Optimal Parenthesization 동적 프로그래밍의 고속처리를 위한 시스토릭 어레이의 설계

우종호,신동석,성기택 釜山水産大學校 1990 釜山水産大學 硏究報告 Vol.30 No.1-2

An 1-dimensional systolic array for optimal parenthesization dynamic programming processing is designed. To get an 1-dimensional systolic array, 2-dimensional systolic array was projected and the time scheduling was done using the block pipeline time of 2-dimensional array. The designed 1-dimensional systolic array has n processing elements. [(n+1)/2](n-1)+3n-1 processing time, only the unidirectional paths, and constant�/O channels independent upon the problem size(n is the problem size). The ratio of its processor utilization to that of 2-dimensional array is (2n�+n-1)(n�+5n-4).

우리나라에서 분리되는 Haemophilus influenzae의 9종 항균제에 대한 시험관내 감수성

장우현,최명식,석종성,정윤섭,서진태 대한화학요법학회 1989 대한화학요법학회지 Vol.7 No.2

To assess the occurrence of antimicrobial resistance among clinical isolates of H. influenzae in Korea, a total of 238 isolates were tested for their in vitro susceptibitlity to ampicillin and cefaclor by disc diffusion and 105 isolates were tested against nine antimicrobial agents-by the agar dilution method recommended by NCCLS. The antimicrobial agents sued for testing were ampicillin (Sigma A-9518, U.S.S.), cefaclor (Daewoong Lilly, Korea), cephalexin (Sigma C-4895, U.S.A.), cephradine (Sigma C-8395, U.S.A.), cephalothin (Sigma C-4520, U.S.A.), cefadroxil (Sigma C-7020, U.S.A.), erythromycin (Sigma E-6376, U.S.A.), teracycline (Sigma T-3383, U.S.A.) and cefatrizine (Dong-A Pharmaceutical Co., Korea). The isolation rate of H. influenzae from various clinical samples was 18.9%. Using the disc diffusion test, the resisant rates to ampicillin and cefaclor were shown to be 21.9% and 3.4%, respectively. Among the 52 ampicillin-resistant strains, 42 were susceptible to cefaclor (80.8%), and only two strains wre resistant. The MIS_(s) of ampicillin ranged from <0.125 ㎍/㎖ to >128 ㎍/㎖, and its MIC_(90) was 1 ㎍/㎖. Ampicillin showed the lowst MIC_(90) among the tested antivicrobial agents. The MIC_(90) of the tested cephalosporins ranged from 9.2㎍/㎖ to > 128. Among them, cefaclor showed the lowest MIC_(90) and its MIC_(90) was 9.2 ㎍/㎖. The MIC_(90) of tetracycline and erythromycin were 2.5 ㎍/㎖ and 14.4 ㎍/㎖, respectively. By the MIC, the resistant for ampicillin, cefalor, cephalexin, cephracine, cephalothin, cefadroxil, erythromycin, tetracycline and cefatrizine were 9.5%, 1.9%, 61.9%, 76.2%, 3.8%, 68.6%, 65.7%, 13.3% and 5.7%, respectively. There was no evidence that the MIC_(s) of cefaclor for the ampicillin-resistant strains differed significantly from those of cefaclor obtained with the ampicillin-susceptible strains. Except two islates, all of the multiple-esistant strains of H. influenzae were suceptible to cefaclor.

다발성 대장암 간전이 환자의 간절제를 위한 새로운 시도

주종우,김형철,임철완,신응진,조규석,유기원,송옥평,홍대식,박성진,조준희,이혜경,김희경,권계원,고은석 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Multiple bilobar liver matastases (MBLM) are the main cause of low resectability in the colon cancer liver metastases. The authors experienced one case of initially non-resectable colon cancer liver metastases. He was curatively and safely treated with a two-stage hepatectomy using the new method of future remnant liver volume growing. A 54-year-old man was referred to our department with the sigmoid colon cancer combined with MBLM, which were checked in two small metastatic lesions in the left lobe and five large sized lesions in the right lobe in the computed tomogram (CT). A laparoscopic assisted anterior resection was primarily performed. We performed the 1^(st) stage hepatectomy 3 weeks after the colon resection. Intra-operative Ultrasonogram (US) found 9 small superficial metastatic lesions in the left lobe. All that lesions were completely removed by non-anatomical wedge resection. An occlusion ballon catheter was placed in the right portal vein through a small branch of the inferior mesenteric vein at that time. The future remnant liver volume was sufficiently increased 3 weeks after the 1^(st) hepatectomy. A right hepatectomy was safely performed 22 days after the 1^(st) hepatectomy. The patient received a regional chemotherapy (interleukin2 based immuno-chemotherapy through hepatic artery) for 4 months, then received 9 cycles of systemic chemotherapy (biweekly Oxaliplation, leucovorin, plus 5-fluorouracil) without any recurrence evidence.

40ㆍ50대 일부 남성근로자의 골감소증 및 골다공증 유병실태와 위험요인

장윤균,서현주,진영우,정미선,성숙희,박두용,김종순,김수근 大韓産業醫學會 2006 대한직업환경의학회지 Vol.18 No.2

목적: 최근 국내에서도 골다공증과 관련된 생활양식의 규명에 관한 연구가 이루어지고 있으나, 아직까지 남성 골다공증에 대한 연구가 활발하게 이루어지지 않아 40, 50대 남성근로자를 대상으로 유병률을 파악하고, 골감소증 및 골다공증 관련 위험요인을 확인하고자 하였다. 방법: 원자력발전소에 근무하는 40, 50대 남성 근로자 2,073명을 대상으로 2004년 3월~7월 기간동안 생활습관을 파악하기 위하여 자기기입식 전산입력 방식으로 최종학력, 흡연여부, 음주여부, 신체활동 횟수를 조사하였고, 골밀도검사, 체성분검사(체지방률, 허리-엉덩이둘레비), 신체계측(신장, 체중)을 시행하였고, 골밀도 검사는 Osteosys사의 EXE-3000을 이용하여 종골부위를 측정하였고, 체지방률, 허리-엉덩이 둘레비는 Biospace사의 Inbody 3.0을 이용하여 측정하였다. 통계분석은 골감소증 및 골다공증의 관련요인을 분석하기 위해 다중로지스틱회귀분석을 시행하였다. 결과: 연구대상자의 골감소증 및 골다공증 유병률은 22.8%와 3.0%이었으며, 골감소증 및 골다공증의 관련요인으로는 연령이 증가할수록, 흡연자이거나 과거흡연자일 경우, 체질량지수가 25 kg/m^(2) 미만일 경우, 30분 이상 신체활동 횟수가 주 3회 미만일 경우가 유의한 연관성이 있었다. 결론: 성인 남성 40, 50대의 골감소증 및 골다공증의 유병률이 높은 편이었으며, 골감소증 및 골다공증으로 이환을 예방하기 위하여 금연, 활발한 신체활동을 촉진하여 골밀도를 개선시키는 생활습관으로의 변화를 권고해야 할 것이다. Objective: This study was conducted to investigate the prevalence and risk factors of osteopenia and osteoporosis in 40-59 year-old male workers working at nuclear power plants. Methods: Bone density, body composition, and anthropometry data were analyzed for 2,073 subjects were carried out from March 2004 to July, 2004. Educational level, smoking status, drinking status and frequency of physical activity were investigated by self-reported questionnaires through internet to identify lifestyles related to bone mass density. Bone mass density was measured by EXE-3000 of Osteosys Co. And body fat percentage, and waist-to-hip ratio by inbody 3.0 of Biospace Co. Results: The prevalence of ostepeniaosteopenia and osteoporosis was 22.8% and 3.0%, respectively. According to multinominal multinomial logistic regression analysis, age, smoking status (current smoker and former smoker), low body mass index (< 25kg/m^(2)), and frequency of physical activity were significantly associated with osteopenia and osteoporosis. Conclusions: The prevalence of ostcopenia and osteoporosis wasseemed high for the, when it was inferred from subjects' age compared to the results of previous studies. The This study results suggeststhat it is necessary for 40-59 year-old male workers to stop smoking, and exercise regularly in order to prevent osteopenia and osteoporosis.

Role of CD4+CD25high+FOXP3+ Regulatory T Cells in Psoriasis

( Woo Jin Yun ),( Deok Woo Lee ),( Sung Eun Chang ),( Ghil Suk Yoon ),( Joo Ryung Huh ),( Chong Hyun Won ),( Mi Woo Lee ),( Sung Eun Kim ),( Beom Joon Kim ),( Kee Chan Moon ),( Jee Ho Choi ) 대한피부과학회 2010 Annals of Dermatology Vol.22 No.4

Background: CD4+CD25high+regulatory T cells (Tregs) are considered to be of vital importance for maintaining immunologic self-tolerance and preventing autoimmune diseases. These cells have been found to be deficient in skin lesions and in the peripheral blood of patients with psoriasis. Objective: To investigate the role of Tregs in the pathogenesis of psoriasis and to evaluate the changes in Tregs in relation to the severity and the clinical course of psoriasis. Methods: Immunohistochemistry (CD3, 4, 8, 79 and FOXP3) was performed in 22 psoriatic patients compared to 5 normal controls. Flow cytometry (CD3, 4, 8, 25 and FOXP3) was performed in 18 psoriatic patients and 8 normal volunteers and reverse transcriptase polymerase chain reaction (foxp3 mRNA) was performed in 8 psoriasis patients. Results: An increase in the FOXP3+ cell fraction was detected in the lesional psoriatic skin irrespective of the severity of psoriasis as compared with the normal skin. However, a decrease in FOXP3+ cells was observed in the samples obtained from psoriasis of `acute course`. FOXP3+ Treg populations in the blood of the `acute course` psoriasis was not different compared to that of `chronic course` psoriasis and normal controls. Conclusion: The deficiency of FOXP3+ Tregs in the lesional psoriatic skin might be responsible for the exacerbation of psoriasis. (Ann Dermatol 22(4) 397~403, 2010)

담도내 종양전을 동반한 간세포암

주종우(Chong-Woo Chu),김형철(Hyung-Cheol Kim),임철완(Cheol-Wan Lim),신응진(Eung-Jin Shin),조규석(Gyu-Suk Cho),류기원(Ki-Won Yu),이효원(Hyo-Won Lee),송옥평(Ok-Pyung Song),문종호(Jong-Ho Moon),고은석(Eun-Suk Koh),권계원(Kye-Won Kwon) 대한외과학회 2005 Annals of Surgical Treatment and Research(ASRT) Vol.68 No.3

강원도 춘천시 근교의 산지계류에 형성된 계단상 하상구조의 특징

김석우 ( Suk Woo Kim ),전근우 ( Kun Woo Chun ),박종민 ( Chong Min Park ),남수연 ( Soo Youn Nam ),임영협 ( Young Hyup Lim ),김영설 ( Young Seol Kim ) 한국임학회 2011 한국산림과학회지 Vol.100 No.2

강원도 춘천시 근교의 강원대학교 산림환경과학대학 학술림 내의 산지계류를 대상으로 계단상 하상구조의 기하학적 특성과 이에 대한 계류 지형인자들과의 관계를 분석하였다. 조사구간에 형성된 스텝의 간격, 높이 및 낙차의 평균값은 각각 4.69 m, 0.47 m 및 0.71 m, 스텝의 구성입경은 평균 0.68 m, 스텝의 형성개수는 100 m당 평균 21개인 것으로 나타났다. 스텝의 간격은 하폭대비 약 0.5로 선행연구들에 비해 작은 것으로 나타났으며, 스텝의 기울기는 평균 0.13이었다. 스텝의 각 기하학적 특성과 하폭과의 사이에는 모두 상관관계가 존재하지 않았으나, 스텝의 간격과 높이는 하상경사와 각각 부·정의 상관관계를 나타내었다. 또한 스텝의 기울기는 하상경사와 정의 상관을 보였고, 하상경사와의 비가 1.2로 나타나 유수에 대한 최대저항조건을 만족하며 비교적 안정상태를 유지하고 있는 것으로 나타났다. 특히 하상경사는 계단상 하상구조의 기하학적 형상(스텝의 낙차와 높이의 비)에 영향을 미치는 것으로 나타났다. 한편 스텝의 간격과 낙차는 거석의 입경과 모두 정의 상관관계를 보였다. 이러한 결과들로부터 계단상하상구조의 동태는 산지계류의 물리·생태적 환경에 큰 영향을 미칠 것으로 판단되며, 산지가 대부분인 우리나라의 계류관리에 있어서 특히 중요하게 인식되어야 할 것이다. The geometric characteristics of step-pool structures and how they are influenced by channel characteristics were investigated in a steep mountain stream in the Experimental Forests of Kangwon National University in Chuncheon, Gangwon-do. Average values of steps for the study reaches were as follows: step spacing, 4.69 m; step height, 0.47 m; step drop, 0.71 m; step-forming particle sizes, 0.68 m; number, 21steps/ 100 m; the ratio of step spacing to channel width, 0.5; and step steepness, 0.13. Relationships between spacing and height of steps and channel gradient showed a negative- and positive correlation, respectively, whereas all geometric variables of steps manifested poor correlation with channel width. Therefore, step steepness, expressed as the ratio of step height to step spacing, increased as channel gradient increased. The ratio of step steepness to channel gradient representing the criterion of maximum flow resistance was 1.2, indicating the channel bed`s stable condition. In particular, the relationship between the ratio of step drop to step height and channel gradient showed a significant negative correlation, suggesting the influence of step-pool geometry in trapping sediment and providing an aquatic habitat. Positive correlations also exist between spacing and drop of steps and step particles. Our findings suggest that the dynamics of step-pool structures may strongly control physical and ecological environments in steep mountain streams, so understanding them is essential for stream management.

탄성 표면파를 이용한 점도 센서의 개발

정우석 ( Woo Suk Chong ),김기범 ( Gi Beum Kim ),강형섭 ( Hyung Sub Kang ),홍철운 ( Chul Un Hong ) 한국센서학회 2008 센서학회지 Vol.17 No.4

색채 조명 자극이 인지기능에 미치는 영향에 관한 연구

정우석(Woo Suk Chong),유미(Mi Yu),권대규(Tae Kyu Kwon),김남균(Nam Gyun Kim) Korean Society for Precision Engineering 2007 한국정밀공학회지 Vol.24 No.10

색채 조명 자극에 대한 인체 반응에 관한 연구

정우석 ( Woo Suk Chong ),홍철운 ( Chul Un Hong ),김남균 ( Nam Gyun Kim ) 한국감성과학회 2004 감성과학 Vol.7 No.4