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LIST EDGE AND LIST TOTAL COLORINGS OF PLANAR GRAPHS WITHOUT 6-CYCLES WITH CHORD
Dong, Aijun,Liu, Guizhen,Li, Guojun Korean Mathematical Society 2012 대한수학회보 Vol.49 No.2
Giving a planar graph G, let $x^'_l(G)$ and $x^{''}_l(G)$ denote the list edge chromatic number and list total chromatic number of G respectively. It is proved that if a planar graph G without 6-cycles with chord, then $x^'_l(G){\leq}{\Delta}(G)+1$ and $x^{''}_l(G){\leq}{\Delta}(G)+2$ where ${\Delta}(G){\geq}6$.
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LIST EDGE AND LIST TOTAL COLORINGS OF PLANAR GRAPHS WITHOUT 6-CYCLES WITH CHORD
Aijun Dong,Guizhen Liu,Guojun Li 대한수학회 2012 대한수학회보 Vol.49 No.2
Giving a planar graph G, let $x^'_l(G)$ and $x^{''}_l(G)$ denote the list edge chromatic number and list total chromatic number of G respectively. It is proved that if a planar graph G without 6-cycles with chord, then $x^'_l(G){\leq}{\Delta}(G)+1$ and $x^{''}_l(G){\leq}{\Delta}(G)+2$ where ${\Delta}(G){\geq}6$.
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Huihui Cao,Yanhua Yan,Lei Wang,Lixue Dong,Xueliang Pang,Sining Tang,Aijun Li,Aili Xiang,Litian Zhang,Baiqin Zheng 한국축산식품학회 2021 한국축산식품학회지 Vol.41 No.3
Raw milk is a nature media of microbiota that access milk from various sources, which constitutes a challenge in dairy production. This study characterizes the relationship between the raw milk quality and the bacteria diversity at different sampling sites in dairy farms, aiming to provide a strong scientific basis for good hygienic practices and optimized procedure in milk production. High-throughput sequencing of 16S rRNA V3-V4 region was used to analyze the components, abundance and diversity of 48 bacterial population sampled from 8 different sites in dairy farm: pre-sterilized cow’s teats (C1), post-sterilized cow’s teats (C2), milking cluster (E), milk in storage tank (M1), transport vehicle (M2), storage equipment (E2), cow’s dung samples (F) and drinking water (W). Firmicutes account for predominantly 32.36% (C1), 44.62% (C2), 44.71% (E), 41.10% (M1), 45.08% (M2), 53.38% (F) of all annotated phyla. Proteobacteria accounts for 81.79% in W group and Actinobacteria 56.43% in E2 group. At the genus level, Acinetobacter was the most abundant genus that causes bovine mastitis, Acinetobacter and Arthrobacter were dominant in C1, C2, and E groups, Kocuria in E2 group and Arcobacter in W group. E, C1, and C2 group have very similar bacterial composition, and M1 and M2 demonstrated similar composition, indicating that the milking cluster was polluted by the environment or contact with cow udders. Bacterial population composition in different sampling sites identified by NGS reveals a correlation between the bacteria communities of raw milk production chain and the quality of raw milk.
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Bionic natural small molecule co-assemblies towards targeted and synergistic Chemo/PDT/CDT
Shiyao Fu,Mingao Wang,Bin Li,Xu Li,Jianjun Cheng,Haitian Zhao,Hua Zhang,Aijun Dong,Weihong Lu,Xin Yang 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00
Background Multi-component nano-delivery systems based on chemotherapy (chemo)- photodynamic therapy (PDT)- chemodynamic therapy (CDT) have gained increased attention as a promising strategy to improve clinical outcomes in cancer treatment. However, there remains a challenge in developing biodegradable, biocompatible, less toxic, yet highly efficient multicomponent nanobased drug delivery systems (DDS). Here, our study presents the screening and development of a novel DDS based on co-assemblies natural small molecule (NSMs). These molecules (oleanolic acid, and betulinic acid) are combined with photosensitizers Chlorine6 (Ce6) and Cu2+ that are encapsulated by tumor cell membranes. This nanocarrier encapsulated in tumor cell membranes achieved good tumor targeting and a significant improvement in tumor accumulation. Methods A reprecipitation method was used to prepare the co-assembled nanocarrier, followed by the introduction of Cu2 + into the DDS (OABACe6 NPs). Then, by wrapping the surface of NPs with the cell membranes of 4T1 which is a kind of mouse breast cancer cells (CM@OABACe6/Cu NPs). and analysis of its structure and size distribution with UV– Vis, XPS, FT-IR, SEM, TEM, and DLS. The synergistic effects of in vitro chemotherapy, CDT and PDT and targeting were also validated by cellular and animal studies. Results It was shown that CM@OABACe6/Cu NPs achieved good tumor targeting and a significant improvement in tumor accumulation. In the composite nano-assembly, the NSMs work together with the Ce6 to provide effective and safe chemo and PDT. Moreover, the effect of reduced PDT due to the depletion of reactive oxygen species (ROS) by excess glutathione (GSH) in the tumor can be counteracted when Cu2 + is introduced. More importantly, it also confers CDT through a Fenton-like catalytic reaction with H2O overexpressed at the tumor site. Conclusions By constructing CM@OABACe6/Cu NPs with homologous targeting, we create a triple synergistic platform for cancer therapy using PDT, chemo, and CDT. We propose here a novel combinatorial strategy for designing more naturally co-assembled small molecules, especially for the development of multifunctional synergistic therapies that utilize NSMs.
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