악관절의 비정복성관절원판변위의 수조작 정복에 대한 이개측두신경 전달마취의 효과

김숙영,김지연,홍수민,김병국,박병주,임영관,Kim, Sook-Young,Kim, Ji-Yeon,Hong, Su-Min,Kim, Byung-Gook,Park, Byung-Ju,Im, Yeong-Gwan 대한안면통증구강내과학회 2011 Journal of Oral Medicine and Pain Vol.36 No.1

Aim: Disc displacement without reduction of the temporomandibular joint (TMJ) has been managed by mandibular manipulation to reduce the displaced disc but with a low success rate. The purpose of this study was to determine whether auriculotemporal nerve block anesthesia had an effect on the reduction of the displaced disc and to analyze the factors that influenced the result. Methods: 112 patients were diagnosed with disc displacement without reduction and treated by mandibular manipulation. Disc was recaptured in 35 patients. Among the 77 patients with whom disc recapture had failed, the auriculotemporal nerve was blocked with a local anesthetic in the 49 patients (mean $age \;{\pm}\; SD\; =\; 34.4\;{\pm}\; 15.1$; male 24, female 25) and then mandibular manipulation was performed again. Factors including age, elapsed time from the onset, and opening amount were analyzed in association with disc reduction rate with the auriculotemporal nerve block. Results: Among 49 patients who did not respond to manipulation only, manual reduction with auriculotemporal nerve block anesthesia was successful in 19 patients (38.8%). Maximum unassisted opening amount significantly increased in the 19 patients with successful recapture of the disc ($mean \;{\pm}\; SD\; =\; 46.1 \;{\pm}\; 4.5\; mm$), in contrast to the limited opening amount of the 49 patients before local anesthesia of the auriculotemporal nerve ($mean \;{\pm}\; SD\; =\; 25.7 \;{\pm}\; 6.0\; mm$). Age, elapsed time after the onset, and preoperative opening amount were not associated with the reduction rate. Conclusion: The results of this study suggest that auriculotemporal nerve block anesthesia increases the reduction rate of the disc displacement without reduction of the TMJ when combined with mandibular manipulation, and such anesthesia should be applied at the first stage of manual treatment of disc displacement without reduction.

자료 통계 분석을 위한 MS 엑셀의 유용한 기능들에 관한 사례연구 (지하철 이용객 자료 분석)

김숙영,Kim, Sook-Young 한국컴퓨터산업학회 2008 컴퓨터産業敎育學會論文誌 Vol.9 No.5

A case study to show MS Excel's convenient and powerful functions was conducted to test hypotheses with subway data. Quantitative variables were described using descriptive menu, and qualitative variables were described using histogram menu of a MS Excel software. Relationships were tested using regression menu, differences were tested using t-test menu, and factors were tested using variance-layout menu of a Excel software. Data input, management, and statistical analysis were done successfully with only a MS Excel software. 엑셀이 자료 통계 분석에서 매우 편리하고 유용한 도구가 될 수 있음을 보여주기 위하여 지하철 이용객 자료로 가설을 검정하는 사례 연구를 시행하였다. 양적 자료는 엑셀의 기술통계량 메뉴에 의하여, 질적 자료는 히스토그램 메뉴에 의하여 기술되었고, 변수들간의 관계성 검정은 회귀 분석 메뉴에 의하여, 차이 검정은 T검정 메뉴에 의하여, 요인 검정은 분산배치법 메뉴에 의하여 전문적인 결과를 얻을 수 있었다. 엑셀만을 이용하여 자료 입력, 관리 및 통계 분석 결과를 편리하게 수행할 수 있는 사례가 되었다.

흰 쥐 Strain에 따른 간 마이크로좀의 Cytochrome P-450 동위 효소 특성

김숙영,박기현,Kim, Sook-Young,Park, Ki-Hyun 생화학분자생물학회 1986 한국생화학회지 Vol.19 No.3

Cytochrome P-450 (P-450) 동위 효소 유도 물질로서 phenobarbital (PB) 또는 3-methylcholanthrene (MC)을 처리한 흰 쥐 strain (Sprague-Dawley, Fischer, Wistar)의 간 마이크로좀에서 총 P-450 함량, aryl hydrocarbon hydroxylase 활성도의 유도 정도 및 P-450 동위 효소의 구성비 등은 strain에 따라 다소 차이를 보였으나, P-450-b type은 PB에 의해, c type은 MC에 의해 주로 유도되었으며, 이들 동위 효소의 기질 특이성, 단일 항체와의 결합에 의한 효소 활성도의 억제, 동위 효소의 항체 결합 부위 등은 strain의 종류와 상관관계가 없는 것으로 보였으며 P-450 동위 효소의 이러한 몇가지 특성들이 strain 사이에서 유전적으로 보존되고 있는 것으로 추정되었다. After i.p. administration of phenobarbital (PB) or 3-methylcholanthrene (MC) on the adult male rat strains, Wistar, Fischer, and Sprague-Dawley, we compared the properties of hepatic microsomal cytochrome P-450 (P-450) isozymes. Total P-450 contents, degree of induction of aryl hydrocarbon hydroxylase (AHH) activity and isozyme pattern of P-450 were slighly dependent on rat strains. The major form of P-450 isozymes in rats tested was P-450-b in the case of PB-microsomes and that of MC-microsomes was P-450-c. Substrate specificity of the isozymes and the inhibition of activity by the binding of P-450-specific monoclonal antibodies to the isozymes were not associated with rat strains. The results obtained from immunological assay using monoclonal antibodies indicated that the sensitivity of hepatic P-450-dependent AHH activity was rather influenced by the treatment of PB or MC as inducers than by the differences of strain. Thus, it seemed that such characteristics of P-450 isozymes have been genetically conserved among rat strains.

MS 엑셀 프로그램의 통계분석결과 신뢰성 검증 및 매크로 보완 (분산분석 메뉴를 중심으로)

김숙영,Kim, Sook-Young 한국컴퓨터산업학회 2008 컴퓨터産業敎育學會論文誌 Vol.9 No.5

초장력 스프레드시트 기능의 엑셀 프로그램에서 자료를 통계적으로 분석하는 데이터분석 메뉴는 엑셀 2000 이후 수정 보완 되고 있지 않으며 그 활용도도 매우 저조하다. 본 연구에서는 엑셀 통계분석 메뉴 활용도 향상을 위하여 사용빈도가 높은 분산분석의 엑셀 메뉴 실행 결과와 계산식에 의한 이론 결과를 비교하고 고차원 분석 매크로를 개발하였다. 실자료를 엑셀 라이터분석 메뉴를 적용하여 얻은 결과와 계산식에 의한 이론 결과는 요인이 한개인 일원배치법이나 두개인 이원배치 법에서 모두 정확히 일치하였다. 즉 엑셀 데이터분석 메뉴의 신뢰성이 검증되었다. 고차원적인 분산분석법인 블록화된 분산분석 결과를 제공하는 매크로 및 일원분산분석법에서 평균 차이 있는 그룹들을 찾아내는 다중비교 분석방법 매크로를 엑셀 함수를 이용하여 개발하였다. Statistical analysis menus of MS Excel software, with powerful spreadsheet functions has not been modified since Excel 2000 Edition and its utilization is very low. To improve utilization of Excel menu for statistical analysis, this research compared outputs of Excel statistical menus and computed test statistics, and developed high-level macros. Outputs of Excel menus, both oneway layout and twoway layout, on real data are exactly same as the computed test statistics, and therefore, Excel menus for statistical analysis are reliable. Macros to provide results for Analysis of Variance with a block and multiple comparison of means are developed using Excel functions.

유통업 여성 근로자의 건강 문제와 건강 행위에 관한 연구

김숙영,윤순녕,Kim, Souk-Young,Yun, Soon-Nyung 한국지역사회간호학회 2000 지역사회간호학회지 Vol.11 No.1

The objectives of this study are to identify health behaviors and health problems. and the relations between health behaviors and health problems of female workers in the retail business. The number of subjects were 200 female workers of 6 department stores in Seoul and Kyonggi area, whose jobs last more than 6 months as retail employees. The data was collected during 2 months from July 1 to August 30, 1998. The Cornell Medical Index Health Questionnaire(CMI) was used to measure their health problems, while health behaViorn were investigated in terms of 'smoking', 'alcohol', exercise', 'diet', and 'sleeping'. The data were analyzed with frequency. percentage, t-test, ANOVA test, and $X^2-test$ by SPSS PC+ program. The results of this study are as follows: 1. Out of health problems. Digestive symptoms occupied the highest percent number. nervous ones the second and cardiovascular ones the third among physical health problems of retail female workers. The most frequent mental health problem was 'adequacy' and the next, 'tension' and 'anger', 2, Health problems according to general characteristics of subjects were shown that the younger or the unmarried complained more than the older or the married, especially in the items of 'eye and ear', 'respiratory system', 'cardiovascular system', 'digestive tract', 'nervous system', 'adequacy', and 'depression'. The longer working duration they have had, the more they complained of 'respiratory system' and 'adequacy'. The lower academic careers complained of 'nervous' than the higher ones with statistical significance. 3. The analysis of daily health clinic notes showed that respiratory complaints were the highest percent, successively followed by digestive tract, nervous one, external injury, musculoskeletal system, urinary-reproductive system and others. 4. The level of their health practice was generally low in smoking, diet habit and alcohol intake, exercise, sleeping, very low especially in smoking, diet, alcohol intake, and exercise among them all. 5. Present smokers and ones with past experience complained of physical and mental health problems of 'respiratory system', 'digestive tract', 'skin', 'nervous', 'urinary-reproductive system', 'fatigability', adequacy', 'depression', 'anxiety', 'anger' and 'tension', than non smokers, with statistical difference. Workers without having breakfast and with irregular diet had more complaints on 'digestive tract', 'adequacy' and 'tension', than those who had regular dietary habit. The less the subjects slept, the more they complained of eye and ear, cardiovascular system. The subjects who drank alcohol complained more digestive problem. However, whether they exercise or not did not affect physical and mental health problems in a significant manner. 6. The subjects' age and marital status were statistically significant relating to health behaviors, as the younger or unmarried recorded a low level of health practice in smoking, drinking, dietary habit. Based on the results, the suggestions are made as follows: 1. Health education program on smoking, alcohol intake, diet habit is needed to improve health problems and health behavior of female retail workers. 2. The unmarried workers of late teen and twenties, who are transitional period from teenagers to adulthood are important targets for health promotion program especially for maternal health. 3. Better working environment with sufficient time and facilities for workers to relax is required to promote female sales workers' health. 4. Further research is required to identify the relation between workers' visual fatigue and intense lights for the display of goods.

최신의학상식-외상 후 스트레스 장애

김숙영,Kim, Suk-Yeong 한국산업간호협회 2008 한국산업간호협회지 Vol.15 No.1

Flavone 투여로 흰쥐간에서 유도된 Microsomal Cytochrome P - 450 의 특성

김숙영,이동욱,박기현 ( Sook Young Kim,Dong Wook Lee,Ki Hyun Park ) 생화학분자생물학회 1990 BMB Reports Vol.23 No.4

Cytochrome P-450 (P-450) isozymes of flavone-pretreated rats were compared with those of partially purified microsomal proteins and liver microsomes from control rats and phenobarbital (PB)-, 3-methylcholanthrene(MC)-, and isosafrole(ISF)-pretreated rats. The activities of microsomal P-450 dependent aryl hydrocarbon hydroxylase(AHH) and ethoxycoumarin deethylase(ECDE) were more than three times of those of control. AHH and ECDE activities of partially purified P-450 with DE_(52) column chromatography were increased more than eight times of control. Monoclonal MC 1-7-1 antibody, which is specific to P-450 c and d isozyme, bound specifically to liver microsomal P-450 of flavone-rats in radioimmunoassay. Some properties of P-450 of flavone-rats were identical with those of P-450 d in spectral and electrophoretic studies. The absorption maximum of P-450-CO complex of flavone-rats was 448 nm (same as that of MC-pretreated rats), and molecular weight of partially purified P-450 from the major band of electrophoresis was 52,000 (same as that of PB-pretreated rats). Thus, it can be indicated that the pretreatment of flavone induces P-450 d or P-450 isozyme with similar immunochemical properties to P-450 d.

흰 쥐 간으로부터 분리된 Microsomal Cytochrome P - 450 dependent Monooxygenase 의 안정성

김숙영,박기현 ( Sook Young Kim,Ki Hyun Park ) 생화학분자생물학회 1988 BMB Reports Vol.21 No.4

The stability of cytochrome P-450, cytochrome b_5, cytochrome P-450-dependent monooxygenases, and NADPH-cytochrome P-450 reductase was observed in liver microsomes prepared from rats pretreated with β-naphthoflavone during the stored period of 8 months at -80℃. The contents of P-450 and b_5 were not changed significantly and the activities of aryl hydrocarbon hydroxylase, 7-ethoxycoumarin ο-deethylase, and benzphetamine demethylase were also stable for this period. However, the activities of NADPH-cytochrome P-450 reductase were increased gradually, whereas since 5th month, those of testosterone hydroxylases including 16α-hydroxylase were decreased. The decrease seems due to a certain change in testosterone binding site of P-450, not to the inactivation of one isozyme of P-450.

제언 - 노동자 생명 지키기 프로젝트

김숙영,Kim, Suk-Yeong 대한산업보건협회 2018 산업보건 Vol.2018 No.-

NIE 프로그램이 중학생들의 과학과 관련된 태도와 학업 성취도에 미치는 영향

김숙영,최성희,Kim, Sug-Young,Choi, Seong-Hee 한국지구과학회 2000 한국지구과학회지 Vol.21 No.4

이 연구의 목적은 중학교 2학년 물의 순환과 일기의 변화 단원에 대해 STS의 한 방법인NIE 수업자료를 개발하여 학생들에게 처치한 후, NIE가 학업 성취도와 과학 관련 태도에 미치는 효과를 조사하고 학습 방법과 학생들의 학업 능력 수준간의 상호 작용 효과를 알아보고자 하는 것이다. 연구대상은 서울시 동작구에 소재한 여자 중학교 2학년 4개 반을 임의로 선정했고, 학급별로 실험집단과 통제집단에 2학급씩 무작위로 배치하였다. 실험 집단에서는 교사가 관련 개념을 6차시동안 간략하게 강의하고 나머지 7차시동안 개발한 NIE 수업자료로 수업하였고, 통제 집단에서는 전통적인 교과서 위주의 강의식 수업을 하였다. NIE 수업은 Iowa Chautauqua Program에서 활용한 문제로의 초대, 탐색 , 설명, 해결방안의 제시 단계에 따라 진행하였고, STS 학습 지도 전략 중 과학에서 출발하는 접근법으로 프로젝트학습, 토픽학습, 낱말 맞추기 퍼즐 등의 NIE 수업자료를 개발 활용하였다. 학업 성취도 검사 도구는 차시별 수업 목표를 고려하여 연구자가 개발하였고, 과학 관련 태도 검사 도구는 TOSRA의 7가지 영역 중 두 영역, 즉 과학의 사회적 의미와 과학에 대한 흥미적 관심에 해당하는 20문항을 사용하였다. 연구 결과에 의하면, NIE 자료를 활용한 수업이 교과서 위주의 전통적인 수업에 비해 학생들의 학업 성취도를 향상시키는데 효과적이었다(P<.01). 또한, 과학과 관련된 학생들의 태도 변화에 있어서도 실험집단이 통제집단보다 통계적으로 유의미한 성취도의 우위를 보이는 것으로 나타났다(P<.01). 학습 방법과 학생들의 성취 수준간의 상호 작용 효과를 알아본 결과 학업 성취도와 과학에 대한 흥미적 관심의 경우에는 주목할 만한 상호 작용 효과는 나타나지 않았으나, 과학의 사회적 의미에 대한 태도에 있어서는 NIE 수업 방법이 전통적인 수업 방법에 비해 하위 집단의 태도를 보다 더 긍정적으로 함양시킨 결과를 유도했다. The purpose of this study is to develope and apply NIE programs related to sub-chapter 'The Change of Weather and Circulation of Water' in 2nd grade science text book of middle school, and thereby to investigate the effects of NIE approach on science-related attitude and teaming achievement of students, and interaction between treatment methods and students' learning ability. Subjects consisted of 2nd grade students of four classes in a girls middle school located at the southern part of Seoul. Four classes were divided into experimental and control groups by two classes randomly. The experimental groups have been instructed on the related-general concepts for six times and then received seven NIE programs developed by researcher for seven times. The control groups have received the instruction through the conventional teaching method. The NIE learning has been progressed following the steps using in the Iowa Chautaugua Program, e.g. invite, explore, propose explanation and solutions, and take action. NIE programs, e.g. project studying, topic studying and a crossword puzzle have been developed and applied using 'science first' approach of the STS instruction. Twenty questions related to social implications of science and leisure interest in science within seven frameworks of TOSRA have been used in this study as an evaluation instrument of science-related attitude. Learning achievement has been evaluated using an instrument developed by researcher. The results of this study can be summarized as follows. (1) NIE approach was more effective in progressing learning achievement of middle school students than conventional teaching method (p<.01). (2) Experimental groups show statistically significant improvement on science-related attitude than control groups (p<.01). There were no significant interactions between treatment methods and students' learning ability on learning achievement and leisure interest in science. The NIE approach were more effective than the conventional one on social implications of science, especially to low ability students.