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      • A facile drop-casting approach to nanostructured copper oxide-painted conductive woven textile as binder-free electrode for improved energy storage performance in redox-additive electrolyte

        Cha, S.,Nagaraju, G.,ChandraSekhar, S.,Yu, J. Royal Society of Chemistry 2017 Journal of Materials Chemistry A Vol.5 No.5

        <P>Hierarchical copper oxide (CuO) nanostructures (NSs) with caterpillar-like morphologies were facilely integrated onto a highly flexible conductive woven textile substrate (CWTs) by a drop-casting approach. Initially, the CuO NSs were synthesized via a simple and green wet-chemical method in 30 min and the obtained colloidal solution of CuO was easily dropped onto well-cleaned CWTs. By virtue of their interesting structural features, the caterpillar-like CuO NSs on CWTs were employed as binder-free electrodes for supercapacitors and their electrochemical properties were investigated in 1 M KOH solution. Additionally, a small portion of redox-additive potassium ferricyanide (K3Fe(CN)(6)) was added to the 1 M KOH solution, which led to efficient enhancement of energy storage performance with superior cycling stability for the caterpillar-like CuO NSs on CWTs. Furthermore, the fabricated asymmetric supercapacitor (SC) with CuO NSs on CWTs and activated carbon with an operating potential window of 1.5 V simultaneously exhibited excellent energy density and power density values. Such a simple and low-cost approach to easily construct metal oxide nanomaterials on flexible textiles with redox-additive electrolyte may be useful for several potential applications in high-performance energy storage devices.</P>

      • Differential proteome expression analysis of androgen-dependent and -independent pathways in LNCaP prostate cancer cells

        Cha, S.,Shin, D.H.,Seok, J.R.,Myung, J.K. Academic Press 2017 Experimental cell research Vol.359 No.1

        Prostate cancer (PC) is one of the leading causes of cancer death in men. It commonly develops in older males, but the number of younger men diagnosed with the disease has increased in recent years. Hormone therapies, such as chemical and surgical methods that inhibit androgen synthesis or androgen receptor (AR) activation, have been used for advanced disease. However, castration-resistant PC (CRPC), which exhibits androgen-independent mechanisms for activating AR, develops after a few years of such treatment and no therapy is available. In this study, we examined differences in the proteomes associated with the androgen-dependent (DHT treatment) and -independent (FSK, forskolin treatment) AR signaling conditions in LNCaP prostate cancer cells. Moreover, we used EPI-001, which inhibits AR-mediated transcriptional activity, to examine whether the observed differences in protein expression were directly affected by AR-mediated mechanisms. A total of 213 protein spots were matched in our 2-dimensional gel electrophoresis (2DE) analysis and 8 proteins with significant expression changes in our 5 different treatment groups were identified by mass spectrometry. Among these proteins, expression levels of PEPCK-M, catalase, tubulin alpha chain, alpha-enolase, and endoplasmic reticulum resident protein 29 were significantly altered by DHT and the levels of HSP 90 and EF-Tu were changed by FSK. These changes were blocked by EPI-001 in DHT-regulated proteins, PEPCK-M, catalase, and tubulin alpha chain and FSK-regulated EF-Tu protein. The results from our immunohistochemical analysis using in vivo xenograft models were consistent with the 2DE data. We therefore report the first identification of differences in proteins that are significantly regulated under androgen-dependent and -independent AR signaling conditions. Our findings could suggest a possible molecular mechanism through which AR is activated in the absence and/or presence of androgen, and might help explain the inhibitory action of EPI-001 on CRPC.

      • THE ANALYSIS OF SPARK PLUG VOLTAGE IN KNOCK DETECTING

        Xiaomin Wu,J.O,Chas,S.M.Lee,Y.S.Jung,J.K.Park,S.I.Moon 한국자동차공학회 1996 한국자동차공학회 춘 추계 학술대회 논문집 Vol.1996 No.11_2

        This paper describes a system for knock detection in automobile engine using the spark plug as a detecting probe. The authors carried out researches on a method which used ionic current of spark plug analysis for monitoring the combustion in an internal combustion engine. By this method, the spark plug was used as an ion density measurement probe directly, the flame behavior at the initial combustion stage was positively detected. The operations base on detection the ionic current which occurs when hydrocarbon is burned, by applying the DC bias voltage across the spark plug gap, thus the monitoring can be done in real time by processing Digital oscilloscope and the ionic current can be achieved.<br/> The results of experiment on four-cylinders engine could be included in this paper. By making use of the spark plug gap as an ion density measurement sensor, the authors analyze many factors for detecting ionic current (voltage), such as the polarity of bias voltage in a spark plug. the bias effect, the bias voltage, the ignition bum time and high voltage diode. The method can be effectively used for continuous monitoring of other factors in the internal combustion engine.<br/>

      • KCI등재후보

        China Central Television Headquarters-Structural Design

        Chris Carroll,Xiaonian Duan,Craig Gibbons,Richard Lawson,Alexis Lee,Andrew Luong,Rory Mcgowan,Chas Pope 한국강구조학회 2006 International Journal of Steel Structures Vol.6 No.5

        by a 9-storey podium structure joining two 50-storey high leaning towers which are linked at the top via a 13-storeycantilevered “overhang” structure at 36 storeys above the ground. This inovative and iconic shape of the building is exploitedto provide the primary structural support system, as well as achieving the architectural vision of high-rise ocupancy withintensity Beijing, is achieved by its external skin of leaning columns, horizontal beams and triangulated bracings forming anetwork of diagrids in an extremely strong closed braced tube structure. This external diagrid structure is also expressed boldlyin the building’s faade. It reinforces the transparency betwen structure and architecture, a central philosophy to the building’sbuilding height, in tune with the shape of the leaning towers. The columns emerge and terminate up the height of the building,again influenced by the angled towers. Transfer trusses are located at various levels to colect these column loads into the coresand external structure.

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