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Byun, Hokyun,Jang, Jinhee,Choi, Hyun Seok,Jung, So-Lyung,Ahn, Kook-Jin,Kim, Bum-soo Korean Society of Magnetic Resonance in Medicine 2018 Investigative Magnetic Resonance Imaging Vol.22 No.3
Purpose: To assess associations between morphological characteristics of intracranial arteries in time-of-flight MR angiography (TOF-MRA) and atherosclerotic risk factors. Materials and Methods: From January 2014 to October 2015, a total of 129 patients (65 men and 64 women) without intracranial arterial stenosis > 50% were included in this study. All MRIs were performed using a 3T machine with 3D TOF-MRA sequences. We evaluated irregularity, tortuosity, and dilatation of intracranial arteries in maximal intensity projection (MIP) of TOF-MRA. Subjects' risk factors for atherosclerosis including history of hypertension and diabetes were collected by reviewing their medical records. Associations between morphological characteristics and each known atherosclerosis risk factor were examined using univariate regression analysis. Multivariate regression models were built to determine combined association between those risk factors and morphologic changes of intracranial arteries. Results: In multivariate analysis, hypertension (coefficient [95% CI]: 0.162 [0.036, 0.289], P = 0.012) and absence of diabetes (coefficient [95% CI]: -0.159 [-0.296, -0.023], P = 0.022) were associated with large diameter of intracranial arteries. Males (coefficient [95% CI]: 0.11 [-0.006, 0.23], P = 0.062) and higher age (coefficient [95% CI]: 0.003 [-0.001, 0.008], P = 0.138) had marginal association with increased diameter. Tortuosity was associated with old age (OR: 1.04 [1.02, 1.07], P < 0.001). Irregular contour of intracranial arteries was significantly associated with old age (OR: 1.05 [1.02, 1.09], P = 0.004), presence of diabetes (OR: 2.88 [1.36, 6.15], P = 0.0058), and previous ischemic stroke (OR: 3.91 [1.41, 11.16], P = 0.0092). Conclusion: Morphological characteristics (irregularity, tortuosity, dilatation) of intracranial arteries seen in TOF-MRA might be associated with atherosclerotic risk factors in subjects with no or mild stenosis.
김세권,최진삼,이창국,변희국,전유진,이응호,박인용 대전산업대학교 반도체기술연구소 1999 半導體技術硏究所報 Vol.1 No.-
참치 뼈에서 추출한 hydroxyapatite를 출발물질로 여러 가지 세라믹 복합체를 제조하여 인공체액에서의 hydroxyapatite 복합체간의 화학결합을 조사하였다. hydroxyapatite 복합체들은 인공체액에서 4주 후부터 화학 결합성질을 나타내었다. 결합강도는 bioglass가 가장 강하게 나타났으며, 조성에 따른 의존성은 관찰할 수 없었다. 인공체액에서 복합체들은 이들의 경계면에서 불균일 핵생성 및 성장에 의해 화학적 결합으로 이루어졌다. Chemical bonding was investigated in the simulated body fluid of several selected hydroxyapatite-containing composites. The hydroxyapatite-containing composites chemically bonded with each other in the simulated body fluid after 4 weeks. Bioglass was strongly bonded in the simulated body fluid, but bonding strength was not depended on composition. Their composite bodies were chemically bonded by heterogeneous nucleation and growth at the interfaces of the specimens in the simulated body fluid.
참치뼈로 부터 추출한 천연 Hydroxyapatite 의 특성
이창국(Chang Kook Lee),최진삼(Jin Sam Choi),전유진(You Jin Jeon),변희국(Hee Guk Byun),김세권(Se Kwon Kim) 한국수산과학회 1997 한국수산과학회지 Vol.30 No.4
For the effective utilization of the fish bone waste from seafood industry, the physical properties of the isolated hydroxyapatite from tuna bon have been investigated. On X-ray measurements, the chemical formula and phase of the bone calcined by various temperature were detected as Ca_(10)(PO₄)_6(OH)₂ and hydroxyapatite, respectively. It was shown that the chemical properties of apatite separated from tuna bone were controlled by Ca/P ratio. The mean agglomerate particle diameter was changed as a function of temperature. However, the particle shape has a geometrically non-regular types. These trends are consistent with SEM images. The composition of the bass-ceramic batch by calcined tuna bone was not perfectly agreed with the suggested data, but the partially substituted composition possibly shows the application of it as a bioceramic material.
방사선 조사에 의한 문어 자숙액의 항산화 활성 증가 원인 규명
최종일(Jong-il Choi),김연주(Yeon-Joo Kim),성낙윤(Nak-Yun Sung),김재훈(Jae-Hun Kim),안동현(Dong-Huyn Ahn),전병수(Byung-Soo Chun),조국연(Kook Yeon Cho),변명우(Myung-Woo Byun),이주운(Ju-Woon Lee) 한국식품영양과학회 2009 한국식품영양과학회지 Vol.38 No.1
문어 자숙액 에탄올 추출물의 감마선 및 전자선 조사에 의한 항산화능의 증가 원인을 규명하고자 본 실험을 실시하였다. 문어 자숙액 에탄올 추출물에 polyclar™를 처리하여 폴리페놀을 흡착시켜 제거한 자숙액 추출물의 방사선 조사에 따른 DPPH 라디칼 소거능 변화를 측정한 결과, 폴리페놀이 제거되지 않은 자숙액에서와 같은 방사선 조사에 의한 항산화능 증가가 확인되어졌다. 따라서 방사선 조사에 의한 자숙액의 항산화능의 증가는 폴리페놀에 의한 원인이 아닌것으로 판단되었다. 자숙액에 많은 함량을 차지하고 있는 단백질에 대한 방사선 영향을 확인하기 위하여 (NH4)2SO4를 이용한 침전법으로 분리하여 얻어진 문어 자숙액 단백질 수용액에 방사선 조사한 결과 감마선 및 전자선 조사에 의하여 50% 이상 라디칼 소거능이 증가하였다. 이러한 연구결과는 문어 자숙액에 감마선 및 전자선 조사를 적용하였을 때 항산화 활성이 증가하는 이유는 폴리페놀의 함량의 증가에 의한 것보다는 조사에 의해 단백질 구조가 변화되고 이에 따라 항산화 활성이 증가하게 되는 것이라고 사료된다. This study was conducted to investigate the reason for the increase in the antioxidant activity of cooking drip from Enteroctopus dofleini by gamma and electron-beam irradiation. To define the effect of irradiation on the antioxidant activity of polyphenol in cooking drip, polyphenol excluded cooking drip extracts were prepared with polyclar™. But, the antioxidant activity of the cooking drip extracts without polyphenol was still increased by both irradiations. Instead, the effect on the proteins in the cooking drips prepared by ammonium sulfate precipitation showed great increase in antioxidative activity by irradiation. From these results, it was concluded that the increase in the antioxidative activity in cooking drips by the irradiation was caused by the structural modification of proteins in the cooking drips.
Si 의 화학증착에 의한 MoSi2 확산층의 성장거동에 관한 연구
김재수,최종술,윤진국,변지영 대한금속재료학회(대한금속학회) 1995 대한금속·재료학회지 Vol.33 No.11
The growth behaviors of MoSi₂ diffusion layer formed by the reaction of the chemical vapor deposited Si with Mo substrate have been investigated in the temperature range between 850℃ and 1400℃ using coldwall horizontal reactor and SiCl₄-H₂system. The thickness of MoSi₂ diffusion layer was linearly increased with the square root of total gas flow rate of reactants and with the reactants ratio(SiCl₄/H₂) of 0.09 but constant over 0.09 due to etching process of Si by HCl at the deposition temperature of 1100℃. The growth of MoSi₂ diffusion layer on Mo substrate obeyed the parabolic rate law and rate constant was 2.26 ×10^(-5) ㎝ sec^(1/2) at 1100℃. The formation process of MoSi₂ diffusion layer was controlled by gas phase diffusion of reactants through a boundary layer to Mo substrate over 1000℃ and activation energy for the growth of it was 102 kJ/mole. But the rate determining step was solid diffusion of Si into it below 900℃ because activation energy for the growth of it was 223 kJ/mole, which was similar to that for diffusion of Si in MoSi₂