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      • KCI등재

        Anterior Cranial Base Reconstruction in Complex Craniomaxillofacial Trauma: An Algorithmic Approach and Single-Surgeon’s Experience

        Shakir Sameer,Card Elizabeth B.,Kimia Rotem,Greives Matthew R.,Nguyen Phuong D. 대한성형외과학회 2022 Archives of Plastic Surgery Vol.49 No.1

        Management of traumatic skull base fractures and associated complications pose a unique reconstructive challenge. The goals of skull base reconstruction include structural support for the brain and orbit, separation of the central nervous system from the aerodigestive tract, volume to decrease dead space, and restoration of the three-dimensional appearance of the face and cranium with bone and soft tissues. An open bicoronal approach is the most commonly used technique for craniofacial disassembly of the bifrontal region, with evacuation of intracranial hemorrhage and dural repair performed prior to reconstruction. Depending on the defect size and underlying patient and operative factors, reconstruction may involve bony reconstruction using autografts, allografts, or prosthetics in addition to soft tissue reconstruction using vascularized local or distant tissues. The vast majority of traumatic anterior cranial fossa (ACF) injuries resulting in smaller defects of the cranial base itself can be successfully reconstructed using local pedicled pericranial or galeal flaps. Compared with historical nonvascularized ACF reconstructive options, vascularized reconstruction using pericranial and/or galeal flaps has decreased the rate of cerebrospinal fluid (CSF) leak from 25 to 6.5%. We review the existing literature on this uncommon entity and present our case series of n = 6 patients undergoing traumatic reconstruction of the ACF at an urban Level 1 trauma center from 2016 to 2018. There were no postoperative CSF leaks, mucoceles, episodes of meningitis, or deaths during the study follow-up period. In conclusion, use of pericranial, galeal, and free flaps, as indicated, can provide reliable and durable reconstruction of a wide variety of injuries.

      • KCI등재

        Anterior Cranial Base Reconstruction in Complex Craniomaxillofacial Trauma: An Algorithmic Approach and Single-Surgeon’s Experience

        Shakir Sameer,Card Elizabeth B.,Kimia Rotem,Greives Matthew R.,Nguyen Phuong D. 대한성형외과학회 2022 Archives of Plastic Surgery Vol.49 No.2

        Management of traumatic skull base fractures and associated complications pose a unique reconstructive challenge. The goals of skull base reconstruction include structural support for the brain and orbit, separation of the central nervous system from the aerodigestive tract, volume to decrease dead space, and restoration of the three-dimensional appearance of the face and cranium with bone and soft tissues. An open bicoronal approach is the most commonly used technique for craniofacial disassembly of the bifrontal region, with evacuation of intracranial hemorrhage and dural repair performed prior to reconstruction. Depending on the defect size and underlying patient and operative factors, reconstruction may involve bony reconstruction using autografts, allografts, or prosthetics in addition to soft tissue reconstruction using vascularized local or distant tissues. The vast majority of traumatic anterior cranial fossa (ACF) injuries resulting in smaller defects of the cranial base itself can be successfully reconstructed using local pedicled pericranial or galeal flaps. Compared with historical nonvascularized ACF reconstructive options, vascularized reconstruction using pericranial and/or galeal flaps has decreased the rate of cerebrospinal fluid (CSF) leak from 25 to 6.5%. We review the existing literature on this uncommon entity and present our case series of n = 6 patients undergoing traumatic reconstruction of the ACF at an urban Level 1 trauma center from 2016 to 2018. There were no postoperative CSF leaks, mucoceles, episodes of meningitis, or deaths during the study follow-up period. In conclusion, use of pericranial, galeal, and free flaps, as indicated, can provide reliable and durable reconstruction of a wide variety of injuries.

      • KCI등재

        Light-emitting diode assessment of dentinal defects: the role of presumed extraction forces

        Coelho, Marcelo Santos,Card, Steven J.,Tawil, Peter Z. The Korean Academy of Conservative Dentistry 2017 Restorative Dentistry & Endodontics Vol.42 No.3

        Objectives: The evaluation of iatrogenic dentinal defects in extracted teeth may be influenced by extraction forces and prolonged dry times. The purpose of this study was to compare the presence of dentinal defects in freshly extracted, periodontally compromised teeth with those in a group of teeth with uncontrolled extraction forces and storage time. Materials and Methods: The experimental group consisted of eighteen roots obtained from teeth extracted due to periodontal reasons with class II or III mobility. They were kept in saline and sectioned within 1 hour following extraction. The control group consisted of matched root types obtained from an anonymous tooth collection, consistent with previous dentinal defect studies. The slices were obtained at 3, 6, and 9 mm from the apex. The imaging process exposed all specimens to no more than 60 seconds of dry time. The ${\times}12.8$ magnification was used for the 9 mm slices and ${\times}19.2$ magnification for the 3 mm and 6 mm slices under light-emitting diode (LED) transillumination. The root canal spaces and periodontal tissues were masked to minimize extraneous factors that might influence the evaluators. Chi-square test was used for statistical analysis. Results: Dentinal defects were detected in 17% of the experimental group teeth, compared to 61% of control teeth (p = 0.015). Conclusions: LED transillumination assessment of freshly extracted roots with class II or III mobility showed smaller number of dentinal defects than roots with uncontrolled storage time and extraction forces. The use of freshly extracted roots with mobility should be considered for future dental defect assessment studies.

      • KCI등재후보

        The Male Accessory Gland Substances of Lucilia illustris (I): Its Effect on Mating Receptivity

        이종진,이용민,Ring T. CARDE 한국곤충학회 2002 Entomological Research Vol.32 No.2

        In order to verify the physiological functions of male accessory gland (MAG) substances of the blow.y, Lucilia illustris Meigen, the growth and changes in metabolites of male accessory gland with aging, and the effect of male accessory gland extract on mating receptivity of L. illustris were examined. There was not a signi.cant difference in length of MAG with aging, but the width of MAG was grown widely from 0 to 5-days old apparently. Changes in glycogen, total protein and lipid of male accessory gland substances showed same patterns but total protein content was higher than the others. Therefore, male nutrition affected the production of male accessory proteins.During the mating fed unmated male transferred larger amount of protein than that of starved male. When male accessory gland homogenates injected, mating receptivity of gravid female was greatly inhibited comparing to control, suggesting that the accessory gland substances of L. illustris alters female mating receptivity after mating.

      • Technical Notes on Radio Navigation Services, Including MSI

        국승기,Michael D. Card 한국항해항만학회 2017 한국항해항만학회 학술대회논문집 Vol.2017 No.추계

        극동지역에서 Loran-C 국제협력 체인의 구성에 따란 한국, 중국, 러시아 3개국에 상호호혜원칙에 따라 이용범위의 증대 및 전파표지의 연구 발전을 도모하는 등 전파표지분야의 협력과 발전을 위하여 협정서에 명시된 정책수행과 협정 체약국간 활동을 조정하는 역할을 하며 초기( 92.9.7)에는 기관간의 협정으로 시작하였으나 00.12.22에 정부간 협정으로 변경되어 그동안 Loran-C 국제 협력체인을 구성하는 한편 전파표지에 관한 정보 교환 및 운영절차 마련 등으로 해상교통안전에 크게 기여하고 있다. 최근 해사안전정보(MSI) 제공과 GNSS 전파간섭에 대비한 위치정보 제공에 관한 관심이 대두되면서 향후 FENRS에서 협력하고 발전해나갈 방향을 제시하고자 한다.

      • 설치류에서 알파 Herpes 바이러스의 신경친화성과 침습

        김진상,이성준,Patrick, J. Card 대한물리치료학회 1997 대한물리치료학회지 Vol.9 No.1

        The ability of neurotropic alpha herpesviruses to replicate within synaptically linked neurons has made these pathogens valuable tools for transneuronal analysis. Recent studies suggest that unique gene products expressed by genetically engineered strains of virus may permit the use of multiple strains in complex tracing paradigms. In the present study we have examined the invasiveness of two genetically engineered strains of the swine pathogen known as pseudorabies virus(PRV). The two strains were isogenic with the attenuated Bartha strain of PRV; in one strain a lacZ reporter gene was inserted Into the gC locus (PRV-BaBlu; 4.75 × 10^(8) pfu/㎖) contrained a PRV envelope glycoprotein gene that was absent in PRV-BaBlu. Simultaneous or temporally separated sequential injection of 4㎕ of each strain into the ventral wall of the stomach produced a predictale course of retrograde synaptic infection. The results were as follows: 1. PRV-BaBlu and PRV-D infected the dorsal motor nucleus of vagus nerve(DMV) and paraventricular nucleus(PVN) 2. Invasion and replication of PRV-D occured at a faster rate than the parental strain or PRV-BaBlu. 3. PRV-D was much more virulent than PRV-BaBlu or the parental strain. 4. Co-injection of PRV-D and PRV-BaBlu produced an infection that was more virulent than that produced by the parental strain (PRV-Bartha). 5. Neurons in DMV were permissive to co-infection with PRV-D and PRV-BaBlu when they were injected simultaneously into the same site. 6. Replication of PPV-BaBlu was compromised by prior infection of the same circuit with PRV-D. 7. Prior infection of neurons with PRV-D maked them resistant to infection with PRV-BaBlu.

      • KCI등재

        Light-emitting diode assessment of dentinal defects: the role of presumed extraction forces

        Marcelo Santos Coelho,Steven J. Card,Peter Z. Tawil 대한치과보존학회 2017 Restorative Dentistry & Endodontics Vol.42 No.3

        Objectives: The evaluation of iatrogenic dentinal defects in extracted teeth may be influenced by extraction forces and prolonged dry times. The purpose of this study was to compare the presence of dentinal defects in freshly extracted, periodontally compromised teeth with those in a group of teeth with uncontrolled extraction forces and storage time. Materials and Methods: The experimental group consisted of eighteen roots obtained from teeth extracted due to periodontal reasons with class II or III mobility. They were kept in saline and sectioned within 1 hour following extraction. The control group consisted of matched root types obtained from an anonymous tooth collection, consistent with previous dentinal defect studies. The slices were obtained at 3, 6, and 9 mm from the apex. The imaging process exposed all specimens to no more than 60 seconds of dry time. The × 12.8 magnification was used for the 9 mm slices and × 19.2 magnification for the 3 mm and 6 mm slices under light-emitting diode (LED) transillumination. The root canal spaces and periodontal tissues were masked to minimize extraneous factors that might influence the evaluators. Chi-square test was used for statistical analysis. Results: Dentinal defects were detected in 17% of the experimental group teeth, compared to 61% of control teeth (p = 0.015). Conclusions: LED transillumination assessment of freshly extracted roots with class II or III mobility showed smaller number of dentinal defects than roots with uncontrolled storage time and extraction forces. The use of freshly extracted roots with mobility should be considered for future dental defect assessment studies.

      • SCOPUSKCI등재

        The Male Accessory Gland Substances of Lucilia illustris (I): Its Effect on Mating Receptivity

        Lee, Jong-Jin,Lee, Yong-Min,Carde, Ring-T. 한국곤충학회 2002 Entomological Research Vol.32 No.2

        In order to verify the physiological functions of male accessory gland (MAG) substances of the blowfly, Lucilia illustris Meigen, the growth and changes in metabolites of male accessory gland with aging, and the effect of male accessory gland extract on mating receptivity of L. illustris were examined. There was not a significant difference in length of MAG with aging, but the width of MAG was grown widely from 0 to 5-days old apparently. Changes in glycogen, total protein and lipid of male accessory gland substances showed same patterns but total protein content was higher than the others. Therefore, male nutrition affected the production of male accessory proteins. During the mating fed unmated male transferred larger amount of protein than that of starved male. When male accessory gland homogenates injected, mating receptivity of gravid female was greatly inhibited comparing to control, suggesting that the accessory gland substances of L. illustris alters female mating receptivity after mating.

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