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      • 악하선 암의 치료성적과 예후인자

        임치영(Chi Young Lim),남기현(Kee Hyun Nam),이잔디(Jan Dee Lee),장항석(Hang Seok Chang),정웅윤(Woong Youn Chung),차인호(In Ho Cha),이창걸(Chang Geol Lee),최은창(Eun Chan Choi),박정수(Cheong Soo Park) 대한두경부종양학회 2005 대한두경부 종양학회지 Vol.21 No.2

        Purpose: Submandibular gland tumor is rare, less than 6% of head and neck tumor. The purpose of this article is to analysis the clinical experience and treatment outcomes of malignant submandibular gland tumor, suggesting a guideline of management. Methods: We retrospectively evaluated 26 patients who underwent operation for malignant submandibular gland tumor at Severence hospital between 1986 and 2004. Statistical analysis was performed by Kaplan-Meier method, log rank test, Chi-square test, Fisher's exact test using SPSS v12.0 for Windows. Results: They consisted of 18 males and 8 females whose median age was 47 years(range: 20-71). 10 cases of adenocystic carcinoma, 8 cases of carcinoma ex pleomorphic adenoma, 4 cases of mucoepidermoid carcinoma, 1 case each for acinic cell carcinoma, undifferentiated carcinoma, adeno carcinoma, epithelioid hemangioendothelioma. Sialoadenectomy only was performed in 10 cases(36.5%) and sialoadenectomy with neck node dissection was performed in 16 cases(63.5%). Adjuvant radiotherapy was done in 22 cases(84.6%). 10 year disease free survival rate for malignant submandibular gland tumor was 63.1 % and 10 year overall survival rate for malignant submandibular gland tumor was 70.1%. In univariate analysis, prognostic factors affecting recurrence of malignant submandibular gland tumor was initially papable lateral neck node in physical examination and metastasis of lateral neck node in pathologic confirmation. The prognostic factors affecting survival of malignant submandibular gland tumor was tumor size, TNM stage, recurrence and type of recurrence. Conclusion: In this study, prognostic factors affecting recurrence of malignant submandibular gland tumor was initially papable lateral neck node in physical examination and metastasis of lateral neck node in pathologic confirmation. The prognostic factors affecting survival of malignant submandibular gland tumor was tumor size, TNM stage, recurrence and type of recurrence. To prevent recurrence and to improve survival, early diagnosis and aggressive surgery must be considered.

      • KCI등재

        구강악안면 영역에서 Tutoplast Dura의 임상적 적용

        지재휴,김영균,여환호,박인순,변웅래 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.1

        Human Dura mater treated by various processes was used to restore small periodontal defects, large bony defects for improvement of new bone formation, and soft tissue defects and replace the disc of TMJ, etc.. Tutoplast Dura is the solvent-preserved Human Dura mater and sterilized by gamma radiation. In our department, Tutoplast Dura was implanted in 32 patients, from 1994, 6 to 1995, 7. We implanted the Tutoplast Dura at 11 various cysts, 6 implantations, 4 fractures, 3 clefts, 2 TMJ disease, 2 maxillary sinusitis, etc.. We performed the retrospective study about the purpose of Tutoplast Dura implantation, postoperative complication and histologic examination of biopsy specimen at implant second surgery.

      • 계란으로 부터의 E. coli 특이 항체 대량 생산에 관한 연구

        인치웅,강창수,강병화 안성산업대학교 1995 論文集 Vol.27 No.-

        포르말린으로처리한 장독소 E. coli을 20주령닭(이사브라운)에 면역시켰을 때 약 2주 경과 후 계란에서 항 E. coli 특이 항체의 생성을 확인할 수 있었고, 8주 후에 최고치에 도달하였다. 그리고 난황의 특이 항체 역가는 25주 후까지 일정하게 유지되었다. 계란 항체 단백질은 PEG 분리·정제법으로 8.66㎎/㎖ 의 수율로 항체를 얻을 수 있으며, 이 항체의 역가는 파쇄된 E. coli을 이용한 ELISA로 측정하였다. 이 항체를 Trypticase Soy Brith에 1∼10㎎/㎖의 비율로 첨가하여 E. coli과 혼합 배양하였을 때 E. coli의 생장을 현저히 억제함을 알 수 있어 계란 항체를 이용한 설사 예방·치료제 및 건강 보조 식품 개발이 가능할 것으로 보인다. Hens immunized with formalin-treated E. coli antigen, and anti-E. coli antibody(IgG) could be detected in egg yolks 2 weeks after the first antigen injection, reached peak at about 8 seeks. Levels of specific antibody activity in egg yolk continued 25 weeks after first immunizqation. Active immunoglobulin protein was isolated from egg yolk of immunized chickens with PEG purification method. Purification yield was 8.66㎎ per 1㎖ egg yolk. The antibody activity was measured by using enzyme-linked immunosorbent assay (ELISA) with sonicated E. coli cell as antigen. The anti-E. coli antibody(IgG) inhibited E. coli growth in trypticase soy broth culture at low concentration(1∼10㎎ IgG/㎖ TSB). It appears possible to use IgG for the formulation of food and therapeutic products, especially diarrhea.

      • 말기신부전 환자에서 혈액투석 전후의 QT간격분산 비교

        강대웅,정지용,윤나라,안치용,김종오,신병철,정종훈,김현리 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

        Background: Some cases of QT interval, corrected QT interval (QTc), QT dispersion (QTd) and corrected QT dispersion (QTcd) have been reported in ESRD, but these results are variable and the influence of a hemodialysis is still controversial, In this study, we investigated the effect of hemodialysis on QT and QTc interval and QT and QTc dispersion in patients with ESRD 15 min before and 15 minute after each hemodialysis. Methods: Sixty-seven patients with ESRD (men 33 & women 34) on three-times stable hemodialysis (>3 months) were randomly enrolled. Fifty control subjects with a similar age and normal renal function were enrolled from this hospital. Routine biochemical studies were measured pre- and post dialysis, at the time of the ECG. Plasma Na+, K+, BUN, creatinine, ionized calcium and phosphate were checked. Twelve-lead electrocardiographs were performed at 10㎜/mv and 50㎜/s using a HewIett-Packard Pagewriter 100, before and after a single hemodialysis session.The QT interval was measured from the onset of the QRS complex to the end of the T wave. If the end of the T wave was not clear in a particular lead then it was excluded from analysis. When U waves were present, the end of the T wave was taken as the nadir between the T and U waves. Each QT interval was corrected for heart rate using Bazett's formula (QTc==QT/√(RR)) (ms). The difference between maximal and minimal QT interval duration was defined as QT dispersion (QTd) in each of the 12 leads. Result: This study demonstrates that QT, QTd, QTcd is higher in hemodialysis patients compared with control subjects, and QT and QTd rise postdialysis to levels comparable to those seen acutely following myocardial infarction, when patients are at greatly increased risk of potentially fatal ventricular arrhythmias, Conclusions: QT interval and QT dispersion, markers of risk for arrhythmias and sudden death, are elevated in hemodialysis patients, and rise postdialysis. QT interval and QT dispersion is an easily obtainable, noninvasive, simple, inexpensive, and widely available method of risk stratification in uremic patients receiving chronic dialysis. Additional studies are needed to clarity whether increased postdialysis QT dispersion results in an increased occurrence of arrhythmias.

      • 계사형태가 산란계의 생산성에 미치는 영향

        인치웅 안성산업대학교 1994 論文集 Vol.26 No.-

        무창계사와 개방계사가 산란계의 생산성에 미치는 영향을 조사하기 위하여 무창계사에는 Loman Brown종 산란계 70,000수를, 개방계사-I에는 Isa Brown종 산란계 13,530수를, 개방계사-Ⅱ에는 Manina Brown종 산란계 18,800수를 공시하여 1년간 생산성을 조사하였다. 산란율, 산란지수 및 성계의 생존율은 무참계사에서 개방계사보다 높았으며, 판란율은 무창계사에서 개방계사보다 낮았다. 사료요구율은 무창계사가 개방제사보다 낮았으며, 성성숙일령은 무창계사에서 개방계사에서 보다 늦었다. 난중은 무창계사에서의것이 개방계사보다 약간 높은 것으로 나타났다. To investigate the productivity of layer hens at windowless housing systems and window housing system, 70,000 birds of Loman Brown strain were housed in windoweless housing system and 13,530 birds of Isa Brown and 18,800 birds of Manina Brown were housed in tow window housing systems, repectively. Feeding trial was for 1 year and egg production, hen viability, egg weight and creaked eggs were collected. Hen-day egg production, hen-housed egg production, and hen's viability were higher in windowless housing system while cracked eggs were higher in window housing systems. Feed requirement was reduced in windowless housing system and sexual maturity earier in window housing systems than in windowless housing systems. The results indicate that the productivity of laying hen is higher in windowless housing system than in window housing system.

      • 물-LiBr吸收式 冷凍사이클의 性能豫測에 關한 硏究

        김문헌,권영필,신치웅 崇田大學校 1981 論文集 Vol.11 No.1

        The objective of this paper is to simulate the performance of H₂O-LiBr absorption refrigerator. The thermodynamic cycle of the H₂O-LiBr simple effect absorption refrigeration is analyzed and the coefficient of performance is derived for an ideal cycle. Equation for thermodynamic properties of LiBr solution and water are obtained by the least square method from equilibrium charts. And a computer program is developed, which can calculate the circulation ratic and the coefficient of performance from the efficiency of the heat exchanger and temperatures of generator, condenser, evaporator and absorber. The simulation of the performance by the computer shows the following characteristics. When the efficiency of the heat exhcnanger increase, the COP volue increases and the operating range is reduced by recry stallization. When the generator temperature increase, the COP value increases at a high condensor temperature but decrease at a low condenser temperature. However the COP value always increases as the condenser temperature decreases. It is more effective for high COP value to decrease the condenser temperature than to increase the generator temperature.

      • 좌측 광범위 경부 림프절 청소술 후 발생한 양측 유미흉 2예

        신종현(Jong-Hyun Shin),이잔디(Jandee Lee),윤지섭(Ji-Sup Yun),임치영(Chi-Young Lim),남기현(Kee-Hyun Nam),정웅윤(Woong Youn Chung),박정수(Cheong Soo Park) 대한두경부종양학회 2006 대한두경부 종양학회지 Vol.22 No.2

        Bilateral chylothorax as a complication of radical neck dissection is extremely rare. Early diagnosis of chy-lothorax is important due to the consequences on metabolic & cardiopulmonary conditions. This present report describes our recent experiences with two cases of bilateral chylothorax following left modified radical neck dissection that was treated successfully by conservative management.

      • KCI등재후보

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