for the indices derived from time and frequency domain analysis of HRV, AHI, oxygen desaturation event index (ODI), arousal index (ArI), and sleep parameters. As a result, the severe OSAS group showed higher mean powers of total frequency (TF) (<I>p</I>=0.012), very low frequency (VLF) (<I>p</I>= 0.038), and low frequency (LF) (<I>p</I>=0.002) than the moderate OSAS group. The LF/HF ratio (<I>p</I>=0.005) was higher in the severe group compared to that of the moderate group. On the time domain analysis, the HRV triangular index (<I>p</I>=0.026) of severe OSAS group was significantly higher. AHI was correlated best with the LF/HF ratio (r<SUB>p</SUB>=0.610, <I>p</I><0.001) of all the HRV indices. According to the results, the frequency domain indices tended to reveal the difference between the groups better than time domain indices. Especially the LF/HF ratio was thought to be the most useful parameter to estimate the degree of AHI in OSAS patients.</P>
Sumin Hong(Sumin Hong),Doo-Heum Park(Doo-Heum Park),Seung-Ho Ryu(Seung-Ho Ryu),Jee Hyun Ha(Jee Hyun Ha),Hong Jun Jeon(Hong Jun Jeon) 대한정신약물학회 2022 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.20 No.4
Objective: Heart rate variability (HRV) reflects the regulation of the autonomic nervous system. Panic disorder is highly associated with autonomic dysfunction, and is often accompanied by depression. The aim of this study is to determine the association between depression and HRV indices in patients with panic disorder. Methods: A total of 110 outpatients diagnosed with panic disorder participated in this study. The medical records of patients with panic disorder who visited the outpatient clinic of Konkuk University Hospital between December 2018 and March 2020 were retrospectively reviewed. Measurements used in this study include the Panic Disorder Severity Scale-Self Report, Beck Depression Inventory (BDI-II), Insomnia Severity Index, and HRV. Patients were divided into depressive and non-depressive groups based on their BDI-II scores. The association between HRV indices and depressive symptoms was statistically analyzed. Results: The low frequency/high frequency (LF/HF) ratio was reduced in patients with depression (mean = −0.095, p = 0.004 in the above moderate depressive group, mean = −0.120, p = 0.020 in the severe depressive group). Significant correlations were found between depressive symptoms and standard deviation of NN interval (SDNN) (ms) (−0.19, p = 0.044), very low frequency (VLF) (ms2/Hz) (−0.22, p = 0.021), LF (−0.25, p = 0.008), HF (−0.19, p = 0.043), and LF/HF (−0.25, p = 0.009). Multiple linear regression analysis showed that BDI predicted SDNN (ms), VLF (ms2/Hz), LF, HF, and LF/HF. Conclusion: We confirmed that the LF/HF ratio decreases when depression is accompanied by panic disorder. HRV indices may be useful markers for detecting depressive symptoms in patients with panic disorder.
Preparation and Photopolymerization of 22-Tricosenol Langmuir-Blodgett Films
Park, Yun Heum,Ahn, Tae Bin,Baik, Doo Hyun,Kim, Keon Hyeong,Jo, Won Ho 한국공업화학회 2003 Journal of Industrial and Engineering Chemistry Vol.9 No.4
Amphiphilic monomer, 22-tricosenol was synthesized from the reduction of 22-tricosenoic acid. The stability of 22-tricosenol monolayer was investigated and compared with that of the 22-tricosenoic acid monolayer. The 22-tricosenol monolayer was deposited on solid substrates, such as KRS-5 (TiBr/TiI) and silicon wafer, by employing Langmuir-Blodgett (LB) technique under the deposition condition of 23"C, pH 5.4, and the surface pressure of 33 mN/m. The polymerization of the 22-tricosenol monomer LB films was carried out by UV-irradiation for 240 seconds. The polymerized LB film was insoluble in ethanol and acetone which were good solvents for the monomer LB film. The negative resist pattern was generated by exposing the masked monomer LB film to UV-irradiation followed by dissolving the unirradiated part with ethanol.
박두흠,Park, Doo-Heum 대한수면의학회 1999 수면·정신생리 Vol.6 No.1
A growing number of people are concerned about their sleep. There are many people with chronic sleep disorders. Sedativehypnotics including benzodiazepine and non-benzodiazepine have been widely used in chronic insomniacs. It is widely accepted that current hypnotics are efficient in alleviating subjective symptoms of insomnia. Non-benzodiazepine hypnotics include zolpidem, zopiclone, and melatonin. These novel non-benzodiazepine hypnotics that have efficacy comparable to benzodiazepines were developed with more understanding of benzodiazepine receptor pharmacology. Their unique pharmacologic profiles may offer few significant advantages in terms of adverse effects of benzodiazepines. However, most of hypnotics including non-benzodiazepine have some of dependence, tolerance, impaired daytime function and rebound insomnia. Currently, it is accepted that combination therapy with pharmacologic and behavioral intervention is the most effective for chronic insomniacs.