Real-time modeling prediction for excavation behavior

Li-FengNi,Ai-QunLi,Fu-YiLiu,HonoreYin,J.R.Wu 국제구조공학회 2003 Structural Engineering and Mechanics, An Int'l Jou Vol.16 No.6

A nondestructive method for controlling wind loads and wind-induced responses of wooden pagoda

Yuhang LI,Yang Deng,Ai-Qun Li 한국풍공학회 2022 Wind and Structures, An International Journal (WAS Vol.34 No.6

High-rise wooden pagodas generate large displacement responses under wind action. It is necessary and wise to reduce the wind loads and wind-induced responses on the architectural heritage using artificial plants, which do not damage ancient architecture and increase greenery. This study calculates and analyzes the wind loads and wind-induced responses on the Yingxian Wooden Pagoda, in China, using artificial plants via the finite element analysis (FEA). A three-dimensional windloading field was simulated using a wind tunnel test. Wind loads and wind-induced responses, including the displacement and acceleration of the pagoda with and without artificial plants, were analyzed. In addition, three types of tree arrangements were discussed and analyzed using the score method. The results revealed that artificial plants can effectively control wind loads and wind-induced displacements, but the wind-induced accelerations are enlarged to some extent during the process. The height of the tree significantly affected the shelter effects of the structure. The distance of trees from the pagoda and arrangement width of the tree had less influence on shelter effects. This study extends the understanding of the nondestructive method based on artificial plants, for controlling the wind base loads and structural responses of wooden pagodas and preserving architectural heritage via FEA.

Real-time modeling prediction for excavation behavior

Ni, Li-Feng,Li, Ai-Qun,Liu, Fu-Yi,Yin, Honore,Wu, J.R. Techno-Press 2003 Structural Engineering and Mechanics, An Int'l Jou Vol.16 No.6

Two real-time modeling prediction (RMP) schemes are presented in this paper for analyzing the behavior of deep excavations during construction. The first RMP scheme is developed from the traditional AR(p) model. The second is based on the simplified Elman-style recurrent neural networks. An on-line learning algorithm is introduced to describe the dynamic behavior of deep excavations. As a case study, in-situ measurements of an excavation were recorded and the measured data were used to verify the reliability of the two schemes. They proved to be both effective and convenient for predicting the behavior of deep excavations during construction. It is shown through the case study that the RMP scheme based on the neural network is more accurate than that based on the traditional AR(p) model.

A simple rat model of in situ reversible obstructive jaundice in situ reversible obstructive jaundice model

Xin Huang,Chong-Hui Li,Ai-Qun Zhang,Zhe Kong,Wan-Qing Gu,Jia-Hong Dong 대한외과학회 2017 Annals of Surgical Treatment and Research(ASRT) Vol.92 No.6

Purpose: To develop a simple and reliable rat model of in situ reversible obstructive jaundice with low morbidity and mortality rates. Methods: Rats were divided into 4 groups with 8 rats each: the sham-operated (SH) group only underwent laparotomy, the control internal drainage (ID-C) group underwent choledochoduodenostomy, the new internal drainage (ID-N) group and the long-term internal drainage (ID-L) group underwent choledochocholedochostomy. Common bile duct ligation was performed in all the drainage groups 7 days before reversal procedures. All rats were sacrificed for samples 7 days after the last operation except rats of the ID-L group that survived 28 days before sacrifice. Body weight, liver function, histopathological changes, morbidity and mortality were assessed. Results: One rat died and 2 rats had complications with tube blockage in the ID-C group. No death or complications occurred in the ID-N and ID-L groups. The drainage tube remained patent in the long-term observation ID-L group. Body weight showed no significant difference between the ID-C and ID-N groups after 7 days drainage. Liver function was not fully recovered in the ID-C and ID-N groups after 7 days drainage, but statistical differences were only observed in the ID-C group compared with the SH and ID-L groups. Periportal inflammation and bile duct proliferation showed severer in the ID-C group than in the ID-N group. Conclusion: The present study provided an efficient, simple, and reliable rat model that is especially suitable for long-term or consecutive studies of reversible obstructive jaundice.

Elevated Serum Ferritin Levels in Patients with Hematologic Malignancies

Zhang, Xue-Zhong,Su, Ai-Ling,Hu, Ming-Qiu,Zhang, Xiu-Qun,Xu, Yan-Li Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15

Purpose: To retrospectively analyze variability and clinical significance of serum ferritin levels in Chinese patients with hematologic malignancies. Materials and Methods: Serum ferritin were measured by radioimmunoassay, using a kit produced by the Beijing Institute of Atomic Energy. Patients with hematologic malignancies, and treated in the Department of Hematology in Nanjing First Hospital and fulfilled study criteria were recruited. Results: Of 473 patients with hematologic malignancies, 262 patients were diagnosed with acute leukemia, 131 with lymphoma and 80 with multiple myeloma. Serum ferritin levels of newly diagnosed and recurrent patients were significantly higher than those entering complete remission stage or in the control group (p<0.001). Conclusions: Serum ferritin lever in patients with hematologic malignancies at early stage and recurrent stage are significantly increased, so that detection and surveillance of changes of serum ferritin could be helpful in assessing conditions and prognosis of this patient cohort.

The seismic responses of girder bridges with novel sliding lead rubber bearings

Wu, Yi-feng,Li, Ai-qun,Wang, Hao Techno-Press 2021 Structural monitoring and maintenance Vol.8 No.3

Based on the commonly used lead rubber bearing (LRB) and sliding rubber bearing (SRB), a novel sliding lead rubber bearing (SLRB) is introduced. The mechanical properties of the three types of bearings were investigated by experiment. After that, a simply supported girder bridge with a 1/4 scale ratio was designed and fabricated, and the dynamic characteristics and seismic response of the bridge equipped with the above three types of bearings were studied. Results show that the girder's acceleration response has been effectively reduced by setting bearings only for relatively high earthquake intensity. Compared with LRB and SRB, SLRB works with more compositive seismic isolation effect. The "slide" action of the telflon-stainless-steel interface in SLRB can significantly reduce the acceleration response of girder, while the relative displacement between the pier and girder for this novel bearing is not increased due to the occurrence of collision in the bearing.

Expression of Ang-2/Tie-2 and PI3K/AKT in Colorectal Cancer

Zhang, Ji-Hong,Wang, Li-Hua,Li, Xiang-Jun,Wang, Ai-Ping,Reng, Li-Qun,Xia, Feng-Guo,Yang, Zhi-Ping,Jiang, Jing,Wang, Xiao-Dan,Wen, Chun-Yang Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

Purpose: To study the expression of angiogenin-2 (Ang-2) and its receptor Tie-2 in colorectal cancer and discuss the possible mechanisms behind this process. Materials and Methods: Using the streptavidin-peroxidase (SP) immunohistochemical method, paraffin sections from 100 colorectal cancer samples and 10 samples from tumor-adjacent normal tissue (> 2 cm from the edge of the gross tumor) were tested for protein expression of Ang-2, Tie-2, PI3K, and AKT. Reverse transcription-polymerase chain reaction and Western blots were further used to measure expression of the 4 genes and proteins in 20 freshly-resected colorectal cancer samples and tumor-adjacent normal tissues. Results: In colorectal cancer tissues, the expression of the Ang-2, Tie-2, PI3K, and AKT genes and their proteins was significantly higher than in tumor-adjacent normal tissues. Protein expression in poorly-differentiated adenocarcinoma was higher than that in well and moderately differentiated adenocarcinoma. According to Duke's classification, the protein expression in Stages C and D was significantly higher than that in Stages A and B. In the group with lymphatic metastasis, the protein expression was higher than that without lymphatic metastasis. Conclusions: In colorectal cancer, the expression of the Ang-2, Tie-2, PI3K, and AKT genes and their proteins is markedly higher than those in tumor-adjacent normal tissues. No correlation was observed between protein expression and gender, location, or histologic type. Correlations did exist between protein expression and differentiation level, stage of Duke's classification, and lymphatic metastasis; in colorectal cancer tissues with lower differentiation levels, higher stages of Duke's classification, and lymphatic metastasis, the expression of all 4 proteins was higher. The study of their expression patterns and relationships with aggression and metastasis will provide a valuable experimental foundation for assessing prognosis and targeted therapy of colorectal cancer.

Proposal of a Pretreatment Nomogram for Predicting Local Recurrence after Intensity-Modulated Radiation Therapy in T4 Nasopharyngeal Carcinoma: A Retrospective Review of 415 Chinese Patients

Lu-Lu Zhang,Yi-Yang Li,Jiang Hu,Guan-Qun Zhou,Lei Chen,Wen-Fei Li,Ai-Hua Lin,Jun Ma,Zhen-Yu Qi,Ying Sun 대한암학회 2018 Cancer Research and Treatment Vol.50 No.4

Purpose Local relapse-free survival (LRFS) differs widely among patients with T4 category nasopharyngeal carcinoma (NPC). We aimed to build a nomogram incorporating clinicopathological information to predict LRFS in T4 NPC after definitive intensity-modulated radiation therapy (IMRT). Materials and Methods Retrospective study of 415 Chinese patients with non-metastatic T4 NPC treated with definitive IMRT with or without chemotherapy at our cancer center between October 2009 and September 2013. The nomogram for LRFS at 3 and 5 years was generated based on multivariate Cox proportional hazards regression, and validated using bootstrap resampling, assessing discriminative performance using the concordance index (C-index) and determining calibration ability via calibration curves. Results Five-year LRFS was 88.8%. We identified and incorporated four independent prognostic factors for LRFS: ethmoid sinus invasion, primary gross tumor volume, age, and pretreatment body mass index. The C-index of the nomogram for local recurrence was 0.732 (95% confidence interval, 0.726 to 0.738), indicating excellent predictive accuracy. The calibration curve revealed excellent agreement between nomogram-predicted and observed LRFS probabilities. Risk subgroups based on total point score cutoff values enabled effective discrimination of LRFS. Conclusion This pretreatment nomogram enables clinicians to accurately predict LRFS in T4 NPC after definitive IMRT, and could help to facilitate personalized patient counselling and treatment strategies.

A kind of NiTi-wire shape memory alloy damper to simultaneously damp tension, compression and torsion

Yu-Lin Han,Hai-Yang Yin,Er-Tian Xiao,Zhi-Lin Sun,Ai-Qun Li 국제구조공학회 2006 Structural Engineering and Mechanics, An Int'l Jou Vol.22 No.2

The compression-shear properties of small-size seismic isolation rubber bearings for bridges

Wu, Yi-feng,Wang, Hao,Sha, Ben,Zhang, Rui-jun,Li, Ai-qun Techno-Press 2018 Structural monitoring and maintenance Vol.5 No.1

Taking three types of bridge bearings with diameter being 100 mm as examples, the theoretical analysis, the experimental research as well as the numerical simulation of these bearings is conducted. Since the normal compression and shear machines cannot be applied to the small-size bearings, an improved equipment to test the properties of these bearings is proposed and fabricated. Besides, the simulation of the bearings is conducted based on the explicit finite element software ANSYS/LS-DYNA, and some parameters of the bearings are modified in the finite element model to reduce the computation cost effectively. Results show that all the research methods are capable of revealing the fundamental properties of the small-size bearings, and a combined use of these methods can better catch both the integral properties and the inner detailed mechanical behaviors of the bearings.