某 製鍊業 勤勞者에 있어서 肺 換氣機能의 評價에 關한 硏究

文哲星,金光鍾,車喆煥 최신의학사 1983 最新醫學 Vol.26 No.9

Amentoflavone의 아라키돈산 유리효소인 phopholipase A_2에 대한 저해활성 및 비만세포에서 histamine 유리 억제효과

문태철,이은경,이승호,손건호,김현표,강삼식,장현욱 영남대학교 약품개발연구소 2002 영남대학교 약품개발연구소 연구업적집 Vol.11 No.-

Amentoflavone, naturally occurring biflavonid, isolated from the leaves of Ginko biloba, selectively inhibited human seceretory phospholipase A_2. This compound potently and irreversibly inhibited human group IIA in a dose dependent manner with an IC_50, about 3??M. Amentoflavone inhibited phospholipase A_2 by noncompetitive manner, with the apparent Ki value of 1×10^3M. In addition, the inhibitory activity of amentoflavone is rather specific against group IIA phospholipase A_2 than IB phospholipase A_2. Furthermore, this compound strong inhibit histamine release from A_23187 treated rat peritoneal mast cells. These results indicate naturally occurring biflavonid represents a novel anti-inflammatory agent.

제주도 주요하천의 기저유출량 산정

문덕철,양성기,고기원,박원배 한국환경과학회 2005 한국환경과학회지 Vol.14 No.4

Groundwater in Jeju Island, flowing through main stream, is spring water from underground. To set a fixed quantity of groundwater flowing from surface in a hydrological view, 4 downstream (Woedo stream, Gangjung stream, Yeonwoe stream and Ongpo stream) were selected to calculate the characteristic of baseflow and the base-flow discharge through the data on tachometry. There were 11 to 14 level peak caused by runoff, mostly occurred during monsoon season. Also, duration of runoff was 15 to 25 hours, well reflecting the characteristic of inclined, short stream length in Jeju Island and pervious hydrogeographical feature. In case of Gangjung stream, Yeonwoe stream and Ongpo stream, variation of stream water level by baseflow rose above during summer, which was closely linked to the distribution of seasonal precipitation. From autumn to spring, water level fell below while that of Woedo stream remained the same all year round. Data on the water level observed in Woedo stream and Gangjung stream in every single minutes was applied to weir formula(equation of Oki and Govinda Rao) to calculate baseflow discharge. Also, using the data on current and water level calculated in Ongpo stream and Yeonwoe stream, water level-water flow rating was applied to assess baseflow discharge.

국내 해양식물플랑크톤의 주요종과 분포에 대한 조사

문성기,최철만 한국환경과학회 2003 한국환경과학회지 Vol.12 No.7

문헌 32편에서 조사된 출현종수는 최저 43종에서 최고 200종까지 기록되고, 그 중에서 주요종수는 최저 2종에서 최고 27종까지로 종수의 기록에 상당한 차이를 보였다. 본 조사에서 기록한 주요종의 목록은 모두 50속 116종이었고, 규조류 34속 89종(76.6%), 와편모조류 11속 22종(18.9%), 황갈색조류 2속 2종(1.7%), 남조류, 라피도조류, 유글레나조류가 각각 1속 1종(0.9%)이었다. 생태적 특성을 반영하는 주요종으로서는 우점종이 Actinoptychus seranius를 비롯하여 79종, 출현빈번종이 Coscinodiscus centralis를 비롯하여 50종, 적조원인종이 Cochlodinium polykrikoides를 비롯한 36종이었다. 또한 3가지의 주요특성을 모두 지닌 종은 Prorocenfrum micans를 비롯한 11종이었다. 여러 문헌에서 주요종으로 언급했던 종은 규조류인 Skeletonema costatum이었고 단일 속(genus)으로서 18종의 많은 종이 조사된 속은 Chαetoceros속이었다. This survey was carried out to assess important species of phytoplankton in the ocean and bay in Korea from 32 references. The number of important species assessed from 50 genera 116 species. Of them, Bacillariophycea (diatoms) 34 genera 89 speceis(76.6%), Dinophyceae(dinoflagellates) 11 genera 22 species(18.9%), Chrysophyceae 2 genera 2 species(1.7%), Cyanophycea(blue-green algae), Raphidophyceae, Euglenophyceae(euglenoids) 1 genera 1 species(0.9%) respectively. By ecological characters, the number of dominant species were 79 species including Actinoptychus seranius, 50 species including Coscinodiscus centralis were recorded as frequently apperaing species and 36 species including Cochlodinium polykrikoides were recorded as red-tide causative organism. Also, 11 species including Prorocentrum micans were surveyed as the indicator including all ecological characters.

한국무용 전공자의 근 기능 특성 연구

문성철,백연옥 仁荷大學校 스포츠科學硏究所 2001 論文集 Vol.13 No.-

The purpose of this study was to find the trait on the muscle strength, power and endurance of Korean dancer in high school. 16 subjects of high school dancer(Korean dancer; 8, ballerina; 8) were recruited randomly for this experimental study. All subjects were healthy dancers with out acute or chronic injuries. Subjects were tested for knee extension and flexion, ankle extension and flexion on a Cybex-II isokinetic dynamometer of made Lumex Co. in U.S.A. The results of analysis on the data obtained from each measurement were as follows: 1.The trait of muscle strength of Korean dancer was showed to higher deficit of peak torque for knee flexion between left and right, to higher peak torque(peak torque/weight ratio) for left knee extension, to higher peak torque of left ankle flexion(peak torque/weight ratio), to lower deficit of peak torque for ankle flexion between left and right, to lower peak torque of left ankle extension(peak torque/weight ratio) and the right ankle peak torque/weight ratio, and to higher left ankle ipsilateral balance. 2.The trait of muscle power of Korean dancer was showed to higher deficit of peak torque for knee flexion power between left and right, to higher peak torque(peak torque/weight ratio) for left knee extension power, to lower deficit of peak torque for knee extension power between left and right, to higher left ankle flexion power (peak torque/weight ratio), to lower left ankle extension power(peak torque/weight ratio), and to higher deficit of peak torque for ankle extension power between left and right. 3.The trait of muscle endurance of Korean dancer was showed to higher peak torque for left knee extension endurance.

댐과 호수의 식물플랑크톤에 대한 주요종의 사정

문성기,최철만 慶星大學校 1998 論文集 Vol.19 No.2

This survey was carried out to assess important species of phytoplankton in Dam and Lake from 29 references. The results are as follows. 1. The number of important species assessed from 59 classes 7 orders 11 families 15 genera. 2. Of them, Bacillariphyceae were 17 kinds, Chlorophyceae 4 kinds, Cyanophyceae 3 kind, Dinophyceae 1 kind. 3. By ecological characters, the number of dominant species were 23 kinds, cosmopolitic species 11 frequently occurrence species 19, pollution indicator species 2(Microcystis aeruginosa, Achnanthes minutissima), blooming causative species 2)Fragilaria crotonensis, Melosira italica).

치아 마모 환자에서 수직고경 증가를 동반하여 단일구조 지르코니아 보철물로 완전구강회복을 시행한 증례

오경철,정문규,김지환,심준성 大韓齒科補綴學會 2012 대한치과보철학회지 Vol.50 No.3

과도한 치아 마모는 교합면에 손상을 야기하고, 치수 병변, 교합 부조화, 기능장애, 심미적 문제 등을 야기할 수 있다. 과도한 치아 마모를 갖고 있는 환자들을 치료하고자 할 때 수직교합고경(vertical dimension of occlusion, VDO)의 상실 여부와 수복을 위한 악간 공간의 적절성 여부에 기반하여 분류를 할 필요가 있다. 본 증례의 환자는 다수 치아들의 마모를 지닌 50세의 남성으로, 과도한 치아 마모가 있지만 수직교합고경의 상실은 없으며 수복을 위한 악간 공간이 부족하였다. 이러한 경우 수직교합고경을 증가시켜 치료를 진행하는 것을 고려할 수 있다. 수직교합고경의 증가를 필요한 범위 내에서 최소로 줄이고, 증가된 수직교합고경 상에서 안정화 기간을 거친 뒤 안정된 교합 접촉을 제공할 수 있다면, 수직고경 증가를 동반한 치료법은 안정성을 가질 수 있다. 본 남성 환자를 치료하기 위해 수직고경의 증가를 동반하여 전치부와 구치부에서 단일 구조 지르코니아를 이용한 고정성 보철물로 수복을 하였다. 일련의 치료과정을 통하여 기능적인 면과 심미적인 면에서 만족스러운 결과를 얻었기에 보고하는 바이다. Excessive occlusal wear results in unacceptable damage to the occluding surfaces, and can cause pulpal injury, occlusal disharmony, impaired function, and aesthetic deformity. Patients with severely worn dentition need to be classified as several categories relative to the vertical dimension of occlusion (VDO) and the interocclusal distance for the prosthetic space. When treating patients classified as those who have excessive wear without loss of occlusal vertical dimension but with limited space, we could consider treating them at an increased vertical dimension of occlusion. Treatments at an increased vertical dimension of occlusion may provide stability, given that the amount of its increase was minimal, and a perfected occlusion was achieved after enough stabilization period. A 50-year-old male visited the department of Prosthodontics in Yonsei University Dental Hospital with the chief complaint of worn teeth on lower anterior area. Reconstruction at an increased vertical dimension of occlusion was planned. After the compatibility of the new vertical dimension of occlusion had been confirmed under interim fixed restorations, definitive fixed restorations composed of full-contour monolithic zirconia prostheses were placed. This case presents that a satisfactory clinical result was achieved by restoring the worn dentition at an increased vertical dimension of occlusion with an improvement in esthetics and function.

여성 복압성요실금에 대한 Tension-free Vaginal Tape(TVT) 수술 성적

문찬,강윤일,김경영,문형윤,노준,김철성 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

Background: We wanted to evaluated the long term results of the tension-free vaginal tape (TVT) Procedure for treating strss urinary incontinence in women. Method: During Octover 1, 1998 to December 31, 2005, we evaluated the 52 women who underwent the TVT procedure for stress urinary incontinence at least 1 year following surgery. Preoperatively, Patients were evaluated with history taking, Physical examinations and urodynamic study, Operation and hospitalization data were evaluated with duration of procedure, hospital days, foley catheter removal days and use of analgesics, Postoperative evaluations included the uroflowmetry, residual urine volume, surgical outcomes, complications and patients' satisfaction with the procedure. Results: The follow-up period was a mean of 16 months. Preoperative I-QoL total score was 58.0. Comparision the result between preoperative and postoperative Q max was significantly shoter in the postoperative result. TVT procedure remained cure in 96.2% (cured: 82.7%, improved: 13.5%) and successful in 96.1%. Also, 49(94.2%) Patients would like to recommended the TVT procedure to others. There was no serious or long-term complications, Conclusions: The TVT procedure appear to be effective and safe for the surgical treatment of female stress urinary incontinence and showed a good long-term cure rate.

노인외상환자의 예후 인자

문철규,전정민,최성혁,문준동,이성우,홍윤식 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Background: It has been documented that certain prognostic factors may affect the outcomes of the old aged victims by trauma. Considering that trauma is the sixth most common cause of death in people over the age of 65 years and there is a rapid growth of elderly population, it is paramount to understand the prognostic factors when dealing with geriatric trauma patients. Hypothesis and Goals: It can be hypothesized that the prognostic factors should be determined independently between populations being consisted of different races, countries, socio-economic states, cultures, or so on. Thus, the study was designed to evaluate the factors affecting the outcomes of elderly Korean trauma patients. Methods: One hundred forty six patients aged over 65 years were retrospectively reviewed, who visited the Emergency Center of Korea University from January, 1997 to June, 1998. Of 146 patients, 7 were excluded due to discharge against advice or transfer to the other hospitals. Parameters analyzed were age, sex, mechanism of injuries, body region injured, Injury Severity Score (ISS), previous medical illness, hospital morbidity, duration of hospital stay, and cost. Each patient was classified into improved or not-improved group depending on the outcomes, and young-old or old-old group depending on the age. The factors affecting the hospital stay in improved patients were analyzed in the parameters of previous medical illness, hospital morbidity, multiple injuries, ISS, and age. All statistical tests were conducted with two-tailed levels of 0.05. Results: Of 139 patients, the mean age was 74±7.1 years, mean ISS 9.3±7.26, mean hospital stay 27±27.1 days. Most commonly injured body region was the extremities due to fall from a level surface. Rate of previous illness showed 0.94 medical diseases per person and were aggravated after trauma in 39 patients (60.9%). Hospital morbidity rate was 0.46 incidents per person. There were no differences in age and duration of hospital stay between the improved and the not-improved group. Substantial differences were noted in affected body region, incidence of previous illness, and hospital morbidity between the groups (p=NS). Not-improved group had higher ISS(p<0.05). ISS, previous illness and hospital morbidity affected the duration of hospital stay in the improved group. Hospital stay was 40±25.1 days in patients with ISS over 6 while 6±8.6 days in those with ISS 5(p<0.05). Hospital stay in the improved was 26±26.9 days while 31±24.8 days in the improved old-old group (p=NS). Hospital stay in the young-old minor trauma (ISS5) patients with previous illness and hospital morbidity was 26±10.1 days while 4±7.3 days in those without previous illness and hospital morbidity (p<0.05). Conclusion: Previous medical illness and hospital morbidity, not age, are predictive of outcomes of geriatric trauma patients with respect to hospital stay. As most of the hospital morbidity was a trauma-induced aggravation of previous medical illness and hospital morbidity contributing poor outcomes can be potentially avoidable, routine aggressive care for the geriatric trauma patients with previous medical illnesses is needed.

歷代醫家들의 升降論에 對한 文獻的 考察

文聖喆,金聖勳 대한동의병리학회 1997 동의생리병리학회지 Vol.11 No.1

宇宙萬物의 運動形式이며, 人體에서도 陰陽五行學說과 더불어 生命活動을 營爲하는 基本原理로 認識되고 있는 升降論에 대하여 《黃帝內徑》중에 升降과 關係있는 原文을 중심으로 升降의 槪念을 考察하고, 歷代醫家들의 說을 宋以前, 金元代, 明代, 淸代로 區分하여 學派를 不問하고 升降學說과 有關한 說을 中心으로 比較, 檢討하였다. Through the bibliographical on the Seungang, ascending & descending theory of ancient medical scholars for many generations, the results are obtained as follows: 1. In Huang Ti Nei Ching(黃帝內經), the concept of Seunggang was formed into a systemic medical theory, the basic pattern of motions of everything in universe, and also classified as Seunggang of clear yang and turbid yin, Seunggang of bowel and viscera, Seunggang of herbal medicine. The pathology of Seunggang, and its treatment were explained in detail, too. 2. Before the Song(宋) dynasty, HwaTa(華陀) Zhang Zhong jing(張仲景), So WonBang(巢元方), Wang Do(王燾) argued about the ascending & descending of various disease on the basis of the NeiChing. 3. In Kum-Won(金元) dynasty, Li Dong Won(李東垣), ones of four great doctors thought spleen and stomach as the main axis of ascending & descending movement, and emphasized supplementing digestive tract and activating yang as chief treating methods. Zhu Danxi perceived the theory that Yang often in excess. Yin often in shortage, and he emphasized the treating method of nourishing Yin and relieving fire. 4. In Myong dynasty, Wang Lyun(王綸) emphasized the treating method of supplying Qi and nourishing Yin on the basis of the theory of Donghen(東垣), Danxi(丹溪). Li Shi Jin(李時珍) expatiated the QiMei, Sunggang of medical herbs on the basis of the theory of Neiching, Zhang Won SO(張元素), ZhangKeBin(張介賓), taking a serious view of ascending of priniordial Yang in vital portal, presented the theory of QiChil that bulids up the foundation of SungGang of five parenchymatous viscera. 5. In Ching dynasty, the theory of Sunggang was developed on the point of view of bowel and viscera Whang Won Er(黃元御) insisted the theory of left ascending & right descending, and explained the Sunggang of five element and five parenchymatous viscera through classifying the middle Qi into four grade, half ascending, ascending, half descending, descending. Ha Mong Yo(何夢瑤) presented the SungGang of five parenchymatous viscera. Yie Tianshi(葉天士) developed the theory of the spleen & stomach on Myong dynasty. and established the treatment of TongKangWeTak(通降胃濁法) by classifying the SungGang of spleen & stomach. Wu Ju Tong(吳鞠通) presented the treatment of ascending & descending, according to the demonstration of triple heater. Dang Yong Chun(唐容川) took a serious view of the SungGang of Qi & Blood. Suk Su Dang(石壽棠) asserted the theory of dryness & dampness and he regarded maintaining the blance of dryness & dampness. As the method of maintaining to balance of ascending & descending. Zhang Suk Soon(張錫純) emphasized the function of the atmosphere succesing the theory of Yu Ka Un(喩嘉言). Tu Hak Hae(調學海), one who made final settlement of the theory of SungGang, made overall presentation about the SungGang, and criticized the theory of left ascending & right descending. He also insisted that SungGang must be divided to inside and outside.