Diagnostic and Therapeutic Capability of Double-Balloon Enteroscopy in Clinical Practice

Umit Akyuz,Filiz Akyuz 대한소화기내시경학회 2016 Clinical Endoscopy Vol.49 No.2

Advances in technology have facilitated the common use of small-bowel imaging. Intraoperative enteroscopy was the gold standard method for small-bowel imaging. However, noninvasive capsule endoscopy and invasive balloon enteroscopy are currently the main endoscopic procedures that are routinely used for small-bowel pathologies, and the indications for both techniques are similar. Although obstruction is a contraindication for capsule endoscopy, it is not considered to be problematic for double-balloon enteroscopy. The most important advantage of double-balloon enteroscopy is the applicability of therapeutic interventions during the procedure; however, double-balloon enteroscopy has certain advantages as well as disadvantages.

Revisiting the Long-Run Relationship Between Inward/Outward FDI and Income Inequality: New Evidence from the OECD

Akyuz Mert,Gueye Ghislain Nono,Karul Cagin 한국국제경제학회 2023 International Economic Journal Vol.37 No.2

The relatively small panel cointegration literature on the dynam- ics between FDI and income inequality predominantly finds that FDI will reduce income inequality in the long-run in developed countries. However, we point out an important technical oversight in the literature. Not accounting for cross-section dependence in panel data methodologies may yield unreliable results. Expanding on the work of Herzer and Nunnenkamp [(2013). Inward and out- ward FDI and income inequality: Evidence from Europe. Review of World Economics, 149(2), 395–422. https://doi.org/10.1007/s10290- 013-0148-3], who pioneered the use of panel cointegration in the European context, we obtain different results when we account for cross-section dependence and employ economic procedures robust to it. Using a panel containing 16 OECD countries (1979–2017), 2 income inequality measures, and 4 FDI measures, we begin by show- ing strong evidence for the existence of cross-section dependence. Then, using second-generation econometric procedures, we do not find any evidence for a cointegrating relationship between inward FDI and income inequality. We do find evidence that outward FDI is cointegrated with income inequality; however, contrary to the main results of the literature, we find that it widens the income gap in the long-run. Additionally, our results support the view that fiscal policy is an important tool to reduce income inequality.

Sleep Quality in Lung Cancer Patients

Akyuz, Ruveyda Gelisken,Ugur, Ozlem,Elcigil, Ayfer Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

Background: The aim of this study was to determine factors affecting sleep quality of 100 patients with advanced stage lung cancer. Methods and Results: it was a descriptive study. A variety of assessment tools were used to provide sleep scores to examine the relation between adverse effects caused by the treatment (nausea, vomiting, fatigue) and sleep quality. As a result, no statistically significant relation between coughing and respiratory problems of patients, or existing depression, and average sleep quality score was found (KW:0.872, p=0.646, KW: 3.174, p=0.205, u: 441.000 p=0.916). It was revealed that nausea and loss of appetite experienced also did not affect the sleep quality score (p>0.05), whereas problems such as vomiting and fatigue did exert effects (p<0.01). Conclusions: Patients with advanced stage lung cancer suffer from sleep problems and cancer related symptoms also affect their sleep quality negatively. Nurses should plan interventions that can control symptoms such as pain, vomiting and fatigue, which affect the sleep of patients.

Spontaneous Coronary Artery Dissection and Woven Coronary Artery: Three Cases and a Review of the Literature

Aydın Akyuz,Seref Alpsoy,Dursun Cayan Akkoyun 대한심장학회 2013 Korean Circulation Journal Vol.43 No.6

Spontaneous coronary artery dissection (SCAD) and woven coronary artery anomaly (WCAA) are relatively rare. A few of the previously reported woven coronary artery cases have involved in a single coronary artery. We present an unusual woven case involving all coronary arteries and two patient with SCAD. We have also reviewed the literature related to these disease, as they resemble one another.

Maximal Exercise-Corrected QT as a Predictor of Coronary Artery Disease: Comparison of Simpler Heart Rate Corrections

Aydın Akyuz,Seref Alpsoy,Dursun Cayan Akkoyun,Hasan Degirmenci,Niyazi Guler 대한심장학회 2013 Korean Circulation Journal Vol.43 No.10

Background and Objectives: The relationship between QT prolongation and myocardial ischemia is widely known. Due to the limited value of ST depression, we aimed to evaluate, by using four simpler heart rate corrections (Bazett, Framingham, Fridericia and Hodges), the value of maximal exercise-QTc prolongation in the diagnosis of coronary artery disease (CAD) presence and severity. Subjects and Methods: We enrolled 234 subjects (mean age 57.3±9 years, 143 men) who had undergone exercise testing and coronary angiography due to a suspicion of CAD in the study. Evaluating CAD severity with Gensini scoring, the CAD group (n=122) and controls with non-CAD were compared in terms of corrected QT duration at maximal exercise. Results: Age, gender, hypertension, dyslipidemia, smoking, exercise duration, resting, and peak heart rate were similar between the two groups (all p>0.05). The CAD group had higher raw QT values than the controls {268 (169-438) vs. 240 (168-348), p<0.001}. Although Fra-mingham QTc of ≥350 ms and Fridericia QTc of ≥340 ms were seen to be useful for the diagnosis of CAD, there was no additive diagnostic value of exercise QTc in addition to ST depression. Maximal exercise-QTc Bazett (r=0.163, p=0.01), Framingham (r=0.239, p=0.001), and Fri-dericia (r=0.206, p=0.001) equations were weakly positively correlated with Gensini scoring. Conclusion: The patients with CAD have longer QTc intervals at peak heart rates during exercise. This finding provides insufficient evid-ence to support routine incorporation of QTc at peak heart rates into exercise test interpretation.

Belching in Irritable Bowel Syndrome: An Impedance Study

( Tuba Obekli ),( Filiz Akyuz ),( Umit Akyuz ),( Serpil Arici ),( Raim Iliaz ),( Suut Gokturk ),( Sami Evirgen ),( Bilger Cavus ),( Cetin Karaca ),( Kadir Demir ),( Fatih Besisik ),( Sabahattin Kaymak 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2017 Journal of Neurogastroenterology and Motility (JNM Vol.23 No.3

Background/Aims There are limited data about the relation between belching and irritable bowel syndrome (IBS). We aim to evaluate belching in patients with IBS. Methods Twenty-five patients with IBS and 12 healthy volunteers were enrolled in the study. IBS was diagnosed in accordance with the Rome III criteria. All patients were questioned about the presence of symptoms for belching, gastroesophageal reflux disease, and dyspepsia. Esophageal manometry and 24-hour pH-impedance were performed in all patients and healthy volunteers. Each of the patients with IBS underwent gastroscopy and colonoscopy. Results Demographic features were similar in both groups (P > 0.05). The belching rate was 32% in patients with IBS. The mean DeMeester score was significantly higher in IBS patients (13.80 ± 14.40 vs 6.04 ± 5.60, P = 0.027) and 24% of patients had pathologic acid reflux (DeMeester score > 14). Gastroscopy was normal in all patients. Symptom association probability positivity was detected in 24% of patients in the impedance study. The rate of weak acid reflux was also significantly higher in patients with IBS (97.00 ± 56.20 vs 58.20 ± 29.30, P = 0.025). The number of supine gas reflux (7.50 ± 6.40 vs 2.42 ± 2.80, P = 0.001) and supragastric belches was significantly higher in patients with IBS (51.20 ± 41.20 vs 25.08 ± 15.20, P = 0.035). Although the number of gastric belching was higher in controls, the difference did not reach statistical significance (12.10 ± 17.60 vs 4.90 ± 3.80, P = 0.575). We did not find any correlation between belching and any symptoms of IBS. Conclusions Belching is frequent in patients with IBS. Non-erosive reflux disease is frequent in IBS, which may be related to supragastric belching. (J Neurogastroenterol Motil 2017;23:409-414)

Levoatrial Cardinal Vein: Occluder Embolization and Complication Management

Ilker Mercan,Muhammet Akyuz,Baris Guven,Onur Isik 대한흉부외과학회 2021 Journal of Chest Surgery (J Chest Surg) Vol.54 No.3

In rare cases, levoatrial cardinal vein may occur as an isolated condition without additional congenital anomalies. Depending on the direction and flow of the shunt, this pathology may produce symptoms; alternatively, it may be asymptomatic, as in the case presented in this study. In asymptomatic cases, complications, such as paradoxical embolism and brain abscess, can arise later. In the 11-year-old patient whose case is presented here, the levoatrial cardinal vein was asymptomatic and incidentally detected. The percutaneous closure method was applied first. However, by 16 hours after the procedure, the occluder device had embolized to the iliac artery. Emergency surgery was performed; first, the oc- cluder device was removed, and levoatrial cardinal vein ligation was then performed via a mini-thoracotomy. The symptoms, diagnosis, and treatment modalities of isolated levoatri- al cardinal vein are discussed in the context of this case described herein.

Incorporation of sporopollenin enhances acid–base durability, hydrophobicity, and mechanical, antifungal and antioxidant properties of chitosan films

Murat Kaya,Lalehan Akyuz,Idris Sargin,Muhammad Mujtaba,Asier M. Salaberria,Jalel Labidi,Yavuz S. Cakmak,Behlul Koc,Talat Baran,Talip Ceter 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.47 No.-

Sporopollenin-chitosan blendfilms were produced for thefirst time. Sporopollenin is a robust structuralcomponent of plant pollens exhibiting excellent features such as nontoxicity, biodegradability,biocompatibility, high thermal stability, durability to strong acid and base solutions and homogeneityin size. To benefit from these advantages, sporopollenin samples obtained from Betula pendula (silverbirch) were incorporated into chitosanfilm at different concentration; 10, 20 and 40 mg in 100 mLchitosan gel (1%). Stereo microscopy, FT-IR and TG/DTG analyses showed that sporopollenin wassuccessfully incorporated into the chitosan matrix. Incorporation of sporopollenin in gradually increasingamount into chitosanfilms was found advantageous in (1) enhancement in chemical durability of thefilms, (2) increment of hydrophobicity, (3) boosting the mechanical properties, (4) improvement ofantifungal and (5) antioxidant activities. This study revealed that sporopollenin can be suggested as aneffective blend material for biodegradable edible chitosanfilm production.

Does Cholecystectomy Increase the Esophageal Alkaline Reflux? Evaluation by Impedance-pH Technique

( Ahmet Uyanikoglu ),( Filiz Akyuz ),( Fatih Ermis ),( Serpil Arici ),( Gurhan Bas ),( Mustafa Cakirca ),( Bulent Baran ),( Zeynel Mungan ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2012 Journal of Neurogastroenterology and Motility (JNM Vol.18 No.2

Background/Aims The aim of this study is to investigate the reflux patterns in patients with galbladder stone and the change of reflux patterns after cholecystectomy in such patients. Methods Fourteen patients with cholecystolithiasis and a control group including 10 healthy control subjects were enrolled in this prospective study. Demographical findings, reflux symptom score scale and 24-hour impedance pH values of the 14 cholecystolithiasis cases and the control group were evaluated. The impedance pH study was repeated 3 months after cholecystectomy. Results Age, gender, and BMI were not different between the two groups. Total and supine weakly alkaline reflux time (%) (1.0 vs 22.5, P = 0.028; 201.85 vs 9.65, P = 0.012), the longest episodes of total, upright and supine weakly alkaline reflux mediums (11 vs 2, P = 0.025; 8.5 vs 1.0, P = 0.035; 3 vs 0, P = 0.027), total and supine weakly alkaline reflux time in minutes (287.35 vs 75.10, P = 0.022; 62.5 vs 1.4, P = 0.017), the number of alkaline reflux episodes (162.5 vs 72.5, P = 0.022) were decreased with statistical significance. No statistically significant difference was found in the comparison of symptoms between the subjects in the control group and the patients with cholecystolithiasis, in preoperative, postoperative and postcholecystectomy status. Conclusions Significant reflux symptoms did not occur after cholecystectomy. Post cholecystectomy weakly alkaline reflux was decreased, but it was determined that acid reflux increased after cholecystectomy by impedance pH-metry in the study group.

Extraction of high thermally stable and nanofibrous chitin from Cicada (Cicadoidea)

Abbas Mol,Murat Kaya,Muhammad Mujtaba,Bahar AKYUZ 한국곤충학회 2018 Entomological Research Vol.48 No.6

Due to the increasing interest in natural biopolymers including chitin, the exploitation of economic and easily accessible chitin sources with good physicochemical properties is nowadays required. In view of this fact, in the current study chitin was extracted and physicochemically characterized from six Cicadas (Hemiptera: Homoptera: Cicadoidea) species collected from Mediterranean region of Turkey (2014–15). Chitin was extracted using a classic extraction method that includes acid and base treatment. TGA results revealed a remarkable increase (410–412°C) for all the six Cicada species compared to other chitin samples extracted from various sources. For all of the six selected species the chitin contents on the dry basis were determined as 6.7% for Cicadatra atra, 5.51% for C. hyalina, 8.84% for C. platyptera, 4.97% for Cicada lodosi, 6.49% for C. mordoganensis, and 5.88% for Cicadetta tibialis. The surface morphology of chitin isolates from Cicada species was observed to consist of nanofibers and nanopores.