http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Wild Carrot Oil Extract is Selectively Cytotoxic to Human Acute Myeloid Leukemia Cells
Tawil, Mirna,Bekdash, Amira,Mroueh, Mohammad,Daher, Costantine F.,Abi-Habib, Ralph J. Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2
Background: In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. Analysis of mechanism of cell death showed an increase in cells positive for annexinV and for active caspases, indicating that DCOE induces apoptotic cell death in AML. Inhibition of the MAPK pathway decreased sensitivity of AML cells to DCOE, indicating that cytotoxicity may be dependent on its activity. In conclusion, DCOE induces selective apoptosis in AML cells, possibly through a MAPK-dependent mechanism.
Al-Tawil, Karam,Casey, Joseph,Thayaparan, Prashant,Tavakkolizadeh, Adel,Sinha, Joydeep,Colegate-Stone, Toby Korean Shoulder and Elbow Society 2022 대한견주관절의학회지 Vol.25 No.2
Background: The prognostic factors for patients with full-thickness rotator cuff tears (RCTs) include tear size, muscle atrophy and fatty infiltration. However, the influence of early coexisting degenerative changes on RCT outcomes is unappreciated. The purpose of this study was to calculate the impact that pre-existing partial glenohumeral cartilaginous changes have on patients undergoing arthroscopic RCT repair. Methods: A study of 54 patients undergoing arthroscopic RCT repair was undertaken. The presence of co-existing patches of glenohumeral degenerative cartilaginous changes and RCT size was recorded at surgery. Pre- and postoperative outcomes were assessed using traditional (Oxford Shoulder Score [OSS], 5-level EuroQol-5D [EQ-5D-5L] questionnaire and EuroQol visual analog scale [EQ-VAS]) and patient-centric re-formatted prisms. Outcomes were assessed as an entire dataset, and sub-group analysis was performed according to the grade of co-existing arthritis and tear size. Results: Significant improvements (p<0.05) in clinical outcomes were recognized when assessed using either the traditional or reformatted prisms (average % improvements in OSS, EQ-5D-5L and EQ-VAS were 47%, 33% and 43%, respectively; average improvements in pain, function, and psychological well-being were 48%, 33% and, 29%, respectively). Positive gain was noted in all sub-groups of arthritic grading and tear size. Conclusions: Good clinical outcomes can be achieved following RCT repair even in the presence of local partial degenerative cartilage changes and advancing tear size. These benefits are patient-centered but require RCT repairability.
Hussein A.,El-Tawil M.,El-Tahan W.,Mahmoud, A. A. 국제구조공학회 2008 Structural Engineering and Mechanics, An Int'l Jou Vol.28 No.2
This paper considers the solution of the stochastic differential equations (SDEs) with random operator and/or random excitation using the spectral SFEM. The random system parameters (involved in the operator) and the random excitations are modeled as second order stochastic processes defined only by their means and covariance functions. All random fields dealt with in this paper are continuous and do not have known explicit forms dependent on the spatial dimension. This fact makes the usage of the finite element (FE) analysis be difficult. Relying on the spectral properties of the covariance function, the Karhunen-Loeve expansion is used to represent these processes to overcome this difficulty. Then, a spectral approximation for the stochastic response (solution) of the SDE is obtained based on the implementation of the concept of generalized inverse defined by the Neumann expansion. This leads to an explicit expression for the solution process as a multivariate polynomial functional of a set of uncorrelated random variables that enables us to compute the statistical moments of the solution vector. To check the validity of this method, two applications are introduced which are, randomly loaded simply supported reinforced concrete beam and reinforced concrete cantilever beam with random bending rigidity. Finally, a more general application, randomly loaded simply supported reinforced concrete beam with random bending rigidity, is presented to illustrate the method.
Proposal of Estimation Method for Non-linear Amplifier Characteristics in Satellite Channel
Boonsrimuang, Pisit,Naito, Katsuhiro,Mori, Kazuo,Paungma, Tawil,Kobayashi, Hideo 통신위성우주산업연구회 2005 Joint Conference on Satellite Communications Vol.2005 No.-
OFDM technique having the higher PAPR performance has been considered as unsuitable transmission technique for the non-linear satellite channel. To solve this problem, we have already proposed the OFDM-IDAR method, which can mitigate the non-linear distortion and achieve the higher transmission data rate with keeping the better BER performance. In the IDAR method, however the input and output relationships of non-linear amplifier characteristics located at the transmit earth station and satellite are required at the receiver. This paper proposes the estimation method for AM-AM and AM-PM conversions characteristics of non-linear amplifiers by using low PAPR preamble symbols. The various computer simulations are conducted in this paper to verify the effectiveness of proposed method in the non-linear satellite channel.
Kim, Dong-Joo,Naaman, Antoine E.,El-Tawil, Sherif Korea Concrete Institute 2009 International Journal of Concrete Structures and M Vol.3 No.2
This paper provides a brief summary of the performance of an innovative slip hardening twisted steel fiber in comparison with other fibers including straight steel smooth fiber, high strength steel hooked fiber, SPECTRA (high molecular weight polyethylene) fiber and PVA fiber. First the pull-out of a single fiber is compared under static loading conditions, and slip rate-sensitivity is evaluated. The unique large slip capacity of T-fiber during pullout is based on its untwisting fiber pullout mechanism, which leads to high equivalent bond strength and composites with high ductility. Due to this large slip capacity a smaller amount of T-fibers is needed to obtain strain hardening tensile behavior of fiber reinforced cementitious composites. Second, the performance of different composites using T-fibers and other fibers subjected to tensile and flexural loadings is described and compared. Third, strain rate effect on the behavior of composites reinforced with different types and amounts of fibers is presented to clarify the potential application of HPFRCC for seismic, impact and blast loadings.
Crack propagation speed in ultra high performance concrete (UHPC)
Pyo, S.,Alkaysi, M.,El-Tawil, S. Butterworth Scientific ; Elsevier Science Ltd 2016 Construction and Building Materials Vol.114 No.-
This paper investigates crack speed in ultra-high performance concrete (UHPC) using pre-notched three-point bending specimens. The experimental parameters are fiber volume fraction and rate of loading. A hydraulic servo-controlled testing machine is used to apply lower notch tip strain rates, in the range of 0.025-1.01/s, while a newly developed impact testing system is used to achieve higher notch tip strain rates, ranging from 6.8 to 41.11/s. A high-speed camera is used to record images of the UHPC specimens during testing. Notch tip strain and crack speed are computed from the images, which show that crack speed increases asymptotically as the crack initiation strain rate increases. Crack speeds of up to 514m/s were achieved at the lower notch tip strain rates and up to 1454m/s for the higher notch tip strain rates. The achieved relationships are incorporated into a recently proposed crack-velocity dependent dynamic fracture model. The model is validated using published experimental data and used to show that, like conventional concrete, the strain rate sensitivity of UHPC is strongly associated with the characteristics of dynamic crack growth.