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ALGORITHM FOR THE CONSTRUCTION OF THE STATE TRANSITION DIAGRAM OF A SACA OVER GF($2^p$)
Choi, Un-Sook,Cho, Sung-Jin The Korean Society for Computational and Applied M 2009 Journal of applied mathematics & informatics Vol.27 No.5
In this paper, we analyze the behavior of the state transition of nongroup CA with a single attractor over GF($2^p$)(p > 1), and propose the algorithm for the construction of the state transition diagram of a Single Attractor CA(SACA) over GF($2^p$) which is very different from the construction algorithm for the state transition diagram of GF(2) SACA.
Choi, Myung-Sook,Jung, Un Ju,Kim, Hye-Jin,Do, Gyeong-Min,Jeon, Seon-Min,Kim, Myung-Joo,Lee, Mi-Kyung Institute for Advanced Research in Asian Science a 2008 The American journal of Chinese medicine Vol.36 No.1
<P>This study examined the effect of a Du-zhong (Eucommia ulmoides Oliver) leaf extract (0.175 g/100 g diet) that was supplemented with a high-fat diet (10% coconut oil, 0.2% cholesterol, wt/wt) on hyperlipidemic hamsters. Hamsters fed with Du-zhong leaf extract for 10 weeks showed a smaller size of epididymal adipocytes compared to the control group. The supplementation of the Du-zhong leaf extract significantly lowered the plasma levels of triglyceride, total cholesterol, LDL-cholesterol, non HDL-cholesterol, and free fatty acid, whereas it elevated the HDL-cholesterol/total cholesterol ratio and apolipoprotein A-I levels. The hepatic cholesterol concentration was lower in the Du-zhong group than in the control group. The plasma total cholesterol concentration was positively correlated with hepatic HMG-CoA reductase activity (r = 0.547, p < 0.05) and hepatic cholesterol concentration (r = 0.769, p < 0.001). The hepatic fatty acid synthase and HMG-CoA reductase activities were significantly lowered by a Du-zhong leaf extract supplement in high fat-fed hamsters. Hepatic fatty acid synthase activity was positively correlated with plasma fatty acid concentration (r = 0.513, p < 0.05) that was lower in the Du-zhong group. These results demonstrate that the Du-zhong leaf extract exhibits antihyperlipidemic properties by suppressing hepatic fatty acid and cholesterol biosynthesis with the simultaneous reduction of plasma and hepatic lipids in high fat-fed hamsters.</P>
Medical Image Verification Watermarking for Healthcare Information Management
Choi, Un-Sook,Lee, Suk-Hwan,Kwon, Ki-Ryong Korea Multimedia Society 2017 The journal of multimedia information system Vol.4 No.4
This paper presents a verification watermarking applied to healthcare information management. The proposed method uses the whole region based on the public-key cryptograph, which is transformed by the DWT transform to integrity verification. Furthermore, the public-key cryptograph algorithm is used for the embedded watermark image. We adaptively select the upper bit-plane including the LSB parts of each block when the watermark is inserted.
Choi, Myung-Sook,Lee, Mi-Kyung,Jung, Un Ju,Kim, Hye-Jin,Do, Geoyng-Min,Park, Yong Bok,Jeon, Seon-Min WILEY-VCH Verlag 2009 Molecular Nutrition & Food Research (Print) Vol.53 No.6
<P>This study was performed to investigate the lipid-lowering, antioxidant, and hepato-protective effects of pinitol in dose-dependent manners in hamsters fed-high fat and high cholesterol (HFHC) diet. Pinitol supplementation (0.05%, P-I and 0.1% pinitol, P-II) with an HFHC diet (10% coconut oil plus 0.2% cholesterol) for 10 wks significantly lowered the white adipose tissue weights, hepatic lipid droplets, plasma glucose, total-cholesterol, nonHDL-cholesterol, total-cholesterol/HDL-cholesterol ratio, and hepatic lipid levels. Whereas it significantly increased the brown adipose tissue weight, plasma HDL-cholesterol, apolipoprotein A-I (apo A-I) concentrations, paraoxonase (PON) activity, and/or mRNA expression, compared to the HFHC control group. Plasma insulin and adiponectin levels were significantly lower and higher, respectively, in both P-I and P-II groups than the HFHC control group. Dietary pinitol significantly inhibited hepatic HMG-CoA reductase, acyl-CoA:cholesterol acyltransferase (ACAT), and cytochrome P4502E1 (CYP2E1) activities without altering their mRNA expressions compared to the control group. Pinitol significantly elevated the hepatic antioxidant enzyme activities, whereas it also significantly reduced the hepatic lipid peroxide and H<SUB>2</SUB>O<SUB>2</SUB> production. Accordingly, these results indicate that both 0.05 and 0.1% pinitol supplementation may improve the lipid and antioxidant metabolism in HFHC diet-fed hamsters. In particular, pinitol supplementation was very effective on the elevation of antiatherogenic factors, including plasma HDL-cholesterol, apo A-I, adiponectin, and PON.</P>
Purification and Characterization of Protein Phosphatase 2C from Rat Liver
Choi, Myung Un,Hwang, In Seong,Oh, Joung Sook 생화학분자생물학회 2000 BMB Reports Vol.30 No.3
Protein phosphatase 2C (PP2C) is one of the four major serine/threonine phosphatases which is dependent on Mg^(2+) for its activity. PP2C was purified from rat liver cytosol and its characteristics were investigated. The substrate employed for routine assay was [32P]casein phosphorylated by PKA. The purification process involved DEAE chromatography, ammonium sulfate fractionation, phenyl sepharose chromatography, sephacryl S-200 gel filtration, and histone agarose chromatography. The SDS-PAGE of PP2C showed one major single protein band at a position corresponding to a molecular mass of 43 kd and the purification fold was 637. The enzyme showed a pH optimum of 8 and KM value was 1.9 μM. However, when the substrate was changed to [^(32)P]histone, the pH optimum was shifted to 7 and K_M value was 2.3 μM. Mg^(2+) was essential to the enzyme activity and okadaic acid did not exert any inhibitory effect on the enzyme. To examine residue in the active site of PP2C, effects of some protein-modifying reagents were tested.
Generation of Pattern Classifiers Based on Linear Nongroup CA
Choi, Un-Sook,Cho, Sung-Jin,Kim, Han-Doo Korea Multimedia Society 2015 멀티미디어학회논문지 Vol.18 No.11
Nongroup Cellular Automata(CA) having two trees in the state transition diagram of a CA is suitable for pattern classifier which divides pattern set into two classes. Maji et al. [1] classified patterns by using multiple attractor cellular automata as a pattern classifier with dependency vector. In this paper we propose a method of generation of a pattern classifier using feature vector which is the extension of dependency vector. In addition, we propose methods for finding nonreachable states in the 0-tree of the state transition diagram of TPMACA corresponding to the given feature vector for the analysis of the state transition behavior of the generated pattern classifier.