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포스터 전시 : 담도,췌장 ; 장기간 혈액투석을 시행받는 만성 신부전 환자에서 발생한 급성 괴사성 췌장염에 동반된 장 경색 1예
한요셉 ( Yo Seb Han ),동석호 ( Seok Ho Dong ),김한숙 ( Han Suk Kim ),이동근 ( Dong Keun Lee ),김효종 ( Hyo Jong Kim ),김병호 ( Byung Ho Kim ),장영운 ( Young Woon Chang ),이정일 ( Joung Il Lee ),장린 ( Rin Chang ) 대한소화기학회 2002 대한소화기학회 춘계학술대회 Vol.2002 No.-
만성신부전환자에서 발생하는 급성췌장염은 만성신부전이 없는 환자에서와 달리 원인이 알코올, 담석, 약물에서도 기타의 원인들이 많은 것으로 보고되고 있다. 혈액투석을 시행받는 만성신부전환자에서 급성췌장염의 발생기전은 대부분 전신적인 동맥경화증의 진행으로 인한만성 허혈성 손상에 의한 것이며 그 밖에 이뇨제, 고중성지방혈증, 고칼슘혈증, 저혈압 등이 관여하는 것으로 알려져 있다. 만성신부전환자는 동맥경화성 혈관을 가지고 있고 혈액투석증에 종종 저혈압을 경험하곤
운동 이상형 기능성 소화불량증 환자에서 말레인산 돔페리돈과 염산 이토프리드의 효과 비교 연구
한요셉 ( Yo Seb Han ),장영운 ( Young Woon Chang ),장린 ( Rin Chang ) 대한소화기학회 2003 대한소화기학회지 Vol.41 No.4
Background/Aims: Domperidone and itopride are prokinetic drugs for the treatment of dysmotility-type functional dyspepsia. The aim of this study was to compare the efficacy and safety of domperidone and itopride in the treatment of dysmotility-type functional dyspepsia. Methods: One hundred and fifty-four patients with more than moderate symptoms of dysmotility-type functional dyspepsia were recruited in a prospective parallel comparison study. They were randomized and treated with either 10 mg of domperidone t.i.d. (76 patients, domperidine group) or 50 mg of itopride t.i.d. (78 patients, itopride group) for 14 days. The treatment efficacy measured by physicians global evaluation was percent of patients who showed excellent (=75% improvement in total symptom score from baseline) or good (=50% improvement in total symptom score) responses. Results: In both domperidone and itopride groups, dyspeptic symptoms of the patients improved significantly. Postprandial abdominal fullness and epigastric bloating sense were markedly decreased without significant difference in both groups. Epigastric lump sense was more improved in the domperidone group than in the itopride group. The treatment efficacy in domperidone group was 75% and 66.7% in itopride group. However, the difference was not significant. Additionally no serious adverse events were reported. Conclusions: Domperidone and itopride are similarly effective in the treatment of dysmotility-type functional dyspepsia. (Korean J Gastroenterol 2003;41:284-289)
한요셉(Yo Seb Han),김병호(Byung Ho Kim) 대한소화기학회 2001 대한소화기학회지 Vol.38 No.5
Despite the lack of evidence that screening for hepatocellular carcinoma (HCC) is of benefit in reducing mortality, it has widely accepted by gastroenterologist in the area where the prevalence of HCC is high. We reviewed the articles related to the epidemiology of HCC which had been reported in the 1990s in Korea. We also tried to select the patients in whom screening may be effective. Liver cirrhosis increases the risk of HCC about 6 folds. Among cirrhotics, HBV and HCV-related cirrhosis and alcoholic cirrhosis comprised more than 95% of patients with HCC in the 1990s in Korea. In chronic hepatitis B, the risk of HCC increases over the age of 30 in male and the age of 40 in female. In chronic hepatitis C, the risk of HCC is mainly limited to those who have established cirrhosis, but there is minimum risk under the age of 40 in both sex. Although ethanol is not considered as a carcinogen, cirrhotic change caused by chronic alcohol ingestion can be a risk of HCC. (Korean J Gastroenterol 2001;38:313-318)
대한간학회지 제6차 춘계학술대회 초록집 : 구연 ; 1990년대 간경변증의 원인, 합병증 및 사망원인 변화에 관한 고찰
한요셉 ( Han Yo Seb ),김병호 ( Kim Byeong Ho ),백일현 ( Baeg Il Hyeon ),이동근 ( Lee Dong Geun ),김경진 ( Kim Gyeong Jin ),동석호 ( Dong Seog Ho ),김효종 ( Kim Hyo Jong ),장영운 ( Jang Yeong Un ),이정일 ( Lee Jeong Il ),장린 ( Ja 대한간학회 2000 Clinical and Molecular Hepatology(대한간학회지) Vol.6 No.1(S)