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Phytochemical Characteristics of Coffee Bean Treated by Coating of Ginseng Extract
Sang Yoon Choi,Hee-Do Hong,Hye-Min Bae,Changsun Choi,Kyung-Tack Kim 고려인삼학회 2011 Journal of Ginseng Research Vol.35 No.4
The principal objective of this study was to assess the instrumental and sensory characteristics of ginseng coffee with different ratios of the ingredients: type of coffee bean (Colombia, Brazil, and Indonesia), type of ginseng extract (white ginseng, red ginseng, and America ginseng) and concentration of ginseng extract (3, 6, and 9 w/v %). The sensory optimal condition of white ginseng coffee, red ginseng coffee and America ginseng coffee were as follows: 3% Indonesian coffee bean coated with 3% white ginseng extract, Colombian coffee bean coated with 6% red ginseng extract and Colombian coffee bean coated with 3% American ginseng extract, respectively. In particular, the Colombian coffee bean coated with 6% red ginseng extract had significantly higher scores than other samples in terms of flavor, taste, and overall preference. Additionally, the contents of total ginsenoside and total sugar and total phenolic compounds were also highest in the Colombian coffee bean coated with 6% red ginseng extract.
Hepatitis E Virus Methyltransferase Inhibits Type I Interferon Induction by Targeting RIG-I
( Sangmin Kang ),( Changsun Choi ),( Insoo Choi ),( Kwi-nam Han ),( Seong Woon Roh ),( Jongsun Choi ),( Joseph Kwon ),( Mi-kyung Park ),( Seong-jun Kim ),( Jinjong Myoung ) 한국미생물생명공학회(구 한국산업미생물학회) 2018 Journal of microbiology and biotechnology Vol.28 No.9
The type I interferons (IFNs) play a vital role in activation of innate immunity in response to viral infection. Accordingly, viruses have evolved to employ various survival strategies to evade innate immune responses induced by type I IFNs. For example, hepatitis E virus (HEV) encoded papain-like cysteine protease (PCP) has been shown to inhibit IFN activation signaling by suppressing K63-linked de-ubiquitination of retinoic acid-inducible gene I (RIG-I) and TANK-binding kinase 1 (TBK1), thus effectively inhibiting down-stream activation of IFN signaling. In the present study, we demonstrated that HEV inhibits polyinosinic-polycytidylic acid (poly(I:C))-induced IFN-β transcriptional induction. Moreover, by using reporter assay with individual HEV-encoded gene, we showed that HEV methyltransferase (MeT), a nonstructural protein, significantly decreases RIG-I-induced IFN-β induction and NF-κB signaling activities in a dose-dependent manner. Taken together, we report here that MeT, along with PCP, is responsible for the inhibition of RIG-I-induced activation of type I IFNs, expanding the list of HEV-encoded antagonists of the host innate immunity.
박창선(Changsun Park),차용훈(Yonghoon Cha),성백섭(Backsub Sung),이석신(Seokshin Lee),배광석(Kwangsuk Bae),최귀현(Kuy syun Choi),김정주(JungjJoo Kim),김남표(Nampyo Kim),박성호(Sungho Park) 한국자동차공학회 2010 한국자동차공학회 부문종합 학술대회 Vol.2010 No.5
Die casting which is extensively known as a necessary technology for lightweight spare parts of automobiles has three central elements of casting equipment, casting technology and die and has had much attention as a technology with the highest coefficient of expansion with increased need of high-quality and high-precision. Therefore, a regulator of LPI automobile receives high internal pressure and works as a central part of the basic fuel supply system according to quality of performance. To produce high-quality casting goods, we need to identify causes of defects and theoretical analyses on physical phenomena occurring in manufacturing. As a result of comparing Types of casting design, it was found that the number of overflow affected flow, flow speed and solidification temperature.
안창선 ( Changsun Ahn ),박용호 ( Yongho Park ),문정대 ( Jungdae Moon ),박종찬 ( Jongchan Park ),서영곤 ( Youngkon Seo ),손유락 ( Allen Sohn ),최윤종 ( Yoonjong Choi ),하양화 ( Yanghwa Ha ),정봉수 ( Bongsu Jung ),김영주 ( Youngjoo 한국정보처리학회 2023 정보처리학회논문지. 컴퓨터 및 통신시스템 Vol.12 No.2
뎅기열 발병은 전 세계 인구의 약 1/3이 거주하고 있는 열대, 아열대 기후에 집중되며, 우리나라도 아열대 기후로 바꾸고 있어 뎅기열 발병에 취약해지고 있다. 뎅기열은 감염병 관리 차원에서 진단 이력 관리가 중요하다. 감염병 이력에 따라서 지역별, 연령별, 남녀비율 등에 따라서 개개인의 치료 방법과 전략을 수립할 수 있는 체계가 필요하다. 본 논문에서는 뎅기열 관제시스템을 제안하며, 이러한 시스템은 뎅기열의 발병에 대한 체외진단기기를 이용한 실시간 집계방식으로 발병률과 사망률을 감소시킬 수 있는 전략을 수립하는 데 유용하게 활용될 수 있다. 뎅기열 관리를 위한 관제시스템 구성으로 형광면역진단 키트를 이용한 뎅기열 체외진단기기와 실시간 뎅기열 관제시스템으로 구성되어 있다. 본 논문으로 개발된 뎅기열 관제시스템은 향후 정부의 감염병 통합정보와 결합되어 다양한 감염병 관리 및 정책 활용을 위해서 활용될 수 있을 것이다. Dengue virus transmission is a viral infection disease between humans and Aedes mosquitoes. Dengue is ubiquitous throughout the tropics and subtropical zones, where 1/3 of the global population live. The weather in Korea is also changing to subtropical weather, resulting in increased vulnerable Korean population to dengue virus transmission. It is important to control and prevent the dengue risk with track-recording & monitoring system. It is also required to have the control system to treat and monitor dengue patients with various cases such as regions, ages, genders according to the track-record of the disease. In this paper, we developed a Dengue Control & Prevention System, which can monitor and control dengue outbreaks in real-time with in-vitro diagnostic devices. Dengue Control & Prevention System is composed of in-vitro diagnostic device, which is a fluorescent immunoassay, and real-time monitoring system. In the future, we expect that our Dengue Control & Prevention System can be upgraded to have various disease information from Korea Disease Control and Prevention Agency for government policies and diseases control in Korea.