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소음 특수건강진단 1차검사의 민감도와 특이도에 미치는 일과성 역치 상승과 주변환경 소음의 영향
원종욱,방문규,송중호,정선아,송재석,노재훈 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2
Object : This study was performed to increase the sensitivity and specificity for screening the examinee of second hearing test. Methods : Study subjects were 219 workers who exposed more than average 80dB. They were taken the hearing test two times, before noose exposure and at 1 hour to 4 hours after worksite noise exposure. To investigate the ambient noise workers who were taken the hearing test in the test room which ambient noise was less than 45dB were classified Group I and the others were classified Group II . To calculate the sensitivity and specificity we made it gold standard whether worker had noise induced hearing loss. Results : Difference of hearing loss between before and after noise exposure for left and right ear was 11.4 dB and 11.7 dB respectively at 500 Hz, 8.7 dB and 9.6 dB at 1,000 Hz, 6.3 dB and 6.9 dB at 2,000 Hz and 6.9 dB and 7.4 dB at 4,000 Hz In Group I. That for left ear and right ear was 5.8 dB and 4.9 dB at 500 Hz respectively, 5.4 dB and 6.4 dB at 1,000 Hz, 6.3 dB and 5.3 dB at 2,000 Hz, and 5.5 dB and 5.8 dB at 4,000 Hz in Group II. The sensitivity was 100 in both Groups and the specificity was increased to 58.3 and 71.8 in Group I and Group II respectively until 10 dB was deducted from hearing level at 1,000 Hz and 4,000 Hz. Conclusion : When the screening hearing test was performed at worksite, we might deduct 10 dB from measured hearing level to increase the specificity without reduction of sensitivity.
Electron Cyclotron Resonance O_2 Plasma에서 증착한 규소 산화 박막의 특성
안명환,서문석,장재선,서성모,이기방,윤창주,이형재,남기석,최규현,손춘배,김용섭,강석희 全北大學校 基礎科學硏究所 1994 基礎科學 Vol.17 No.-
규소 산화막을 ECR-CVD(electron cyclotron resonance-chemical vapor deposition) 증착방법으로 5인치 기판위에 상온에서 증착하고, 증착공정조건인 증착율, 기판온도, 마이크로파의 세기변화 및 플라즈마 혼합기체의 비에 따른 규소 산화막의 특성을 조사하였다. 또한 산화막의 구조적인 특성을 비교하기 위해 FTIR을 이용하여 ECR-CVD 증착한 산화막, RPE-CVD(remote plasma enhanced-CVD) 증착한 산화막 및 열 산화막의 stretching frequency를 측정하였다. 측정된 결과 ECR-CVD로 증착된 산화막이 구조적인 면에서 열 산화막과 거의 같음을 보였다. ECR-CVD로 증착된 산화막의 전기적인 특성을 전류-전압 및 축전-전압 측정에의하여 분석하였다. 축전된 산화막의 전기적인 특성은 산화막의 전하 밀도는 1×10 exp (11)/㎠이였고, 평균 절연 파괴 전압은 약 6 MV/㎝이다. We have grown thin films of SiO_2 at room temperature by using an ECR-CVD system and have investigated the changes in the properties of the deposited films with changes in the processing conditions such as the deposition rate, the substrate temperature, the microwave power and the plasma gas mixing ratio. We also measured the stretching frequency of three kinds of oxides, and ECR-CVD-grown oxide, a PECVD-grown oxide, and a thermally grown oxide, using FTIR analysis to compare their structural properties. The result shows that the structural properties of the ECR-grown oxide are similar to those of the thermally grown oxide. Additionally, the electrical properties of the ECR-grown oxide were investigated by using current-voltage and capacitance-voltage measurements. These electrical results indicate that the oxide charge density and the average breakdown voltage are 1×10 exp (11) ㎝^-2 and 6 MV/㎝, respectively.
Preparation and Characterization of Amine-modified Gradient Polyethylene Surfaces
Kim, Moon Suk,Cho, Young Ho,Lee, Soo Young,Khang, Gilson,Lee, Tae Geol,Moon, Dae Won,Lee, Hai Bang The Chemical Society of Japan 2006 Chemistry letters Vol.35 No.7
<P>A gradient polyethylene (PE) surface was created through corona treatment, in which the corona power increased along the 5-cm length of the PE. The gradient PE surface was treated by amines with varying molecular weights. TOF–SIMS results exhibited the gradient surface images and intensities before and after amine modification on the corona-treated PE surface.</P>
Park, Ki-Suk,Jin Chae-Moon,Kim, Soon-Hee,Rhee John M.,Khang Gil-Son,Han, Chang-Whan,Yang, Yoon-Sun,Kim, Moon-Suk,Lee, Hai-Bang The Polymer Society of Korea 2005 Macromolecular Research Vol.13 No.4
We developed alginate beads loaded with transforming growth $factor-{\beta}_{1}(TGF-{\beta}_{1})$ to examine the possible application of the scaffold and cytokine carrier in tissue engineering. In this study, bone marrow stromal cells (BMSCs) and $TGF{\beta}_{1}$ were uniformly encapsulated in the alginate beads and then cultured in vitro. The cell morphology and shape of the alginate beads were observed using inverted microscope, scanning electron microscope (SEM), histological staining and RT-PCR to confirm chondrogenic differentiation. The amount of the $TGF{\beta}_{1}$ released from the $TGF-{\beta}_{1}$ loaded alginate beads was analyzed for 28 days in vitro in a phosphate buffered saline (pH 7.4) at $37^{\circ}C$. We observed the release profile of $TGF-{\beta}_{1}$ from $TGF-{\beta}_{1}$ loaded alginate beads with a sustained release pattern for 35 days. Microscopic observation showed the open cell pore structure and abundant cells with a round morphology in the alginate beads. In addition, histology and RT-PCR results revealed the evidence of chondrogenic differentiation in the beads. In conclusion, these results confirmed that $TGF-{\beta}_{1}$ loaded alginate beads provide excellent conditions for chondrogenic differentiation.
Molecular typing of Prototheca zopfii isolated from bovine mastitic milk samples in Korea
Ho Sung Park(Ho Sung Park),Su Jeong Kim(Su Jeong Kim),Geum-Chan Jang(Geum-Chan Jang),Bang-Hun Hyun(Bang-Hun Hyun),Suk-Kyung Lim(Suk-Kyung Lim),Dong Chan Moon(Dong Chan Moon) 한국예방수의학회 2017 한국예방수의학회 학술대회자료집 Vol.2017 No.-
Bang, S.-H.,Suk, Jae-Ho,Kim, Kun-Su,Park, Jong-Hwan,Hwang, Nong-Moon Elsevier 2019 THIN SOLID FILMS - Vol.669 No.-
<P><B>Abstract</B></P> <P>SiO<SUB>x</SUB>N<SUB>y</SUB> barrier films were deposited at low temperature of ~ 23 °C using inductively coupled plasma chemical vapor deposition (ICP-CVD). When radio frequency power increased at constant ratios of Ar/SiH<SUB>4</SUB> and O<SUB>2</SUB>/(O<SUB>2</SUB> + N<SUB>2</SUB>), respectively, of 4.5 and 0.1, the aggregation tendency of nanoparticles slightly decreased, whereas when the ratio of Ar/SiH<SUB>4</SUB> was changed from 4.5 to 41, almost spherical nanoparticles, each of which was isolated without aggregation, were observed. Such a near spherical nanoparticle without aggregation produced highly dense films with enhanced barrier property. However, heavily aggregated nanoparticles produced very porous films with deteriorated barrier property. In other words, the film density and barrier property depended significantly on whether nanoparticles were isolated or aggregated. To investigate the formation mechanism of dense SiO<SUB>x</SUB>N<SUB>y</SUB> barrier film, a transmission electron microscope grid membrane was exposed for 5 s to capture nanoparticles generated in the gas phase using a shutter above the grid membrane during ICP-CVD and the grid membrane was observed by scanning transmission electron microscope. The formation mechanism of the barrier film could be best explained by non-classical crystallization of CVD films, where nanoparticles formed in the gas phase contribute to the film formation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> SiO<SUB>x</SUB>N<SUB>y</SUB> barrier films were deposited by ICP-CVD. </LI> <LI> Effects of gas ratio and plasma power on the nanoparticle characteristics were studied. </LI> <LI> Gas ratio and plasma power greatly affect the film density and barrier property. </LI> <LI> The formation of dense film could be explained by non-classical crystallization of CVD. </LI> </UL> </P>