Predicting Biodegradation and Safety of Chemical compounds by Microbial Catabolism

Bo Kyeng Hou(허보경),Kyo-Shik Park(박교식),Young-Do Jo(조영도),Ji Yoon Kim(김지윤),Kyu Suk Hwang(황규석) 한국가스학회 2005 한국가스학회 학술대회논문집 Vol.2005 No.5

An Adaptive Complementary Sliding-mode Control Strategy of Single-phase Voltage Source Inverters

Bo Hou,Junwei Liu,Fengbin Dong,Anle Mu 대한전기학회 2018 Journal of Electrical Engineering & Technology Vol.13 No.1

In order to achieve the high quality output voltage of single-phase voltage source inverters, in this paper an Adaptive Complementary Sliding Mode Control (ACSMC) is proposed. Firstly, the dynamics model of the single-phase inverter with lumped uncertainty including parameter variations and external disturbances is derived. Then, the conventional Sliding Mode Control (SMC) and Complementary Sliding Mode Control (CSMC) are introduced separately. However, when system parameters vary or external disturbance occurs, the controlling performance such as tracking error, response speed et al. always could not satisfy the requirements based on the SMC and CSMC methods. Consequently, an ACSMC is developed. The ACSMC is composed of a CSMC term, a compensating control term and a filter parameters estimator. The compensating control term is applied to compensate for the system uncertainties, the filter parameters estimator is used for on-line LC parameter estimation by the proposed adaptive law. The adaptive law is derived using the Lyapunov theorem to guarantee the closed-loop stability. In order to decrease the control system cost, an inductor current estimator is developed. Finally, the effectiveness of the proposed controller is validated through Matlab/Simulink and experiments on a prototype single-phase inverter test bed with a TMS320LF28335 DSP. The simulation and experimental results show that compared to the conventional SMC and CSMC, the proposed ACSMC control strategy achieves more excellent performance such as fast transient response, small steady-state error, and low total harmonic distortion no matter under load step change, nonlinear load with inductor parameter variation or external disturbance.

An Adaptive Complementary Sliding-mode Control Strategy of Single-phase Voltage Source Inverters

Hou, Bo,Liu, Junwei,Dong, Fengbin,Mu, Anle The Korean Institute of Electrical Engineers 2018 Journal of Electrical Engineering & Technology Vol.13 No.1

In order to achieve the high quality output voltage of single-phase voltage source inverters, in this paper an Adaptive Complementary Sliding Mode Control (ACSMC) is proposed. Firstly, the dynamics model of the single-phase inverter with lumped uncertainty including parameter variations and external disturbances is derived. Then, the conventional Sliding Mode Control (SMC) and Complementary Sliding Mode Control (CSMC) are introduced separately. However, when system parameters vary or external disturbance occurs, the controlling performance such as tracking error, response speed et al. always could not satisfy the requirements based on the SMC and CSMC methods. Consequently, an ACSMC is developed. The ACSMC is composed of a CSMC term, a compensating control term and a filter parameters estimator. The compensating control term is applied to compensate for the system uncertainties, the filter parameters estimator is used for on-line LC parameter estimation by the proposed adaptive law. The adaptive law is derived using the Lyapunov theorem to guarantee the closed-loop stability. In order to decrease the control system cost, an inductor current estimator is developed. Finally, the effectiveness of the proposed controller is validated through Matlab/Simulink and experiments on a prototype single-phase inverter test bed with a TMS320LF28335 DSP. The simulation and experimental results show that compared to the conventional SMC and CSMC, the proposed ACSMC control strategy achieves more excellent performance such as fast transient response, small steady-state error, and low total harmonic distortion no matter under load step change, nonlinear load with inductor parameter variation or external disturbance.

In Vitro and in Vivo Antitumor Evaluation of Berbamine for Lung Cancer Treatment

Hou, Zhi-Bo,Lu, Kai-Jin,Wu, Xiao-Li,Chen, Cong,Huang, Xin-En,Yin, Hai-Tao Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.4

Purpose: Lung cancer, one of the most frequently diagnosed cancers in the world, is characterized by relatively high morbidity and mortality. Berbamine (BER) has been initially reported to exert anti-proliferative effects against a series of cancers. Methods: In this study the in vitro cytotoxicity of BER was measured by MTT assay. In vivo anti-cancer efficacy of BER was assessed in A549 xenografts. Results: Cytotoxicity tests showed dose-dependent cell growth inhibition effects of BER against A549 cells. Moreover, BER significantly reduced the growth of lung cancer in a dose-dependent manner in nude mice with prolonged survival time. Conclusion: Therefore, BER might be in herbal medicine for cancer therapy and further efforts are needed to explore therapeutic strategies.

WebChemDB: An Integrated Chemical Database Retrieval System

Hou, Bo-Kyeng,Moon, Eun-Joung,Moon, Sung-Chul,Kim, Hae-Jin Korea Genome Organization 2009 Genomics & informatics Vol.7 No.4

WebChemDB is an integrated chemical database retrieval system that provides access to over 8 million publicly available chemical structures, including related information on their biological activities and direct links to other public chemical resources, such as PubChem, ChEBI, and DrugBank. The data are publicly available over the web, using two-dimensional (2D) and three-dimensional (3D) structure retrieval systems with various filters and molecular descriptors. The web services API also provides researchers with functionalities to programmatically manipulate, search, and analyze the data.

GENERALIZED MCKAY QUIVERS, ROOT SYSTEM AND KAC-MOODY ALGEBRAS

Bo Hou,Shilin Yang 대한수학회 2015 대한수학회지 Vol.52 No.2

Let Q be a finite quiver and G ⊆ Aut(kQ) a finite abelian group. Assume that Q^ and T are the generalized Mckay quiver and the valued graph corresponding to (Q,G) respectively. In this paper we dis- cuss the relationship between indecomposable Q^ -representations and the root system of Kac-Moody algebra g(T). Moreover, we may lift G to G ⊆ Aut(g(Q^)) such that g(T) embeds into the fixed point algebra g(Q^)G and g(Q^)G as a g(T)-module is integrable.

GENERALIZED MCKAY QUIVERS, ROOT SYSTEM AND KAC-MOODY ALGEBRAS

Hou, Bo,Yang, Shilin Korean Mathematical Society 2015 대한수학회지 Vol.52 No.2

Let Q be a finite quiver and $G{\subseteq}Aut(\mathbb{k}Q)$ a finite abelian group. Assume that $\hat{Q}$ and ${\Gamma}$ are the generalized Mckay quiver and the valued graph corresponding to (Q, G) respectively. In this paper we discuss the relationship between indecomposable $\hat{Q}$-representations and the root system of Kac-Moody algebra $g({\Gamma})$. Moreover, we may lift G to $\bar{G}{\subseteq}Aut(g(\hat{Q}))$ such that $g({\Gamma})$ embeds into the fixed point algebra $g(\hat{Q})^{\bar{G}}$ and $g(\hat{Q})^{\bar{G}}$ as a $g({\Gamma})$-module is integrable.

Investigation on the structural, electronic, elastic and mechanical properties of Ti2Al(C1-xOx) solid solutions: First-principles calculations

Hou Bo,Liu Pei,Wang Aiqin,Xie Jingpei 한국물리학회 2022 Current Applied Physics Vol.39 No.-

In the present work, the structural, electronic, elastic and mechanical properties of Ti2AlC and Ti2Al(C1-xOx) solid solutions were investigated using first-principles calculations for varied O content incorporation (x = 0, 0.125, 0.25, 0.375, 0.5). According to the calculation results, all Ti2Al(C1-xOx) solid solutions with various x values are stable, and the bonding strength of the Ti–Al bond increases with the doping of O element. In addition, the shear modulus G and C44 elastic constant of Ti2Al(C1-xOx) solid solutions are both lower than the bulk modulus B, indicating that the phase has good damage tolerance. Not only that, compared with Ti2AlC, the plasticity and toughness of Ti2Al(C1-xOx) solid solutions are improved with the increase of O atom doping and doping ratio. Simultaneously, the doping of O atom is also beneficial to reduce the generalized stacking fault energy of Ti2AlC, making the Ti2Al(C1-xOx) solid solutions more prone to shear deformation, thereby further enhancing plasticity.

Red green blue emissive lead sulfide quantum dots: heterogeneous synthesis and applications

Hou, Bo,Cho, Yuljae,Kim, Byung-Sung,Ahn, Docheon,Lee, Sanghyo,Park, Jong Bae,Lee, Young-Woo,Hong, John,Im, Hyunsik,Morris, Stephen M.,Sohn, Jung Inn,Cha, SeungNam,Kim, Jong Min Royal Society of Chemistry 2017 Journal of Materials Chemistry C Vol.5 No.15

<P>Visible emission colloidal quantum dots (QDs) have shown promise in optical and optoelectronic applications. These QDs are typically composed of relatively expensive elements in the form of indium, cadmium, and gallium since alternative candidate materials exhibiting similar properties are yet to be realized. Herein, for the first time, we report red green blue (RGB) photoluminescences with quantum yields of 18% from earth-abundant lead sulfide (PbS) QDs. The visible emissive property is mainly attributed to a high degree of crystallinity even for the extremely small QD sizes (1-3 nm), which is realized by employing a heterogeneous reaction methodology at high growth temperatures (>170 °C). We demonstrate that the proposed heterogeneous synthetic method can be extended to the synthesis of other metal chalcogenide QDs, such as zinc sulfide and zinc selenide, which are promising for future industrial applications. More importantly, benefiting from the enlarged band gaps, the as-prepared PbS solar cells show an impressive open circuit voltage (∼0.8 V) beyond that reported to date.</P>

Chemically encoded self-organized quantum chain supracrystals with exceptional charge and ion transport properties

Hou, Bo,Sohn, Myungbeom,Lee, Young-Woo,Zhang, Jingchao,Sohn, Jung Inn,Kim, Hansu,Cha, SeungNam,Kim, Jong Min unknown 2019 Nano energy Vol.62 No.-

<P><B>Abstract</B></P> <P>Artificially grown superstructures from small building blocks is an intriguing subject in ‘bottom-up’ molecular science and nanotechnology. Although discrete nanoparticles with different morphologies and physicochemical properties are readily produced, assembly them into higher-order structure amenable to practical applications is still a considerable challenge. This report introduces a stepwise heterogeneous approach for coupling colloidal quantum dots (QDs) synthesis with self-organization to directly generate quantum chains (QCs). By using vulcanized sulfur precursors, QDs are interdigitated into microscale chainlike supracrystals associated with oleylamine and oleic acid as structure directing agents. The cooperative nature of the QD growth and assembly have been extended to fabricate binary (PbS) and ternary metal chalcogenides (CuInS<SUB>2</SUB>) QC superstructures over a range of length scales. In addition, enhanced ion and charge transfer performance have been demonstrated which are determined to originate from the minimum interparticle distance and nearly bare nanocrystal surface. The process reported here is general and can be readily extended to the production of many other metal chalcogenide QD superstructures for energy storage applications.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A new methodology for chemical synthesis self-organized quantum chain supracrystals. </LI> <LI> Binary and ternary metal chalcogenides quantum chain superstructures have been demonstrated over a range of length scales. </LI> <LI> Enhanced electrochemical capacity and durability via preserved nanograin boundaries and long-range ordered configuration. </LI> <LI> Demonstrate exceptional charge and ion transport properties in DFT simulations and lithium-ion batteries. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>