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- 저자 : Christian Killer (검색결과 2 건)
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Slaven Pikija,Vladimir Trkulja,Christian Ramesmayer,Johannes S. Mutzenbach,Monika Killer-Oberpfalzer,Constantin Hecker,Nele Bubel,Michael Ulrich Füssel,Johann Sellner 대한뇌졸중학회 2018 Journal of stroke Vol.20 No.3
Background and Purpose Reports investigating the relationship between in-procedure blood pressure (BP) and outcomes in patients undergoing endovascular thrombectomy (EVT) due to anterior circulation stroke are sparse and contradictory. Methods Consecutive EVT-treated adults (modern stent retrievers, BP managed in line with the recommendations, general anesthesia, invasive BP measurements) were evaluated for associations of the rate of in-procedure systolic BP (SBP) and mean arterial pressure (MAP) excursions to >120%/<80% of the reference values (serial measurements at anesthesia induction) and of the reference BP/weighted in-procedure mean BP with post-procedure imaging outcomes (ischemic lesion volume [ILV], hemorrhages) and 3-month functional outcome (modified Rankin Scale [mRS], score 0 to 2 vs. 3 to 6). Results Overall 164 patients (70.7% pharmacological reperfusion, 80.5% with good collaterals, 73.8% with successful reperfusion) were evaluated for ILV (range, 0 to 581 cm3) and hemorrhages (incidence 17.7%). Higher rate of in-procedure SBP/MAP excursions to >120% was independently associated with lower ILV, while higher in-procedure mean SBP/MAP was associated with lower odds of hemorrhages. mRS 0-2 was achieved in 75/155 (48.4%) evaluated patients (nine had missing mRS data). Higher rate of SBP/MAP excursions to >120% and higher reference SBP/MAP were independently associated with higher odds of mRS 0-2, while higher ILV was associated with lower odds of mRS 0-2. Rate of SBP/MAP excursions to <80% was not associated with any outcome. Conclusions In the EVT-treated patients with BP managed within the recommended limits, a better functional outcome might be achieved by targeting in-procedure BP that exceeds the preprocedure values by more than 20%.
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WeTrace: a Privacy-preserving Tracing Approach
Muriel Franco,Bruno Rodrigues,Christian Killer,Eder John Scheid,Alessandro De Carli,Andreas Gassmann,David Schönbächler,Burkhard Stiller 한국통신학회 2021 Journal of communications and networks Vol.23 No.5
For the protection of people and society against harmand health threats—especially in case of the COVID-19 pandemic— a variety of different disciplines needs to be involved. The datacollection of basic and health-related data of individuals in today’shighly mobile society does help to plan, protect, and identify nextsteps health authorities and governments can, shall, or need to planfor or even implement. Thus, every individual, human, and inhabitantof the world is the key player—very different from many pastcrises’. And since all individuals are involved his/her (a) health and(b) privacy shall be considered in a very carefully crafted balance,not overruling one aspect with another one. Privacy remains key. The solution of the current pandemic’s data collection can bebased on a fully privacy-preserving application, which can be usedby individuals on their mobile devices, such as smartphones, whilemaintaining at the same time their privacy. Additionally, respectivedata collected in such a fully distributed setting does help to confinethe pandemic and can be achieved in a democratic and very open,but still and especially privacy-protecting manner. Therefore, the WeTrace approach and application designed utilizesthe Bluetooth low energy (BLE) communication channel,many modern mobile devices offer, where public-key cryptographyis being applied to allow for deciphering of messages for that destinationit had been intended for. Since literally every other potentialparticipant only listens to random data, even a brute force attackwill not succeed. WeTrace and its Open Source implementation ensurethat any receiver of a message knows that this is for him/her,without being able to identify the original sender.
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