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David Wu,George Mansoor,Christian Kempf 대한고혈압학회 2015 Clinical Hypertension Vol.21 No.15
Introduction: Hypertension, a risk factor for cardiovascular disease (CVD), is frequently associated with other CVD risk factors. Despite recent improvement in blood pressure (BP) control in Europe, a substantial proportion of patients fail to achieve BP targets. Methods: This retrospective cohort study used longitudinal patient databases (LPDs) in France and Italy to examine CVD risk profiles, treatment patterns, and BP goal attainment in hypertensive patients treated in real-world clinical practice between 2007 and 2008. Overall, 147,964 and 140,189 eligible patients from LPDs in France and Italy, respectively, were prescribed an antihypertensive medication in 2007. Results: Among patients with hypertension with other risk factors (France 88 %, Italy 83 %), the most prevalent risk factors were being elderly (France 66.9 %, Italy 70. 9 %), followed by hypertension combined with dyslipidemia (France 36.7 %, Italy 23.9 %) and isolated systolic hypertension (France 32.5 %, Italy 24.2 %). The odds ratios for target BP attainment were significantly (p < 0.001) higher in patients with hypertension without other risk factors vs patients with hypertension with other risk factors (1.41 [95 % confidence interval 1.35, 1.48] in France; 1.38 [1.31, 1.46] in Italy). The odds of BP control were significantly lower for patients with vs patients without an associated CVD risk factor (range 0.54 to 1.10 France; 0.59 to 1.17 Italy). Discussion: This study demonstrates that the majority of treated hypertensive patients in France and Italy have at least one additional CVD risk factor. Despite treatment with antihypertensive medications, blood pressure attainment was substantially less optimal in patients with an associated CVD risk factor compared to patients without an associated CVD risk factor.
Wu, Yiyan,Zhao, Zhenglin,Yang, Yupeng,Yang, Xudong,Jang, Eun Young,Schilaty, Nathan D,Hedges, David M,Kim, Sang Chan,Cho, Il Je,Zhao, Rongjie Chinese Medical Assn 2014 Chinese medical journal : CMJ Vol.127 No.10
<P>We previously demonstrated that the aqueous extract of the Schizandra chinensis fruit (AESC) ameliorated Cd-induced depletion of monoamine neurotransmitters in the brain through antioxidant activity. In the present study, we investigated the effect of AESC on anxiety-like behavior and the levels of norepinephrine and 3-methoxy-4-hydroxy-phenylglycol (a metabolite of norepinephrine) in different brain regions during ethanol withdrawal in rats.</P>
Investigation of muscle-specific beef color stability at different ultimate pHs
Wu Shuang,Han Jina,Liang Rongrong,Dong Pengcheng,Zhu Lixian,Hopkins David L.,Zhang Yimin,Luo Xin 아세아·태평양축산학회 2020 Animal Bioscience Vol.33 No.12
Objective: This study was aimed to investigate the muscle-specific beef color stability at normal and high ultimate pHs. Methods: The impact of muscle (Longissimus lumborum [LL] vs psoas major [PM]) and pH (normal ultimate pH [Np] vs high pH dark cutting beef [Hp]) on color stability, indicated by basic color traits, metmyoglobin reducing activity (MRA) and oxygen consumption (OC), as well as the lipid oxidation, were determined over 7 days of display at 4°C. Results: Hp-LL had the highest pH (6.92), followed by Hp-PM (6.01), Np-PM (5.76), and Np-LL (5.52). Hp-LL had increased (p<0.05) a*, chroma and % oxymyoglobin during display. Hp-LL also had the highest metmyoglobin (MMb) reducing activity and OC among all the samples, thus, the greatest color stability, although very dark throughout storage, with lowest values for lightness (L*) and yellowness (b*). Np-LL also exhibited relatively high color stability, as a result of its lower % MMb and OC and higher MRA than psoas muscle samples. The 0.2 unit difference of the pH between Hp and Np psoas muscle, resulted in the difference of the color intensity, not the color stability. Interestingly, high pH psoas muscle (Hp-PM) did not have better color stability than Np-PM, and in fact had lower color stability than even Np-LL. The similar level of OC and lipid oxidation cannot explain the difference in color stability between Hp-PM and Np-LL. Conclusion: The Hp does not always show better color stability compared with Np beef, which depends on the muscle type. The balance of MRA and OC is important to keep the color in great intensity and stability in the meantime.
Enterprise Risk Management and Information Systems Security Risk
David L. Olson,Desheng WU 인하대학교 정석물류통상연구원 2009 인하대학교 정석물류통상연구원 학술대회 Vol.2009 No.10
Risks of all forms are of interest in enterprise risk management. This paper reviews risks associated with information system(IS), to include support of supply chains. Categories of IS risk are reviewd, along with frameworks that have been presented for the control of IS risk. A generic IS security process is given, along with best practices.
이승재,David F. Parrish,박세영,Wan-Shu Wu,Steven J. Greybush,이우진,Steven J. Lord 한국기상학회 2011 Asia-Pacific Journal of Atmospheric Sciences Vol.47 No.4
In this study, we assimilate 2-m air temperature data with the National Centers for Environmental Prediction (NCEP) regional Gridpoint Statistical Interpolation (GSI) using the WRF-NMM model forecast as a first guess. Single time analysis experiments are conducted to test the impact of 2-m air temperature data on the analysis system and the results are compared with the control run without using 2-m air temperature data. The effort is focused on understanding the characteristics of observation innovations of the 2-m air temperature data. Modifications to background errors and a simple test of nonlinear quality control are also considered. The incorporation of a comprehensive near-surface observation operator based on Monin-Obukhov similarity theory is described and tested for possible operational use with the NCEP regional GSI system. The results from this new forward operator are compared with those from the existing simple forward operator. According to the results, mesonet 2-m temperature data were found to have a considerable amount of outliers compared with other 2-m temperature data. The nighttime western and central US domains indicated a model warm bias. Stations with large innovations are distributed uniformly in the nighttime western and central domains,while they are mainly located in the large cities in the daytime eastern domain. The statistical analysis of observation innovations showed that introduction of the new forward model can reduce root-mean-square errors in observation increment statistics. The results of a short assimilation experiment indicate that the new forward operator can be employed as a short-term strategy for near-surface data assimilation in the NCEP