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이명호 ( Myong Ho Lee ),정성수 ( Sung Soo Jung ),홍관표 ( Kwan Pyo Hong ),김태환 ( Tae Hwan Kim ),전재범 ( Jae Bum Jun ),이인홍 ( In Hong Lee ),배상철 ( Sang Cheol Bae ),유대현 ( Dae Hyun Yoo ),김성윤 ( Seong Yoon Kim ),김목현 ( M 대한류마티스학회 1997 대한류마티스학회지 Vol.4 No.1
Object: To investigate the characteristics of diffuse idiopathic hyperostosis (DISH) in Koreans. Methods: The nine patients of DISH were investigated in terms of symptom, involved area in simple X-ray, accompaning disease, serum uric acid level, and serum triglyceride and cholesterol. Results: Eight of nine patients were male, one patient was female, and their mean age was 64. Their symptoms were no symptom (2/9), neck pain (2/9), dorsal pain (2/9), and low back pain (3/9). The involved areas were the cervical vertebrae (1/9), the lower thoracic vertebrae (3/9), or the lower thoracic and upper lumbar vertebrae(5/9). The accompaning diseases were ankylosing spondylitis (1/9), degenerative joint disease (2/9), posterior laminectomy (1/9), diabetes mellitus (1/9), chronic active hepatitis (1/9), cerebrovascular accident (2/9), hypertension (2/9), chronic renal failure (2/9), and gout (2/9). In the cases involving thoracic vertebrae, the ossification was seen dominantly in the right side. Four of nine patients had diabetes mellitus, hyperuricemia (7.0 mg/dl in male and 6.6 mg/dl in female), or dyslipidemia (194 mg/dl in serum triglycerid level and 275 mg/dl in serum cholesterol level). Conclusions: In our cases of DISH, it was dominant in male and old age, and the diabetes mellitus or hyperuricemia was more frequently found than in general population.
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방사성동위원소옥소(131I)에 의한 갑상선질환의 임상적연구
정경태,이문호,이범홍,김목현,장고창,김명재,이장규 대한핵의학회 1967 핵의학 분자영상 Vol.1 No.1
$quot;서울대학교 의과대학 부속병원 방사성동위원소진료실에서 1960년 5월부터 1966년 6월까지 진료한 1,716명의 각종 갑상선 질환 환자에 대하여 131I에 의한 각종 갑상선기능검사를 실시하는 동시에 갑상선 기능항진증에 대한 131I의 치료성적을 종합검토하여 아래와 같은 결론을 얻었다. 1) 1,716예의 갑상선질환중 중독성미만성선종이 596명 (34.7%)으로 가장 많았으며 비중독성결절성선종이 412명 (24.0%), 정상기능이 278명 (16.2%), 비중독성미만성선종이 236명 (13.8%), 기능저하가 89명 (5.2%), 중독성결절성선종이 53명 (3.1%), 갑상선염이 32명 (1.9%), dyshormonogenesis가 20명 (1.2%)이었다. 2) 갑상선질환의 성별 발생빈도는 남자 218명 (12.7%), 여자 1,498명 (87.3%)로 그 비는 1:6.9이었다. 3) 연령별 발생빈도는 20∼40대가 1,365명으로 가장 많았으며 이는 전예의 79.6%이었다. 4) 각종 갑상선기능검사중 131I 갑상선섭취율, 131I 혈청내방사능, T3 시험, PB131I 전화율, BMR 등의 진단적가치를 논하고 각 검사의 정상범위에 대하여 고찰하였다. 5) 갑상선 기능항진증예 545명에 대한 131I의 완치율은 초회에 68.3%, 2회에 92.3%이었으며 1회 투여량은 6mC가 가장 많았다. 6) 131I 투여$quot; Over the past 6 years, from May 1960 to June 1966, 1,716 patients with various diseases of thyroid were examined and thyroid function tests with 131I were done. Among them, 545 patients with hyperthyroidism were treated with (131)^I. A summary of the clinical data of the (131)^I-thyroid function tests and the therapeutic results of (131)^I were presented and discussed. 1) The patients examined consisted of;596 cases (34.7%) with toxic diffuse goiter, 412 cases (24.0%) with non-toxic nodular goiter, 278 cases (16.2%) with euthyroidism, 236 cases (13.8%) with non-toxic diffuse goiter, 89 cases (5.2%) with hypothyroidism, 53 cases (3.1%) with toxic nodular goiter, 32 cases (1.9%) with thyroiditis and 20 cases (1.2%) with dyshormonogenesis. 2) There were 218 (12.7%) male patients and 1,498 (87.3%) female patients, showing a ratio of 1:6.9, female predominantly. 3) The majority of patients (79.6%) were in the 3rd through 5th decades of their lives showing the peak in the 4th decades (35.9%). 4) The diagnostic values and normal ranges of (131)^I uptake test, 48 hour serum activity, T3 red blood cell uptake and PB131I conversion ratio were discussed. 5) An attention was given to dyshormonogenesis, a qualitative hypothyroidism, due to its characteristic findings of clinical and (131)^I thyroid function tests, and its pathogenesis was briefly reviewed. 6) Among 545 patients with hyperthyroidism treated with (131)^I, 68.3% was cured after single therapeutic dose and another 24.0% was cured after second dose. 7) The complications of (131)^I therapy were discussed in some details and myxedema had developed in 3.9% of our cases. No thyroid cancer was found after (131)^I therapy.
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金榮順,金剛石,朴陞哲,李禎均,朴炅南,金穆鉉 中央醫學社 1975 中央醫學 Vol.28 No.4
Behscet's disease is an obscure disorder characterized by ulceration of the mouth and genitalia, and involvement of the eyes including uveitis and iridocyclitis, and the nervous system is also involved. Recently the chararteristics of the autoimmune disease regarding pathogenesis have been exclaimed in relatively broad multisystems. A 44 year old female was admitted with complaint of incidiously progressive aphthous ulceration of the mouth and ulceration of the vagina for 30 years duration, erythema nodosum for 15 years, and conjunctivitis with iridocyclitis for 9 years. She had suffered from neurologic manifestations, which began one year previously. She was given with conservative measures, and corticosteroid with poor improvement.
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