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      • KCI등재

        2D representation of life cycle greenhouse gas emission and life cycle cost of energy conversion for various energy resources

        안태규,김희태,Claudio Tenreiro 한국화학공학회 2013 Korean Journal of Chemical Engineering Vol.30 No.10

        We suggest a 2D-plot representation combined with life cycle greenhouse gas (GHG) emissions and life cycle cost for various energy conversion technologies. In general, life cycle assessment (LCA) not only analyzes at the use phase of a specific technology, but also covers widely related processes of before and after its use. We use life cycle GHG emissions and life cycle cost (LCC) to compare the energy conversion process for eight resources such as coal, natural gas, nuclear power, hydro power, geothermal power, wind power, solar thermal power, and solar photovoltaic (PV) power based on the reported LCA and LCC data. Among the eight sources, solar PV and nuclear power exhibit the highest and the lowest LCCs, respectively. On the other hand, coal and wind power locate the highest and the lowest life cycle GHG emissions. In addition, we used the 2D plot to show the life cycle performance of GHG emissions and LCCs simultaneously and realized a correlation that life cycle GHG emission is largely inversely proportional to the corresponding LCCs. It means that an expensive energy source with high LCC tends to have low life cycle GHG emissions, or is environmental friendly. For future study, we will measure the technological maturity of the energy sources to determine the direction of the specific technology development based on the 2D plot of LCCs versus life cycle GHG emissions.

      • SCISCIESCOPUS

        Monte Carlo calculated TG-60 dosimetry parameters for the β− emitter S153m brachytherapy source : Dosimetry parameters for S153m brachytherapy source

        Sadeghi, Mahdi,Taghdiri, Fatemeh,Hamed Hosseini, S.,Tenreiro, Claudio Wiley (John WileySons) 2010 Medical physics Vol.37 No.10

        <P>PURPOSE: The formalism recommended by Task Group 60 (TG-60) of the American Association of Physicists in Medicine (AAPM) is applicable for beta sources. Radioactive biocompatible and biodegradable 153Sm glass seed without encapsulation is a beta- emitter radionuclide with a short half-life and delivers a high dose rate to the tumor in the millimeter range. This study presents the results of Monte Carlo calculations of the dosimetric parameters for the 153Sm brachytherapy source. METHODS: Version 5 of the (MCNP) Monte Carlo radiation transport code was used to calculate two-dimensional dose distributions around the source. The dosimetric parameters of AAPM TG-60 recommendations including the reference dose rate, the radial dose function, the anisotropy function, and the one-dimensional anisotropy function were obtained. RESULTS: The dose rate value at the reference point was estimated to be 9.21 +/- 0.6 cGy h(-1) microCi(-1). Due to the low energy beta emitted from 153Sm sources, the dose fall-off profile is sharper than the other beta emitter sources. The calculated dosimetric parameters in this study are compared to several beta and photon emitting seeds. CONCLUSIONS: The results show the advantage of the 153Sm source in comparison with the other sources because of the rapid dose fall-off of beta ray and high dose rate at the short distances of the seed. The results would be helpful in the development of the radioactive implants using 153Sm seeds for the brachytherapy treatment.</P>

      • SCISCIESCOPUS

        Monte Carlo calculation of dosimetry parameters for the IR08-P103d brachytherapy source : Dosimetry parameters for the IR08-P103d brachytherapy

        Saidi, Pooneh,Sadeghi, Mahdi,Shirazi, Alireza,Tenreiro, Claudio Wiley (John WileySons) 2010 Medical physics Vol.37 No.6

        <P>PURPOSE: For the treatment of some cancerous tumors using brachytherapy methods and low-energy photon sources, such as 125I and 103Pd, the American Association of Physicists in Medicine Task Group No. 43U1 report recommends that the dosimetric parameters of a new brachytherapy source must be determined in two experimental and Monte Carlo theoretical methods before using each new source clinically. This study presents the results of Monte Carlo calculations of the dosimetric parameters for IR08-103Pd brachytherapy source design. IR08-103Pd seed has been manufactured at the Agricultural, Medical and Industrial Research School. METHODS: Version 5 of the (MCNP) Monte Carlo radiation transport code was used to calculate the dosimetry parameters around the source. Three geometric models of the seed, based on different locations of beads inside the titanium capsule, were simulated. The seed contains five resin beads of 0.6 mm diameter having 103Pd uniformly absorbed in the bead volume, which were contained within a cylindrical titanium capsule having 0.8 mm outside diameter and 4.8 mm length. RESULTS: The Monte Carlo calculated dose rate constant of the IR08-103Pd seed was found to be 0.695 +/- 0.021 cGyU(-1) h(-1). Also in this study, the geometry function G(r, theta), line and point-source radial dose functions gL(r) and gP(r), and the anisotropy function F(r, theta), have been calculated at distances from 0.25 to 7 cm. The results of these calculations have been compared with measured values for an actual IR08-103Pd seed. CONCLUSIONS: There are no statistical significant dosimetric differences among the three seed orientations in this study (i.e., ideal, vertical, and diagonal). However, the observed differences between the calculated and measured values could be explained by the measurement uncertainty and the configuration of the resin beads within the capsule and capsule orientation.</P>

      • Preparation of radioactive praseodymium oxide as a multifunctional agent in nuclear medicine: expanding the horizons of cancer therapy using nanosized neodymium oxide

        Bakht, Mohamadreza K.,Sadeghi, Mahdi,Ahmadi, Seyed J.,Sadjadi, Sodeh S.,Tenreiro, Claudio Lippincott Williams Wilkins, Inc. 2013 Nuclear medicine communications Vol.34 No.1

        OBJECTIVE: Many studies have attempted to assess the significance of the use of the &bgr;-particle emitter praseodymium-142 (Pr) in cancer treatment. As praseodymium oxide (Pr2O3) powder is not water soluble, it was dissolved in HCl solution and the resultant solution had to be pH adjusted to be in an injectable radiopharmaceutical form. Moreover, it was shown that the nanosized neodymium oxide (Nd2O3) induced massive vacuolization and cell death in non-small-cell lung cancer. In this work, the production of Pr was studied and water-dispersible nanosized Pr2O3 was proposed to improve the application of Pr in nuclear medicine. MATERIALS AND METHODS: Data from different databases pertaining to the production of Pr were compared to evaluate the accuracy of the theoretical calculations. Water-dispersible nanosized Pr2O3 was prepared using a poly(ethylene glycol) (PEG) coating or PEGylation method as a successful mode of drug delivery. Radioactive Pr2O3 was produced via a Pr(n,&ggr;)Pr reaction by thermal neutron bombardment of the prepared sample. RESULTS: There was good agreement between the reported experimental data and the data based on nuclear model calculations. In addition, a small part of nano-Pr2O3 particles remained in suspension and most of them settled out of the water. Interestingly, the PEGylated Pr2O3 nanoparticles were water dispersible. After neutron bombardment of the sample, a stable colloidal Pr2O3 was formed. CONCLUSION: The radioactive Pr2O3 decays to the stable Nd2O3. The suggested colloidal Pr2O3 as a multifunctional therapeutic agent could have dual roles in cancer treatment as a radiotherapeutic agent using nanosized Pr2O3 and as an autophagy-inducing agent using nanosized Nd2O3.

      • KCI등재

        Development of the MICROMEGAS Detector for Measuring the Energy Spectrum of Alpha Particles by using a 241Am Source

        김도윤,함철민,신재원,박태선,홍승우,Samuel Andriamonje,Yacine Kadi,Claudio Tenreiro 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.68 No.9

        We have developed MICROMEGAS (MICRO MEsh GASeous) detectors for detecting particles emitted from an 241Am standard source. The voltage applied to the ionization region of the detector is optimized for stable operation at room temperature and atmospheric pressure. The energy of particles from the 241Am source can be varied by changing the flight path of the particle from the 241Am source. The channel numbers of the experimentally-measured pulse peak positions for different energies of the particles are associated with the energies deposited by the alpha particles in the ionization region of the detector as calculated by using GEANT4 simulations; thus, the energy calibration of the MICROMEGAS detector for particles is done. For the energy calibration, the thickness of the ionization region is adjusted so that particles may completely stop in the ionization region and their kinetic energies are fully deposited in the region. The efficiency of our MICROMEGAS detector for particles under the present conditions is found to be 97.3%.

      • SCISCIESCOPUSKCI등재

        Development of the MICROMEGAS detector for measuring the energy spectrum of alpha particles by using a 241Am source

        Kim, Do Yoon,Ham, Cheolmin,Shin, Jae Won,Park, Tae-Sun,Hong, Seung-Woo,Andriamonje, Samuel,Kadi, Yacine,Tenreiro, Claudio 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol. No.

        <P>We have developed MICROMEGAS (MICRO MEsh GASeous) detectors for detecting a particles emitted from an Am-241 standard source. The voltage applied to the ionization region of the detector is optimized for stable operation at room temperature and atmospheric pressure. The energy of a particles from the Am-241 source can be varied by changing the flight path of the a particle from the Am-241 source. The channel numbers of the experimentally-measured pulse peak positions for different energies of the a particles are associated with the energies deposited by the alpha particles in the ionization region of the detector as calculated by using GEANT4 simulations; thus, the energy calibration of the MICROMEGAS detector for a particles is done. For the energy calibration, the thickness of the ionization region is adjusted so that a particles may completely stop in the ionization region and their kinetic energies are fully deposited in the region. The efficiency of our MICROMEGAS detector for a particles under the present conditions is found to be similar to 97.3%.</P>

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