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RBL 2H3 비만세포에서 히스타민 유리와 칼슘과의 관계
박성훈,김수정,김정민,박주현,최방실,이지윤,최미영,심상수,Park, Sung-Hun,Kim, Soo-Jeong,Kim, Jung-Min,Park, Ju-Hyun,Choi, Bang-Shil,Lee, Ji-Yun,Choi, Mi-Yeong,Sim, Sang-Soo 대한약학회 2007 약학회지 Vol.51 No.1
To investigate the relation between extracellular Ca$^{2+}$ and histamine release, we observed agonist-induced histamine release from RBL 2H3 mast cells in the presence or absence of extracellular Ca$^{2+}$ concentration. Histamine release induced by melittin and thapsigargin were greater in the presence of extracellular Ca$^{2+}$ than in the absence of extracellular Ca$^{2+}$. Econazole-induced histamine release had nothing to do with extracellular Ca$^{2+}$, whereas arachidonic acid-induced histamine release increased in the absence of extracellular Ca$^{2+}$. Calmodulin antagonists did not affect melittin-induced histamine release but they may potentiate arachidonic acid-induced histamine release. These data suggest that arachidonic acid-induced histamine release may be mediated via Ca$^{2+}$-independent pathway and may be potentiated by the block of Ca$^{2+}$-dependent pathway.
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이어(李漁)의 복장론(服裝論) 소고(小考) ― ≪한정우기(閑情偶寄)·성용부(聲容部)≫의 <치복(治服)>을 중심으로
박성훈 ( Park Sung-hun ) 고려대학교 중국학연구소 2017 中國學論叢 Vol.57 No.-
Li Yu, who lived between Late-Ming Dynasty and Qing Dynasty, was a famous drama theorist, writer, thinkers, aesthetician in Ming and Qing Dynasties. “Xian Qing Ou Ji(≪?情偶寄≫)” was one of the most important works in his life. Li Yu`s “Xian Qing Ou Ji” has been paid attention since being published. The discussion of its opera theory in certain chapters in which Ciand Qu Department(<詞曲部>), Exercise and Performance Department (<演習部>), and Voice and Appearance Department (<聲容部>) is fine and original, insightful and they have a far-reaching impact. Li Yu`s thought of dress aesthetics is mainly concentrated in Voice and Appearance Department (<聲容部>). From the dress ideology in “XianQing Ou Ji”, with times and environment which this book is published and author`s special life experience. The full text is divided into three parts: foreword, text, and conclusion. The foreword mainly introduces the significance of the subjects for this article, the research angle. Beginning with the problems he put on dress is of rich and deep the classical dress aesthetics. In his thoughts, human plays a leading role in dressing. Dress will never be independent system beyond body. It is beautiful only when it is matched with skin color, figure, and social status. In Li Yu`s opinion dress ideologies are natural and harmonious. According to his views, beauty lies in naturalness. The more nature the women appear to be when they`re wearing the clothes, the more beautiful they are. What`s more, this beaut still can properly conceal the fault of the women dressed, which make more contribution to the creation of the women`s natural beauty. Also he proposed a principle on ladies elegant and fit made an aesthetic analysis of black color. Li Yu especially admired the color of cyan, which he thought was proper for the rich or the poor, the old or the young, the dark or the fair skin. From the whole view his dress aesthetics are moderate and harmonious and natural. The conclusion excavates Li Yu`s unique contribution to the dress aesthetics theory. And summarizes the characteristics of dress ideology theory in “XianQing Ou Ji” and explores its influence on the dress theory of later generation and points out its limitation.
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박성훈(Sung Hun Park),강창욱(Chang Wook Kang) 한국산업경영시스템학회 2012 한국산업경영시스템학회지 Vol.35 No.3
Companies strive for quality improvement and use process data obtained through measurement process to monitor and control the process. Measurement data contain variation due to error of operator and instrument. The total variation is sum of product variation and measurement variation. Gage R&R is for repeatability and reproducibility of measurement system. Gage R&R study is usually conducted to analyze the measurement process. In performing the gage R&R study, several parameters such as the appropriate number of operators (o), sample size of parts (p), and replicate (r) are used. In this paper we propose how to determine the optimal combination of number of operators (o), sample size of parts (p), and replicates (r) considering measurement time and cost by statistical method.
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박성훈(Park Sung-Hoon),이웅균(Lee Ung-Kyun),조훈희(Cho Hun-Hee),강경인(Kang Kyung-In) 대한건축학회 2009 大韓建築學會論文集 : 構造系 Vol.25 No.10
A steel structure construction system requires a significant amount of skilled labor and its erection is very dangerous. In order to resolve these problems, many automated construction devices and systems have been developed. However, these devices and systems are seldom used in construction works in Korea. One of the reasons for this situation is due to the insufficient economic analysis carried out by researchers when they are being developed. In this study, a model is proposed for analyzing the performance standards of an Robot based Automated Construction System(RCA) for economic feasibility. In addition, the development of the model is adapted to analyze the performance needs of the RCA. The prediction of the working time of the bolting robot for the case study showed that total working times were shorter than normal times when automation cost was the same or less than the normal cost. Through a sensitive analysis, the case that adapts the highest rental fee for the bolting robot and the Construction Factory(CF) brought an economic advantage. This proposed model could contribute to the effective application of the practical use of RCA.
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박성훈 ( Sung Hun Park ),김대철 ( Dae Cheol Kim ) 한국생산성학회 2015 生産性論集 Vol.29 No.1
The purpose of the study is to verify the presence of congestion in the operations of public hospitals in South Korea. Moreover, the differences in congestion and efficiency among the types(foundation type/treatment function) of public hospitals are analyzed. To do these, a DEA model is developed and “the 2013 National Public Hospital Guidance” that was provided by the Public Health Support Unit of National Medical Center is utilized. For the DEA model of congestion and efficiency, the following five inputs are selected: number of doctors, number of nurses, number of medical technicians, number of administrative staffs and number of sick-beds. As for the outputs for the analyses of congestion and efficiency, number of hospitalized patients, number of outpatients and medical profits are considered. The summary of the major results of the study is as follows. First, we find that there are congestions in the operations of public hospitals. For each input, public hospitals generally show a high rate of congestion occurrence as well as a large size of congestion in the operations. There are some differences in the congestion among the foundation types of public hospitals. The national hospitals are found to have a larger occurrence rate and the size of congestion than the special corporate hospitals and geriatric hospitals with respect to every input except for the number of medical technicians. As for the types of treatment function, the special medical treatment-centric (diseases) hospitals are found to have a larger size of congestion than the general medical treatment-centric hospitals and elderly-specialized hospitals in all the inputs. Second, in the case of the differences in the efficiency among the foundation types of public hospitals, the special corporate hospitals show the highest efficiency, followed by the geriatric hospitals and the national hospitals. As for the types of treatment function, the general medical treatment-centric hospitals are found to have a higher degree of efficiency than the elderly-specialized hospitals. The followings state the contributions of the study. First, in this research, the congestion of public hospitals of South Korea is measured and the existence of the congestion is verified for the first time by leveraging the congestion DEA model which would measure the special case of an inefficient situation. These results provide the practical implication that could help determine the priority of management by comparing the congestion for each input. Second, the differences in the efficiency among the types of foundation and treatment function are also analyzed. This achievement helps to establish a foundation which could enhance the understanding of the public hospitals by the environmental factors.
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무작위 속도 변화에 의한 트레드밀 보행훈련이 뇌졸중 환자의 폐기능에 미치는 영향
박성훈 ( Sung-hun Park ),차용준 ( Yong-jun Cha ),최윤희 ( Yoon-hee Choi ) 대한물리의학회 2016 대한물리의학회지 Vol.11 No.4
PURPOSE: The purpose of this study was to investigate which treadmill walking training mode is more effective strategy for improving pulmonary function of persons with chronic stroke. METHODS: Twenty-one chronic stroke patients were allocated and randomly to an experimental group (treadmill training with randomized speed control, n=11) and a control group (treadmill training without speed change, n=10). All participants received 30 minutes of neurodevelopmental treatment. In addition, the two groups performed treadmill training for 20 minutes each time with or without speed change. Speed change was applied 40%, 50%, 60%, 70% of Heart Rate Reserve. All the exercise programs lasted six weeks, with five times per week. Pulmonary function was assessed before and after exercise program by using forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and maximal voluntary ventilation (MVV). RESULTS: In the both groups, FEV1 was significantly increased after training (p<.05). Compared to the control group, the experimental group showed 11.9% larger amount of change (p<.05). In the experimental group, FVC and MVV were significantly increased after training (9.9%, 7.6%, respectively) (p<.05). But in the control group, there was no significant difference in the FVC and MVV after training. CONCLUSION: Treadmill training with randomized speed control will be a better positive rehabilitation program than treadmill training without speed change to improve pulmonary function in persons with chronic stroke.
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