Effect of Restricted Suckling or Temporal Weaning on Some Physiological and Behavioural Stress Parameters in Zebu Cattle (Bos indicus)

Acevedo, N.,Hernandez, C.,Orihuela, A.,Lidfors, L.M.,Berg, C. Asian Australasian Association of Animal Productio 2005 Animal Bioscience Vol.18 No.8

This study investigated the effects of restricted suckling (RS) on some physiological and behavioural stress parameters compared to temporal weaning (TW). Twenty Brahman (Bos indicus) cow-calf pairs were assigned to one of two groups: Calves in the RS group were limited to suckle their dams once daily for 30 min during days 30 to 33, while calves in the TW group were removed from their dams during days 59 to 62 postpartum. Heart and respiratory rates, serum cortisol concentration and body temperature were registered in cows and calves. In addition, the number of steps was also registered in calves. All parameters were recorded 24, 48 and 72 h after the beginning of the two treatments, respectively. In TW calves, higher (p<0.05) cortisol concentration and number of steps were recorded in the 1st samples and 1$^{st}$ and 2$^{nd}$ observations, respectively. No difference was found in body temperature between treatments. However, respiration and heart rates differed in the 1$^{st}$ and 2$^{nd}$ observations, respectively. In general, a significant decrease (p<0.05) in these three parameters was observed over time. In cows, no differences were found in cortisol concentration or body temperature between treatments or with time. Heart and respiratory rates were lower (p<0.05) in the TW treatment only 24 h after beginning of treatment. It was concluded that (a) RS resulted in less behavioural and physiological indices of distress compared to TW in calves, although in general, differences were found only in some variables, mainly during the 1$^{st}$ day following start of the treatment, and there in a chance of age effects. (b) Cows were less affected than their young, regardless of the treatment applied.

OPENNESS OF ANOSOV FAMILIES

Acevedo, Jeovanny de Jesus Muentes Korean Mathematical Society 2018 대한수학회지 Vol.55 No.3

Anosov families were introduced by A. Fisher and P. Arnoux motivated by generalizing the notion of Anosov diffeomorphism defined on a compact Riemannian manifold. Roughly, an Anosov family is a two-sided sequence of diffeomorphisms (or non-stationary dynamical system) with similar behavior to an Anosov diffeomorphisms. We show that the set consisting of Anosov families is an open subset of the set consisting of two-sided sequences of diffeomorphisms, which is equipped with the strong topology (or Whitney topology).

Breast Cancer at Extreme Ages - a Comparative Analysis in Chile

Acevedo, Francisco,Camus, Mauricio,Sanchez, Cesar Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.4

Background: Young onset breast cancer (BC) has a worse outcome as compared to in the elderly. However, some studies have shown that BC in the elderly, despite indolent features, does also cause increase in mortality. In an attempt to compare clinic-pathological characteristics, BC subtypes and survival in patients with BC presenting at extremes of age, we performed a retrospective study. Materials and Methods: Patients were either ${\leq}40$ or ${\geq}70$ years old. Subtypes were defined using immunohistochemistry and histological grade. Chi-Square test was used for evaluation of categorical variables, and Kaplan-meier and log-rank for disease-specific survival (DSS) and disease free survival (DFS). Results: We analyzed 256 patients ${\leq}40$ and 366 patients ${\geq}70$. Younger patients presented with more aggressive disease, with less luminal A but more luminal B and triple negative (TN) subtype. With a median follow-up of 57.5 months, DFS at 5 years in younger patients was 72.3% vs 84.6% in the elderly (p=0.007). Luminal A and B disease presented with worse DFS in younger patients. The opposite was seen in the TN subgroup. Although we found no significant differences in DSS, older patients with TN tumors died of BC more frequently. This group also received less chemotherapy. Conclusions: Young patients present with more aggressive disease, this translating into worse DFS. However, elderly patients with TN disease represent a particular subpopulation with worse DFS and DSS, suggesting that chemotherapy should not be withheld only because of age.

El ge´nero periodi´stico en el espan~ol de los Estados Unidos

Acevedo, Rebeca,Pak, Chin-Sook 서울大學校 스페인中南美硏究所 2003 이베로아메리카硏究 Vol.14 No.-

The study of cross-cultural rhetorical patterns in written texts has been an area of growing interest during the last three decades. Contrastive Rhetoric, the hypothesis that different cultures can have different ways of organizing ideas which manifest themselves in different rhetorical systems, has become and influential research area, providing useful insights to understanding the forms, contents, and contexts that shape different types of texts across a variety of cultures. The present study examines a number of rhetorical and stylistic features in the editorials of La Opinio´n, the Spanish language newspaper with the largest circulation size in the United States. By comparing the findings with previous Contrastive Rhetoric studies on the genre of editorials from other prestigious newspapers such as The New York Times, El Pai´s (Madrid), and El Universal (Mexico City), the article highlights unique discourse features found in the Spanish of Los Angeles. The results of this study can be used to not only improve critical reading of these texts but also recognize the pluricentrality of cultures sharing the same Spanish language, in this case, Spain, Mexico and the United States.

Pregelatinized starches enriched in slowly digestible and resistant fractions

Agama-Acevedo, Edith,Bello-Perez, Luis A.,Lim, Jongbin,Lee, Byung-Hoo,Hamaker, Bruce R. Elsevier 2018 LWT- Food science and technology Vol.97 No.-

<P><B>Abstract</B></P> <P>Consumption of slowly digestible and resistant starches (SDS and RS) is known to modulate postprandial glucose levels and attain extended glucose release. In this study, pregelatinized high-amylose maize starches (50 and 70 g amylose 100 g<SUP>−1</SUP> starch) were subjected to hydrothermal treatments [40 g water 100 g<SUP>−1</SUP>, heat-moisture treated (HMT) at 100 °C and low temperature-moisture treated (LMT) at 4 °C] to increase total amount of SDS and RS. Hydrothermal treatment of pregelatinized high-amylose starches produced higher amounts of SDS (27.0 and 26.4% for HMT and LMT amylomaize V, and 21.5 and 21.6% for HMT and LMT amylomaize VII) and RS (36.2 and 31.5 g/100 g, and 47.5 and 37.5 g/100 g, respectively), than pregelatinized normal or waxy starches (SDS - 2.3 and 3.2 g/100 g, and 13.7 and 15.8 g/100 g, respectively; and RS 10.2 and 7.8 g/100 g, and 12.4 and 11.0 g/100 g, respectively). Granule morphology was retained in pregelatinized high-amylose starches, apparently due to their restricted swelling. Starch debranching profiles showed a minor increase in DP 25-36 in SDS and RS, suggesting that higher intermediate fractions of the high-amylose starches may create an overall material effect resulting in slower digestion of hydrothermal treated starches. High SDS and RS in pregelatinized starches could be applied in cold-formed food products.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Treated pregel high-amylose starches have slowly digestible and resistant fractions. </LI> <LI> Starch fine structure contributes to slowly digestible starch formation. </LI> <LI> Treated pregelatinized starches could have use in cold-formed processed foods. </LI> </UL> </P>

House Dust Mite Allergy Under Changing Environments

Nathalie Acevedo,Josefina Zakzuk,Luis Caraballo 대한천식알레르기학회 2019 Allergy, Asthma & Immunology Research Vol.11 No.4

Environmental variations induced by industrialization and climate change partially explain the increase in prevalence and severity of allergic disease. One possible mechanism is the increase in allergen production leading to more exposure and sensitization in susceptible individuals. House dust mites (HDMs) are important sources of allergens inducing asthma and rhinitis, and experimentally they have been demonstrated to be very sensitive to microenvironment modifications; therefore, global or regional changes in temperature, humidity, air pollution or other environmental conditions could modify natural HDM growth, survival and allergen production. There is evidence that sensitization to HDMs has increased in some regions of the world, especially in the subtropical and tropical areas; however, the relationship of this increase with environmental changes is not so clear as has reported for pollen allergens. In this review, we address this point and explore the effects of current and predicted environmental changes on HDM growth, survival and allergen production, which could lead to immunoglobulin E (IgE) sensitization and allergic disease prevalence. We also assess the role of adjuvants of IgE responses, such as air pollution and helminth infections, and discuss the genetic and epigenetic aspects that could influence the adaptive process of humans to drastic and relatively recent environmental changes we are experiencing.

Measuring the Impact of Human Capital on the Economic Growth of South Korea

Sebastian Acevedo 한국경제연구학회 2008 Korea and the World Economy Vol.9 No.1

The aim of this paper is to measure total factor productivity (TFP) growth in Korea without taking into account quality differences in the labor factor. Therefore, assuming that Lucas (1988) theory of endogenous growth is correct, the standard TFP measure will be overestimated and will include the contribution of human capital to economic growth. Hence, regressing the TFP growth against a proxy of human capital (average years of schooling) will estimate the impact of education on the economic growth of Korea. The main result of the study shows that between 1980 and 2004 the Korean economy grew at an annual rate of 6.7% and human capital accumulation accounted for 1.3 percentage points of that rate.

Openness of Anosov families

Jeovanny de Jesus Muentes Acevedo 대한수학회 2018 대한수학회지 Vol.55 No.3

Anosov families were introduced by A. Fisher and P. Arnoux motivated by generalizing the notion of Anosov diffeomorphism defined on a compact Riemannian manifold. Roughly, an Anosov family is a two-sided sequence of diffeomorphisms (or non-stationary dynamical system) with similar behavior to an Anosov diffeomorphisms. We show that the set consisting of Anosov families is an open subset of the set consisting of two-sided sequences of diffeomorphisms, which is equipped with the strong topology (or Whitney topology).

Optimization of silver nanoparticle synthesis by chemical reduction and evaluation of its antimicrobial and toxic activity

Catalina Quintero-Quiroz,Natalia Acevedo,Jenniffer Zapata-Giraldo,Luz E. Botero,Julián Quintero,Diana Zárate-Triviño,Jorge Saldarriaga,Vera Z. Pérez 한국생체재료학회 2020 생체재료학회지 Vol.24 No.1

Background: Chemical reduction has become an accessible and useful alternative to obtain silver nanoparticles (AgNPs). However, its toxicity capacity depends on multiple variables that generate differences in the ability to inhibit the growth of microorganisms. Thus, optimazing parameters for the synthesis of AgNPs can increase its antimicrobial capacity by improving its physical-chemical properties. Methods: In this study a Face Centered Central Composite Design (FCCCD) was carried out with four parameters: AgNO3 concentration, sodium citrate (TSC) concentration, NaBH4 concentration and the pH of the reaction with the objective of inhibit the growth of microorganisms. The response variables were the average size of AgNPs, the peak with the greatest intensity in the size distribution, the polydispersity of the nanoparticle size and the yield of the process. AgNPs obtained from the optimization were characterized physically and chemically. The antimicrobial activity of optimized AgNPs was evaluated against Staphylococcus aureus, Escherichia coli, Escherichia coli AmpC resistant, and Candida albicans and compared with AgNPs before optimization. In addition, the cytotoxicity of the optimized AgNPs was evaluated by the colorimetric assay MTT (3- (4,5- Dimethylthiazol- 2- yl)- 2, 5 - Diphenyltetrazolium Bromide). Results: It was found that the four factors studied were significant for the response variables, and a significant model (p <0.05) was obtained for each variable. The optimal conditions were 8 for pH and 0.01 M, 0.0 6M, 0.01 M for the concentration of TSC, AgNO3, and NaBH4, respectively. Optimized AgNPs spherical and hemispherical were obtained, and 67.66% of it had a diameter less than 10.30 nm. A minimum bactericidal concentration (MBC) and minimum fungicidal Concentration (MFC) of optimized AgNPs was found against Staphylococcus aureus, Escherichia coli, Escherichia coli AmpC resistant, and Candida albicans at 19.89, 9.94, 9.94, 2.08 μg/mL, respectively. Furthermore, the lethal concentration 50 (LC50) of optimized AgNPs was found on 19.11 μg/mL and 19.60 μg/mL to Vero and NiH3T3 cells, respectively. Conclusions: It was found that the factors studied were significant for the variable responses and the optimization process used was effective to improve the antimicrobial activity of the AgNPs.

Correlation between Ki67 and Histological Grade in Breast Cancer Patients Treated with Preoperative Chemotherapy

Petric, Militza,Martinez, Santiago,Acevedo, Francisco,Oddo, David,Artigas, Rocio,Camus, Mauricio,Sanchez, Cesar Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23

Background and Aim: Breast cancer (BC) is a heterogeneous disease and cell proliferation markers may help to identify subtypes of clinical interest. We here analyzed the correlation between cell proliferation determined by Ki67 and HG in BC patients undergoing preoperative chemotherapy (PCT). Materials and Methods: We obtained clinical/pathological data from patients with invasive BC treated at our institution from 1999 until 2012. Expression of estrogen receptor (ER), progesterone receptor (PR), epidermal growth factor receptor type 2 (HER2) and Ki67 were determined by immuno-histochemistry (IHC). Clinicopathological subtypes were defined as: Luminal A, ER and/or PR positive, HER2 negative, HG 1 or 2; Luminal B, ER and/or PR positive, HER2 negative or positive and/or HG 3; triple negative (TN), ER, PR and HER2 negative independent of HG; HER2 positive, ER, PR negative and HER2 positive, independent of HG. By using Ki67, a value of 14% separated Luminal A and B tumors, independently of the histological grade. We analyzed correlations between Ki67 and HG, to define BC subtypes and their predictive value for response to PCT. Results: 1,560 BC patients were treated in the period, 147 receiving PCT (9.5%). Some 57 had sufficient clinicopathological information to be included in the study. Median age was 52 years (26-72), with 87.7% invasive ductal carcinomas (n=50). We performed IHC for Ki67 in 40 core biopsies and 50 surgical biopsies, 37 paired samples with Ki67 before and after chemotherapy being available. There was no significant correlation between Ki67 and HG (p=0.237), both categorizing patients into different subtypes. In most cases Ki67 decreased after PCT (65.8%). Only 3 patients had pathologic complete response (cPR). Conclusions: In our experience we did not find associations between Ki67 and HG. Determination of clinicopathological luminal subtypes differs by using Ki67 or HG.