Co-treatment Effect of Triadimefon and Salt Stress on Antioxidant Responses, NHX1 and LEA Expression in Two Alfalfa Cultivars (Medicago sativa L.) under in vitro Culture

Arab, Leila,Ehsanpour, Ali Akbar,Jwa, Nam Soo 한국응용생명화학회 2013 Applied Biological Chemistry (Appl Biol Chem) Vol.56 No.4

This study was carried out to investigate the possibility of using Triadimefon as a plant growth regulator and salt stress protectant in order to decrease the adverse effects of salt stress. Two Medicago cultivars including Hamedani and Yazdi were treated with 0, 2 mg/L triadimefon (TRD) and 0, 100, and 140 mM NaCl. Salt stress increased $Na^+$, ascorbic acid (AA), reduced glutathione (GSH), reactive oxygen species and phenol contents and activity of ascorbate peroxidase (APX), and glutathione reductase (GR), whereas decreased the $K^+$ content and the activity of polyphenol oxidase (PPO) in both cultivars. When plants were treated with TRD and NaCl, they accumulated less $Na^+$, $K^+$, and ROS. Co-treatment of NaCl and TRD in both cultivars increased AA, GSH, and phenol contents, and the activities of APX and GR, whereas reduced PPO activity. Our results also showed that LEA gene was up-regulated by salt stress. TRD treatment resulted in down-regulation of this gene. Sodium/hydrogen exchanger gene was not affected by either salt or TRD treatments.

Comparison of Two Ovarian Malignancy Prediction Models Based on Age Sonographic Findings and Serum Ca125 Measurement

Arab, Maliheh,Yaseri, Mehdi,Ashrafganjoi, Tahereh,Maktabi, Maryam,Noghabaee, Giti,Sheibani, Kourosh Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8

Objective: The aim of our study is to compare an ovarian malignancy prediction model based on age and four sonographic findings (OMPS1) with a new model called OMPS2 which differs just by adding serum CA125 measurement to (OMPS1). Methods: In a cross sectional comparative study OMPS1 was validated in 830 operated ovarian masses within a 3 years period (2006-2009). Logistic regression analysis was used to construct OMPS2 based on OMPS1 adding serum CA125 findings. The area under the curve for two models was compared in 411 patients. Results: OMPS2 was calculated as follows: OMPS1 + 1.444 (if serum CA125= 36-200) or 3.842 (if serum CA125 is more than 200). AUC of OMPS2 was increased to 84.3% (CI 95% 78.1- 89.8) in comparison to OMPS1 with AUC of 78.1% (CI 95% 71.8-84.5). Conclusion: Our second model is more accurate in prediction of ovarian malignancy, compared with our first model.

Long Noncoding RNA TARID Directs Demethylation and Activation of the Tumor Suppressor TCF21 via GADD45A

Arab, K.,Park, Y.,Lindroth, Anders M.,Schafer, A.,Oakes, C.,Weichenhan, D.,Lukanova, A.,Lundin, E.,Risch, A.,Meister, M.,Dienemann, H.,Dyckhoff, G.,Herold-Mende, C.,Grummt, I.,Niehrs, C.,Plass, C. Cell Press 2014 Molecular cell Vol.55 No.4

DNA methylation is a dynamic and reversible process that governs gene expression during development and disease. Several examples of active DNA demethylation have been documented, involving genome-wide and gene-specific DNA demethylation. How demethylating enzymes are targeted to specific genomic loci remains largely unknown. We show that an antisense lncRNA, termed TARID (for TCF21 antisense RNA inducing demethylation), activates TCF21 expression by inducing promoter demethylation. TARID interacts with both the TCF21 promoter and GADD45A (growth arrest and DNA-damage-inducible, alpha), a regulator of DNA demethylation. GADD45A in turn recruits thymine-DNA glycosylase for base excision repair-mediated demethylation involving oxidation of 5-methylcytosine to 5-hydroxymethylcytosine in the TCF21 promoter by ten-eleven translocation methylcytosine dioxygenase proteins. The results reveal a function of lncRNAs, serving as a genomic address label for GADD45A-mediated demethylation of specific target genes.

Synergistic Effect of Azadirachta Indica Extract and Iodide Ions on the Corrosion Inhibition of Aluminium in Acid Media

Arab, S.T.,Al-Turkustani, A.M.,Al-Dhahiri, R.H. Korean Chemical Society 2008 대한화학회지 Vol.52 No.3

Potintiodynamic 분광작용과 임피던스 기술을 이용하여 요드화 이온으로 Azadirachta Indica 엑스가 존재하는 0.5 M HCI용액 속의 Al 에 대한 부식 방지 작용을 상승시켰다. 이는 0.5 M HCI 용액에서 AZI 엑스가 Al의 부식을 방지함을 발견하였다. AZI 엑스 농도가 24% v/v이전에는 농도가 커짐에 따라 방지효율도 따라서 커진다. 하지만 AZI 엑스 농도가 더 커지면 Inh. %는 오히려 작아진다. 요드화 이온의 증가는 방지효율을 상당한 양으로 강화시킨다. 요드화 이온이 혼합적으로 존재할 때 Inh. %값은 증가한다. 이는 낮은 AZI 엑스 농도에서 AZI 엑스는 joint adsorption을 통하여 insoluble complex을 형성한다. 하지만 높은 AZI 엑스 농도에서는 요드화 이온과 형성한 complex사이에 competitive adsorption이 나타나 낮은 Inh. %를 초래한다. At all studied요드화 이온의 농도에서 요드화 이온과 AZI 엑스가 동시에 존재할 때의 Inh. %값은 AZI 엑스만 존재할 때보다 감소된다. Synergism parameter Sq는 표면 Coverage 값으로 계산된다. 이 Parameter는 AZI 엑스경우 unity 보다 더 큼을 알 수 있다. 이는 요드화 이온의 증가로 인하여 방지효율이 강화 되였음을 제시한다. synergistic action caused by iodide ions on the corrosion inhibition of aluminium (Al) in 0.5 M HCl in the presence of Azadirachta Indica (AZI) plant extract has been investigated using potintiodynamic polarization and impedance techniques. It is found that AZI extract inhibits the corrosion of aluminium in 0.5 M HCl. The inhibition efficiency increases with the increase in AZI extract concentration, until 24% v/v of AZI extract, then Inh.% is decreased with father increase in AZI extract concentration. The adsorption of this extract in the studied concentration is found to obey Frewendlish adsorption isotherm. The addition of iodide ions enhances the inhibition efficiency to a considerable extent. The increase in Inh.% values in presence of fixed concentration of iodide ions indicates that AZI extract forms an insoluble complex at lower AZI extract concentrations by undergoing a joint adsorption. But at higher concentrations of AZI extract, competitive adsorption is found between iodide ions and the formed complex leading to less Inh.%.The Inh.% decreased in presence of iodide ions with AZI extract than in presence of AZI extract alone at all studied iodide concentrations. The synergism parameter Sq is defined and calculated from surface coverage values. This parameter in the case of AZI extract is found to be more than unity, indicating that the enhanced inhibition efficiency caused by the addition of iodide ions.

Health-Related Quality of Life and its Associated Factors in COVID-19 Patients

Arab-Zozani Morteza,Hashemi Fatemah,Safari Hossein,Yousefi Mahmood,Ameri Hosein 질병관리본부 2020 Osong Public Health and Research Persptectives Vol.11 No.5

Objectives Health-related quality of life (HRQoL) is one of the most important outcome measures for patients. The purpose of this study was to evaluate HRQoL and related factors in Coronavirus disease 2019 (COVID-19) patients. Methods A total of 420 COVID-19 patients who had been discharged from hospital were selected using a systematic sampling. The EuroQol 5-dimensional-5 levels (EQ-5D-5L) questionnaire along with medical records of the patients were used to gather the data. The t test and analysis of variance were employed to test the difference between mean EQ-5D-5L scores, and the BetaMix model was used to investigate factors associated with EQ-5D-5L scores. Results The mean score for the patients who completed the EQ-5D-5L questionnaire (n = 409) was 0.6125. The EQ-5D-5L scores were significantly higher in males, patients with younger age, those with a low level of education, the employed, patients who worked in uncrowded workplaces, patients without diabetes, and those who were not admitted to intensive care unit. The BetaMix model showed that gender, age, education, employment status, having diabetes, heart failure, and admission to the intensive care unit were significant independent predictors of the EQ-5D-5L index values. Conclusion The mean score for EQ-5D-5L in COVID-19 patients was low in this study. Some of the factors, especially aging and having diabetes, should be considered in the aftercare of patients to improve their HRQoL.

Comparison of Crude and Age-Specific Incidence Rates of Breast, Ovary, Endometrium and Cervix Cancers in Iran, 2005

Arab, Maliheh,Noghabaei, Giti,Kazemi, Seyyedeh Neda Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6

Background: Cancer accounts for 12.6% of total deaths in the world (just after heart disease). Materials and Methods: Frequency and age-specific incidence rates of breast and gynecologic cancers in Iran are calculated based on the dataset of the National Cancer Registry of Iran in 2005. Results: Gynecologic and breast cancer accounted for 7.6% and 25.6% of total cancer cases, respectively. Ovarian cancer was the most frequent gynecologic cancer followed by endometrium. Endometrial cancer revealed the highest age specific incidence rate followed by ovary (after 59 years). Conclusions: Regarding disease burden, breast and gynecologic cases account for 33.4% of total cancer patients. The age specific incidence rate is a useful guide in epidemiologic and future plans.

Ovarian Malignancy Probability Score (OMPS) for Appropriate Referral of Adnexal Masses

Arab, Maliheh,Honarvar, Zahra,Hosseini-Zijoud, Seyed-Mostafa Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

Background: Ovarian cancer is the most common cancer cause of gynecologic cancer deaths. In order to increase the likelihood of patient survival through primary operation by gyneco-oncologists, an appropriate algorithm for referral is considered here. Materials and Methods: Suspicious adnexal mass cases including ovarian malignancy probability score-1 (OMPS1) scores between 2.3-3.65 are re-evaluated by OMPS2. Sensitivity and specificity of each score were determined. Results: Sensitivity and specificity with a 3.82 score of OMPS2 in the studied subgroup (OMPS1 scores between 2.3-3.65) were 64% and 76.9% respectively. Conclusions: Management of OMPS1 scores of below 2.3 with sensitivity of 100% and above 3.65 with specificity of 72.9% is clear. In the subgroup of cases with OMPS1 score between 2.3-3.65, OMPS2 is helpful for triage with a cutoff score of 3.82.

SOME FIXED POINT THEOREMS IN GENERALIZED DARBO FIXED POINT THEOREM AND THE EXISTENCE OF SOLUTIONS FOR SYSTEM OF INTEGRAL EQUATIONS

Arab, Reza Korean Mathematical Society 2015 대한수학회지 Vol.52 No.1

In this paper we introduce the notion of the generalized Darbo fixed point theorem and prove some fixed and coupled fixed point theorems in Banach space via the measure of non-compactness, which generalize the result of Aghajani et al. [6]. Our results generalize, extend, and unify several well-known comparable results in the literature. One of the applications of our main result is to prove the existence of solutions for the system of integral equations.

The Electrochemical Behavior of Ni-base Metallic Glasses Containing Cr in H₂SO₄ Solutions

Arab, Sanaa.T.,Emran, Khadijah.M.,Al-Turaif, Hamad A. Korean Chemical Society 2012 대한화학회지 Vol.56 No.4

In order to develop alloy resistance in aggressive sulphat ion, the corrosion behavior of metallic glasses $Ni_{92{\cdot}3}Si_{4.5}B_{32}$, $Ni_{82,3}Cr_7Fe_3Si_{4.5}B_{3.2}$ and $Ni_{75.5}Cr_{13}Fe_{4.2}Si_{4.5}B_{2.8}$ (at %) at different concentrations of $H_2SO_4$ solutions was examined by electrochemical methods and Scanning Electron Microscope (SEM) and X-ray Photoelectron Microscopy (XPS) analyses. The corrosion kinetics and passivation behavior was studied. A direct proportion was observed between the corrosion rate and acid concentration in the case of $Ni_{92{\cdot}3}Si_{4.5}B_{32}$ and $Ni_{75.5}Cr_{13}Fe_{4.2}Si_{4.5}B_{2.8}$ alloys. Critical concentration was observed in the case of $Ni_{82,3}Cr_7Fe_3Si_{4.5}B_{3.2}$ alloy. The influence of the alloying element is reflected in the increasing resistance of the protective film. XPS analysis confirms that the protection film on the $Ni_{92{\cdot}3}Si_{4.5}B_{32}$ alloy was NiS which is less protective than that formed on Cr containing alloys. The corrosion rate of $Ni_{82,3}Cr_7Fe_3Si_{4.5}B_{3.2}$ and $Ni_{75.5}Cr_{13}Fe_{4.2}Si_{4.5}B_{2.8}$. alloys containing 7% and 13% Cr are $7.90-26.1{\times}10^{-3}$ mm/y which is lower about 43-54 times of the alloy $Ni_{92{\cdot}3}Si_{4.5}B_{32}$ (free of Cr). The high resistance of $Ni_{75.5}Cr_{13}Fe_{4.2}Si_{4.5}B_{2.8}$ alloy at the very aggressive media may due to thicker passive film of $Cr_2O_3$ which hydrated to hydrated chromium oxyhydroxide.

Response of Stock (Matthiola incana L.) to Different Levels of Nitrogen and Potassium

Mostafa Arab,Amad Khalighi,Kazem Arzani,Roohangiz Naderi 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-