일측 자골신경의 절단 및 재연결 후 흰쥐 척수에서 신경세포 접착분자(NCAM)의 면역조직반응의 변화에 관한 형태학적 연구

황세진,전복관,안동춘,조원길,김승현 대한신경과학회 1999 대한신경과학회지 Vol.17 No.1

일산화탄소 폭로후 고압산소 재폭로시 흰쥐 신장 및 심장의 SOD 활성 변동에 관한 연구

전영희,백두진,황세진,박준숙,정호삼 한양대학교 의과대학 1997 한양의대 학술지 Vol.17 No.1

Carbon monoxide is generated from the incomplete combustion of carbon-containing materials. Carbon monoxide cause muscle necrosis leading to myoglobinuria and acute renal failure. The hyperbaric oxygen exposure is increased production of active free radicals. Free radicals which promoted peroxidation of unsaturated fatty acids may destroy essential cellular components and itself cytotoxic materials. Superoxide dismutase, one of the protective mechanisms against tissue damage, catalyzed the dismutation of superoxide anion to less toxic product. The author performs the present study to investigate on Mn-SOD and Cu, Zn-SOD immunoreactivities in kidney and heart carbon monoxide (CO) and hyperbaric oxygen (HBO) exposure. The animals were divided CO exposure group, air release after CO exposure group, HBO exposure group and, CO and HBO exposure group. The specimen were sectioned in 16㎛ with cryostate. The Mn-SOD and CuZn-SOD immunohistochemistry was performed in renal corpuscle, proximal and distal convoluted tubules of kidney and, in sarcoplasm and sarcolemma of heart muscle. The results obtained were as follows: 1. The immunoreactivity of Mn-SOD were increased in renal corpuscles and distal convoluted tubules, were similar to control group in proximal convoluted tubules. 2. The immunoreactivity of Cu, Zn-SOD were increased than that of control group in renal corpuscles and distal convoluted tubules, were same that of the control group in proximal convouted tubules. 3. The immunoreactivity of Mn-SOD were increased at all experimental group of sarcoplasms of heart muscle. 4. The immunoreactivity of Cu,Zn-SOD were increased than that of control group in sarcolemma of heart muscle. These results suggest that the immunoreactivity of SOD after CO or HBO exposure is greatly increased in kidney and heart.

내연 기관의 연소실 압력 측정을 위한 자료 취득 장치의 개발

전광민,최세진,장원준 연세대학교 산업기술연구소 1990 논문집 Vol.22 No.2

This paper describes the development procedure of the data acquistion system that is user oriented. This high-speed data acquistion system can measure the normal cylinder pressure and the pressure wave caused by the knock occurence. YEDAS, the developed data acquisition system for the cylinder pressure measurement, can take about 200 cycles of the engine cylinder pressures continuously at 3000rpm. Also, YEDAS can take 16 channels of temperature measurement and can control the throttle plate. The maximum speed of the data acqusition is up to 150kHz.

이동로봇의 실시간 궤적제어

석진환,오세봉,노춘수,한성현 한국공작기계학회 2009 한국공작기계학회 춘계학술대회논문집 Vol.2009 No.-

This paper Proposes the travelling technique which is safe considerations in the collision of the obstacle in hidden range of vision information with character and in this research obstacle escape suddenly and fixed quantity in course Plans Division collision evasion control are applied. The course plan law range of vision if security from creates the course which is the possibility of moving quickly does as a favor, the speed control technique restricts the maximum speed from the foul territory and travelling which is safe possibly.

일산화탄소 및 고압산소의 폭로가 흰쥐의 제2형 폐포세포와 사구체에 미치는 영향에 관한 연구

백두진,정호삼,이계훈,황세진,전영호,전영희 한양대학교 의과대학 1997 한양의대 학술지 Vol.17 No.2

The present study was performed to investigate the ultrastructural changes of the type Ⅱ pneumocyte in the lung and that of the glomerulus in the kidney after carbon monoxide(CO) or hyperbaric oxygen (HBO) exposure. The male Sprague-Dawley rats, weighing about 200gm, were used as experimental animals. The animals were divided into CO exposure group, air exposure after CO exposure group, HBO exposure group and HBO exposure after CO exposure group. After single CO and HBO exposure (3790ppm), the specimen of lung and kidney were obtained. According to routine method, EM preparations were made and observed with electron microscope. The results obtained were as follows ; 1. Slight disruption of the mitochondrial membrane was observed in alveolar type Ⅱ pneumocyte, after single CO exposure. 2. In all experimental groups except CO exposure group, decrease in number and atropy of rough endoplasmic reticulum, disruption of double membrane and crista of mitochondria and vacuolar degeneration of lamellar bodies in alveolar type Ⅱ pneumocytes were observed. 3. In all experimental groups, fusion of the pedicles of podocytes, and obliterations of the endothelial fenestrations were observed. These results suggested that CO and HBO exposure may induced the ultrastructural damages in the alveolar type Ⅱ pneumocyte and the glomerulus.

첨단 수송장비용 센서 및 응용시스템 개발

朴世光,崔時永,全國鎭,李光萬 경북대학교 센서기술연구소 1997 연차보고서 Vol.1997 No.-

자동차의 안전성 향상과 편리성은 정밀한 기계적 시스템과 첨단 전자 시스템의 조화에 의한 것이다. 현재 자동차의 전자 시스템 중 엔진의 고효율을 위해 엔진유입 공기량, 실린더의 압력, 엔진의 회전수 등을 검출하는 센서부와 사고의 원인인 타이어 펑크를 모니터링하는 시스템이 첨단 수송 장비의 핵심 부품이다. 따라서 이를 개발하기 위해서 1) 자동차용 Air Flow Sensor, 2) 자동차용 엔진 MAP Sensor, 3) 멀터센서 모니터링 시스템, 4) 자동차 실내 환경제어용 센서시스템 개발을 위한 연구를 수행하였다. 자동차용 엔진 공기유량센서를 제작하기 위해서 유한차분법과 SPICE로 시뮬레이션을 수행하고 이 결과로 센서를 설계하였다. 센서의 저항체를 제작하기 위해서 백금박막을 제작하고 각각 조건별로 특성을 조사하여 패터닝이 잘되고 저항값이 크고 온도계수가 큰 조건을 선택하여 센서를 제작하였다. 센서는 lift-off법으로 백금을 패터닝하고 PI-2723을 보호막으로 사용하였다. 구동회로는 정온도형으로 동작하도록 피이드백 회로를 사용하였고, 기준유량계 출력과 일치하도록 피이드백 회로의 출력전압을 증폭하였다. 유체의 온도와 유량을 변화시킬 수 있는 실험장비를 제작하고 기준유량계와 제작한 유량계의 출력을 동시 측정하여 실험결과를 비교하였다. 유량에 대한 실험에서는 증폭한 출력전압은 기준유량계 출력과 거의 일치하였고, 스텝응답과 과도응답에서도 기준유량계 출력과 거의 일치함을 보았다. 자동차용 엔진 MAP Sensor의 연구에서는 SDB 웨이퍼를 이용하여 절대압 압력센서를 제조하였다. 센서의 구조는 두 개의 휫스톤 브릿지 회로와 다이아프램으로 구성되어있다. 두 개의 휫스톤 브릿지중 하나는 다이아프램의 가장자리에 위치하고, 다른 하나는 다이아프램의 가운데 부분에 위치한다. 다이아프램의 공극은 10^-5 Torr의 진공에서 형성시켜 공극안의 공기로 인한 압력센서의 감도에 미치는 온도효과를 줄였다. 이것은 압력센서의 온도보상에 대한 부수적인 방법이다. 본 실험의 주된 온도 보상법은 두 브릿지의 오프셋 전압의 차를 이용한 방법이다. 이 방법을 이용하여 22 ∼ 100℃ 범위에서 온도 영향을 80 %이상 보상할 수가 있었다. 멀티센서 모니터링 시스템 연구에서는 첨단 수송장치용에 적합한 직접 디지털 출력을 갖는 압력 센서와 온도 센서를 멀티 센서에 적합한 형태로 제작하였다. 압력 센서는 PR 희생층과 금속 구조층으로 하는 표면 마이크로머시닝 기술을 이용하여 제작하였으며, 온도 센서는 n-well CMOS 공정을 이용한 substrate PNP BJT 트랜지스터를 이용하여 제작하였다. 이 두 센서를 함께 제작할 수 있는 공정을 개발하였으며 각각소자에 대하여 측정 셋업을 구성하여 측정하였다. 직접 디지털 압력 센서의 출력에 대한 기본적인 동작 특성을 확인하였으며, 제작된 온도 센서의 감도는 1.57 ㎷/℃ 이다. 자동차 실내환경제어용 센서시스템 개발에서는 표준 CMOS 공정기술과 실리콘미세가공기술을 이용하여 자동차 실내환경 제어용 센서시스템을 개발하기 위하여 마이크로 가스유량센서와 습도센서를 설계하고 제조공정을 수행하였다. 가스유량센서의 경우 설계된 칩의 크기는 3 × 3 ㎟이고, 히터 좌우에 6 쌍의 n-poly/p-poly 열전대를 구성하였다. 습도센서의 경우 칩의 크기가 0.8 × 1.2 ㎟이고 단일 n-poly 실리콘히터로만 구성되어 있는 매우 간단한 구조를 하고 있다. 최소의 열용량과 기판 및 페케지를 통한 열손실을 최소화하기 위하여 열적 및 기계적 특성이 우수한 NON 구조의 브릿지형 다이아프램을 실리콘 미세가공 기술을 이용하여 구현하였다. 또한 NON절연막의 열전도특성을 연구하기 위한 측정소자를 설계·제작하고 그 특성을 측정 중에 있다. 마이크로 습도센서의 동작원리를 기술하고 마이크로 열센서를 구동하게 될 구동회로를 설계·검증하고 있으며 CMOS 회로화 하여 센서와 함께 집적된 센서시스템을 구현할 것이다. The improvement of safety and convenience in motor car lies on the harmony of a minute mechanical system and high-tech electric system. Nowadays the core part of the high-tech transport equipment is the system and the sensor part. The system monitors the flat tire that causes accidents and the sensor part detects the air amount of a engine intake, the pressure of the cylinder and the turn number of an engine for high efficiency of engine in car electronic system. In order to develop it, therefore we have studied 1) an air flow sensor for car engine, 2) a pressure sensor for car engine, 3) the system monitoring pressure of car tire. We designed air flow sensor in use of a finite different method and SPICE simulation to make it. In order to make resistors in the sensor, we made platinum thin film and then we tested the characteristics of the thin film in various conditions. So we chose the condition which is patterning better, higher resistor value and higher temperature coefficient. The sensor of platinum thin film was patterned by lift-off method and passivated with PI-2723. We used the feedback circuit to make an operation circuit drive in constant temperature. We amplified the output voltage of the fabricated sensor in accordance with that of a reference flowmeter. We made an equipment to change fluid temperature and flow. We measured the output of the reference flowmeter and the fabricated flow sensor simultaneously, and compared them. In the experiment, the amplified output voltage nearly agree to the output of the reference flowmeter. The absolute pressure sensor using SDB wafer has been fabricated. The structure of the sensor consists of two Wheatstone bridges and a diaphragm. One of the two Wheatstone bridges is located on the edge of diaphragm, and the other is located on the center of diaphragm. The diaphragm cavity is sealed in vacuum(∼10^-5 Torr) to reduce the effect of temperature due to the vapor in the cavity on the sensitivity of pressure sensor. This is the minor method of temperature compensation method. In this experiment the main compensation method is to use the differrence of the two bridge offset voltages. In this method the temperature effect in the range of 22 ℃ ∼ 100 ℃ was compensated over 80 %. We produced a pressure sensor and a temperature sensor, which are suitable for a multi sensor, and have the direct digital output suitable for an advanced transporting equipment. The pressure sensor was fabricated using a surface micromachining technique with a sacrificial PR layer and a structural metal layer. The temperature sensor was fabricated using a substrate PNP BJT made by use of an n-well CMOS process. We developed the process that could produce these two sensors together, organized and estimated the setup about each element. The basic operating characteristics are identified about the direct digital output of the pressure sensor, and the sensitivity of the produced temperature sensor is 1.57㎷/℃ Micro gas-flow sensor and humidity sensor were designed and fabricated using a standard CMOS process technology and silicon micromachining techniques for an Interior Environment of Automotive. The chip size of designed gas-flow sensor is 3 × 3 ㎟ with six pairs of n-poly/p-poly thermocouples around the heater. For the case of the humidity sensor, the size is 0.8 × 1.2 ㎟ with single n-poly silicon heater and simplicity. A bridge type diaphragm of NON structure having an excellent mechanical and thermal properties, was implemented by silicon anisotropic etch. The thermal properties of NON insulator is investigating using by the measurement device that was designed and made specially. The operating principle of micro humidity sensor was described and the driving circuits of the micro thermal sensors were designed and verified. The circuits in CMOS will be integrated into the sensor system with the thermal sensor.

FEM을 이용한 선삭가공 절삭조건의 영향 분석

임세환,송춘삼,홍석관,강정진,김주현 한국공작기계학회 2007 한국공작기계학회 추계학술대회논문집 Vol.2007 No.-

A plane strain finite element model is developed to simulate turning with continuous chip formation using adaptive remeshing during the thermal-mechanical coupled analysis. Comparisons between the experimental and simulation results for cutting forces are performed to validate FE analysis results. Influences of machining parameters such as depth of cut, cutting speed and feed rate on cuting force and shear angle are analyzed by Taguchi method. The more depth of cut and feed rate result in the increase of cutting forces, but the rates of increase are decrease due to the larger shear angle. As the cutting speed increases, von Mises stress of workpiece near the tool tip decreases because the strength of specimen decreases at high temperature above 500℃. This thermal effect on cutting force is negligible because the affected area is very localized and the average values of von Mises stress in the shear plane are the same among the diverse cutting parameters.

스포츠 브랜드 기업의 SNS 정보특성, 미디어 및 브랜드 인게이지먼트, 구매의도의 구조적 관계

전윤기(Yoonki Chun),이정학(Jeoung-Hak Lee),김민준(Min-Jun Kim),고세진(Se-Jin Ko) 한국사회체육학회 2023 한국사회체육학회지 Vol.- No.93

Purpose: The purpose of this study is to examine the relationship amogn sport brands’ social media information traits, media and brand engagement, and consumers’ purchase intentions. Method: The study targeted consumers who have experienced sport brands’ social media and collected data through online surveys (N=546). The surveys included 28 maesurement items. The data were analyzed using SPSS and AMOS software, and frequency, reliability ,and correlation analysis were performed. Further, confirmatory factor analysis and structural equation modeling were used to test the hypotheses. Results: First, the traits of entertainment and accessibility had a gsinificant positive effect on media engagement. Second, the quality of information trait had a signiicfant positive effect on brand engagement. Third, both the quality of information and accessibility trait shad a significant positive effect on consumers’ purchase intention. Fourth, media engagement had a positive efefct on brand engagement. Fifth, media engagement had a positive effect on purchase intention. Sixth, brand engagement had a significant positive effect on purchase intention. Seventh, the relationship between sport brands’ social media information traits and consumers’ purchase intention was mediated both indviidually and serially by media and brand engagement. Conclusion: Overall, the results of this study suggest that sport brand se’fforts in providing quality content on their social media platforms can generate positive enggaement with customers and may lead to purchase intentions. Further implications and future directions are discussed.

응급실에 내원한 약물중독환자의 지역별 비교분석

임근우,박일영,유승진,나병호,오동렬,전해명,황주일,김세경 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

We reviewed retrospectively 230 patients who came to emergency room of Kang Nam St. Mary's Hospital and Uijongbu St. Mary's Hospital between 1. January and 31. December 1994. We classified them according to their age, sex, a sort of drug, the cause of poisoning, prehospital care, time-lapse to arrive at hospital after poisoning, psychiatric problem the status of patients. *We conclude as follows; 1. The male to female ratio was totally 1 : 1.98, 1 : 1.24 in a urban area, 1 : 2.43 in a rural area. 2. On age of the patients in this study, the peake incidence was between 20 and 39(55.2%). 3. On seasonal prevalence, the poisoning was most common in summer and spring, in urban area(35.7%) and rural area(37.0%) respectively. 4. The common drug were as follow; Doxylamine, Organophosphate, Acetaminophen in urban area, Paraquat, Organophospate, Doxylamine in rural area 5. The percentage of suicidal attempt were 81.8% and 87.7% in urban area and rural area respectively. 6. The poisoning patients had psychatric problem in 19.4% and 24.6%, in urban area and rural area respectively. 7. Before arrival to emergency room, 27.7% of patient was done prehospital care in rural area. 8. On arrival to emergency room, 95.1% and 73.8% of patients show stable vital sign in urban area and rural area respectively.

사상체질론의 정신의학적 타당성에 대한 연구

민성길,김동기,박진균,전세일 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.3

연구목적 : 건간한 의대상 312명과 신경증적 장애를 가진 환자 288명을 대상으로 하였다. 사상체질의 구별은 노정우 및 김달래 두 전문가에 의한 판정, 그리고 경희의대 사상체질 설문지(QSCC Ⅱ)에 의한 판정 등 3가지 방법에 의하였다. 연구 대상에게 정신과적 증상척도(SCL-90), 체질특성척도 및 성격척도를 사용하여 자가 평가하게 하였다. 각종 척도들의 타당도와 신뢰도는 입증되었다. 이 척도들을 통계적으로 분석하고 고전적 설명과 어느 정도 일치하는 지를 검토하였다. 연구결과 : 1) 3가지 분류방법간에 차이가 컸었다. 그 중 전문가의 직접적 면담에 의한 감별보다 QSCCⅡ 설문지형이 비교적 감별력이 컸다. 3) QSCCⅡ가 감별력이 비교적 크다고 하더라도 그 결과가 소음군의 대인공포-강박증, 불면-식용상실, 무력-예민-소화기-한기-피부증후군 그리고 정력부족등 신경증적 증상과 소극-비사교적, 내향형 성격 및 이성적 성격특징 등 몇가지 특징을 감별하는 데에만 비교적 유의하였고, 태음군의 특정인 독특한 신념, 온기, 활달-사교적 성격에 대해서는 부분적으로 그 특징을 감별하였다. 또한 소양군의 활달-사교형 성격과 감정형 성격의 특징 등은 극히 부분적으로 감별하였다. 결 론 : 이러한 결과는 현존하는 사상체질 구분방법에 일치점이 결여되어 있다는 것, 각종척도를 사용한 결과는 사상체질에 관한 고전적 설명을 부분적으로만 입증하고 있다는 것, 따라서 사상체질구분에 대한 향후보다 객관적인 연구가 필요하다는 것을 시사한다. Object : This study is to examine the validity of constitutional classification of Sa-sang medical theory. This theory classifies the human constitution to 4 types according to classical oriental philosophy on yin and yang. Subjects and Method : Subjects were 312 medical students and 288 neurotic patients with diagnosis of neurotic, stress related and somatoform disorders and minor depressive episodes according to ICD-10. Medical students were classified to 4 Sa-sang Constitution Classification(QSCCⅡ). For assessmnent of symptoms and signs, Korean version of SCL-90, a constitution scale and personality scale which were designed for this study were used. These instruments were found to be reliable and valid through statistical analysis. Subjects were asked to rate these scales. The data were analysed with factor analysis and factor scores were compared among 4 Sa-sang constitutions by ANOVA and t-test. The data from patient group were analysed with factor analysis and the results were compared with the Sa-sang medical theory. Results : Results of classification by 3 ways were inconsistent showing a significant difference among them. Among them, QSCCⅡ was most reliable. In QSCC Ⅱ, only the factor scores of factors of homophobia-obsession, weakness-sensitiveness-indigestion-chillness-skin syndrome, sexual weakness, passive-unsociable personality, introverted personality and rational, personality, were significantly high in So-um (small yin) group of medical students. A factor of warmnes and active-sociable personality were significantly high in Tae-um(big yin)group. Also active-sociable and effective pesonality was partly related with So-yang(small yang)group. Conclusion : These results suggest that those present classification methods inconsistent, that these methods are proving only parts of Sa-sang medical theory, and that objective and scientific studies are needed for reliability and validity of Sa-sang medical theory.