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Thi Binh Nguyen Nguyen,Thi Kieu Diem Nguyen,Van Hue Trương,Thi Tuyet Ngoc Tran,van Bao Thang Phan,Thi Tuyen Nguyen,Hoang Bach Nguyen,Viet Quynh Tram Ngo,Van Tuan Mai,Paola Molicotti 질병관리본부 2023 Osong Public Health and Research Persptectives Vol.14 No.5
Objectives: Tuberculosis (TB) and drug-resistant TB (DR-TB) are national health burdens in Vietnam. In this study, we investigated the prevalence of rifampicin (RIF) and/or isoniazid (isonicotinic acid hydrazide, INH) resistance in patients with suspected TB, and applied appropriate techniques to help rapidly target DR-TB. Methods: In total, 1,547 clinical specimens were collected and cultured using the BACTEC MGIT system (Becton Dickinson and Co.). A resazurin microtiter assay (REMA) was used to determine the proportions of RIF and/or INH resistance. A real-time polymerase chain reaction panel with TaqMan probes was employed to identify the mutations of rpoB and katG associated with DR-TB in clinical isolates. Genotyping of the identified mutations was also performed. Results: A total of 468 Mycobacterium tuberculosis isolates were identified using the REMA. Of these isolates, 106 (22.6%) were found to be resistant to 1 or both antibiotics. Of the resistant isolates, 74 isolates (69.8%) were resistant to isoniazid (INH) only, while 1 isolate (0.94%) was resistant to RIF only. Notably, 31 isolates (29.24%) were resistant to both antibiotics. Of the 41 phenotypically INH-resistant isolates, 19 (46.3%) had the Ser315Thr mutation. There were 8 different rpoB mutations in 22 (68.8%) of the RIF-resistant isolates. The most frequently detected mutations were at codons 531 (37.5%), 526 (18.8%), and 516 (6.3%). Conclusion: To help prevent new cases of DR-TB in Vietnam, it is crucial to gain a comprehensive understanding of the genotypic DR-TB isolates.
Dinh, Thi Hinh,Tran, Vu Diem Ngoc,Nguyen, Thi Thao,Hoang, Quyen Thi Ngoc,Han, Hyoung–,Su,Lee, Jae–,Shin Elsevier 2017 CERAMICS INTERNATIONAL Vol.43 No.18
<P><B>Abstract</B></P> <P>This study investigated the microstructure, dielectric, ferroelectric, and strain properties of lead‒free 0.995Bi<SUB>1/2</SUB>(Na<SUB>0.82</SUB>K<SUB>0.18</SUB>)<SUB>1/2</SUB>TiO<SUB>3</SUB>–0.005BaZrO<SUB>3</SUB>/0.98Bi<SUB>1/2</SUB>(Na<SUB>0.78</SUB>K<SUB>0.22</SUB>)<SUB>1/2</SUB>TiO<SUB>3</SUB>–0.02LaFeO<SUB>3</SUB> (BNKT18BZ/BNKT22LF) ceramic composites. We found that the required electric field for trigging the phase transition from ergodic relaxor (ER) to ferroelectric of BNKT18BZ/BNKT22LF ceramic composites can be effectively decreased by adding BNKT18BZ as nonergodic relaxor (NER) with changes of three different stabilized regions and the highest <I>S</I> <SUB>usable</SUB> peak points as a function of the applied electric field. The highest <I>d</I> <SUB>33</SUB> <SUP>*</SUP> value of 690p.m./V was obtained at 4kV/mm for 0.3wt BNKT18BZ fraction ceramic composites. This value was higher than 575 p.m./V of BNKT22LF ceramics under an applied electric field of 5kV/mm.</P>
Giant Strain in Lead-free Relaxor/Ferroelectric Piezocomposite Ceramics
Thi Hinh Dinh,Jin-Kyu Kang,Hoang Thien Khoi Nguyen,Trang An Duong,Jae-Shin Lee,Vu Diem Ngoc Tran,Ky Nam Pham 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.68 No.12
The crystal structural, ferroelectric, and electric-field-induced-strain (EFIS) properties of leadfree relaxor/ferroelectric piezocomposites were investigated. The relaxor-matrix phases were mixed with the ferroelectric-seed phases by using a conventional ceramic processing route. The addition of the ferroelectric seed phase dramatically enhanced the EFIS of the relaxor matrix phase at low electric fields. Giant strains of 745 pm/V at 4 kV/mm and 466 pm/V at 3 kV/mm were obtained when the seed contents were 30 wt% and 50 wt%, respectively, which are much higher than those of the relaxor matrix phase without ferroelectric seeds (575 pm/V at 4 kV/mm and 327 pm/V at 3 kV/mm).