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      • KCI등재

        Potential of a combination of entomopathogenic fungal strains and a non-ionic surfactant to control the fall armyworm (Spodoptera frugiperda)

        Wu Sing-Shan,Tseng Ching-Tzu,Yang Yu-Hung,Liu Yao-Chia,Chang Ju-Chun,Gyawali Purushottam,Li Yi-Hsuan,Yang Tzu-Hao,Tsai Yi-Fang,Tang Li-Cheng,Nai Yu-Shin 한국응용곤충학회 2022 Journal of Asia-Pacific Entomology Vol.25 No.4

        The fall armyworm, Spodoptera frugiperda, is an emerging invasive pest in Taiwan that feeds on a wide range of crops and causes serious damage. Herein, an entomopathogenic fungal library (EFLib) was constructed to identify potential microbes to control FAW. Twenty-eight indigenous entomopathogenic fungi (EPF) were iso lated and investigated for their potential pathogenicity, with Metarhizium pinghaense (Mp-NCHU-124) and Beauveria bassiana (Bb-NCHU-157) exerting dose-dependent effects on the 4th instar FAW larvae. The non-ionic surfactant Silwet L-77 rapidly killed FAW larvae after spraying at a concentration of 300 mg/kg and the toxic effect of Silwet L-77 on FAW larvae was dose-dependent. When the EPF isolates (10 6 conidia/mL) were applied to FAW larvae in combination with the non-ionic surfactant Silwet L-77 (30–90 mg/kg), the mortality rate dramatically increased and the LT 50 reduced, with increased fungal mycosis (Mp-NCHU-124: 38% to 72% and Bb-NCHU-157: 20 to 62%), indicating the high compatibility of EPF with the non-ionic surfactant. Thus, the Silwet L-77+EPF combined formulation has potential for practical field application for FAW pest control and sustainable agriculture in the future.

      • KCI등재

        Double-Side Notched Long-Period Fiber Gratings fabricated by Using an Inductively Coupled Plasma for Force Sensing

        Yu-Lin Fang,Tzu-Hsuan Huang,Chia-Chin Chiang,Chao-Wei Wu 한국물리학회 2018 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.73 No.9

        This study used an inductively coupled plasma (ICP) dry etching process with a metal amplitude mask to fabricate a double-side notched long-period fiber grating (DNLPFG) for loading sensing. The DNLPFG exhibited increasing resonance attenuation loss for a particular wavelength when subjected to loading. When the DNLPFG was subjected to force loading, the transmission spectra were changed, showing a with wavelength shift and resonance attenuation loss. The experimental results showed that the resonant dip of the DNLPFG increased with increasing loading. The maximum resonant dip of the 40-m DNLPFG sensor was 26:522 dB under 0.049-N loading, and the largest force sensitivity was 436:664 dB/N. The results demonstrate that the proposed DNLPFG has potential for force sensing applications.

      • SCIESCOPUS

        Carbon Nanotube Array for Addressable Nano-Bioelectronic Transducers

        Jin Ho Kim,Withey, G,Chia-Hsuan Wu,Xu, J IEEE 2011 IEEE SENSORS JOURNAL Vol.11 No.5

        <P>Using densely packed and arrayed carbon nanotubes and by incorporating DNA as addressable linkers, we have succeeded in simultaneous, parallel binding of multiple different redox proteins to designated nanotube electrodes on an integrated chip. As a result, we have formed a nanoelectronic-protein transducer array which is capable of real-time, multiplexed detection of several analytes in parallel in one device. The sequence-specificity of DNA hybridization provides the means of encoding spatial address instruction to the self-assembling process and enables the desired programmability, scalability, and renewability. Our results demonstrate the feasibility of a new paradigm of biosensing: detection of not only the presence of the targeted substances but also the real-time activities of multiple biomolecules. In this system, the conjugated biomolecules and nanoelectronic components provide active monitoring and mediating functions in real time, and can be integrated en masse into large arrays in a silicon-based circuit.</P>

      • Design of a Bidirectional DC/AC Converter with Battery Charging/Discharging/Standing Balance Control

        Liang-Rui Chen,Bo-Rui Xu,Chuan-Sheng Liu,Shao-wei Peng,Chia-Hsuan Wu 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

        Battery cells connected in series have been widely used in high-voltage and high-power applications. In this paper, a single-phase battery energy storage system with battery balance charging, battery balance discharging, and power factor correction capabilities was developed. A prototype suitable for a single-phase 110V power supply was designed and implemented for verification. To verify its performance, three 48V/7Ah battery modules were used as normal batteries, and a 48V/5Ah battery module was used as a retired battery. The experimental results showed that the battery energy storage system has excellent battery balancing capability. Compared with that of the conventional system without balanced control, the balancing performance of the proposed system is increased by about 15.25% and 26.92%, respectively, when the system was operated in the converter and rectifier modes. In addition, the proposed system also had battery fault tolerance, and was compatible with recycled batteries and an independent power supply.

      • KCI등재

        A Systemic Review and Experts’ Consensus for Long-acting Injectable Antipsychotics in Bipolar Disorder

        Yuan-Hwa Chou,Po-Chung Chu,Szu-Wei Wu,Jen-Chin Lee,Yi-Hsuan Lee,I-Wen Sun,Chen-Lin Chang,Chien-Liang Huang,I-Chao Liu,Chia-Fen Tsai,Yung-Chieh Yen 대한정신약물학회 2015 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.13 No.2

        Bipolar disorder (BD) is a major psychiatric disorder that is easily misdiagnosed. Patient adherence to a treatment regimen is of utmost importance for successful outcomes in BD. Several trials of antipsychotics suggested that depot antipsychotics, including long-acting first- and second-generation agents, are effective in preventing non-adherence, partial adherence, and in reducing relapse in BD. Various long-acting injectable (LAI) antipsychotics are available, including fluphenazine decanoate, haloperidol decanoate, olanzapine pamoate, risperidone microspheres, paliperidone palmitate, and aripiprazole monohydrate. Due to the increasing number of BD patients receiving LAI antipsychotics, treatment guidelines have been developed. However, the clinical applicability of LAI antipsychotics remains a global cause for concern, particularly in Asian countries. Expert physicians from Taiwan participated in a consensus meeting, which was held to review key areas based on both current literature and clinical practice. The purpose of this meeting was to generate a practical and implementable set of recommendations for LAI antipsychotic use to treat BD; target patient groups, dosage, administration, and adverse effects were considered. Experts recommended using LAI antipsychotics in patients with schizophrenia, rapid cycling BD, BD I, and bipolar-type schizoaffective disorder. LAI antipsychotic use was recommended in BD patients with the following characteristics: multiple episodes and low adherence; seldom yet serious episodes; low adherence potential per a physician’s clinical judgment; preference for injectable agents over oral agents; and multiple oral agent users still experiencing residual symptoms.

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