Black hole elasticity and gapped transverse phonons in holography

Alberte, Lasma,Ammon, Martin,Baggioli, Matteo,Jimé,nez, Amadeo,Pujolà,s, Oriol Institute of Physics Pub 2018 The journal of high energy physics Vol.2018 No.1

Pro-Inflammatory Enzymes, Cyclooxygenase 1, Cyclooxygenase 2, and 5-Lipooxygenase, Inhibited by Stabilized Rice Bran Extracts

Bill Roschek Jr.,Ryan C. Fink,Dan Li,Matthew McMichael,Christine M. Tower,Robert D. Smith,Randall S. Alberte 한국식품영양과학회 2009 Journal of medicinal food Vol.12 No.3

Rice bran, the outer bran and germ of the kernel and a by-product of rice milling, is rich in phytonutrients but has been underutilized because of lipid content instability. New methods for the processing of rice bran have yielded a stabilized form that is increasingly used in foods and dietary supplements. Recent studies have documented a role for stabilized rice bran (SRB) in treating diabetes and arthritis, although little is known of the bioactive compounds that impart these health benefits. Here we characterize the chemical composition of three extracts of SRB and identify the functional bioactives contributing to the inhibitory properties against three key pro-inflammatory enzymes (cyclooxygenase [COX] 1, COX2, and 5-lipoxygenase [5-LOX]) that control the inflammatory cascade involved in impaired joint health, pain, and arthritis. One extract (SRB-AI) demonstrated significant COX1 and COX2 inhibitory activities with 50% inhibitory concentration (IC50) values for COX1 and COX2 of 305 and 29μg/mL, respectively, but no 5-LOX inhibition. The second extract (SRB-AII) inhibited COX1, COX2, and 5-LOX with IC50 values of 310, 19, and 396μg/mL, respectively. The third extract (SRB-AIII), a blend of SRB-AI and SRB-AIII, inhibited COX1, COX2, and 5-LOX with respective IC50 values of 48, 11, and 197μg/mL. Analysis of the extracts by direct analysis in real time time of flight-mass spectrometry revealed that SRB-AI, SRB-AII, and SRB-AIII contain over 620, 770, and 810 compounds, respectively. Of these, 17 were identified as key bioactives for COX and/or LOX inhibition. These SRB extracts have applications for functional foods and dietary supplements for control of inflammation and joint health.

Pro-Inflammatory Enzymes, Cyclooxygenase 1, Cyclooxygenase 2, and 5-Lipooxygenase, Inhibited by Stabilized Rice Bran Extracts

Roschek, Bill Jr.,Fink, Ryan C.,McMichael, Dan Li, Matthew,Tower, Christine M.,Smith, Robert D.,Alberte, Randall S. The Korean Society of Food Science and Nutrition 2009 Journal of medicinal food Vol.12 No.3

Rice bran, the outer bran and germ of the kernel and a by-product of rice milling, is rich in phytonutrients but has been underutilized because of lipid content instability. New methods for the processing of rice bran have yielded a stabilized form that is increasingly used in foods and dietary supplements. Recent studies have documented a role for stabilized rice bran (SRB) in treating diabetes and arthritis, although little is known of the bioactive compounds that impart these health benefits. Here we characterize the chemical composition of three extracts of SRB and identify the functional bioactives contributing to the inhibitory properties against three key pro-inflammatory enzymes (cyclooxygenase [COX] 1, COX2, and 5-lipoxygenase [5-LOX]) that control the inflammatory cascade involved in impaired joint health, pain, and arthritis. One extract (SRB-AI) demonstrated significant COX1 and COX2 inhibitory activities with 50% inhibitory concentration ($IC_{50}$) values for COX1 and COX2 of 305 and $29\;{\mu}g/mL$, respectively, but no 5-LOX inhibition. The second extract (SRB-AII) inhibited COX1, COX2, and 5-LOX with $IC_{50}$ values of 310, 19, and $396\;{\mu}g/mL$, respectively. The third extract (SRB-AIII), a blend of SRB-AI and SRB-AIII, inhibited COX1, COX2, and 5-LOX with respective $IC_{50}$ values of 48, 11, and $197\;{\mu}g/mL$. Analysis of the extracts by direct analysis in real time time of flight-mass spectrometry revealed that SRB-AI, SRB-AII, and SRB-AIII contain over 620, 770, and 810 compounds, respectively. Of these, 17 were identified as key bioactives for COX and/or LOX inhibition. These SRB extracts have applications for functional foods and dietary supplements for control of inflammation and joint health.

Web-based CAD/CAM/CAE Pedagogy Combining Domain-Knowledge and E-learning Models with Bezier curve Generation as a Case Study

Yin-Tung ”Albert” Sun,Mike A. Perez 대한산업공학회 2003 Industrial Engineeering & Management Systems Vol.2 No.2

Review of Basics Reverse Osmosis Process Modeling: A New Combined Fouling Index Proposed

Albert S. Kim 한국막학회 2017 멤브레인 Vol.27 No.4

Seawater desalination is currently considered to be one of the primary technologies to resolve the global water scarcity problem. A basic understanding of membrane filtration phenomena is significant not only for further technological development but also for integrated design, optimal control, and long-term maintenance. In this vein, the present work reviews the major transport and filtration models, specifically related to reverse osmosis phenomena, provides theoretical insights based on statistical mechanics, and discusses model-based physical meanings as related to their practical implications.

Search for high-energy neutrinos from gravitational wave event GW151226 and candidate LVT151012 with ANTARES and IceCube

Albert, A.,André,, M.,Anghinolfi, M.,Anton, G.,Ardid, M.,Aubert, J.-J.,Avgitas, T.,Baret, B.,Barrios-Martí,, J.,Basa, S.,Bertin, V.,Biagi, S.,Bormuth, R.,Bourret, S.,Bouwhuis, M. C.,Bruijn American Physical Society 2017 Physical review. D Vol.96 No.2

<P>The Advanced LIGO observatories detected gravitational waves from two binary black hole mergers during their first observation run (O1). We present a high-energy neutrino follow-up search for the second gravitational wave event, GW151226, as well as for gravitational wave candidate LVT151012. We find two and four neutrino candidates detected by IceCube, and one and zero detected by ANTARES, within +/- 500 s around the respective gravitational wave signals, consistent with the expected background rate. None of these neutrino candidates are found to be directionally coincident with GW151226 or LVT151012. We use nondetection to constrain isotropic-equivalent high-energy neutrino emission from GW151226, adopting the GW event's 3D localization, to less than 2 x 10(51)-2 x 10(54) erg.</P>

The Role of Business Capabilities in Supporting Organization Agility and Performance During the COVID-19 Pandemic: An Empirical Study in Indonesia

Albert Surya WANASIDA,Innocentius BERNARTO,Niko SUDIBJO,Agus PURWANTO 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.5

This study aims to analyze the important role of business analytics capability, information quality, and innovation capability in influencing organization agility and organization performance during the Covid-19 pandemic. Data was collected from 76 companies from various sectors in Indonesia. Structural Equation Model-Partial Least Square (SEM-PLS) analysis was conducted to analyze the relationship between variables and test a series of hypotheses. Importance-Performance Matrix Analysis (IPMA), a useful analysis approach in PLS-SEM, is used, which extends the results of the estimated path coefficient (importance) by adding a dimension that considers the average values of the latent variable scores (performance). The IPMA approach examines not only the performance of an item but also the importance of that item. The results show that business analytics capability has a significant effect on information quality and innovation capability which then affects organization agility. Organizational performance is influenced by organizational agility. IPMA results show that organizational agility has the highest level of impact on organizational performance. This study will assist companies in planning business analytics, improving information quality, increasing innovation capability, and ultimately increasing agility and performance during the Covid-19 pandemic. This study will add to existing knowledge about previous literature, especially in the Covid-19 pandemic situation.

역삼투 공정을 위한 모델링 총설 및 새로운 복합적 막오염도의 제안

Albert S. Kim 한국막학회 2017 멤브레인 Vol.27 No.4

해수담수화는 최근 전 세계적으로 대두되고 있는 물부족 현상을 해결하기 위한 최적 기술 중 하나이다. 막분리 및 투과 현상의 근본적인 이해는 차후의 막여과 기술의 발전을 위해서 뿐만 아니라, 현재 막기술 증진을 위한 통합적 디자인, 최적화 제어법, 그리고 중장기적 유지관리를 위해서도 매우 중요하다. 이에, 본 연구는 물질 전달 및 여과 현상에 대한 기존 의 주요 모델들을 상세히 재검토하고, 통계물리학에 근간하여 주요 막분리 현상들을 이론적으로 분석하며, 원천적 모델에 기 초한 물리적 의미와 그들이 실제 막공정에서 미치는 영향들에 대해서 함축적으로 토의하고자 한다. 이론적 재검토의 과정에 서 새로이 유도된 복합적 막오염도(Combined Fouling Index (CFI))의 소개도 포함한다. Seawater desalination is currently considered to be one of the primary technologies to resolve the global water scarcity problem. A basic understanding of membrane filtration phenomena is significant not only for further technological development but also for integrated design, optimal control, and long-term maintenance. In this vein, the present work reviews the major transport and filtration models, specifically related to reverse osmosis phenomena, provides theoretical insights based on statistical mechanics, and discusses model-based physical meanings as related to their practical implications.

Efficiency of stiffening plates in fabricated concrete-filled tubes under monotonic compression

Albert Albareda-Valls,Jordi Maristany Carreras 국제구조공학회 2015 Steel and Composite Structures, An International J Vol.18 No.4

Concrete-filled tubes (CFT), formed by an outer steel tube filled with plain or reinforced concrete inside, have been increasingly used these recent decades as columns or beam-columns, especially for tall buildings in seismic areas due to their excellent structural response. This improved behavior is derived from the effect of confinement provided by the tube, since the compressive strength of concrete increases when being subjected to hydrostatic pressure. In circular CFTs under compression, the whole tube is uniformly tensioned due to the radial expansion of concrete. Contrarily, in rectangular and square-shaped CFTs, the lateral flanges become subjected to in-plane bending derived from this volumetric expansion, and this fact implies a reduction of the confinement effect of the core. This study presents a numerical analysis of different configurations of CFT stub columns with inner stiffening plates, limited to the study of the influence of these plates on the compressive behavior without eccentricity. The final purpose is to evaluate the efficiency in terms of strength and ductility of introducing stiffeners into circular and square CFT sections under large deformation axial loading.

Neutrophil Gelatinase-Associated Lipocalin Cutoff Value Selection and Acute Kidney Injury Classification System Determine Phenotype Allocation and Associated Outcomes

Albert Annemarie,Radtke Sebastian,Blume Louisa,Bellomo Rinaldo,Haase Michael,Stieger Philipp,Hinkel Ulrich Paul,Braun-Dullaeus Rüdiger C.,Albert Christian 대한진단검사의학회 2023 Annals of Laboratory Medicine Vol.43 No.6

Background: We explored the extent to which neutrophil gelatinase-associated lipocalin (NGAL) cutoff value selection and the acute kidney injury (AKI) classification system determine clinical AKI-phenotype allocation and associated outcomes. Methods: Cutoff values from ROC curves of data from two independent prospective cardiac surgery study cohorts (Magdeburg and Berlin, Germany) were used to predict Kidney Disease: Improving Global Outcome (KDIGO)- or Risk, Injury, Failure, Loss of kidney function, End-stage (RIFLE)-defined AKI. Statistical methodologies (maximum Youden index, lowest distance to [0, 1] in ROC space, sensitivity≈specificity) and cutoff values from two NGAL meta-analyses were evaluated. Associated risks of adverse outcomes (acute dialysis initiation and in-hospital mortality) were compared. Results: NGAL cutoff concentrations calculated from ROC curves to predict AKI varied according to the statistical methodology and AKI classification system (10.6–159.1 and 16.85–149.3 ng/mL in the Magdeburg and Berlin cohorts, respectively). Proportions of attributed subclinical AKI ranged 2%–33.0% and 10.1%–33.1% in the Magdeburg and Berlin cohorts, respectively. The difference in calculated risk for adverse outcomes (fraction of odds ratios for AKI-phenotype group differences) varied considerably when changing the cutoff concentration within the RIFLE or KDIGO classification (up to 18.33- and 16.11-times risk difference, respectively) and was even greater when comparing cutoff methodologies between RIFLE and KDIGO classifications (up to 25.7-times risk difference). Conclusions: NGAL positivity adds prognostic information regardless of RIFLE or KDIGO classification or cutoff selection methodology. The risk of adverse events depends on the methodology of cutoff selection and AKI classification system.