Cephalometric landmark variability among orthodontists and dentomaxillofacial radiologists: a comparative study

Ana Paula Reis Durão,Aline Morosolli,Pisha Pittayapat,Napat Bolstad,Afonso P. Ferreira,Reinhilde Jacobs 대한영상치의학회 2015 Imaging Science in Dentistry Vol.45 No.4

Purpose: The aim this study was to compare the accuracy of orthodontists and dentomaxillofacial radiologists in identifying 17 commonly used cephalometric landmarks, and to determine the extent of variability associated with each of those landmarks. Material and Methods: Twenty digital lateral cephalometric radiographs were evaluated by two groups of dental specialists, and 17 cephalometric landmarks were identified. The x and y coordinates of each landmark were recorded. The mean value for each landmark was considered the best estimate and used as the standard. Variation in measurements of the distance between landmarks and measurements of the angles associated with certain landmarks was also assessed by a subset of two observers, and intraobserver and interobserver agreement were evaluated. Results: Intraclass correlation coefficients were excellent for intraobserver agreement, but only good for interobserver agreement. The least reliable landmark for orthodontists was the gnathion (Gn) point (standard deviation [SD], 5.92 mm), while the orbitale (Or) was the least reliable landmark (SD, 4.41 mm) for dentomaxillofacial radiologists. Furthermore, the condylion (Co)-Gn plane was the least consistent (SD, 4.43 mm). Conclusions: We established that some landmarks were not as reproducible as others, both horizontally and vertically. The most consistently identified landmark in both groups was the lower incisor border, while the least reliable points were Co, Gn, Or, and the anterior nasal spine. Overall, a lower level of reproducibility in the identification of cephalometric landmarks was observed among orthodontists.

Cephalometric landmark variability among orthodontists and dentomaxillofacial radiologists: a comparative study

Durao, Ana Paula Reis,Morosolli, Aline,Pittayapat, Pisha,Bolstad, Napat,Ferreira, Afonso P.,Jacobs, Reinhilde Korean Academy of Oral and Maxillofacial Radiology 2015 Imaging Science in Dentistry Vol.45 No.4

Purpose: The aim this study was to compare the accuracy of orthodontists and dentomaxillofacial radiologists in identifying 17 commonly used cephalometric landmarks, and to determine the extent of variability associated with each of those landmarks. Materials and Methods: Twenty digital lateral cephalometric radiographs were evaluated by two groups of dental specialists, and 17 cephalometric landmarks were identified. The x and y coordinates of each landmark were recorded. The mean value for each landmark was considered the best estimate and used as the standard. Variation in measurements of the distance between landmarks and measurements of the angles associated with certain landmarks was also assessed by a subset of two observers, and intraobserver and interobserver agreement were evaluated. Results: Intraclass correlation coefficients were excellent for intraobserver agreement, but only good for interobserver agreement. The least reliable landmark for orthodontists was the gnathion (Gn) point (standard deviation [SD], 5.92 mm), while the orbitale (Or) was the least reliable landmark (SD, 4.41 mm) for dentomaxillofacial radiologists. Furthermore, the condylion (Co)-Gn plane was the least consistent (SD, 4.43 mm). Conclusion: We established that some landmarks were not as reproducible as others, both horizontally and vertically. The most consistently identified landmark in both groups was the lower incisor border, while the least reliable points were Co, Gn, Or, and the anterior nasal spine. Overall, a lower level of reproducibility in the identification of cephalometric landmarks was observed among orthodontists.

Calcium phosphates and silicon: exploring methods of incorporation

Ana I. Rodrigues,Rui L. Reis,Clemens A. van Blitterswijk,Isabel B. Leonor,Pamela Habibović 한국생체재료학회 2017 생체재료학회지 Vol.21 No.2

Background: Bioinorganics have been explored as additives to ceramic bone graft substitutes with the aim to improve their performance in repair and regeneration of large bone defects. Silicon (Si), an essential trace element involved in the processes related to bone formation and remodeling, was shown not only to enhance osteoblasts proliferation but also to stimulate the differentiation of mesenchymal stem cells (MSCs) and preosteoblasts into the osteogenic lineage. In this study, the added value of Si to calcium phosphate (CaP) coatings was evaluated. Methods: Tissue culture plastic well plates were coated with a thin CaP layer to which traces amounts of Si were added, either by adsorption or by incorporation through coprecipitation. The physicochemical and structural properties of the coatings were characterized and the dissolution behavior was evaluated. The adsorption/incorporation of Si was successfully achieved and incorporated ions were released from the CaP coatings. Human MSCs were cultured on the coatings to examine the effects of Si on cell proliferation and osteogenic differentiation. For the statistical analysis, a one-way ANOVA with Bonferroni post-hoc test was performed. Results: The results showed that human MSCs (hMSCs) responded to the presence of Si in the CaP coatings, in a dosedependent manner. An increase in the expression of markers of osteogenic differentiation by human MSCs was observed as a result of the increase in Si concentration. Conclusions: The incorporation/adsorption of Si into CaP coatings was successfully achieved and hMSCs responded with an increase in osteogenic genes expression with the increase of Si concentration. Furthermore, hMSCs cultured on CaP-I coatings expressed higher levels of ALP and OP, indicating that this may be the preferred method of incorporation of bioinorganics into CaPs.

Adhesion of biofilm, surface characteristics, and mechanical properties of antimicrobial denture base resin

Ana Beatriz Vilela Teixeira,Mariana Lima da Costa Valente,João Pedro Nunes Sessa,Bruna Gubitoso,Marco Antonio Schiavon,Andréa Cândido dos Reis 대한치과보철학회 2023 The Journal of Advanced Prosthodontics Vol.15 No.2

PURPOSE. This study incorporated the nanomaterial, nanostructured silver vanadate decorated with silver nanoparticles (AgVO3), into heat-cured resin (HT) at concentrations of 2.5%, 5%, and 10% and compared the adhesion of multispecies biofilms, surface characteristics, and mechanical properties with conventional heat-cured (HT 0%) and printed resins. MATERIALS AND METHODS. AgVO3 was incorporated in mass into HT powder. A denture base resin was used to obtain printed samples. Adhesion of a multispecies biofilm of Candida albicans, Candida glabrata, and Streptococcus mutans was evaluated by colony-forming units per milliliter (CFU/mL) and metabolic activity. Wettability, roughness, and scanning electron microscopy (SEM) were used to assess the physical characteristics of the surface. The mechanical properties of flexural strength and elastic modulus were tested. RESULTS. HT 10%-AgVO3 showed efficacy against S. mutans; however, it favored C. albicans CFU/mL (P < .05). The printed resin showed a higher metabolically active biofilm than HT 0% (P < .05). There was no difference in wettability or roughness between groups (P > .05). Irregularities on the printed resin surface and pores in HT 5%-AgVO3 were observed by SEM. HT 0% showed the highest flexural strength, and the resins incorporated with AgVO3 had the highest elastic modulus (P < .05). CONCLUSION. The incorporation of 10% AgVO3 into heat-cured resin provided antimicrobial activity against S. mutans in a multispecies biofilm did not affect the roughness or wettability but reduced flexural strength and increased elastic modulus. Printed resin showed higher irregularity, an active biofilm, and lower flexural strength and elastic modulus than heat-cured resin. [J Adv Prosthodont 2023;15:80-92]

IN SITU HYBRIDIZATION (ISH) WITH BIOTINYLATED PROBES AND KIT FOR THE DIAGNOSIS OF Batrachochytrium dendrobatidis IN MOUTH OF BULLFROG TADPOLES (Lithobates catesbeianus). EXPERIMENTAL RESULTS

Marcio Hipolito,Ana M. Cristina. R.P.F. Martin,Luara.L. Cassiano,Adriana dos Reis,Claudia.M. Ferreira 한국수산과학회 양식분과 2015 한국수산과학회 양식분과 학술대회 Vol.2015 No.5

Effectiveness and safety of rotary and reciprocating kinematics for retreatment of curved root canals: a systematic review of in vitro studies

Simões Lucas Pinho,Reis-Prado Alexandre Henrique dos,Bueno Carlos Roberto Emerenciano,Viana Ana Cecília Diniz,Duarte Marco Antônio Húngaro,Cintra Luciano Tavares Angelo,Lemos Cleidiel Aparecido Araújo 대한치과보존학회 2022 Restorative Dentistry & Endodontics Vol.47 No.2

Objectives This systematic review (register-osf.io/wg7ba) compared the efficacy and safety of rotary and reciprocating kinematics in the removal of filling material from curved root canals. Materials and Methods Only in vitro studies evaluating both kinematics during retreatment were included. A systematic search (PubMed/MEDLINE, Scopus, and other databases, until January 2021), data extraction, and risk of bias analysis (Joanna Briggs Institute checklist) were performed. Efficacy in filling removal was the primary outcome. Results The search resulted in 2,795 studies, of which 15 were included. Efficacy was measured in terms of the remaining filling material and the time required for this. Nine studies evaluated filling material removal, of which 7 found no significant differences between rotary and reciprocating kinematics. Regarding the time for filling removal, 5 studies showed no difference between both kinematics, 2 studies showed faster results with rotary systems, and other 2 showed the opposite. No significant differences were found in apical transportation, centering ability, instrument failure, dentin removed and extruded debris. A low risk of bias was observed. Conclusions This review suggests that the choice of rotary or reciprocating kinematics does not influence the efficacy of filling removal from curved root canals. Further studies are needed to compare the kinematics safety in curved root canals. Objectives This systematic review (register-osf.io/wg7ba) compared the efficacy and safety of rotary and reciprocating kinematics in the removal of filling material from curved root canals. Materials and Methods Only in vitro studies evaluating both kinematics during retreatment were included. A systematic search (PubMed/MEDLINE, Scopus, and other databases, until January 2021), data extraction, and risk of bias analysis (Joanna Briggs Institute checklist) were performed. Efficacy in filling removal was the primary outcome. Results The search resulted in 2,795 studies, of which 15 were included. Efficacy was measured in terms of the remaining filling material and the time required for this. Nine studies evaluated filling material removal, of which 7 found no significant differences between rotary and reciprocating kinematics. Regarding the time for filling removal, 5 studies showed no difference between both kinematics, 2 studies showed faster results with rotary systems, and other 2 showed the opposite. No significant differences were found in apical transportation, centering ability, instrument failure, dentin removed and extruded debris. A low risk of bias was observed. Conclusions This review suggests that the choice of rotary or reciprocating kinematics does not influence the efficacy of filling removal from curved root canals. Further studies are needed to compare the kinematics safety in curved root canals.

Evaluation of Women with Myofascial Abdominal Syndrome Based on Traditional Chinese Medicine

Mitidieri, Andreia,Gurian, Maria Beatriz,Silva, Ana Paula,Tawasha, Kalil,Poli-Neto, Omero,Nogueira, Antonio,Reis, Francisco,Rosa-e-Silva, Julio KOREAN PHARMACOPUNCTURE INSTITUTE 2015 Journal of pharmacopuncture Vol.18 No.4

Objectives: This study used semiology based on traditional Chinese medicine (TCM) to investigate vital energy (Qi) behavior in women with abdominal myofascial pain syndrome (AMPS). Methods: Fifty women diagnosed with chronic pelvic pain (CPP) secondary to AMPS were evaluated by using a questionnaire based on the theories of "yin-yang," "zang-fu", and "five elements". We assessed the following aspects of the illness: symptomatology; specific location of myofascial trigger points (MTrPs); onset, cause, duration and frequency of symptoms; and patient and family history. The patients tongues, lips, skin colors, and tones of speech were examined. Patients were questioned on various aspects related to breathing, sweating, sleep quality, emotions, and preferences related to color, food, flavors, and weather or seasons. Thirst, gastrointestinal dysfunction, excreta (feces and urine), menstrual cycle, the five senses, and characteristic pain symptoms related to headache, musculoskeletal pain, abdomen, and chest were also investigated. Results: Patients were between 22 and 56 years old, and most were married (78%), possessed a elementary school (66%), and had one or two children (76%). The mean body mass index and body fat were 26.86 kg/cm2 (range: 17.7 - 39.0) and 32.4% (range: 10.7 - 45.7), respectively. A large majority of women (96%) exhibited alterations in the kidney meridian, and 98% had an altered gallbladder meridian. We observed major changes in the kidney and the gallbladder Qi meridians in 76% and 62% of patients, respectively. Five of the twelve meridians analyzed exhibited Qi patterns similar to pelvic innervation Qi and meridians, indicating that the paths of some of these meridians were directly related to innervation of the pelvic floor and abdominal region. Conclusion: The women in this study showed changes in the behavior of the energy meridians, and the paths of some of the meridians were directly related to innervation of the pelvic floor and abdominal region.

Effect of endodontic sealer on postoperative pain: a network meta-analysis

Monteiro Cynthia Maria Chaves,Martins Ana Cristina Rodrigues,Reis Alessandra,de Geus Juliana Larocca 대한치과보존학회 2023 Restorative Dentistry & Endodontics Vol.48 No.1

This systematic review and network meta-analysis aimed to answer the following focused research question: “Does the type of endodontic sealer affect the postoperative pain in patients who received endodontic treatment?” Different databases and grey literature were surveyed. Only one randomized controlled trial were included. The risk of bias in the studies was evaluated by using the Cochrane Collaboration’s tool. A random-effects meta-analysis was conducted to compare the risk and intensity of postoperative pain. The quality of the body of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation approach. Out of 11,601 studies, 15 remained for qualitative analyses and 12 for meta-analysis. Seven studies were classified at high risk of bias, and 8 studies raised some concerns. No significant differences between the endodontic materials were observed in the direct comparisons, both in risk and in intensity of postoperative pain (pairwise comparisons with 2 studies: I2 = 0%; p > 0.05 and 8 studies: I2 = 23%; p > 0.05, respectively). The certainty of the evidence was graded as low or moderate. There was no difference in the risk and intensity of postoperative pain after filling with different endodontic sealers. Further systematic reviews should be conducted.

Evaluation of Women with Myofascial Abdominal Syndrome Based on Traditional Chinese Medicine

Andréia Mitidieri,Maria Beatriz Gurian,Ana Paula Silva,Kalil Tawasha,Omero Poli-Neto,Antônio Nogueira,Francisco Reis,Júlio Rosa-e-Silva 대한약침학회 2015 Journal of pharmacopuncture Vol.18 No.4

Objectives: This study used semiology based on traditionalChinese medicine (TCM) to investigate vital energy(Qi) behavior in women with abdominal myofascialpain syndrome (AMPS). Methods: Fifty women diagnosed with chronic pelvicpain (CPP) secondary to AMPS were evaluated by usinga questionnaire based on the theories of “yin-yang,”“zang-fu”, and “five elements”. We assessed the followingaspects of the illness: symptomatology; specific locationof myofascial trigger points (MTrPs); onset, cause, durationand frequency of symptoms; and patient and familyhistory. The patients tongues, lips, skin colors, and tonesof speech were examined. Patients were questioned onvarious aspects related to breathing, sweating, sleepquality, emotions, and preferences related to color, food,flavors, and weather or seasons. Thirst, gastrointestinaldysfunction, excreta (feces and urine), menstrual cycle,the five senses, and characteristic pain symptoms relatedto headache, musculoskeletal pain, abdomen, andchest were also investigated. Results: Patients were between 22 and 56 years old,and most were married (78%), possessed a elementaryschool (66%), and had one or two children (76%). Themean body mass index and body fat were 26.86 kg/cm2(range: 17.7 — 39.0) and 32.4% (range: 10.7 — 45.7), respectively. A large majority of women (96%) exhibitedalterations in the kidney meridian, and 98% hadan altered gallbladder meridian. We observed majorchanges in the kidney and the gallbladder Qi meridiansin 76% and 62% of patients, respectively. Five of thetwelve meridians analyzed exhibited Qi patterns similarto pelvic innervation Qi and meridians, indicatingthat the paths of some of these meridians were directlyrelated to innervation of the pelvic floor and abdominalregion. Conclusion: The women in this study showed changesin the behavior of the energy meridians, and the pathsof some of the meridians were directly related to innervationof the pelvic floor and abdominal region.

Pharmacological Treatment of Acute Unilateral Vestibulopathy: A Review

Sousa Francisco Alves de,Alves Clara Serdoura,Pinto Ana Nóbrega,Meireles Luís,Rego Ângela Reis 대한청각학회 2024 Journal of Audiology & Otology Vol.28 No.1

There have been few investigations on the epidemiology, etiology, and medical management of acute unilateral vestibulopathy (AUV). Short-term pharmaceutical resolutions include vestibular symptomatic suppressants, anti-emetics, and some cause-based therapies. Anticholinergics, phenothiazines, antihistamines, antidopaminergics, benzodiazepines, and calcium channel antagonists are examples of vestibular suppressants. Some of these medications may show their effects through multiple mechanisms. In contrast, N-acetyl-L-leucine, Ginkgo biloba, and betahistine improve central vestibular compensation. Currently, AUV pathophysiology is poorly understood. Diverse hypotheses have previously been identified which have brought about some causal treatments presently used. According to some publications, acute administration of anti-inflammatory medications may have a deleterious impact on both post-lesional functional recovery and endogenous adaptive plasticity processes. Thus, some authors do not recommend the use of corticosteroids in AUV. Antivirals are even more contentious in the context of AUV treatment. Although vascular theories have been presented, no verified investigations employing anti-clotting or vasodilator medications have been conducted. There are no standardized treatment protocols for AUV to date, and the pharmacological treatment of AUV is still questionable. This review addresses the most current developments and controversies in AUV medical treatment.