http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
질병의 활동도 지표로써 머리카락 중 미량의 구리와 아연의 분석
정한성,최범석 慶熙大學校 材料科學技術硏究所 1997 材料科學技術硏究論集 Vol.10 No.-
The copper and zinc in scalp hair are determined by the ICP-AES and the relations between the trace elements concentrations with disease activity for the rheumatoid arthritis are investigated. The concentrations of the metals are varied depending upon the distance from the skin. The concentrations at the distal are higher than that of the proximal. Zinc concentration of the rheumatoid arthritis patients is higher than that of the osteroarthritis ones, and the confidence level that the group are different lies 95-99%. However, copper concentration for rheumatoid arthritis patients is lower and the two groups are different with a 50-80% confidence level.
한검욱 ( Han¸ Gum-wook ),유석형 ( Yoo¸ Suk-hyung ),한범석 ( Han¸ Beom-seok ),안종문 ( Ahan¸ Jong-moon ),이한승 ( Lee¸ Han-seung ),신성우 ( Shin¸ Sung-woo ) 한국구조물진단유지관리공학회 2000 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.4 No.2
Corrosion of reinforcement is a major problem affecting a large number of reinforced concrete structures, this paper presents the results of an experimental study on reinforced concrete beams to determine their residual flexural capacity after undergoing different corrosion degrees (corrosion length, corrosion location, corrosion rate) of reinforcing bars. Corrosion was induced in the laboratory by an accelerated corrosion technique using two sources of external power supply. The results show marked reductions in flexural strength due to reinforcement corrosion.
The effects of glass fiber reinforcement on the mechanical behavior of polyurethane foam
Han, Dae-Suk,Park, In-Beom,Kim, Myung-Hyun,Noh, Byeong-Jae,Kim, Wha-Soo,Lee, Jae-Myung 대한기계학회 2010 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.24 No.1
In this paper, the mechanical properties of polyurethane foam (PUF) reinforced with glass fiber (RPUF) and non-reinforced PUF were investigated and compared to evaluate their structural applicability and failure criteria. The effects of glass fiber reinforcement were analyzed by tensile, compression, and repetitive impact testing. In the compression test, the differences of compressive response were analyzed by specimen directions, and tensile tests were carried out to evaluate the strain rate sensitivity of two materials in the low strain rate regime ($\acute{\varepsilon}$<0.1/s). Structural impact tests were carried out using dry drop tests and custom-made equipment. The dimensions of the test PUF specimens were $340mm{\times}340mm{\times}270mm$. Reaction forces were measured at the bottom of the specimen using impact load sensors with the capacity to measure up to 100 ton. Deformation due to impact load was measured using a high-speed camera system. The time histories of the impact load versus displacement behavior during repetitive impact loading were analyzed. This study presents a comprehensive understanding of the effect of fiber reinforcement on the mechanical behavior of PUF.
( Beom Kyung Kim ),( Hyon Suk Kim ),( Jun Yong Park ),( Do Young Kim ),( Sang Hoon Ahn ),( Chae Yoon Chon ),( Young Nyun Park ),( Kwang Hyub Han ),( Seung Up Kim ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1
Background/Aims: Liver stiffness measurement (LSM) and FibroTest (FT) are the most frequently used non-invasive surrogates for liver biopsies. Enhanced Liver Fibrosis (ELF) test consists of three serum markers (hyaluronic acid, aminoterminal propeptide of procollagen type III, and tissue inhibitor of matrix metalloproteinases-1). There has been no direct comparison of diagnostic values for hepatic fibrosis among these in Asian chronic hepatitis B (CHB) patients. Methods: We prospectively enrolled 170 CHB patients who underwent liver biopsies along with LSM, FT, and ELF. Fibrosis stage was assessed according to Batts and Ludwig system. Results: To predict significant fibrosis (F≥2), advanced fibrosis (F≥3), and cirrhosis (F=4), areas under receiver operating characteristic curves (AUROCs) of ELF were 0.901, 0.860, and 0.862, while those were 0.937, 0.956, and 0.963 for LSM and 0.896, 0.921, and 0.881 for FT, respectively. To predict F≥2, there was no significant difference in AUROCs each other, whereas for predicting F≥3, LSM and FT showed the better AUROCs than ELF (both p<0.05), and for predicting F4, LSM did better than ELF (p<0.05). Optimized cutoffs of ELF to maximize sum of sensitivity and specificity were 8.5, 9.4, and 10.1 for F≥2, F≥3, and F=4, respectively. Using suggested cutoffs of ELF, LSM and FT to diagnose F1, F2, F3, and F4, 91, 117, and 110 patients were correctly classified consistent with histological results, respectively. Conclusions: ELF demonstrated considerable diagnostic performance for non-invasive fibrosis staging in Asian CHB patients, especially in predicting F≥2. However, LSM consistently provided better diagnostic values for predicting F≥3 and F4.
( Beom Kyung Kim ),( Seung Up Kim ),( Hyon Suk Kim ),( Jun Yong Park ),( Sang Hoon Ahn ),( Chae Yoon Chon ),( In Rae Cho ),( Dong Hoo Joh ),( Young Nyun Park ),( Kwang Hyub Han ),( Do Young Kim ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1
Background/Aims: Diagnostic values of FibroTest (FT) for hepatic fibrosis have rarely been assessed in Asian chronic hepatitis B (CHB) patients. We aimed to validate its diagnostic performances in comparison with liver stiffness (LS). Methods: From 2008 to 2010, 194 CHB patients who underwent liver biopsies along with FT and transient elastography were prospectively enrolled. Fibrosis stage was assessed according to the Batts and Ludwig system. Results: To predict significant fibrosis (F≥2), advanced fibrosis (F≥3), and cirrhosis (F=4), areas under receiver operating characteristic curves (AUROCs) of FT were 0.903, 0.907, and 0.866, comparable to those of LS (0.873, 0.897, and 0.910, respectively). Optimized cutoffs of FT to maximize sum of sensitivity and specificity were 0.32, 0.52, and 0.68 for F≥2, F≥ 3, and F=4, while those of LS were 8.8, 10.2, and 14.1 kPa, respectively. According to FT and LS cutoffs, 123 (63.4%) and 124 (63.9%) patients were correctly classified consistent with histological fibrosis (F1, F2, F3, and F4), respectively. Overall concordance between each fibrosis stage estimated by FT and LS was observed in 111 patients, where 88 were correctly classified with histological results. A combination formula adding LS to FT (LS+FT) showed similar AUROC levels (0.885, 0.905, and 0.915), while another multiplying LS by FT (LS×FT) showed the best AUROCs (0.941, 0.931, and 0.929 for F≥2, F≥3, and F4, respectively). Conclusions: FT provides good fibrosis prediction, with comparable outcomes to LS in Asian CHB patients. FT substantially reduces need for liver biopsy, especially when used in combination with LS.
( Beom Kyung Kim ),( Seung Up Kim ),( Hyon Suk Kim ),( Jun Yong Park ),( Sang Hoon Ahn ),( Chae Yoon Chon ),( In Rae Cho ),( Dong Hoo Joh ),( Young Nyun Park ),( Kwang Hyub Han ),( Do Young Kim ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-
Background/Aims: Diagnostic values of FibroTest (FT) for hepatic fibrosis have rarely been assessed in Asian chronic hepatitis B (CHB) patients. We aimed to validate its diagnostic performances in comparison with liver stiffness (LS). Methods: From 2008 to 2010, 194 CHB patients who underwent liver biopsies along with FT and transient elastography were prospectively enrolled. Fibrosis stage was assessed according to the Batts and Ludwig system. Results: To predict significant fibrosis (F≥2), advanced fibrosis (F≥3), and cirrhosis (F=4), areas under receiver operating characteristic curves (AUROCs) of FT were 0.903, 0.907, and 0.866, comparable to those of LS (0.873, 0.897, and 0.910, respectively). Optimized cutoffs of FT to maximize sum of sensitivity and specificity were 0.32, 0.52, and 0.68 for F≥2, F≥3, and F=4, while those of LS were 8.8, 10.2, and 14.1 kPa, respectively. According to FT and LS cutoffs, 123 (63.4%) and 124 (63.9%) patients were correctly classified consistent with histological fibrosis (F1, F2, F3, and F4), respectively. Overall concordance between each fibrosis stage estimated by FT and LS was observed in 111 patients, where 88 were correctly classified with histological results. A combination formula adding LS to FT (LS+FT) showed similar AUROC levels (0.885, 0.905, and 0.915), while another multiplying LS by FT (LS×FT) showed the best AUROCs (0.941, 0.931, and 0.929 for F≥2, F≥3, and F4, respectively). Conclusions: FT provides good fibrosis prediction, with comparable outcomes to LS in Asian CHB patients. FT substantially reduces need for liver biopsy, especially when used in combination with LS.
Long-term clinical outcomes of peritoneal dialysis patients: single center experience from Korea.
Han, Seung Hyeok,Lee, Jung Eun,Kim, Dong Ki,Moon, Sung Jin,Kim, Hyun-Wook,Chang, Jae Hyun,Kim, Beom Seok,Kang, Shin-Wook,Choi, Kyu Hun,Lee, Ho Yung,Han, Dae Suk Pergamon Press ; Multimed Inc 2008 Peritoneal dialysis international Vol.28 No.suppl3
<P>Of a large body of literature reporting clinical outcomes for patients maintained on peritoneal dialysis (PD), most publications have focused on relatively short-term results. Few reports have focused on long-term survival in PD patients. Here, we present our experience with long-term patient outcomes and further analyses of the trends in demographics and clinical outcomes of 2301 end-stage renal disease (ESRD) patients treated with continuous ambulatory PD (CAPD) during a 25-year period (1981 - 2005) at our institute. Outcomes were analyzed for 1656 patients, excluding those younger than 15 years of age at initiation of CAPD, those having less than 3 months' follow-up, or those who had been on hemodialysis or who received a kidney graft before starting CAPD. In the study patients, technique survival at 5 and 10 years was 71.9% and 48.1% respectively. Patient survival was 69.8% and 51.8%. Mean age at the start of PD (50.4 +/- 13.9 years vs. 44.2 +/- 13.9 years, p < 0.01), ESRD incidence as a result of diabetic nephropathy (30.5% vs. 19.5%, p < 0.01), and incidence of cardiovascular comorbidities (26.6% vs. 20.5%, p < 0.01) were all significantly greater in patients who started PD during the second half of the study period (1993 - 2005) as compared with the first half (1981 - 1992). A multivariate analysis adjusting for these changes in demographics and comorbid conditions revealed that PD therapy starting in 1993 - 2005 was associated with a significant reduction in technique failure [hazard ratio (HR): 0.65; p < 0.01] and mortality (HR: 0.68; p < 0.01) as compared with the earlier period. However, in subgroup analyses, technique survival was not observed to be significantly improved in patients with diabetes. In summary, technique and patient survival have significantly improved despite increases in patient age, cardiovascular comorbidity, and ESRD caused by diabetes. Although diabetes, older age, and cardiovascular comorbidities are not factors that are easily modifiable to improve PD outcomes, results at our institution are encouraging in an era of declining PD utilization.</P>
Characteristics of Muscle Activity in the Lower Extremity during Stepping over Various Obstacle
( Han-suk Lee ),( Seung-beom Hong ),( Ha-nul Chin ),( Ju-li Choi ),( Hee-chang Seon ),( Duk-young Jeong ) 대한물리의학회 2019 대한물리의학회지 Vol.14 No.4
PURPOSE: This study examined the muscle activity while stepping over obstacles with various heights and widths to provide basic data for training and preventing falls. METHODS: Fifteen normal young adults (seven males and eight females) were recruited. The participants walked on a 5m walkway with six obstacles. The heights of obstacles were 0%, 10%, and 40% of the subject's leg length, and the width of the obstacles was 7cm and 14cm. The participants traversed the course twice per obstacle. The muscle activities of the soleus, tibialis anterior (TA), vastus medialis (VM), and vastus lateralis (VL) were measured using surface electromyography. A Mann-Whitney test and Kruskal- Wallis test were used to examine the differences between obstacles. RESULTS: The muscle activities of the VL and the soleus of the stance leg and lead leg after crossing over the obstacles increased with increasing width, and there were significant differences in muscle activities between obstacle width (p<.05) except for the muscle activity of TA of the stance leg after crossing over the obstacles. A significant difference in muscle activities was observed according to the height of the obstacles with 14 cm (p<.05) except for the muscle activity of the VL, soleus of the leading leg, and TA of the stance leg CONCLUSION: The role of the VL and Soleus increased with increasing obstacle width, and the overall muscle activities of the lower extremities increased with increasing obstacle height. These results can be used to suggest a program to prevent falls.