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- 저자 : 오성욱 ( Sung Wook Ok ) (검색결과 2 건)
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담낭 결석이 동반되지 않은 담낭 용종의 악성화 관련 인자
이재승 ( Jae Seung Lee ),이규택 ( Kyu Taek Lee ),정재홍 ( Jae Hong Jung ),오성욱 ( Sung Wook Ok ),최성철 ( Sung Chul Choi ),이광혁 ( Kwang Hyuck Lee ),이종균 ( Jong Kyun Lee ),허진석 ( Jin Seok Heo ),최성호 ( Seong Ho Choi ),이종 대한소화기학회 2008 대한소화기학회지 Vol.52 No.2
Background/Aims: The purpose of this study was to find the factors predicting the neoplastic polyp of gallbladder and analyze the size criteria associated with malignancy. Methods: A total of 354 subjects with gallbladder polyps confirmed by tissue pathology were included for the analysis. The clinical and radiological features of the polyps were compared between the two groups (neoplastic vs. non-neoplastic) and in the three groups (non-neoplastic vs. adenoma vs. adenocarcinoma). The independent factors associated with malignancy were studied. Results: Of 354 patients, non-neoplastic polyps were observed in 229 (64.7%) patents, adenoma in 85 (24.0%) and adenocarcinoma in 40 (11.3%). The mean diameter of non-neoplastic polyp, adenoma, and adenocarcinoma were 11.3±2.8 mm, 16.0±7.2 mm, and 27.0±8.9 mm, respectively. The mean age of patients with non-neoplastic polyp, adenoma, and adenocarcinoma were 44.8±11.3, 49.9±12.5, and 60.8±9.6, respectively. Age, size of polyp, number of polyp, presence of diabetes, and presence of symptom showed statistically significant difference between the neoplastic polyp and non-neoplastic polyp groups. But only age, size of polyp, number of polyp were statistically independent factors associated with neoplastic polyp (p<0.05). To predict the neoplastic polyp, sensitivity was 94.4%, but specificity was 18.3% on the basis of 10 mm criteria. whereas sensitivity and specificity was 76.0% and 55.5% on the 12 mm-criteria. Conclusions: On the basis of our analysis, the size of polyp is the most important factor to predict the malignancy. In the 10 mm criteria, sensitivity is satisfactory but specificity is very low. Therefore 10 mm size should not be considered to be the absolute size-criterion for surgery. (Korean J Gastroenterol 2008;52:97-105)
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심원보,김미옥,김형권,강남욱,강창원,오성욱,조만종,최겸 대한내과학회 1995 대한내과학회지 Vol.49 No.6
Myotonic dystrophy is a multisystemic disorder inherited as an autosomal dominant trait. The characteristic clinical features include the presence of myotonia, atrophy of the muscles of the face and numerous nonmuscular manifestations such as cataracts, frontal baldness, gonadal dysfunctions and cardiac abnormalities. We experienced one case of myotonic dystrophy with atrial fibrillation, intraventricular conduction defect and mitral valve prolapse in 36-year-old male who was admitted because of dyspnea, palpitation and cyanosis. We present this case with reviewing literatures.
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