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        Utilization of plastic bottle waste of polyethylene terephthalate as a low-cost membrane and its modifications for gas separation

        Badrut Tamam Ibnu Ali,Cininta Nareswari,Triyanda Gunawan,Nurul Widiastuti,Yuly Kusumawati,Juhana Jaafar,Hens Saputra,Dety Oktavia Sulistiono 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.127 No.-

        Polyethylene terephthalate (PET) is a widely used polymer in packaging products, leading to the daily disposalof millions of PET bottles as waste. 1.1 to 8.8 million tonnes of plastic waste enter the sea each year. The environmental challenge of non-biodegradable PET waste can be addressed by utilizing it as a thinlayermembrane for gas separation. This study modified the PET membrane by blending it with Pebaxpolymer and adding zeolite as a filler to enhance its performance. Characterization techniques, includingFTIR, SEM, TGA, tensile strength testing, and contact angle measurements, were performed on all modifiedmembranes. The membranes were prepared using phase inversion via immersion precipitation. Theresults showed that the PET waste membrane had a denser surface pore morphology and asymmetricalcross-sectional pores than other membranes. Adding Pebax and zeolite resulted in a more regularsponge-like pore structure. The PET, PET-Pebax, and PET-Zeolite NaY-Pebax membranes exhibited hydrophilicproperties, as indicated by contact angle values ranging from 48-78. Regarding CO2/CH4 separation,the 9% PET-Pebax membrane had the highest CO2 permeability, a 21% increase from the originalPET waste membrane. Adding zeolite to the 9% PET-Pebax membrane increased CO2 permeability to1044%.

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        Evidence of Placental Villous Inflammation and Apoptosis in Third-Trimester Symptomatic SARS-CoV-2 Maternal Infection

        Erry Gumilar Dachlan,Manggala Pasca Wardhana,Kuntaman Kuntaman,Budi Utomo,Rozi Aditya Aryananda,Salsabila Nabilah Rifdah,Ifan Ali Wafa,Almira Aulia Shahnaz,Dahlia Ningrum,Nareswari Imanadha Cininta Ma 연세대학교의과대학 2024 Yonsei medical journal Vol.65 No.4

        Purpose: In view of conflicting reports on the ability of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) to infect placental tissue, this study aimed to further evaluate the impact of inflammation and placental damage from symptomatic third trimester maternal COVID-19 infection. Materials and Methods: This case-control study included 32 placenta samples each from symptomatic COVID-19 pregnancy and normal non-COVID-19 pregnancy. The villous placental area’s inflammatory expression [angiotensin converting enzyme-2 (ACE-2), transmembrane protease serine-2 (TMPRSS2), interferon-γ (IFN-γ), interleukin-6 (IL-6), and SARS-CoV-2 spike protein] and apoptotic rate were examined using immunohistochemistry and Terminal deoxynucleotidyl transferase dUTP Nick- End La beling (TUNEL) assay. Comparison and correlation analysis were used based on COVID-19 infection, placental SARS-CoV-2 spike protein evidence, and maternal severity status. Results: Higher expressions of TMPRSS2, IFN-γ, and trophoblast apoptotic rate were observed in the COVID-19 group (p<0.001), whereas ACE-2 and IL-6 expressions were not significantly different from the control group (p>0.05). Additionally, SARS-CoV-2 spike protein was detected in 8 (25%) placental samples of COVID-19 pregnancy. COVID-19 subgroup analysis revealed in creased IFN-γ, trophoblast, and stromal apoptosis (p<0.01). Moreover, the results of the current study revealed no correlation be tween maternal COVID-19 severity and placental inflammation as well as the apoptotic process. Conclusion: The presence of SARS-CoV-2 spike protein as well as altered inflammatory and apoptotic processes may indicate the presence of placental disturbance in third-trimester maternal COVID-19 infection. The lack of correlation between placental dis ruption and maternal severity status suggests the need for more research to understand the infection process and any potential long-term impacts on all offsprings born to COVID-19-infected pregnant women.

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