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Paraquat 투여 백서에서 Cyclophosphamide와 Dexamethasone의 치료 효과
신정철,신양수,유병전,임현성,정태흥,박찬국,오금탁,이병래 朝鮮大學校 附設 醫學硏究所 1991 The Medical Journal of Chosun University Vol.16 No.1
Paraquat (N,N'-dimethy 1-4,4'bipyrydinium : Gramoxone^(R), a widely used herbicide, is extremely toxic to all green plants and many eukaryotic organisms. In human, paraquat intoxication leads to multiple organ failure, it preferentially damages the lung, kidney and liver and may result in death. The participation of superoxide in initiating tissue damage by administration of paraquat is well known in which one electron reduction of paraquat leads to the formation of radical species which react with molecular oxygen to give superoxide. This process initiates immunological changes with the activation of neutrophilic leukocytes, which is related to further production of superoxide. In this experiment, therapeutic effects of cyclophosphamide and dexamethasone on blood cell count, malondialdehyde as a indicator of lipid peroxidation, and antioxidant enzymes levels in the lung, liver and kidney of paraquat intoxicated rats were inbestigated. The WBC count were significantly decreased by combined treatment of cyclophosphamide and dexamethasone in paraquat intoxicated rats at 3 and 5 days but RBC count were not changed. The contents of malondialdehyde were significantly decreased in the lung and Kidney by combined treatment at 10 days after paraquat intoxication. The catalase acitvities were markedly increased in the lung and liver of rats at 10 days after paraquat intoxication, and superoxide dismutase activities showed minimal changes in the lung, liver and kidney of rats by combined treatment. These results suggest that paraquat induced tissue damage in rats can be redeced by combined administration of cyclophosphamide and dexamethasone.
Jeon, Byoung-Gyu,Choi, Tae-Hoon,Do, Su-Min,Woo, Jae-Hyeon,Yoon, Tae-Hoon Institute of Electrical and Electronics Engineers 2018 IEEE transactions on electron devices Vol.65 No.10
<P>In this paper, we present the effects of curing temperature on switching between the transparent and translucent states in a polymer-stabilized liquid-crystal (PSLC) cell. When cured at a low temperature, polymer structures are formed without disturbing the initial alignment of LCs so that haze in the transparent state is dramatically reduced. Moreover, we can achieve very fast switching between the haze-free transparent and high-haze translucent states because there is a little degradation in the performance of the transparent and translucent states when the polymer concentration is increased. We demonstrated an ON–OFF response time of less than 3 ms and a gray-to-gray response time of less than 6 ms in a PSLC cell.</P>
Jeon, Jun Woo,Han, Jae Hee,Kim, Sung-Kon,Kim, Dong-Gyun,Kim, Yong Seok,Suh, Dong Hack,Hong, Young Taik,Kim, Tae-Ho,Kim, Byoung Gak The Royal Society of Chemistry 2018 Journal of materials chemistry. A, Materials for e Vol.6 No.19
<P>The growing demands of next-generation applications for high power and energy sources necessitate advances in hierarchically porous carbon-based energy storage materials, which improve the overall kinetics of electrolytic reactions by providing efficient ion and electron transport pathways and facilitate electrolyte infiltration into the electrode during charging/discharging. Herein, we fabricate hierarchically structured porous carbon electrodes (cNPIM), prepared by solution casting of a polymer of intrinsic microporosity (PIM-1) followed by nonsolvent-induced phase separation and carbonization. The obtained material exhibits a considerable surface area (∼2100 m<SUP>2</SUP>g<SUP>−1</SUP>), high electrical conductivity (150 S cm<SUP>−1</SUP>), high specific capacitances (345, 235, and 195 F g<SUP>−1</SUP>in three-, two-electrode aqueous systems, and two-electrode organic systems, respectively) at 1 A g<SUP>−1</SUP>, and an exceptional specific energy of 43.2 W h kg<SUP>−1</SUP>at a specific power of 1.25 kW kg<SUP>−1</SUP>, featuring a pore size gradient in the surface normal direction.</P>
Jeon, Bo-Young,Kim, Seung-Cheol,Je, Sungmo,Kwak, Jeongyeon,Cho, Jang-Eun,Woo, Jong-Tae,Seo, Sangkyo,Shim, Hang-Sub,Park, Byoung-Ok,Lee, Sung-Sik,Cho, Sang-Nae Elsevier 2010 Research in veterinary science Vol.88 No.3
<P><B>Abstract</B></P><P>An enzyme-linked immunosorbent assay (ELISA) using bulk tank milk samples was evaluated as a screening test for bovine tuberculosis (TB), a contagious chronic disease of cattle. An ELISA with MPB70, a major antigen of <I>Mycobacterium bovis</I> was performed using paired sets of milk and sera samples from 33 tuberculin-positive and 43 tuberculin-negative cattle. Anti-MPB70 antibodies were detected in milk samples and there was a significant correlation between seroreactivities of milk and sera samples (<I>R<SUP>2</SUP></I>=0.83). Using the tuberculin skin test as the reference test, the sensitivities of ELISA using milk and sera samples were 87.8% and 81.8%, respectively, and the specificities were 97.7% and 100%, respectively.</P><P>In the screening test using bulk tank milk samples from 931 dairy herds in Whasung, Gyeonggi-do, Korea, the positive rate for anti-MPB70 antibody was 4.5% (42/931) and the tuberculin-positive rate was 2.8% (26/931). Individual milk samples (<I>n</I>=253) were collected from randomly selected 8 problematic and 3 negative herds (positive and negative in the screening test by MPB70 ELISA using bulk tank milk samples, respectively) and tested by MPB70 milk ELISA. In the problematic herds, positive rates were 10.5% (20/190) for anti-MPB70 antibodies in milk ELISA and 2.1% (4/190) in the tuberculin skin test. More than one dairy cows were positive by milk ELISA among the problematic herds, and all tuberculin-positive dairy cows were positive in the milk ELISA. Further, no positive cows were detected in negative herds both by milk ELISA and tuberculin skin test. These results suggest that an ELISA, using bulk tank milk samples, might be a potential efficient screening test for bovine TB of dairy cows.</P>
저열량탄의 휘발분과 산소농도가 Tar와 Soot의 발생률에 미치는 영향
정태용(Tae Yong Jeong),김진호(Jin Ho Kim),이병화(Byoung Hwa Lee),송주헌(Ju Hun Song),전충환(Chung-Hwan Jeon) 한국연소학회 2012 KOSCOSYMPOSIUM논문집 Vol.- No.44
This study was performed to analyze coal flames and measure tar and soot yields and structures of chars for two coals depending on the volatile content by the LFR(Laminar Flow Reactor) which can be applied to a variety of coal researches. The results show that volatile contents and oxygen concentration have significant influence on length and width of the soot cloud and it also indicate that the length and width of the cloud in condition of combustion decrease than those of pyrolysis atmosphere. Until the sampling height reach at 50 mm, the tar and soot yields of Berau (Sub-bituminous) coal contained relatively lots of volatile matters are less than those of Glencore A.P. (Bituminous) coal. On the other hand, tar and soot yields of Berau coal are higher than those of Glencore A.P. coal by reacted residual volatile matter. In addition, the images of samples obtained from the particle separation system of the sampling probe support for above results with the yields, and the pore development of char surface by devolatilization.