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- 저자 : Anil Arya (검색결과 3 건)
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Anil Arya,Achchhe Lal Sharma 한국고분자학회 2019 Macromolecular Research Vol.27 No.4
In the present paper, the temperature and salt-dependent dielectric properties of poly(ethylene oxide) (PEO) and poly(vinyl pyrrolidone) (PVP) blend matrix complexed with LiBOB are investigated in the frequency range 1 Hz to 1 MHz and temperature range 40 oC to 100 oC (@10 oC). The real and imaginary part of the complex permittivity, complex conductivity have been simulated in the whole frequency window and the various fitted parameters were evaluated respectively. The estimated value of the dielectric constant and the ac conductivity increases with the increase of temperature. The lowering of relaxation time and hopping length is observed with the salt addition that is in correlation with the complex conductivity results. The modulus formalism was used to analyze the recorded dielectric data. The dc conductivity, hopping frequency, and segmental motion are strongly coupled with each other as evidenced by the Debye-Stoke-Einstein (DSE) plot. An interaction mechanism has also been proposed to explore the effect of temperature on the hopping length, relaxation time, hopping potential barrier and the segmental motion of the polymer chain
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Deepak Kumar Jha,Anil Thakur,Mukul Jain,Arvind Arya,Chandrabhushan Tripathi,Rima Kumari,Suman Kushwaha 대한척추외과학회 2016 Asian Spine Journal Vol.10 No.6
Study Design: Prospective clinical study. Purpose: To observe the usefulness of anterior cervical osteophytes as intrinsic markers for spinal level localization (SLL) during sub-axial cervical spinal surgery via the anterior approach. Overview of Literature: Various landmarks, such as the mandibular angle, hyoid bone, thyroid cartilage, first cricoid ring, and C6 carotid tubercle, are used for gross cervical SLL; however, none are used during cervical spinal surgery via the anterior approach. We present our preliminary assessment of SLL over anterior vertebral surfaces (i.e., intrinsic markers) in 48 consecutive cases of anterior cervical spinal surgeries for the disc-osteophyte complex (DOC) in degenerative diseases and granulation or tumor tissue associated with infectious or neoplastic diseases, respectively, at an ill-equipped center. Methods: This prospective study on patients undergoing anterior cervical surgery for various sub-axial cervical spinal pathologies aimed to evaluate the feasibility and accuracy of SLL via intraoperative palpation of disease-related morphological changes on anterior vertebral surfaces visible on preoperative midline sagittal T1/2-weighted magnetic resonance images. Results: During a 3-year period, 48 patients (38 males,10 females; average age, 43.58 years) who underwent surgery via the anterior approach for various sub-axial cervical spinal pathologies, including degenerative disease (n= 42), tubercular infection (Pott’s disease; n=3), traumatic prolapsed disc (n=2), and a metastatic lesion from thyroid carcinoma (n=1), comprised the study group. Intrinsic marker palpation yielded accurate SLL in 79% of patients (n=38). Among those with degenerative diseases (n=42), intrinsic marker palpation yielded accurate SLL in 76% of patients (n=32). Conclusions: Intrinsic marker palpation is an attractive potential adjunct for SLL during cervical spinal surgeries via the anterior approach in well-selected patients at ill-equipped centers (e.g., those found in developing countries). This technique may prove helpful when radiographic visualization is occasionally inadequate.
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Morin ameliorates myocardial injury in diabetic rats via modulation of inflammatory pathways
Vipin Kumar Verma,Salma Malik,Ekta Mutneja,Anil Kumar Sahu,Vaishali Prajapati,Prashant Mishra,Jagriti Bhatia,Dharamveer Singh Arya 한국실험동물학회 2024 Laboratory Animal Research Vol.40 No.1
Background: High blood glucose levels in diabetes lead to vascular inflammation which accelerates atherosclerosis. Herein, Morin was orally administered in male Wistar rats, at the dose of 40 mg/kg for 28 days, and on the 27th and 28th day, ISO was administered to designate groups at the dose of 85 mg/kg s.c., to induce myocardial infarction. Results: Free radical generation, including ROS, in diabetes following ISO administration, leads to the activation of both intrinsic and extrinsic pathways of apoptosis. Morin significantly (p ≤ 0.05) reduced oxidative stress (GSH, MDA, SOD), cardiac injury markers (CK-MB, LDH), inflammation (TNF, IL-6), and apoptosis (Bax, BCl2, Caspase-3). In addition, it also reduced insulin and blood glucose levels. Akt/eNOS, Nrf2/HO-1, MAPK signaling pathways, and Insulin signal transduction pathways were positively modulated by morin pre-treatment. Conclusions: Morin attenuated oxidative stress and inflammation and also modified the activity of various molecular pathways to mitigate cardiomyocyte damage during ISO-induced MI in diabetic rats.
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