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        Stem Cell Tracing Through MR Molecular Imaging

        Rasoul Yahyapour,Bagher Farhood,Ghazale Graily,Abolhasan Rezaeyan,Saeed Rezapoor,Hamid Abdollahi,Mohsen Cheki,Peyman Amini,Hengameh Fallah,Masoud Najafi,Elahe Motevaseli 한국조직공학과 재생의학회 2018 조직공학과 재생의학 Vol.15 No.3

        Stem cell therapy opens a new window in medicine to overcome several diseases that remain incurable. It appears such diseases as cardiovascular disorders, brain injury, multiple sclerosis, urinary system diseases, cartilage lesions and diabetes are curable with stem cell transplantation. However, some questions related to stem cell therapy have remained unanswered. Stem cell imaging allows approval of appropriated strategies such as selection of the type and dose of stem cell, and also mode of cell delivery before being tested in clinical trials. MRI as a non-invasive imaging modality provides proper conditions for this aim. So far, different contrast agents such as superparamagnetic or paramagnetic nanoparticles, ultrasmall superparamagnetic nanoparticles, fluorine, gadolinium and some types of reporter genes have been used for imaging of stem cells. The core subject of these studies is to investigate the survival and differentiation of stem cells, contrast agent’s toxicity and long term following of transplanted cells. The promising results of in vivo and some clinical trial studies may raise hope for clinical stem cells imaging with MRI.

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        Synthesis of cationic polymeric adsorbent and dye removal isotherm, kinetic and thermodynamic

        Niyaz Mohammad Mahmoodi,Unes Sadeghi,Afshin Maleki,Bagher Hayati,Farhood Najafi 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.5

        Poly(quaternary ammonium salt) (PQAS) as a cationic polymeric adsorbent was synthesized and characterized by FTIR. Isotherm, kinetic and thermodynamic of dye removal from single and binary systems was investigated. Acid Blue 25 (AB25) and Acid Red 18 (AR18) were used. The effect of operational parameters (adsorbent dose, pH, dye concentration and salt) on dye removal was studied. The dye removal followed the Langmuir isotherm and pseudo-first order kinetics. The adsorbent maximum dye adsorption capacity (Q0) was 2000 and 1667 mg/g for AB25 and AR18, respectively. The thermodynamic data showed that dye adsorption was spontaneous, endothermic, and a physisorption reaction.

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        Assessment of Multi-leaf Collimator Positional Accuracy Using Radiochromic EBT3 Film and an Electronic Portal Imaging Device

        Forough Nikeghbali,Abolfazl Nickfarjam,Fateme Shirani,Nouraddin Abdi Goushbolagh,Nasim Namiranian,Bagher Farhood,Masoud Shabani,Kazem Vakili 한국물리학회 2020 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.76 No.9

        This study aimed to evaluate multi-leaf collimator (MLC) positional accuracy by using an electronic portal imaging device (EPID) and radiochromic EBT3 film. Furthermore, the MLC's positional accuracy at different gantry and collimator angles of a Siemens ONCOR linear accelerator (linac) was evaluated. A picket fence test was performed to evaluate the MLC's positional accuracy at various gantry and collimator angles of the linac. The EPID and the EBT3 films were sequentially irradiated seven times at 2-cm intervals by making a rectangular field (0.3 × 19 cm2). The full-width at half-maximum (FWHM) of each band (field) was calculated for all leaves by using inhouse software. Then, variations between the actual and the planned leaf locations were obtained by using the EPID and the EBT3 film at various gantry and collimator angles. The mean FWHM, acquired using the EPID and the EBT3 film ranged from 2.331 - 3.647 mm and 2.059 - 4.001 mm, respectively. Variations between the actual and the planned leaf locations were found to be affected by changes in the collimator and the gantry angles. Moreover, a -0.060 - 1.588 mm difference we seen between the result obtained from the EBT3 film and that obtained from the EPID. The mean FWHM, at most angles, for the EBT3 film was larger than that for the EPID. The findings showed average deviations for the EPID (0.001 - 0.669 mm) and EBT3 film (0.007 - 1.001 mm); these values agreed within the tolerance level (±1 mm). Furthermore, good agreement was found between the results obtained from the EPID and the EBT3 film; these two dosimetric methods can be used interchangeably, but each must be chosen considering its advantages and disadvantages.

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