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음용수 중의 무기원소 분석 1. 몇 가지 무기원소들의 ICP-AES 검정곡선
남상호,한동설,김민재,이상좌 木浦大學校基礎科學硏究所 1999 基礎科學硏究誌 Vol.17 No.-
The ICP-AES calibration curves for 9 inorganic elements (Pb, As, Hg, Cd, Cu, Zn, Fe, Mn, and Al) which can affect seriously to human health were presented. These were tested by NIST samples, and the difference in concentration were within 1%. The ICP-AES calibration curves were applied to trace analysis of the 5 samples taken in Mokpo National University. Hg and Cd were not found in all samples in this work, but the amount of Zn was measured a bit more than standard level (1.0 ppm) in samples 1 and 2. It was appeared that Mn was contained in sample 1 only more than standard level(0.3 ppm).
수용성 미셀용액 내에서의 몇가지 안트라센 유도체의 광증감 작용에 미치는 pH 영향
高晟三,한동설,金純鍾 木浦大學校基礎科學硏究所 1996 基礎科學硏究誌 Vol.14 No.-
To examine the photosensitizing properties of 9-methylanthracene and 9-phenyl-anthracene, the concentration change of DPBF was determined during the irradiation with the light of 366nm in 95% MeOH, SDS and CTAB aqueous micellar solution at various pH. The concentration decreasing of DPBF by photosensitization was fast at low pH and especially was found to be very sensitive to the changes of pH in the range 4∼6. At high pH, the produced singlet oxygen seemed to be decayed by the reaction of OH. And it was found that the concentration of DPBF was decreased more fast in 95% MeOH solution than in aqueous micellar solution. Such results are believed that environment of the aqueous micellar solutions is more polar than that of 95% MeOH. It was also found that the 9-PA was more effective photosensitized than 9-MA, and the abilities of 9-PA and 9-MA to photosensitize oxidation reaction were found to be greater in SDS aqueous micellar solution than in CTAB aqueous media.
4-비닐피리딘계 이온 교환수지의 합성 및 그의 이온 교환능에 대한 연구
박병관,한동설 木浦大學校基礎科學硏究所 1984 基礎科學硏究誌 Vol.2 No.-
The ion exchangers such as 4-vinylpyridine-vinylacetate-divinylbenzene, 4-vinylpyridine-vinylalcohol-divinylbenzene and 4-vinylpyridine-vinylphosphate-divinylbenzene were prepared and the compositions of the above ion exchangers were confirmed by their infrared absorption spectra. The ion exchange capacities of the ion exchangers were examined and the adsorption properties of metal ion for them were also investigated. The ion exchange capacities of 4-VPVADVB, 4-VPVALDVB and 4-VPVPDVB were 1.8meq/g, 2.5meq/g and 4.1meq/g respectively.
E. coli 과량발현을 통한 B형 간염 바이러스 preS1 유도체의 안정한 동위원소 N의 치환
박병관,김세하,한규훈,김선영,홍요정,이시형,한동설,김순종,박진구 木浦大學校基礎科學硏究所 1997 基礎科學硏究誌 Vol.15 No.-
We have used molecular biology technique to label the side chains and backbone of HBV preS1(1-56) with stable isotope (??) during E. coli over-expression and purified the protein to near homogeneity. The expression level of ?? labelled preS1(1-56) seems to be ∼15% of the total protein. to characterize the secondary structure of the labelled protein, circular dichroism was used. In different buffer conditions including pH 3.3 and pH 7.4 the protein seems to be devoid of any stable secondary structure probably suggesting that the N-terminal portion (preS1(1-56)) of HBV preS1 might be unstructured before binding to its target cells.
가토에서 일측 요관 부분 및 완전폐색시 신장과 요관의 조직학적 변화
김상현,김용웅,육승모,한동석,노안식,임재성,김홍식,나용길,설종구 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2
This study was designed to clarify histologic changes in the experimental rabbit kidney and ureter after unilateral partial or complete ureteral obstruction. A total of 20 adult white rabbits were divided into 4 subgroups in the partial obstruction followed by 2 weeks, the partial obstruction followed by 4 weeks, the complete obstruction followed by 2 weeks, and the complete obstruction followed by 4 weeks. The normal control group was consisted of 5 adult white rabbits. The kidneys and ureters for light microscopy were fixed in 10% neutral formalin, embedded in paraffin and stained with hematoxylin and eosin. Abnormal histologic fingings showed in ipsilateral kidney and ureter of all subgroups(such as dilatation of uriniferous tubule, focal necrosis and desquamation of epithelium, interstitial fibrosis, glomerular congestion, widening of Bowman's space, dilatation of ureter, epithelial cell atrophy or loss, interstitial fibrosis and interstitial inflammation). These findings were most severe in the group of the complete-obstructed ureter for 4 weeks. No significant changes showed in contralateral ureter of all subgroups. The degree of obstruction was severe and period of obstruction was long, the histological changes in ipsilateral side were severe. Despite of changes in ipsilateral side no abnormal findings showed in contralateral side. We suggest that long term experimental investigation of histologic changes in ipsilateral side and compensatory changes in contralateral side have to be studied.
표재성 방광암에서 Bacillus Calmette-Guerin 방광 내 주입요법 : 장기적 추적결과 Long-term Follow up Results
김용웅,왕세환,육승모,한동석,노안식,나용길,설종구 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2
To evaluated the results of long-term follow up of superficial bladder cancer patients who were treated with transurethral resection and intravesical BCG therapy. Between April 1989 and December 1997, 65 patients with superficial bladder cancer were treated with TUR-B(Transurethral resection of bladder tumor) and intravesical BCG instillation, and follow-up was performed for 5 years longer, and the mean follow-up duration was 82 months. Of 65 patients, pathologic stage were Ta in 17 cases and T1 in 48 cases and grade were G Ⅰ in 22 cases, G Ⅱ in 35 cases and G Ⅲ in 8 cases. The tumor recurred in 22(33.8%) at the median of 21.8 months and the tumor progressed in 9(13.8%) at the median of 20.8 months. Most of the recurrences and progression were within 3 year(838 and 77%). Progression is more likely in higher grade(G Ⅱ, G Ⅲ) and higher stage(T1). The complete response rate after first and second courses of BCG therapy were 53% and 73% and the 5 and 10 year disease specific survival rates were 89.5 and 78% respectively. The complete response rate after first and second courses of BCG therapywere 53% and 73%. Most of recurrences and progressions were within 3 years of the BCG therapy, but some cases occured after 5 years. Therefore, close long-term follow up is needed.
Photosensitizing Property of Emodin Glucoside
Han,Dong-Sul,Kim,Chong-Hyun 木浦大學校基礎科學硏究所 1985 基礎科學硏究誌 Vol.3 No.-
The photosensitizing property of emodin glucoside was examined. The chemical evidence for involvement of singlet oxygen during the photo-irradiation for the emodin glucoside was based, with appropriate experiments, on the rapid disappearance of DPBF. The β value for DPBF in methanol was determined by using emodin glucoside as the singlet oxygen sensitizer. Resulting β value was ??.
Photosensitizing Property of Some Anthraquinone Derivatives
Han, Dong-Sul,Park, Byung-Kwan 木浦大學校基礎科學硏究所 1988 基礎科學硏究誌 Vol.6 No.-
The photosensitizing property of some anthraquinone derivatives was examined. The chemical evidence for involvement of singlet oxygen during photoirradiation for chrysophanol glucoside, physcion glucoside and quinalizarin was based on the rapid disappearance of DPBF in appropriate experiments. And the βvalue for DPBF in methanol solution was determined by using chryso-phanol glucoside as the singlet oxygen sensitizer. Resulting βvalue was ??.
A high performance CPW 4 × sub-harmonic mixer using anti-parallel diode pair (APDP)for the V-band
Woo-Suk Sul,Han-Sin Lee,Sung-Chan Kim,Hyo-Jong Han,Won-Young Uhm,Dan An,Sam-Dong Kim,Dong-Hoon Shin,Hyung-Moo Park,Jin-Koo Rhee 한국물리학회 2004 Current Applied Physics Vol.4 No.1
In this paper,we present a high performance V-band quadruple sub-harmonic mixer monolithic circuit which is designed andfabricated for the millimeter wave down converter applications. While the typical sub-harmonic mixer use a half of fundamentalfrequency,we adopt a quarter of the fundamental frequency. The proposed circuit is based on typical sub-harmonic mixer with anti-parallel diode pair (APDP). Upon the typical mixer design,additional stubs are placed with the modication of original stub length.The stubs,0.1l m pseudomorphic high electron mobility transistors (PHEMTs) and other components are appropriately positionedto each port for maximizing quarter frequencies. Maximum conversion gain of 0.8 dB at a LO frequency of 14.5 GHz and at a RFfrequency of 60.4 GHz is measured. Both LO-to-RF and LO-to-IF isolations are higher than 40 dB. The achieved result of con-version gain and isolation characteristic is one of the best performances reported among the quadruple sub-harmonic mixeroperating in the V-band millimeter wave frequency.