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        Effect of surface treatments on shear bond strength of resin composite bonded to CAD/CAM resin-ceramic hybrid materials

        Gungor, Merve Bankoglu,Nemli, Secil Karakoca,Bal, Bilge Turhan,Unver, Senem,Dogan, Aylin The Korean Academy of Prosthodonitics 2016 The Journal of Advanced Prosthodontics Vol.8 No.4

        PURPOSE. The purpose of this study was to assess the effect of surface treatments on shear bond strength of resin composite bonded to thermocycled and non-thermocycled CAD/CAM resin-ceramic hybrid materials. MATERIALS AND METHODS. 120 specimens ($10{\times}10{\times}2mm$) from each material were divided into 12 groups according to different surface treatments in combination with thermal aging procedures. Surface treatment methods were airborne-particle abrasion (abraded with 50 micron alumina particles), dry grinding (grinded with $125{\mu}m$ grain size bur), and hydrofluoric acid (9%) and silane application. According to the thermocycling procedure, the groups were assigned as non-thermocycled, thermocycled after packing composites, and thermocycled before packing composites. The average surface roughness of the non-thermocycled specimens were measured after surface treatments. After packing composites and thermocycling procedures, shear bond strength (SBS) of the specimens were tested. The results of surface roughness were statistically analyzed by 2-way Analysis of Variance (ANOVA), and SBS results were statistically analyzed by 3-way ANOVA. RESULTS. Surface roughness of GC were significantly lower than that of LU and VE (P<.05). The highest surface roughness was observed for dry grinding group, followed by airborne particle abraded group (P<.05). Comparing the materials within the same surface treatment method revealed that untreated surfaces generally showed lower SBS values. The values of untreated LU specimens showed significantly different SBS values compared to those of other surface treatment groups (P<.05). CONCLUSION. SBS was affected by surface treatments. Thermocycling did not have any effect on the SBS of the materials except acid and silane applied GC specimens, which were subjected to thermocycling before packing of the composite resin.

      • KCI등재

        Evaluation of Cholinesterase Inhibitory and Antioxidant Activities of Wild and Cultivated Samples of Sage (Salvia fruticosa) by Activity-Guided Fractionation

        Fatma Sezer Şenol,Ilkay Erdogan Orhan,Sinem Aslan Erdem,Murat Kartal,Bilge Şener,Yu¨ksel Kan,Ferhat Celep,Ahmet Kahraman,Musa Dogan 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.11

        In European folk medicine, Salvia species have traditionally been used to enhance memory. In our previous study of 55 Salvia taxa, we explored significant anticholinesterase activity of cultivated S. fruticosa. In this study, we compared the inhibitory activity of dichloromethane, ethyl acetate, and ethanol extracts of 3 wild-grown samples and 1 cultivated sample of S. fruticosa against acetylcholinesterase and butyrylcholinesterase enzymes (which are associated with pathogenesis of Alzheimer's disease) by using the spectrophotometric Ellman method. Antioxidant activities were assessed by determining 2,2-diphenyl-1-picrylhydrazyl radical–scavenging activity, iron-chelating capacity, and ferric-reducing antioxidant power. The dichloromethane extract of the cultivated sample was then subjected to fractionation by using open column chromatography and medium-pressure liquid chromatography to obtain the most active fraction by activity-guided fractionation. All fractions and subfractions were tested in the same manner, and inactive subfractions were discarded. The essential oil of the cultivated sample was analyzed by gas chromatography–mass spectrometry.

      • SCOPUSKCI등재

        Disulfiram Implantation for the Treatment of Alcoholism: Clinical Experiences from the Plastic Surgeon's Point of View

        Sezgin, Billur,Sibar, Serhat,Bulam, Hakan,Findikcioglu, Kemal,Tuncer, Serhan,Dogan, Bilge Korean Society of Plastic and Reconstructive Surge 2014 Archives of Plastic Surgery Vol.41 No.5

        Background Disulfiram implantation is a widely used treatment alternative for alcohol abuse, yet reports on the surgical aspect of disulfiram implantation with respect to patient and drug-related treatment efficacy and wound complications are very limited. We present our clinical experiences with disulfiram implantation and discuss the surgical outcomes obtained with different anatomical planes for implantation. Methods Medical records of all patients referred to our clinic from the psychiatry department between 2007 and 2013 for disulfiram implantation were retrospectively analyzed. Implantation was carried out using 10 sterile Disulfiram tablets (WZF Polfa S.A.), each tablet containing 100 mg of disulfiram. The procedure was carried out by implanting the tablets randomly in either a subcutaneous or an intramuscular plane. The location and the plane of implantation and the complications were recorded for each patient and compared to determine the differences in the outcomes. Results A total of 32 implantation procedures were evaluated for this study. Twenty-five implants were placed in the intramuscular plane (78.2%), while seven implants were placed subcutaneously (21.8%). Exposure was encountered in three of the seven subcutaneous implants (42.9%), while no exposure was seen with the intramuscular implants. Incomplete absorption of the tablets was encountered in one patient with a previous subcutaneous implant who presented 1 year later for re-implantation as part of the continuation of therapy. Conclusions To overcome the issue of treatment continuation in the case of disulfiram therapy, which may be ceased due to frequently encountered wound complications, we believe that implantation in the subscapular intramuscular plane allows both uneventful healing and an out-of-reach implant location.

      • KCI등재

        Disulfiram Implantation for the Treatment of Alcoholism: Clinical Experiences from the Plastic Surgeon’s Point of View

        Billur Sezgin,Serhat Sibar,Hakan Bulam,Kemal Findikcioglu,Serhan Tuncer,Bilge Dogan 대한성형외과학회 2014 Archives of Plastic Surgery Vol.41 No.5

        Background: Disulfiram implantation is a widely used treatment alternative for alcoholabuse, yet reports on the surgical aspect of disulfiram implantation with respect to patientand drug-related treatment efficacy and wound complications are very limited. We presentour clinical experiences with disulfiram implantation and discuss the surgical outcomesobtained with different anatomical planes for implantation. Methods: Medical records of all patients referred to our clinic from the psychiatry departmentbetween 2007 and 2013 for disulfiram implantation were retrospectively analyzed. Implantationwas carried out using 10 sterile Disulfiram tablets (WZF Polfa S.A.), each tablet containing100 mg of disulfiram. The procedure was carried out by implanting the tablets randomly ineither a subcutaneous or an intramuscular plane. The location and the plane of implantationand the complications were recorded for each patient and compared to determine thedifferences in the outcomes. Results: A total of 32 implantation procedures were evaluated for this study. Twenty-fiveimplants were placed in the intramuscular plane (78.2%), while seven implants were placedsubcutaneously (21.8%). Exposure was encountered in three of the seven subcutaneousimplants (42.9%), while no exposure was seen with the intramuscular implants. Incompleteabsorption of the tablets was encountered in one patient with a previous subcutaneousimplant who presented 1 year later for re-implantation as part of the continuation of therapy. Conclusions: To overcome the issue of treatment continuation in the case of disulfiramtherapy, which may be ceased due to frequently encountered wound complications, webelieve that implantation in the subscapular intramuscular plane allows both uneventfulhealing and an out-of-reach implant location.

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