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        Crystallization behavior of tantalum and chlorine co-substituted hydroxyapatite nanopowders

        Bahman Nasiri-Tabrizi,Belinda Pingguan-Murphy,Wan Jefrey Basirun,Saeid Baradaran 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.33 No.-

        The crystallization behavior of tantalum and chlorine co-substituted hydroxyapatite nanopowders wasexamined. Results showed that combined processing by mechanical alloying and annealing is conduciveto the structural changes and crystal growth. A series of nanocrystalline tantalum and chlorine cosubstitutedhydroxyapatite (Ta/Cl–HA) with different dopant contents were synthesized as a result ofthe progressive mechanochemical reaction. During the subsequent annealing, crystallization of the asmilledpowders occurred, leading to a significant increase in the fraction of crystalline phase. TEMimages revealed that the crystallized and doped nanopowders composed of crystalline nanoneedles withan average size of 61 26 nm.

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        Advances in Smartphone-Based Point-of-Care Diagnostics

        Xiayu Xu,Akay, Altug,Huilin Wei,ShuQi Wang,Pingguan-Murphy, Belinda,Erlandsson, Bjorn-Erik,XiuJun Li,WonGu Lee,Jie Hu,Lin Wang,Feng Xu IEEE 2015 Proceedings of the Institute of Electrical and Ele Vol.103 No.2

        <P>Point-of-care (POC) diagnostics is playing an increasingly important role in public health, environmental monitoring, and food safety analysis. Smartphones, alone or in conjunction with add-on devices, have shown great capability of data collection, analysis, display, and transmission, making them popular in POC diagnostics. In this article, the state-of-the-art advances in smartphone-based POC diagnostic technologies and their applications in the past few years are outlined, ranging from in vivo tests that use smartphone's built-in/external sensors to detect biological signals to in vitro tests that involves complicated biochemical reactions. Novel techniques are illustrated by a number of attractive examples, followed by a brief discussion of the smartphone's role in telemedicine. The challenges and perspectives of smartphone-based POC diagnostics are also provided.</P>

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        Conversion of calcite from cockle shells to bioactive nanorod hydroxyapatite for biomedical applications

        Nur Ain Iftitah Mohamad Razali,Sumit Pramanik,Noor Azuan Abu Osman,Zamri Radzi,Belinda Pingguan-Murphy 한양대학교 세라믹연구소 2016 Journal of Ceramic Processing Research Vol.17 No.7

        Bioactive ceramics such as hydroxyapatite (HA) can mimic the organic structure of human bone. HA was successfullysynthesized from animal bones, corals, and eggshells which have been studied for bone repairing treatment and as implantcoatings. This study aims to synthesize nanorod HA from cockle shells via two routes: calcination and the hydrothermalmethod. The raw cockle shells were converted to calcite by calcination method at 450 oC (CS450) and 800 oC (CS800) for 2 hrs. The calcite calcium carbonate samples were reacted with diammonium hydrogen phosphate and hydrothermally treated at110 oC. The pH of the solution was kept at 10.5 throughout the synthesis step by adding drops of ammonia. Product obtainedwas labelled as HA450 and HA800 containing HA powder. Presence of calcite phase in the raw cockle shells was characterizedby utilizing Thermogravimetric analysis (TGA), X-ray Diffraction (XRD) and Fourier transforms infrared spectrophotometer(FTIR) analyses and morphologically analyzed by Field emission scanning electron microscopy (FESEM). The best result wasobtained from the HA800 sample where nanoparticle with rod-like shape was observed (aspect ratio = 7) while needle-likeparticle was seen in HA450 sample (aspect ratio = 20). High purity HA was developed in HA800 sample while HA450 showedsmall presence of calcite phase. In vitro bioactivity test of HA powder samples incubated simulated body fluid (SBF) for 1, 3,8, 15 and 21 days showed high bioactivity in both samples by forming apatite agglomerate on the surfaces. Highermicrohardness strength was observed in HA800 compared to HA450, CS450 and CS800 sintered pellet samples.

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